MX385305B - Composiciones de ribósido de nicotinamida para uso tópico en el tratamiento de afecciones de la piel. - Google Patents
Composiciones de ribósido de nicotinamida para uso tópico en el tratamiento de afecciones de la piel.Info
- Publication number
- MX385305B MX385305B MX2016005574A MX2016005574A MX385305B MX 385305 B MX385305 B MX 385305B MX 2016005574 A MX2016005574 A MX 2016005574A MX 2016005574 A MX2016005574 A MX 2016005574A MX 385305 B MX385305 B MX 385305B
- Authority
- MX
- Mexico
- Prior art keywords
- nicotinamide riboside
- treatment
- compositions
- skin conditions
- skin
- Prior art date
Links
- 235000020956 nicotinamide riboside Nutrition 0.000 title abstract 6
- 239000011618 nicotinamide riboside Substances 0.000 title abstract 6
- JLEBZPBDRKPWTD-TURQNECASA-O N-ribosylnicotinamide Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](CO)O2)O)=C1 JLEBZPBDRKPWTD-TURQNECASA-O 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000000699 topical effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- BAWFJGJZGIEFAR-NNYOXOHSSA-O NAD(+) Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-O 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 230000037041 intracellular level Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000004083 survival effect Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 230000037303 wrinkles Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Physical Education & Sports Medicine (AREA)
- Birds (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361897713P | 2013-10-30 | 2013-10-30 | |
| PCT/US2014/063260 WO2015066382A1 (en) | 2013-10-30 | 2014-10-30 | Nicotinamide riboside compositions for topical use in treating skin conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2016005574A MX2016005574A (es) | 2016-12-09 |
| MX385305B true MX385305B (es) | 2025-03-18 |
Family
ID=53005146
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016005574A MX385305B (es) | 2013-10-30 | 2014-10-30 | Composiciones de ribósido de nicotinamida para uso tópico en el tratamiento de afecciones de la piel. |
| MX2021009652A MX394291B (es) | 2013-10-30 | 2014-10-30 | Composiciones de ribosido de nicotinamida para uso topico en el tratamiento de afecciones de la piel. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021009652A MX394291B (es) | 2013-10-30 | 2014-10-30 | Composiciones de ribosido de nicotinamida para uso topico en el tratamiento de afecciones de la piel. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10688118B2 (enExample) |
| EP (1) | EP3063163B1 (enExample) |
| JP (1) | JP6509844B2 (enExample) |
| KR (3) | KR20210107895A (enExample) |
| CN (2) | CN105873937A (enExample) |
| AU (1) | AU2014342185B2 (enExample) |
| CA (1) | CA2928656C (enExample) |
| ES (1) | ES2925879T3 (enExample) |
| MX (2) | MX385305B (enExample) |
| NZ (1) | NZ719328A (enExample) |
| WO (1) | WO2015066382A1 (enExample) |
| ZA (1) | ZA201603314B (enExample) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015270130A1 (en) * | 2014-06-02 | 2016-12-15 | Glaxosmithkline Intellectual Property (No.2) Limited | Preparation and use of crystalline beta-D-nicotinamide riboside |
| BR112016028672A2 (pt) | 2014-06-06 | 2017-08-22 | Glaxosmithkline Ip No 2 Ltd | análogos de ribosídeo de nicotinamida e composições farmacêuticas e usos do mesmo |
