MX373312B - Proceso para la preparación de ácidos 4-alcoxi-3-hidroxipicolínicos. - Google Patents

Proceso para la preparación de ácidos 4-alcoxi-3-hidroxipicolínicos.

Info

Publication number
MX373312B
MX373312B MX2016017127A MX2016017127A MX373312B MX 373312 B MX373312 B MX 373312B MX 2016017127 A MX2016017127 A MX 2016017127A MX 2016017127 A MX2016017127 A MX 2016017127A MX 373312 B MX373312 B MX 373312B
Authority
MX
Mexico
Prior art keywords
alkoxy
preparation
hydroxypicolinic acids
hydroxypicolinic
acids
Prior art date
Application number
MX2016017127A
Other languages
English (en)
Other versions
MX2016017127A (es
Inventor
Gregory T Whiteker
James M Renga
Nakyen Choy
Yuanming Zhu
Original Assignee
Corteva Agriscience Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corteva Agriscience Llc filed Critical Corteva Agriscience Llc
Publication of MX2016017127A publication Critical patent/MX2016017127A/es
Publication of MX373312B publication Critical patent/MX373312B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

4,6-dibromo-3-hidroxipicolinonitrilo puede prepararse a partir de furfural en una serie de etapas químicas seleccionadas de ciano-aminación, formación de sal de amina y bromación-reordenamiento.
MX2016017127A 2014-07-08 2015-07-08 Proceso para la preparación de ácidos 4-alcoxi-3-hidroxipicolínicos. MX373312B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462021876P 2014-07-08 2014-07-08
US201462021881P 2014-07-08 2014-07-08
US201462021877P 2014-07-08 2014-07-08
PCT/US2015/039568 WO2016007637A1 (en) 2014-07-08 2015-07-08 Process for the preparation of 4-alkoxy-3-hydroxypicolinic acids

Publications (2)

Publication Number Publication Date
MX2016017127A MX2016017127A (es) 2017-05-10
MX373312B true MX373312B (es) 2020-05-20

Family

ID=55064837

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2016017106A MX369327B (es) 2014-07-08 2015-07-08 Proceso para la preparacion de acidos 4-alcoxi-3-hidroxipicolinico s.
MX2016017120A MX387774B (es) 2014-07-08 2015-07-08 Proceso para la preparacion de acidos 4-alcoxi-3-hidroxipicolinicos.
MX2016017127A MX373312B (es) 2014-07-08 2015-07-08 Proceso para la preparación de ácidos 4-alcoxi-3-hidroxipicolínicos.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2016017106A MX369327B (es) 2014-07-08 2015-07-08 Proceso para la preparacion de acidos 4-alcoxi-3-hidroxipicolinico s.
MX2016017120A MX387774B (es) 2014-07-08 2015-07-08 Proceso para la preparacion de acidos 4-alcoxi-3-hidroxipicolinicos.

Country Status (16)

Country Link
US (4) US9481651B2 (es)
EP (3) EP3166927B1 (es)
JP (4) JP6688278B2 (es)
KR (3) KR102436286B1 (es)
CN (3) CN106660957B (es)
BR (3) BR112016031007B8 (es)
CA (3) CA2954276C (es)
CO (3) CO2017000049A2 (es)
DK (3) DK3166612T3 (es)
ES (3) ES2738401T3 (es)
IL (3) IL249893B (es)
MX (3) MX369327B (es)
PL (3) PL3166612T3 (es)
TW (5) TWI684587B (es)
WO (3) WO2016007637A1 (es)
ZA (1) ZA201700254B (es)

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RU2018130270A (ru) * 2016-01-22 2020-02-25 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Способ получения 4-алкокси-3-ацетоксипиколиновых кислот
US10550083B2 (en) * 2016-01-22 2020-02-04 Dow Agrosciences Llc Processes for the preparation of 4-alkoxy-3-hydroxypicolinic acids
TW201733985A (zh) * 2016-02-29 2017-10-01 陶氏農業科學公司 用於製備4-烷氧基-3-羥基吡啶甲酸之方法
TWI733749B (zh) * 2017-01-25 2021-07-21 美商陶氏農業科學公司 用於製備4-烷氧基-3-羥基吡啶甲酸之方法
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WO2021233882A1 (en) * 2020-05-22 2021-11-25 Boehringer Ingelheim International Gmbh Process for manufacturing alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridine-carboxylate
AR123502A1 (es) 2020-09-15 2022-12-07 Pi Industries Ltd Nuevos compuestos de picolinamida para combatir hongos fitopatógenos
WO2022058877A1 (en) 2020-09-15 2022-03-24 Pi Industries Limited Novel picolinamide compounds for combating phytopathogenic fungi
UY40356A (es) 2022-07-18 2024-01-31 Pi Industries Ltd Un proceso para la síntesis de ácidos 4-alcoxi-3-hidroxipicolínicos e intermedios de los mismos.

