MX384989B - Uso de un agonista del receptor x retinoide (rxr) en combinación con una hormona tiroidea para el tratamiento de esclerosis múltiple. - Google Patents

Uso de un agonista del receptor x retinoide (rxr) en combinación con una hormona tiroidea para el tratamiento de esclerosis múltiple.

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Publication number
MX384989B
MX384989B MX2019005503A MX2019005503A MX384989B MX 384989 B MX384989 B MX 384989B MX 2019005503 A MX2019005503 A MX 2019005503A MX 2019005503 A MX2019005503 A MX 2019005503A MX 384989 B MX384989 B MX 384989B
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Mexico
Prior art keywords
combination
rxr
agonist
retinoid
receptor
Prior art date
Application number
MX2019005503A
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English (en)
Other versions
MX2019005503A (es
Inventor
Martin E Sanders
Roshantha A Chandraratna
Original Assignee
Io Therapeutics Inc
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Publication date
Application filed by Io Therapeutics Inc filed Critical Io Therapeutics Inc
Publication of MX2019005503A publication Critical patent/MX2019005503A/es
Publication of MX384989B publication Critical patent/MX384989B/es

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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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Abstract

En la presente se describen métodos para tratar una enfermedad con una combinación de un agonista de RXR y una hormona tiroidea.
MX2019005503A 2015-10-31 2016-10-31 Uso de un agonista del receptor x retinoide (rxr) en combinación con una hormona tiroidea para el tratamiento de esclerosis múltiple. MX384989B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562249216P 2015-10-31 2015-10-31
PCT/US2016/059770 WO2017075607A1 (en) 2015-10-31 2016-10-31 Treatment of nervous system disorders using combinations of pxr agonists and thyroid hormones

Publications (2)

Publication Number Publication Date
MX2019005503A MX2019005503A (es) 2019-08-21
MX384989B true MX384989B (es) 2025-03-14

Family

ID=58630939

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2019005503A MX384989B (es) 2015-10-31 2016-10-31 Uso de un agonista del receptor x retinoide (rxr) en combinación con una hormona tiroidea para el tratamiento de esclerosis múltiple.
MX2018005144A MX364892B (es) 2015-10-31 2016-10-31 Tratamiento de trastornos del sistema nervioso utilizando combinaciones de agonistas de rxr y hormonas tiroideas.
MX2021009133A MX2021009133A (es) 2015-10-31 2018-04-25 Uso de un agonista del receptor x retinoide (rxr) en combinacion con una hormona tiroidea para el tratamiento de esclerosis multiple.

Family Applications After (2)

Application Number Title Priority Date Filing Date
MX2018005144A MX364892B (es) 2015-10-31 2016-10-31 Tratamiento de trastornos del sistema nervioso utilizando combinaciones de agonistas de rxr y hormonas tiroideas.
MX2021009133A MX2021009133A (es) 2015-10-31 2018-04-25 Uso de un agonista del receptor x retinoide (rxr) en combinacion con una hormona tiroidea para el tratamiento de esclerosis multiple.

Country Status (17)

Country Link
US (19) US9877941B2 (es)
EP (1) EP3368080B8 (es)
JP (4) JP6823071B2 (es)
KR (3) KR102489706B1 (es)
CN (4) CN116077626A (es)
AU (1) AU2016344018B2 (es)
CA (1) CA3003734C (es)
DK (1) DK3368080T3 (es)
ES (1) ES2941769T3 (es)
HK (1) HK1255075A1 (es)
IL (1) IL259025B (es)
MX (3) MX384989B (es)
NZ (1) NZ741393A (es)
PL (1) PL3368080T3 (es)
SG (1) SG11201803592XA (es)
WO (1) WO2017075607A1 (es)
ZA (1) ZA201802749B (es)

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