| EP3174891B1 (en) | 2014-07-24 | 2020-01-29 | W.R. Grace & CO. - CONN. | Crystalline form of nicotinamide riboside |
| BR112017019409A2 (pt) | 2015-03-09 | 2018-04-24 | Grace W R & Co | forma cristalina de ribosídeo de nicotinamida |
| MX390185B (es) * | 2015-03-16 | 2025-03-20 | Chromadex Inc | Composiciones de acido nicotinico ribosido o de nicotinamida ribosido, derivados reducidos de los mismos, y su uso. |
| JP2018515485A (ja) | 2015-05-01 | 2018-06-14 | ザ プロクター アンド ギャンブル カンパニー | 皮膚の外観を改善する方法及びニコチンアミドリボシドを使用したそのための組成物 |
| JP6611099B2 (ja) * | 2015-05-01 | 2019-11-27 | ザ プロクター アンド ギャンブル カンパニー | 皮膚の健康を改善する方法及びそのための組成物 |
| JP2018515486A (ja) | 2015-05-01 | 2018-06-14 | ザ プロクター アンド ギャンブル カンパニー | ニコチンアミドリボシドを用いた皮膚外観の改善方法及びそのための組成物 |
| WO2016200447A1 (en) | 2015-06-10 | 2016-12-15 | Elysium Health, Inc. | Nicotinamide riboside and pterostilbene compositions and methods for treatment of skin disorders |
| WO2016210232A1 (en) * | 2015-06-25 | 2016-12-29 | N.V. Perricone Llc | Niacinamide mononucleotide formulations for skin aging |
| US11013678B2 (en) * | 2015-06-29 | 2021-05-25 | The Procter & Gamble Company | Multi-component skin care product |
| US20160374908A1 (en) | 2015-06-29 | 2016-12-29 | The Procter & Gamble Company | Skin care composition and methods of using the same |
| WO2017004100A1 (en) | 2015-06-29 | 2017-01-05 | The Procter & Gamble Company | Encapsulated particles comprising nicotinamide riboside |
| CA3010730C (en) | 2016-01-11 | 2021-02-16 | The Procter & Gamble Company | Method of treating a skin condition and compositions therefor |
| AU2017232930B2 (en) | 2016-03-16 | 2021-03-25 | ChromaDex Inc. | B-vitamin and amino acid conjugates of nicotinoyl ribosides and reduced nicotinoyl ribosides, derivatives thereof, and methods of preparation thereof |
| KR20190008246A (ko) * | 2016-04-20 | 2019-01-23 | 크로마덱스 아이엔씨. | Nad+ 증가용 전구체로서 니코틴산 리보사이드 또는 니코틴아미드 리보사이트 유도체 및 이의 환원된 유도체의 용도 |
| CN115645432A (zh) | 2016-08-22 | 2023-01-31 | 益力舒健康公司 | 用于治疗神经退行性病症的烟酰胺核苷和紫檀芪的组合物和方法 |
| US10689411B2 (en) | 2016-11-11 | 2020-06-23 | The Queen's University Of Belfast | Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof |
| MX2019006278A (es) | 2016-11-29 | 2019-08-21 | Univ Iowa Res Found | Uso de precursores de nad para mejorar la salud materna y/o salud de la descendencia. |
| US11071747B2 (en) | 2016-11-29 | 2021-07-27 | University Of Iowa Research Foundation | Use of NAD precursors for breast enhancement |
| CN110121331B (zh) | 2016-12-21 | 2022-09-16 | 联合利华知识产权控股有限公司 | 含有难溶性化合物的个人护理组合物 |
| WO2018114749A1 (en) | 2016-12-21 | 2018-06-28 | Unilever Plc | Personal care compositions with cystine |
| EP3558246B1 (en) | 2016-12-21 | 2021-10-20 | Unilever IP Holdings B.V. | Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids |
| CA3047495A1 (en) | 2016-12-21 | 2018-06-28 | Unilever Plc | Topical skin lightening additive and composition with amino acids and nicotinamide compounds |
| RU2651047C1 (ru) * | 2017-05-04 | 2018-04-18 | Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" | Лекарственная композиция цитопротекторного действия и способ ее получения |
| US20200085849A1 (en) * | 2017-05-18 | 2020-03-19 | Elysium Health, Inc. | Methods and compositions for improving sleep |
| US11286274B2 (en) | 2017-06-19 | 2022-03-29 | Mitopower Llc | Nicotinamide riboside derivatives and their uses |
