DK3166927T3 - Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxy-picolinsyre - Google Patents
Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxy-picolinsyre Download PDFInfo
- Publication number
- DK3166927T3 DK3166927T3 DK15818435.8T DK15818435T DK3166927T3 DK 3166927 T3 DK3166927 T3 DK 3166927T3 DK 15818435 T DK15818435 T DK 15818435T DK 3166927 T3 DK3166927 T3 DK 3166927T3
- Authority
- DK
- Denmark
- Prior art keywords
- alcohy
- hydroxy
- preparing
- picolic acid
- picolic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/803—Processes of preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462021881P | 2014-07-08 | 2014-07-08 | |
US201462021876P | 2014-07-08 | 2014-07-08 | |
US201462021877P | 2014-07-08 | 2014-07-08 | |
PCT/US2015/039569 WO2016007638A1 (en) | 2014-07-08 | 2015-07-08 | Process for the preparation of 4-alkoxy-3-hydroxypicolinic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3166927T3 true DK3166927T3 (da) | 2020-07-27 |
Family
ID=55064837
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK15818435.8T DK3166927T3 (da) | 2014-07-08 | 2015-07-08 | Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxy-picolinsyre |
DK15818752.6T DK3166611T3 (da) | 2014-07-08 | 2015-07-08 | Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxypicolinsyrer |
DK15819075.1T DK3166612T3 (da) | 2014-07-08 | 2015-07-08 | Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxy-picolinsyre |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK15818752.6T DK3166611T3 (da) | 2014-07-08 | 2015-07-08 | Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxypicolinsyrer |
DK15819075.1T DK3166612T3 (da) | 2014-07-08 | 2015-07-08 | Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxy-picolinsyre |
Country Status (16)
Country | Link |
---|---|
US (4) | US9522887B2 (da) |
EP (3) | EP3166927B1 (da) |
JP (4) | JP6513178B2 (da) |
KR (3) | KR102436286B1 (da) |
CN (3) | CN106660957B (da) |
BR (3) | BR112016031007B8 (da) |
CA (3) | CA2954284C (da) |
CO (3) | CO2017000049A2 (da) |
DK (3) | DK3166927T3 (da) |
ES (3) | ES2836201T3 (da) |
IL (3) | IL249893B (da) |
MX (3) | MX369327B (da) |
PL (3) | PL3166611T3 (da) |
TW (5) | TWI682923B (da) |
WO (3) | WO2016007634A1 (da) |
ZA (1) | ZA201700254B (da) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10476159B2 (en) * | 2015-11-30 | 2019-11-12 | Electronics And Telecommunications Research Institute | Coaxial resonance coil having toroidal shape for wireless power transmission |
ES2883118T3 (es) * | 2016-01-22 | 2021-12-07 | Corteva Agriscience Llc | Procedimiento para la preparación de ácidos 4-alcoxi-3-hidroxipicolínicos |
CN108495845A (zh) * | 2016-01-22 | 2018-09-04 | 美国陶氏益农公司 | 制备4-烷氧基-3-乙酰氧基吡啶甲酸的方法 |
TW201733985A (zh) * | 2016-02-29 | 2017-10-01 | 陶氏農業科學公司 | 用於製備4-烷氧基-3-羥基吡啶甲酸之方法 |
TWI733749B (zh) * | 2017-01-25 | 2021-07-21 | 美商陶氏農業科學公司 | 用於製備4-烷氧基-3-羥基吡啶甲酸之方法 |
US10382579B2 (en) * | 2017-02-28 | 2019-08-13 | International Business Machines Corporation | Personalized location-based services for users |
EP4214203A1 (en) | 2020-09-15 | 2023-07-26 | PI Industries Ltd. | Novel picolinamide compounds for combating phytopathogenic fungi |
WO2022058877A1 (en) | 2020-09-15 | 2022-03-24 | Pi Industries Limited | Novel picolinamide compounds for combating phytopathogenic fungi |
WO2024018354A1 (en) | 2022-07-18 | 2024-01-25 | Pi Industries Ltd. | A process for the synthesis of 4-alkoxy-3-hydroxypicolinic acids and intermediates thereof |
Family Cites Families (34)
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CH617452A5 (da) * | 1974-10-25 | 1980-05-30 | Hoffmann La Roche | |
ZA815129B (en) * | 1980-07-28 | 1982-07-28 | Ciba Geigy Ag | Thiazoline derivatives and processes for their manufacture |
