MX378261B - Formas de dosificación sólidas de liberación prolongada antieméticas. - Google Patents
Formas de dosificación sólidas de liberación prolongada antieméticas.Info
- Publication number
- MX378261B MX378261B MX2015012970A MX2015012970A MX378261B MX 378261 B MX378261 B MX 378261B MX 2015012970 A MX2015012970 A MX 2015012970A MX 2015012970 A MX2015012970 A MX 2015012970A MX 378261 B MX378261 B MX 378261B
- Authority
- MX
- Mexico
- Prior art keywords
- amount
- antiemetic
- drug
- dosage forms
- solid dosage
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se describe una forma de dosificación oral sólida que incluye un núcleo que comprende una matriz polimérica no iónica, una primera cantidad de un primer fármaco antiemético o una sal farmacéuticamente aceptable del mismo dispersa dentro de la matriz, y una sal dispersa dentro de la matriz; un primer recubrimiento de sello de una matriz polimérica no iónica que rodea el núcleo; y una capa de fármaco de liberación inmediata que rodea el primer recubrimiento de sello, donde la capa de fármaco de liberación inmediata comprende un polímero no iónico y una segunda cantidad de un segundo fármaco antiemético o de una sal farmacéuticamente aceptable del mismo dispersa en el mismo, donde la capa de fármaco se diseña suficientemente para liberar la segunda cantidad de fármaco antiemético durante por lo menos 1 hora, donde la forma de dosificación oral sólida se diseña suficientemente para liberar la primera cantidad del primera fármaco antiemético y la segunda cantidad del segundo fármaco antiemético durante un período mínimo de 16 horas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361782395P | 2013-03-14 | 2013-03-14 | |
| PCT/IB2014/001633 WO2014181195A2 (en) | 2013-03-14 | 2014-03-14 | Antiemetic extended release solid dosage forms |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015012970A MX2015012970A (es) | 2016-04-11 |
| MX378261B true MX378261B (es) | 2025-03-10 |
Family
ID=51528070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015012970A MX378261B (es) | 2013-03-14 | 2014-03-14 | Formas de dosificación sólidas de liberación prolongada antieméticas. |
Country Status (19)
| Country | Link |
|---|---|
| US (5) | US9636305B2 (es) |
| EP (1) | EP2983664B1 (es) |
| JP (1) | JP6282676B2 (es) |
| KR (1) | KR102270521B1 (es) |
| CN (2) | CN105530935A (es) |
| AU (1) | AU2014264342B2 (es) |
| BR (1) | BR112015022398B1 (es) |
| CA (1) | CA2905553C (es) |
| CL (1) | CL2015002666A1 (es) |
| ES (1) | ES2946985T3 (es) |
| HK (1) | HK1223012A1 (es) |
| IL (1) | IL241580B (es) |
| MX (1) | MX378261B (es) |
| NZ (1) | NZ712159A (es) |
| PH (1) | PH12015502093B1 (es) |
| RU (1) | RU2679448C2 (es) |
| SG (1) | SG11201507450TA (es) |
| WO (2) | WO2014181195A2 (es) |
| ZA (1) | ZA201506961B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2679448C2 (ru) | 2013-03-14 | 2019-02-11 | Редхилл Байофарма Лтд. | Твердые лекарственные формы, обладающие противорвотным действием, с замедленным высвобождением |
| MX373002B (es) | 2014-03-11 | 2020-04-30 | Redhill Biopharma Ltd | Formas de dosificacion sólida de liberación extendida de ondansetrón para tratar bien sea síntomas de náusea, vómito o diarrea |
| CA2910865C (en) | 2014-07-15 | 2016-11-29 | Isa Odidi | Compositions and methods for reducing overdose |
| KR102300335B1 (ko) * | 2018-10-19 | 2021-09-10 | 주식회사 삼양홀딩스 | 아프레피탄트의 경구용 조성물 |
