MX374652B - Ensayos para detectar la presencia o la cantidad de un anticuerpo antifármaco. - Google Patents

Ensayos para detectar la presencia o la cantidad de un anticuerpo antifármaco.

Info

Publication number
MX374652B
MX374652B MX2016010413A MX2016010413A MX374652B MX 374652 B MX374652 B MX 374652B MX 2016010413 A MX2016010413 A MX 2016010413A MX 2016010413 A MX2016010413 A MX 2016010413A MX 374652 B MX374652 B MX 374652B
Authority
MX
Mexico
Prior art keywords
tests
detect
antidrug antibody
antidrug
antibody
Prior art date
Application number
MX2016010413A
Other languages
English (en)
Other versions
MX2016010413A (es
Inventor
Jad Zoghbi
Ryan Grabert
Susan Richards
Valerie Theobald
Yuanxin Xu
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of MX2016010413A publication Critical patent/MX2016010413A/es
Publication of MX374652B publication Critical patent/MX374652B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2430/00—Assays, e.g. immunoassays or enzyme assays, involving synthetic organic compounds as analytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a métodos y kits para detectar anticuerpos (por ejemplo, anticuerpos antifármaco). Estos métodos y kits permiten la detección, por ejemplo, de anticuerpos antifármaco en fluidos corporales humanos, tales como sangre, plasma y suero.
MX2016010413A 2014-02-11 2015-02-11 Ensayos para detectar la presencia o la cantidad de un anticuerpo antifármaco. MX374652B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461938556P 2014-02-11 2014-02-11
PCT/US2015/015442 WO2015123315A1 (en) 2014-02-11 2015-02-11 Assays for detecting the presence or amount of an anti-drug antibody

Publications (2)

Publication Number Publication Date
MX2016010413A MX2016010413A (es) 2016-11-30
MX374652B true MX374652B (es) 2025-03-06

Family

ID=52684652

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016010413A MX374652B (es) 2014-02-11 2015-02-11 Ensayos para detectar la presencia o la cantidad de un anticuerpo antifármaco.
MX2020009021A MX2020009021A (es) 2014-02-11 2016-08-10 Ensayos para detectar la presencia o la cantidad de un anticuerpo antifarmaco.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2020009021A MX2020009021A (es) 2014-02-11 2016-08-10 Ensayos para detectar la presencia o la cantidad de un anticuerpo antifarmaco.

Country Status (19)

Country Link
US (4) US9759732B2 (es)
EP (5) EP4137816B1 (es)
CN (1) CN106164670B (es)
AU (2) AU2015217261B2 (es)
CA (1) CA2939080A1 (es)
CY (1) CY1121341T1 (es)
DK (1) DK3105592T3 (es)
ES (1) ES2705403T3 (es)
HR (1) HRP20190026T1 (es)
HU (1) HUE041669T2 (es)
LT (1) LT3105592T (es)
MX (2) MX374652B (es)
PL (1) PL3105592T3 (es)
PT (1) PT3105592T (es)
RS (1) RS58212B1 (es)
SG (2) SG11201606291VA (es)
SI (1) SI3105592T1 (es)
TR (1) TR201900160T4 (es)
WO (1) WO2015123315A1 (es)

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JP7541534B2 (ja) * 2019-05-13 2024-08-28 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 改善された競合的リガンド結合アッセイ
CN111982615A (zh) * 2019-05-23 2020-11-24 百奥泰生物制药股份有限公司 一种用于解离药物/ada复合物的解离液及其应用
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CN115561355B (zh) * 2022-09-26 2024-04-30 重庆迪纳利医药科技有限责任公司 羧肽酶g2的中和抗体检测方法以及基于lc-ms/ms的检测系统
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Also Published As

Publication number Publication date
EP4582812A2 (en) 2025-07-09
SG11201606291VA (en) 2016-08-30
EP3667321B1 (en) 2022-07-27
EP4137816B1 (en) 2025-03-19
HRP20190026T1 (hr) 2019-02-22
AU2015217261A1 (en) 2016-09-08
EP4137816A1 (en) 2023-02-22
AU2015217261B2 (en) 2020-08-27
DK3105592T3 (en) 2019-02-04
PT3105592T (pt) 2019-01-23
EP3422001A1 (en) 2019-01-02
US9759732B2 (en) 2017-09-12
TR201900160T4 (tr) 2019-02-21
ES2705403T3 (es) 2019-03-25
AU2020264316A1 (en) 2020-11-26
WO2015123315A1 (en) 2015-08-20
US12566186B2 (en) 2026-03-03
SI3105592T1 (sl) 2019-02-28
CA2939080A1 (en) 2015-08-20
US11927596B2 (en) 2024-03-12
CY1121341T1 (el) 2020-05-29
EP3105592A1 (en) 2016-12-21
US20150226758A1 (en) 2015-08-13
PL3105592T3 (pl) 2019-04-30
US20180088140A1 (en) 2018-03-29
MX2016010413A (es) 2016-11-30
US11215623B2 (en) 2022-01-04
EP3422001B1 (en) 2020-03-25
CN106164670A (zh) 2016-11-23
EP3105592B1 (en) 2018-10-17
MX2020009021A (es) 2020-10-12
US20240288454A1 (en) 2024-08-29
CN106164670B (zh) 2019-06-14
EP3667321A1 (en) 2020-06-17
SG10201906750XA (en) 2019-09-27
EP4582812A3 (en) 2025-10-22
RS58212B1 (sr) 2019-03-29
US20220187327A1 (en) 2022-06-16
LT3105592T (lt) 2019-01-25
HUE041669T2 (hu) 2019-05-28

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