| CN114788791A (zh) | 2017-06-23 | 2022-07-26 | 宝洁公司 | 用于改善皮肤外观的组合物和方法 |
| WO2019023471A1 (en) * | 2017-07-28 | 2019-01-31 | Centers For Age Control, Inc. | COMPOSITIONS AND METHODS FOR PREVENTING AND INVERTING THE ASPECTS OF AGING |
| JP7210459B2 (ja) * | 2017-09-14 | 2023-01-23 | めぐみ 田中 | 老化防止剤及び老化防止方法 |
| GB201716391D0 (en) * | 2017-10-06 | 2017-11-22 | Xobaderm Ltd | Kit for delivery of an active compound into a biological barrier |
| CN112020363A (zh) | 2017-12-22 | 2020-12-01 | 益力舒健康公司 | 烟酰胺核苷氯化物的结晶形式 |
| CN112437657A (zh) | 2018-07-03 | 2021-03-02 | 宝洁公司 | 处理皮肤状况的方法 |
| WO2019210607A1 (zh) * | 2018-08-17 | 2019-11-07 | 邦泰生物工程(深圳)有限公司 | 一种稳定型烟酰胺核糖组合物及其制备方法 |
| KR102060374B1 (ko) * | 2018-12-14 | 2019-12-30 | 주식회사 휴메딕스 | 지방알코올 컨쥬게이션된 니코틴아미드 리보사이드 유도체 |
| EP3897666A2 (en) | 2018-12-17 | 2021-10-27 | Mitopower LLC | Nicotinyl riboside compounds and their uses |
| CN114423771A (zh) | 2019-07-19 | 2022-04-29 | 生物合成股份公司 | 制备烟酰胺呋喃核糖苷盐的方法、烟酰胺呋喃核糖苷盐本身及其用途 |
| CN110638827A (zh) * | 2019-10-17 | 2020-01-03 | 泓博元生命科技（深圳）有限公司 | Nadh及其盐在制备皮肤色素抑制剂中的应用 |
| CN111166760A (zh) * | 2019-12-17 | 2020-05-19 | 浙江安赛新材料科技有限公司 | β-烟酰胺单核苷酸或其前体的组合物及制备方法、应用 |
| KR102315139B1 (ko) | 2019-12-17 | 2021-10-20 | 주식회사 휴메딕스 | 지방아민 컨쥬게이션된 니코틴아미드 리보사이드 유도체 |
| CN111184732B (zh) * | 2020-03-04 | 2023-09-08 | 武汉华纳联合药业有限公司 | 一种复合组合物制剂及其制备方法和皮肤炎症中的应用 |
| CN111454311B (zh) * | 2020-04-03 | 2021-10-19 | 深圳市迪克曼科技开发有限公司 | 烟酰胺核糖的有机酸盐及其组合物与制备方法 |
| WO2021234009A1 (fr) * | 2020-05-20 | 2021-11-25 | Nuvamid Sa | Compositions cosmetiques anti-age comprenant du nmn |
| FR3110410A1 (fr) * | 2020-05-20 | 2021-11-26 | Nuvamid Sa | Compositions cosmétiques anti-âge comprenant de la NMN |
| EP4157206A1 (en) | 2020-06-01 | 2023-04-05 | The Procter & Gamble Company | Method of improving penetration of a vitamin b3 compound into skin |
| US10959933B1 (en) | 2020-06-01 | 2021-03-30 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
| CN111632049A (zh) * | 2020-06-09 | 2020-09-08 | 西北农林科技大学 | 一种通过综合矫正细胞活性氧簇代谢紊乱以缓解睾丸衰老损伤的复合配方 |
| WO2022047182A1 (en) * | 2020-08-28 | 2022-03-03 | University Of Washington | High dose nicotinamide adenine dinucleotide (nad) precursor regimens for reduction of inflammation in human patients with preexisting inflammation |
| JP7761652B2 (ja) * | 2021-01-19 | 2025-10-28 | バイオシント アクチェンゲゼルシャフト | 塩メタセシスによるニコチンアミドリボフラノシド塩の製造方法、そのトシレート塩の結晶形態及びそのクロリド：ヨージド塩の共結晶化した形態 |
| JP2024517463A (ja) * | 2021-05-04 | 2024-04-22 | ソヴィダ ソリューションズ リミテッド | ニコチンアミドアデニンジヌクレオチド（ｎａｄ）組成物、それらの製造方法、及びそれらの使用方法 |
| CN114129509B (zh) * | 2021-12-03 | 2023-12-01 | 药酚享科技(北京)有限公司 | 一种保湿性nmn亲水凝胶剂及其制备方法 |
| CN116621898A (zh) * | 2022-04-13 | 2023-08-22 | 深圳市迪克曼科技开发有限公司 | 烟酰胺核糖的有机酸盐及其结晶形态、制备方法与用途 |
| KR102784901B1 (ko) * | 2022-06-23 | 2025-03-21 | 제너럴바이오(주) | Nr, nmn 및 nad를 함유한 피부 주름 개선용 화장료 조성물 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3780257B2 (ja) * | 2001-02-22 | 2006-05-31 | ユニリーバー・ナームローゼ・ベンノートシヤープ | 油及び脂肪を抑制する皮膚用組成物 |
| US7977049B2 (en) | 2002-08-09 | 2011-07-12 | President And Fellows Of Harvard College | Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms |
| EP1723227A4 (en) | 2004-02-10 | 2007-09-19 | Dartmouth College | NICOTINAMIDRIBOSIDE KINASE COMPOSITIONS AND METHOD FOR THEIR USE |
| AU2005257883A1 (en) | 2004-06-04 | 2006-01-05 | Washington University | Methods and compositions for treating neuropathies |