| WO2024096892A1 (en) * | 2022-11-03 | 2024-05-10 | Lumos Pharma, Inc. | Compactable oral formulations of ibutamoren |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4720353A (en) | 1987-04-14 | 1988-01-19 | Richardson-Vicks Inc. | Stable pharmaceutical w/o emulsion composition |
| US6090411A (en) | 1998-03-09 | 2000-07-18 | Temple University | Monolithic tablet for controlled drug release |
| US6733789B1 (en) * | 1999-01-21 | 2004-05-11 | Biovail Laboratories, Inc. | Multiparticulate bisoprolol formulation |
| JP2003516345A (ja) | 1999-12-09 | 2003-05-13 | アルザ・コーポレーション | 抗ウイルス剤 |
| US6936275B2 (en) | 1999-12-20 | 2005-08-30 | Scolr, Inc. | Amino acid modulated extended release dosage form |
| WO2003024427A1 (en) | 1999-12-20 | 2003-03-27 | Temple University Of The Commonwealth System Of Higher Education | Tableted oral extended release dosage form |
| US20020044962A1 (en) * | 2000-06-06 | 2002-04-18 | Cherukuri S. Rao | Encapsulation products for controlled or extended release |
| US6500457B1 (en) | 2000-08-14 | 2002-12-31 | Peirce Management, Llc | Oral pharmaceutical dosage forms for pulsatile delivery of an antiarrhythmic agent |
| US20020172712A1 (en) * | 2001-03-19 | 2002-11-21 | Alan Drizen | Antiemetic, anti-motion sustained release drug delivery system |
| GB0119012D0 (en) | 2001-08-03 | 2001-09-26 | Strakan Group Plc | Transdermal delivery of drugs |
| GB0129489D0 (en) * | 2001-12-10 | 2002-01-30 | Quadrant Healthcare Uk Ltd | Sustained-release compositions |
| US20050131045A1 (en) * | 2002-04-30 | 2005-06-16 | Judith Aronhime | Novel crystal forms of ondansetron, processes for their preparation, pharmaceutical, compositions containing the novel forms and methods for treating nausea using them |
| US7704527B2 (en) * | 2002-10-25 | 2010-04-27 | Collegium Pharmaceutical, Inc. | Modified release compositions of milnacipran |
| AU2004204827B2 (en) | 2003-01-13 | 2006-06-29 | Dynogen Pharmaceuticals, Inc. | Method of treating nausea, vomiting, retching or any combination thereof |
| JP4674162B2 (ja) | 2003-11-14 | 2011-04-20 | 千寿製薬株式会社 | アミノグリコシド系抗生物質およびブロムフェナクを含有する水溶液製剤 |
| RU2382637C2 (ru) * | 2004-04-30 | 2010-02-27 | Астеллас Фарма Инк. | Фармацевтическая композиция для перорального введения в форме частиц с рассчитанным временем высвобождения и быстро распадающиеся таблетки, содержащие указанную композицию |
| CN101132777A (zh) * | 2004-12-20 | 2008-02-27 | 科利吉姆制药公司 | 用于睡眠障碍的药物组合物 |
| ATE489079T1 (de) * | 2005-12-29 | 2010-12-15 | Osmotica Kereskedelmi Es Szolgaltata Kft | Mehrschichtige tablette mit dreifacher freisetzungskombination |
| US20070190141A1 (en) * | 2006-02-16 | 2007-08-16 | Aaron Dely | Extended release opiate composition |
| US20080004260A1 (en) * | 2006-06-29 | 2008-01-03 | Transcept Pharmaceuticals, Inc. | Compositions of 5-HT3 antagonists and dopamine D2 antagonists for treatment of dopamine-associated chronic conditions |
| PL2051704T3 (pl) | 2006-08-18 | 2012-09-28 | Evonik Roehm Gmbh | Kompozycja farmaceutyczna o kontrolowanym dostarczaniu substancji aktywnej o dobrej rozpuszczalności |
| CN100584319C (zh) | 2006-10-16 | 2010-01-27 | 北京科信必成医药科技发展有限公司 | 群孔释放渗透泵控释片及其制备方法 |
| BRPI0718428A2 (pt) * | 2006-10-25 | 2013-11-12 | Mcneil Ppc Inc | Composição de ibuprofeno |
| GB0624087D0 (en) | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril combination salt |
| JP2010514679A (ja) * | 2006-12-22 | 2010-05-06 | スリーエム イノベイティブ プロパティズ カンパニー | 制御放出組成物及び方法 |
