MX374652B - Ensayos para detectar la presencia o la cantidad de un anticuerpo antifármaco. - Google Patents

Ensayos para detectar la presencia o la cantidad de un anticuerpo antifármaco.

Info

Publication number
MX374652B
MX374652B MX2016010413A MX2016010413A MX374652B MX 374652 B MX374652 B MX 374652B MX 2016010413 A MX2016010413 A MX 2016010413A MX 2016010413 A MX2016010413 A MX 2016010413A MX 374652 B MX374652 B MX 374652B
Authority
MX
Mexico
Prior art keywords
tests
detect
antidrug antibody
antidrug
antibody
Prior art date
Application number
MX2016010413A
Other languages
English (en)
Other versions
MX2016010413A (es
Inventor
Jad Zoghbi
Ryan Grabert
Susan Richards
Valerie Theobald
Yuanxin Xu
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of MX2016010413A publication Critical patent/MX2016010413A/es
Publication of MX374652B publication Critical patent/MX374652B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2430/00—Assays, e.g. immunoassays or enzyme assays, involving synthetic organic compounds as analytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a métodos y kits para detectar anticuerpos (por ejemplo, anticuerpos antifármaco). Estos métodos y kits permiten la detección, por ejemplo, de anticuerpos antifármaco en fluidos corporales humanos, tales como sangre, plasma y suero.
MX2016010413A 2014-02-11 2015-02-11 Ensayos para detectar la presencia o la cantidad de un anticuerpo antifármaco. MX374652B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461938556P 2014-02-11 2014-02-11
PCT/US2015/015442 WO2015123315A1 (en) 2014-02-11 2015-02-11 Assays for detecting the presence or amount of an anti-drug antibody

Publications (2)

Publication Number Publication Date
MX2016010413A MX2016010413A (es) 2016-11-30
MX374652B true MX374652B (es) 2025-03-06

Family

ID=52684652

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016010413A MX374652B (es) 2014-02-11 2015-02-11 Ensayos para detectar la presencia o la cantidad de un anticuerpo antifármaco.
MX2020009021A MX2020009021A (es) 2014-02-11 2016-08-10 Ensayos para detectar la presencia o la cantidad de un anticuerpo antifarmaco.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2020009021A MX2020009021A (es) 2014-02-11 2016-08-10 Ensayos para detectar la presencia o la cantidad de un anticuerpo antifarmaco.

Country Status (19)

Country Link
US (4) US9759732B2 (es)
EP (5) EP4137816B1 (es)
CN (1) CN106164670B (es)
AU (2) AU2015217261B2 (es)
CA (1) CA2939080A1 (es)
CY (1) CY1121341T1 (es)
DK (1) DK3105592T3 (es)
ES (1) ES2705403T3 (es)
HR (1) HRP20190026T1 (es)
HU (1) HUE041669T2 (es)
LT (1) LT3105592T (es)
MX (2) MX374652B (es)
PL (1) PL3105592T3 (es)
PT (1) PT3105592T (es)
RS (1) RS58212B1 (es)
SG (2) SG11201606291VA (es)
SI (1) SI3105592T1 (es)
TR (1) TR201900160T4 (es)
WO (1) WO2015123315A1 (es)