| EP2805719A1 (en) | 2005-03-30 | 2014-11-26 | Glaxosmithkline LLC | Nicotinamide riboside and analogues thereof |
| WO2006138418A2 (en) | 2005-06-14 | 2006-12-28 | President And Fellows Of Harvard College | Improvement of cognitive performance with sirtuin activators |
| CN101257897A (zh) * | 2005-07-07 | 2008-09-03 | 西特里斯药业公司 | 用于治疗或预防肥胖、胰岛素抵抗障碍和线粒体相关障碍的方法和相关组合物 |
| CA2613141A1 (en) * | 2005-07-07 | 2007-01-18 | Sirtris Pharmaceuticals, Inc. | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
| DK1957086T3 (en) * | 2005-11-18 | 2018-06-06 | Cornell Res Foundation Inc | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE |
| JP2010520897A (ja) * | 2007-03-12 | 2010-06-17 | ディーエスエム アイピー アセッツ ビー．ブイ． | 化粧品組成物 |
| US20090069444A1 (en) | 2007-09-07 | 2009-03-12 | The United States Of America, As Represented By Th E Secretary Of Agriculture | Method to Ameliorate Oxidative Stress and Improve Working Memory Via Pterostilbene Administration |
| MX2012007873A (es) * | 2010-01-06 | 2012-07-25 | Yakult Honsha Kk | Promotor de reparacion del daño de acido desoxirribonucleico para aplicacion oral e inhibidor de la actividad de elastasa para apalicacion oral. |
-
2014
- 2014-10-30 CN CN201480071722.4A patent/CN105873937A/zh active Pending
- 2014-10-30 KR KR1020217026414A patent/KR20210107895A/ko not_active Ceased
- 2014-10-30 AU AU2014342185A patent/AU2014342185B2/en active Active
- 2014-10-30 ES ES14857903T patent/ES2925879T3/es active Active
- 2014-10-30 NZ NZ719328A patent/NZ719328A/en unknown
- 2014-10-30 CA CA2928656A patent/CA2928656C/en active Active
- 2014-10-30 KR KR1020227022241A patent/KR20220098049A/ko not_active Ceased
- 2014-10-30 EP EP14857903.0A patent/EP3063163B1/en active Active
- 2014-10-30 WO PCT/US2014/063260 patent/WO2015066382A1/en not_active Ceased
- 2014-10-30 MX MX2016005574A patent/MX385305B/es unknown
- 2014-10-30 CN CN201910027571.7A patent/CN109985056A/zh active Pending
- 2014-10-30 JP JP2016526337A patent/JP6509844B2/ja active Active
- 2014-10-30 US US15/033,285 patent/US10688118B2/en active Active
- 2014-10-30 KR KR1020167014302A patent/KR20160067195A/ko not_active Ceased
- 2014-10-30 MX MX2021009652A patent/MX394291B/es unknown
-
2016
- 2016-05-16 ZA ZA2016/03314A patent/ZA201603314B/en unknown
-
2020
- 2020-06-03 US US16/891,824 patent/US11033568B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2014342185B2 (en) | 2019-01-03 |
| WO2015066382A1 (en) | 2015-05-07 |
| KR20220098049A (ko) | 2022-07-08 |
| US20200289536A1 (en) | 2020-09-17 |
| MX2021009652A (es) | 2022-07-26 |
| CN105873937A (zh) | 2016-08-17 |
| CA2928656C (en) | 2020-07-28 |
| CN109985056A (zh) | 2019-07-09 |
| US20160250241A1 (en) | 2016-09-01 |
| US10688118B2 (en) | 2020-06-23 |
| JP2016538271A (ja) | 2016-12-08 |
| JP6509844B2 (ja) | 2019-05-08 |
| CA2928656A1 (en) | 2015-05-07 |
| NZ719328A (en) | 2022-04-29 |
| ES2925879T3 (es) | 2022-10-20 |
| ZA201603314B (en) | 2017-09-27 |
| KR20160067195A (ko) | 2016-06-13 |
| EP3063163B1 (en) | 2022-08-10 |
| EP3063163A1 (en) | 2016-09-07 |
| US11033568B2 (en) | 2021-06-15 |
| MX394291B (es) | 2025-03-24 |
| KR20210107895A (ko) | 2021-09-01 |
| EP3063163A4 (en) | 2017-05-10 |
| MX2016005574A (es) | 2016-12-09 |
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