MX388726B - Derivados de benzodiazepina, composiciones y métodos para tratar deterioro cognitivo. - Google Patents
Derivados de benzodiazepina, composiciones y métodos para tratar deterioro cognitivo.Info
- Publication number
- MX388726B MX388726B MX2019007338A MX2019007338A MX388726B MX 388726 B MX388726 B MX 388726B MX 2019007338 A MX2019007338 A MX 2019007338A MX 2019007338 A MX2019007338 A MX 2019007338A MX 388726 B MX388726 B MX 388726B
- Authority
- MX
- Mexico
- Prior art keywords
- sub
- cognitive impairment
- compositions
- containing gaba
- age
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662436272P | 2016-12-19 | 2016-12-19 | |
| PCT/IB2017/001763 WO2018130869A1 (en) | 2016-12-19 | 2017-12-20 | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| PCT/IB2017/001762 WO2018130868A1 (en) | 2016-12-19 | 2017-12-20 | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019007338A MX2019007338A (es) | 2019-09-19 |
| MX388726B true MX388726B (es) | 2025-03-20 |
Family
ID=62557208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019007338A MX388726B (es) | 2016-12-19 | 2017-12-20 | Derivados de benzodiazepina, composiciones y métodos para tratar deterioro cognitivo. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20180170941A1 (https=) |
| EP (1) | EP3555100B1 (https=) |
| JP (1) | JP7153938B2 (https=) |
| CN (2) | CN110382501A (https=) |
| AU (1) | AU2017393082B2 (https=) |
| CA (1) | CA3047684A1 (https=) |
| EA (1) | EA201991497A1 (https=) |
| IL (1) | IL267451B2 (https=) |
| MX (1) | MX388726B (https=) |
| WO (2) | WO2018130869A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ760341A (en) | 2013-12-20 | 2021-12-24 | Agenebio Inc | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| MX392119B (es) | 2015-06-19 | 2025-03-11 | Agenebio Inc | Derivados de benzodiazepina, composiciones y metodos para tratar deterioro cognitivo |
| US11505555B2 (en) | 2016-12-19 | 2022-11-22 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| US20180170941A1 (en) | 2016-12-19 | 2018-06-21 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| CN112601749B (zh) * | 2018-06-19 | 2024-03-26 | 艾吉因生物股份有限公司 | 用于治疗认知损害的苯并二氮杂环庚三烯衍生物，组合物和方法 |
| WO2020072675A1 (en) | 2018-10-02 | 2020-04-09 | Northwestern University | Beta-carbolines as positive allosteric modulators of the human serotonin receptor 2c (5-ht2c) |
| JP7737721B2 (ja) * | 2019-12-19 | 2025-09-11 | エージンバイオ， インコーポレイテッド | 認知障害を処置するためのベンゾジアゼピン誘導体、組成物および方法 |
| CN116075302A (zh) * | 2020-07-10 | 2023-05-05 | 艾吉因生物股份有限公司 | GABAAα5激动剂和SV2A抑制剂的组合以及在认知损害的治疗中的使用方法 |
| WO2022011314A1 (en) * | 2020-07-10 | 2022-01-13 | Agenebio, Inc. | POLYMORPHS OF A GABAA α5 AGONIST AND METHODS OF USING IN THE TREATMENT OF COGNITIVE IMPAIRMENT |
| CN113413532B (zh) * | 2021-07-01 | 2022-03-01 | 曾迎春 | 基于虚拟现实的癌症相关认知障碍评估与康复训练系统 |
| CN120584115A (zh) | 2022-08-19 | 2025-09-02 | 艾吉因生物股份有限公司 | 苯并氮杂䓬衍生物、组合物和用于治疗认知损害的方法 |
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| NZ760341A (en) * | 2013-12-20 | 2021-12-24 | Agenebio Inc | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| WO2016191288A1 (en) | 2015-05-22 | 2016-12-01 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
| MX392119B (es) | 2015-06-19 | 2025-03-11 | Agenebio Inc | Derivados de benzodiazepina, composiciones y metodos para tratar deterioro cognitivo |
| US20180170941A1 (en) | 2016-12-19 | 2018-06-21 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| CN108567786A (zh) | 2017-03-10 | 2018-09-25 | 陈洪国 | 一种治疗溃疡性结肠炎的药物组合物 |
| CN108567787A (zh) | 2017-03-10 | 2018-09-25 | 辛衍雪 | 一种治疗慢性阻塞性肺病的药物组合物 |
| CN112601749B (zh) | 2018-06-19 | 2024-03-26 | 艾吉因生物股份有限公司 | 用于治疗认知损害的苯并二氮杂环庚三烯衍生物，组合物和方法 |
| JP7737721B2 (ja) * | 2019-12-19 | 2025-09-11 | エージンバイオ， インコーポレイテッド | 認知障害を処置するためのベンゾジアゼピン誘導体、組成物および方法 |
-
2017
- 2017-12-19 US US15/847,906 patent/US20180170941A1/en not_active Abandoned
- 2017-12-20 CN CN201780086584.0A patent/CN110382501A/zh active Pending
- 2017-12-20 AU AU2017393082A patent/AU2017393082B2/en active Active
- 2017-12-20 EA EA201991497A patent/EA201991497A1/ru unknown
- 2017-12-20 CN CN202310213936.1A patent/CN116640143A/zh active Pending
- 2017-12-20 MX MX2019007338A patent/MX388726B/es unknown
- 2017-12-20 WO PCT/IB2017/001763 patent/WO2018130869A1/en not_active Ceased
- 2017-12-20 WO PCT/IB2017/001762 patent/WO2018130868A1/en not_active Ceased
- 2017-12-20 CA CA3047684A patent/CA3047684A1/en active Pending
- 2017-12-20 IL IL267451A patent/IL267451B2/en unknown
- 2017-12-20 EP EP17891696.1A patent/EP3555100B1/en active Active
- 2017-12-20 JP JP2019554038A patent/JP7153938B2/ja active Active
-
2022
- 2022-09-02 US US17/902,374 patent/US12528819B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| NZ755287A (en) | 2025-06-27 |
| IL267451A (en) | 2019-08-29 |
| US20180170941A1 (en) | 2018-06-21 |
| WO2018130868A1 (en) | 2018-07-19 |
| JP2020512389A (ja) | 2020-04-23 |
| IL267451B1 (en) | 2023-06-01 |
| EP3555100A4 (en) | 2020-06-10 |
| WO2018130868A8 (en) | 2019-08-08 |
| CN116640143A (zh) | 2023-08-25 |
| AU2017393082B2 (en) | 2022-04-21 |
| JP7153938B2 (ja) | 2022-10-17 |
| EA201991497A1 (ru) | 2020-01-20 |
| US20230134844A1 (en) | 2023-05-04 |
| AU2017393082A1 (en) | 2019-07-25 |
| WO2018130869A1 (en) | 2018-07-19 |
| IL267451B2 (en) | 2023-10-01 |
| MX2019007338A (es) | 2019-09-19 |
| EP3555100B1 (en) | 2023-05-10 |
| US12528819B2 (en) | 2026-01-20 |
| CN110382501A (zh) | 2019-10-25 |
| CA3047684A1 (en) | 2018-07-19 |
| EP3555100A1 (en) | 2019-10-23 |
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