| WO2009118763A1 (en) | 2008-03-28 | 2009-10-01 | Panacea Biotec Limited | Multilayered pharmaceutical compositions and processes thereof |
| US20100196291A1 (en) * | 2009-01-30 | 2010-08-05 | Laurence Halimi | Personal care sunscreen compositions having reduced eye irritation |
| EP2403487A2 (en) * | 2009-03-04 | 2012-01-11 | Fdc Limited | Oral controlled release dosage forms for water soluble drugs |
| US20110003005A1 (en) * | 2009-07-06 | 2011-01-06 | Gopi Venkatesh | Methods of Treating PDNV and PONV with Extended Release Ondansetron Compositions |
| RU2427389C2 (ru) * | 2009-10-09 | 2011-08-27 | Александр Владимирович Диковский | Фармацевтическая композиция для профилактики и лечения инфекционных и неинфекционных диарей |
| WO2011066289A1 (en) * | 2009-11-30 | 2011-06-03 | Eurand, Inc. | Ondansetron orally disintegrating tablet compositions for prevention of nausea and vomiting |
| EP2515882A2 (en) * | 2009-12-22 | 2012-10-31 | Abbot Healthcare Private Limited | Controlled release pharmaceutical composition |
| CA2784587A1 (en) | 2009-12-28 | 2011-07-28 | Monosol Rx, Llc | Orally administrable film dosage forms containing ondansetron |
| JP2013536832A (ja) | 2010-08-30 | 2013-09-26 | ルピン・リミテッド | ミルナシプランの制御放出医薬組成物 |
| US20120128730A1 (en) * | 2010-11-23 | 2012-05-24 | Nipun Davar | Compositions and methods for once-daily treatment of obsessive compulsive disorder with ondansetron |
| RU2679448C2 (ru) | 2013-03-14 | 2019-02-11 | Редхилл Байофарма Лтд. | Твердые лекарственные формы, обладающие противорвотным действием, с замедленным высвобождением |
-
2014
- 2014-03-14 RU RU2015143993A patent/RU2679448C2/ru active
- 2014-03-14 ES ES14795266T patent/ES2946985T3/es active Active
- 2014-03-14 WO PCT/IB2014/001633 patent/WO2014181195A2/en not_active Ceased
- 2014-03-14 AU AU2014264342A patent/AU2014264342B2/en active Active
- 2014-03-14 NZ NZ712159A patent/NZ712159A/en not_active IP Right Cessation
- 2014-03-14 CN CN201480024401.9A patent/CN105530935A/zh active Pending
- 2014-03-14 SG SG11201507450TA patent/SG11201507450TA/en unknown
- 2014-03-14 HK HK16111017.8A patent/HK1223012A1/zh unknown
- 2014-03-14 MX MX2015012970A patent/MX378261B/es unknown
- 2014-03-14 EP EP14795266.7A patent/EP2983664B1/en active Active
- 2014-03-14 KR KR1020157028825A patent/KR102270521B1/ko active Active
- 2014-03-14 BR BR112015022398-2A patent/BR112015022398B1/pt active IP Right Grant
- 2014-03-14 WO PCT/IB2014/001589 patent/WO2014184662A2/en not_active Ceased
- 2014-03-14 JP JP2015562425A patent/JP6282676B2/ja active Active
- 2014-03-14 CN CN202011222247.XA patent/CN112274489A/zh active Pending
- 2014-03-14 CA CA2905553A patent/CA2905553C/en active Active
- 2014-03-14 US US14/212,694 patent/US9636305B2/en active Active
- 2014-03-14 US US14/212,954 patent/US20140271851A1/en not_active Abandoned
-
2015
- 2015-09-10 IL IL241580A patent/IL241580B/en active IP Right Grant
- 2015-09-14 PH PH12015502093A patent/PH12015502093B1/en unknown
- 2015-09-14 CL CL2015002666A patent/CL2015002666A1/es unknown
- 2015-09-18 ZA ZA2015/06961A patent/ZA201506961B/en unknown
-
2017
- 2017-03-22 US US15/466,214 patent/US20170189340A1/en not_active Abandoned
- 2017-08-16 US US15/678,386 patent/US20180028452A1/en not_active Abandoned
-
2020
- 2020-07-01 US US16/918,538 patent/US20200330392A1/en not_active Abandoned
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