MX376743B - Síntesis de lactonas de ácido resorcílico útiles como agentes terapéuticos - Google Patents

Síntesis de lactonas de ácido resorcílico útiles como agentes terapéuticos

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Publication number
MX376743B
MX376743B MX2017005952A MX2017005952A MX376743B MX 376743 B MX376743 B MX 376743B MX 2017005952 A MX2017005952 A MX 2017005952A MX 2017005952 A MX2017005952 A MX 2017005952A MX 376743 B MX376743 B MX 376743B
Authority
MX
Mexico
Prior art keywords
synthesis
therapeutic agents
acid lactones
resorcylic acid
lactones useful
Prior art date
Application number
MX2017005952A
Other languages
English (en)
Inventor
Martin Karplus
Nicolas Winssinger
Sofia Barluenga
Original Assignee
Univ Strasbourg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Strasbourg filed Critical Univ Strasbourg
Publication of MX376743B publication Critical patent/MX376743B/es

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    • A61K31/365—Lactones
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    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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  • Oncology (AREA)
  • Reproductive Health (AREA)

Abstract

Se describen compuestos macrocíclicos de las fórmulas I, I', II, II', III, III', IV, y V, que son análogos de las lactonas de ácido resorcíclico de pochonina, composiciones farmacéuticas que comprenden los compuestos, y métodos y usos que comprenden los compuestos para el tratamiento de enfermedades mediadas por cinasas y Proteína de Choque Térmico 90 HSP90.
MX2017005952A 2008-01-15 2009-01-15 Síntesis de lactonas de ácido resorcílico útiles como agentes terapéuticos MX376743B (es)

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CN119424412A (zh) * 2024-12-04 2025-02-14 中国药科大学 以prdx1作为药物靶标的天然抑制剂在制备抗乳腺癌药物中的应用

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MX2010007755A (es) 2010-12-21
AU2009206097A1 (en) 2009-07-23
JP2015110624A (ja) 2015-06-18
WO2009091921A1 (en) 2009-07-23
EP2242359A4 (en) 2011-11-09
IL207049A (en) 2015-01-29
KR20160112016A (ko) 2016-09-27
BRPI0905687A2 (pt) 2015-07-07
CA2755876A1 (en) 2009-07-23
KR101835252B1 (ko) 2018-03-06
KR20160017105A (ko) 2016-02-15
KR101835253B1 (ko) 2018-03-06
US10239856B2 (en) 2019-03-26
JP6159350B2 (ja) 2017-07-05
AU2009206097B2 (en) 2014-08-14
KR20160112015A (ko) 2016-09-27
ES2587390T3 (es) 2016-10-24
EP2242359B1 (en) 2016-06-01
IL207049A0 (en) 2010-12-30
CA2755876C (en) 2017-04-18
JP2011510017A (ja) 2011-03-31
US20160075677A1 (en) 2016-03-17
RU2010133979A (ru) 2012-02-27
CN101990399B (zh) 2016-05-04
CN101990399A (zh) 2011-03-23
US20190359585A1 (en) 2019-11-28
EP2242359A1 (en) 2010-10-27
KR20110003468A (ko) 2011-01-12
US9051302B2 (en) 2015-06-09
RU2534527C2 (ru) 2014-11-27
US20110217335A1 (en) 2011-09-08
BRPI0905687A8 (pt) 2019-05-21

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