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CN109358192B (zh) * 2018-02-08 2020-05-12 中国科学院上海药物研究所 一种去除抗药抗体检测样品中游离药物的装置和方法、该装置的制备方法及应用
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WO2020214795A1 (en) * 2019-04-16 2020-10-22 Laboratory Corporation Of America Holdings Methods and systems for detecting antibodies by surface plasmon resonance
KR102695013B1 (ko) 2019-04-24 2024-08-13 삼성전자주식회사 펠리클 조립체의 제조 방법 및 포토마스크 조립체의 제조 방법
CN111982615A (zh) * 2019-05-23 2020-11-24 百奥泰生物制药股份有限公司 一种用于解离药物/ada复合物的解离液及其应用
CN112285351A (zh) * 2019-07-22 2021-01-29 上海益诺思生物技术股份有限公司 一种抗IgE单抗的ELISA检测方法
CA3148161A1 (en) * 2019-09-05 2021-03-11 Adverum Biotechnologies Anti-drug antibody assay
CN111171141A (zh) * 2020-01-20 2020-05-19 苏州药明康德新药开发有限公司 聚乙二醇在临床前安全性评价中的应用
CN111024958B (zh) * 2020-03-11 2020-06-23 同昕生物技术（北京）有限公司 用于检测单抗药物和抗单抗药物抗体的试剂及其应用
BR112022021039A2 (pt) * 2020-05-01 2022-12-06 Regeneron Pharma Ensaio de anticorpo neutralizante para proteínas terapêuticas
JP7478040B2 (ja) * 2020-06-25 2024-05-02 シスメックス株式会社 Ａβペプチドの測定方法及びその方法に用いられる試薬組成物
CN116261662B (zh) * 2020-10-14 2024-05-31 天境生物科技(上海)有限公司 用于减轻输血前测定中治疗性抗cd47抗体的干扰的方法
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JP7062803B1 (ja) * 2021-03-31 2022-05-06 積水メディカル株式会社 抗薬物抗体測定方法
EP4448570A1 (en) 2021-12-14 2024-10-23 CDR-Life AG Dual mhc-targeting t cell engager
CN114047343B (zh) * 2022-01-13 2022-05-31 美迪西普亚医药科技(上海)有限公司 双耐受型抗IgE单抗药物的免疫原性分析试剂盒及其使用方法和应用
TW202426498A (zh) 2022-09-09 2024-07-01 德商拜耳廠股份有限公司 Ccr8抗體之醫藥用途及給藥計劃
CN120202015A (zh) 2022-09-14 2025-06-24 Cdr-生物科技股份有限公司 Mage-a4肽双重t细胞衔接子
US20250383363A1 (en) * 2022-09-23 2025-12-18 Merck Sharp & Dohme Llc Neutralization antibody assay method
CN115561355B (zh) * 2022-09-26 2024-04-30 重庆迪纳利医药科技有限责任公司 羧肽酶g2的中和抗体检测方法以及基于lc-ms/ms的检测系统
CN116699147A (zh) * 2023-08-04 2023-09-05 军科正源（北京）药物研究有限责任公司 检测总IgE含量的方法以及相关试剂盒
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Also Published As

Publication number Publication date
CY1121341T1 (el) 2020-05-29
EP3667321A1 (en) 2020-06-17
AU2015217261B2 (en) 2020-08-27
EP3105592B1 (en) 2018-10-17
RS58212B1 (sr) 2019-03-29
US20180088140A1 (en) 2018-03-29
CA2939080A1 (en) 2015-08-20
ES2705403T3 (es) 2019-03-25
LT3105592T (lt) 2019-01-25
US20150226758A1 (en) 2015-08-13
MX2016010413A (es) 2016-11-30
US11215623B2 (en) 2022-01-04
DK3105592T3 (en) 2019-02-04
US20240288454A1 (en) 2024-08-29
EP4137816A1 (en) 2023-02-22
EP4582812A3 (en) 2025-10-22
SG11201606291VA (en) 2016-08-30
US20220187327A1 (en) 2022-06-16
PL3105592T3 (pl) 2019-04-30
EP3422001B1 (en) 2020-03-25
EP3422001A1 (en) 2019-01-02
EP4582812A2 (en) 2025-07-09
SI3105592T1 (sl) 2019-02-28
PT3105592T (pt) 2019-01-23
TR201900160T4 (tr) 2019-02-21
CN106164670B (zh) 2019-06-14
US9759732B2 (en) 2017-09-12
AU2015217261A1 (en) 2016-09-08
EP3667321B1 (en) 2022-07-27
EP4137816B1 (en) 2025-03-19
AU2020264316A1 (en) 2020-11-26
SG10201906750XA (en) 2019-09-27
HRP20190026T1 (hr) 2019-02-22
US11927596B2 (en) 2024-03-12
EP3105592A1 (en) 2016-12-21
WO2015123315A1 (en) 2015-08-20
MX2020009021A (es) 2020-10-12
HUE041669T2 (hu) 2019-05-28
CN106164670A (zh) 2016-11-23

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