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Also Published As

Publication number Publication date
WO2016007637A1 (en) 2016-01-14
ES2807622T3 (es) 2021-02-23
JP6688278B2 (ja) 2020-04-28
CO2017000049A2 (es) 2017-05-10
KR102441177B1 (ko) 2022-09-07
JP2020073575A (ja) 2020-05-14
CN106573005B (zh) 2020-05-29
BR112016031007B8 (pt) 2022-08-23
US20160009649A1 (en) 2016-01-14
ZA201700254B (en) 2018-12-19
CA2954284C (en) 2022-12-13
US9475771B2 (en) 2016-10-25
EP3166927A1 (en) 2017-05-17
JP2017523962A (ja) 2017-08-24
IL249893B (en) 2020-02-27
CA2954167C (en) 2023-01-03
MX369327B (es) 2019-11-05
EP3166612B1 (en) 2019-06-12
CO2017000446A2 (es) 2017-05-10
EP3166611A1 (en) 2017-05-17
IL249891B (en) 2020-07-30
IL249893A0 (en) 2017-03-30
WO2016007634A1 (en) 2016-01-14
US20160009676A1 (en) 2016-01-14
US20160009650A1 (en) 2016-01-14
EP3166611B1 (en) 2020-09-16
KR20170029501A (ko) 2017-03-15
CN106659724B (zh) 2020-04-28
IL249891A0 (en) 2017-03-30
PL3166611T3 (pl) 2021-04-06
BR112017000135B1 (pt) 2022-08-09
TW201625571A (zh) 2016-07-16
MX2016017120A (es) 2017-05-10
MX2016017127A (es) 2017-05-10
ES2738401T3 (es) 2020-01-22
KR102436286B1 (ko) 2022-08-26
BR112017000061A2 (pt) 2017-11-07
TW201625542A (zh) 2016-07-16
CA2954284A1 (en) 2016-01-14
JP2017521429A (ja) 2017-08-03
IL249911A0 (en) 2017-03-30
EP3166927A4 (en) 2017-12-20
CN106573005A (zh) 2017-04-19
WO2016007638A1 (en) 2016-01-14
TW202003481A (zh) 2020-01-16
JP6513178B2 (ja) 2019-05-15
MX387774B (es) 2025-03-18
TW201625541A (zh) 2016-07-16
CA2954276A1 (en) 2016-01-14
IL249911B (en) 2020-02-27
KR20170029506A (ko) 2017-03-15
CN106659724A (zh) 2017-05-10
TWI720647B (zh) 2021-03-01
EP3166612A4 (en) 2017-12-20
PL3166927T3 (pl) 2020-10-19
US9718783B2 (en) 2017-08-01
EP3166611A4 (en) 2018-02-21
TWI684587B (zh) 2020-02-11
BR112017000135A2 (pt) 2017-11-07
TW201943703A (zh) 2019-11-16
KR102450085B1 (ko) 2022-10-04
KR20170023942A (ko) 2017-03-06
DK3166927T3 (da) 2020-07-27
ES2836201T3 (es) 2021-06-24
US9522887B2 (en) 2016-12-20
EP3166927B1 (en) 2020-04-22
CN106660957B (zh) 2019-11-29
BR112017000061B1 (pt) 2022-10-25
TWI682923B (zh) 2020-01-21
US9481651B2 (en) 2016-11-01
BR112017000135B8 (pt) 2023-05-16
PL3166612T3 (pl) 2019-12-31
BR112017000061B8 (pt) 2023-05-16
EP3166612A1 (en) 2017-05-17
TWI689498B (zh) 2020-04-01
BR112016031007B1 (pt) 2021-04-27
MX2016017106A (es) 2017-05-10
DK3166612T3 (da) 2019-09-23
JP6625115B2 (ja) 2019-12-25
DK3166611T3 (da) 2020-12-07
US20170044105A1 (en) 2017-02-16
CN106660957A (zh) 2017-05-10
CA2954167A1 (en) 2016-01-14
CO2017000430A2 (es) 2017-04-28
CA2954276C (en) 2022-12-13
JP2017523960A (ja) 2017-08-24

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