DE3170401D1 (en) * | 1980-07-28 | 1985-06-13 | Ciba Geigy Ag | Triazoline derivatives and processes for their preparation |
GB2095237B (en) | 1981-03-19 | 1985-04-03 | Ici Plc | Herbicidal and fungicidal substituted n-furyl or thienyl-methyl amides |
JP4463420B2 (ja) | 1998-02-06 | 2010-05-19 | 明治製菓株式会社 | 新規抗真菌化合物とその製法 |
WO2000026191A1 (fr) * | 1998-11-04 | 2000-05-11 | Meiji Seika Kaisha, Ltd. | Derives de picolinamide et pesticides contenant ces derives comme ingredient actif |
AU2560000A (en) * | 1999-02-20 | 2000-09-04 | Astrazeneca Ab | Di- and tripeptide nitrile derivatives as inhibitors of cathepsin l and cathepsin |
ES2546386T3 (es) * | 1999-07-20 | 2015-09-23 | Dow Agrosciences, Llc | Amidas aromáticas heterocíclicas fungicidas y sus composiciones, métodos de uso y preparación |
US20020177578A1 (en) | 1999-07-20 | 2002-11-28 | Ricks Michael J. | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation |
EP1516874B1 (en) | 1999-07-20 | 2015-08-19 | Dow AgroSciences LLC | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation |
US6355660B1 (en) | 1999-07-20 | 2002-03-12 | Dow Agrosciences Llc | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation |
US20050239873A1 (en) | 1999-08-20 | 2005-10-27 | Fred Hutchinson Cancer Research Center | 2 Methoxy antimycin a derivatives and methods of use |
CZ2002487A3 (cs) * | 1999-08-20 | 2002-06-12 | Dow Agrosciences Llc | Fungicidní heterocyklické aromatické amidy, prostředky na jejich bázi, způsoby jejich pouľití a přípravy |
EP1412351A4 (en) | 2001-07-31 | 2005-04-06 | Dow Agrosciences Llc | REDUCTIVE CLEAVAGE OF THE EXOCYCLIC ESTERS OF UK 2A OR BZW. DERIVATIVES AND PRODUCTS MADE THEREFROM |
US6903219B2 (en) | 2001-10-05 | 2005-06-07 | Dow Agrosciences Llc | Process to produce derivatives from UK-2A derivatives |
AR037328A1 (es) | 2001-10-23 | 2004-11-03 | Dow Agrosciences Llc | Compuesto de [7-bencil-2,6-dioxo-1,5-dioxonan-3-il]-4-metoxipiridin-2-carboxamida, composicion que lo comprende y metodo que lo utiliza |
WO2004056774A2 (en) * | 2002-12-19 | 2004-07-08 | Neurogen Corporation | Substituted biphenyl-4-carboxylic acid arylamide analogues as capsaicin receptor modulators |
EA008225B1 (ru) | 2003-05-28 | 2007-04-27 | Басф Акциенгезельшафт | Фунгицидные смеси, содержащие их фунгицидное средство и посевной материал, и способ применения фунгицидных смесей |
DE10347090A1 (de) | 2003-10-10 | 2005-05-04 | Bayer Cropscience Ag | Synergistische fungizide Wirkstoffkombinationen |
US20050176767A1 (en) * | 2003-10-30 | 2005-08-11 | Laval Chan Chun Kong | Pyridine carboxamide and methods for inhibiting HIV integrase |
WO2008051533A2 (en) * | 2006-10-25 | 2008-05-02 | Takeda Pharmaceutical Company Limited | Benzimidazole compounds |
EA201000429A1 (ru) | 2007-09-26 | 2010-10-29 | Басф Се | Трехкомпонентные фунгицидные композиции, включающие боскалид и хлороталонил |
PL2296467T3 (pl) | 2008-05-30 | 2016-04-29 | Dow Agrosciences Llc | Sposoby zwalczania patogenów grzybiczych odpornych na qoi |
EP2473483A4 (en) | 2009-09-01 | 2013-10-16 | Dow Agrosciences Llc | SYNERGISTIC FUNGICIDE COMPOSITIONS CONTAINING A 5-FLUOROPYRIMIDINE DERIVATIVE FOR FUNGUS CONTROL IN CEREALS |
JP5655080B2 (ja) | 2009-10-07 | 2015-01-14 | ダウ アグロサイエンシィズ エルエルシー | 穀類において真菌を制御するための5−フルオロシトシンを含有する相乗的殺真菌組成物 |
PT3153020T (pt) | 2009-10-07 | 2019-02-26 | Dow Agrosciences Llc | Misturas fungicidas sinérgicas para o controlo de fungos em cereais |
EA022245B1 (ru) | 2009-12-08 | 2015-11-30 | Басф Се | Пестицидные смеси |
WO2012070015A1 (en) | 2010-11-24 | 2012-05-31 | Stemergie Biotechnology Sa | Inhibitors of the activity of complex iii of the mitochondrial electron transport chain and use thereof for treating diseases |
JP6013032B2 (ja) | 2011-07-08 | 2016-10-25 | 石原産業株式会社 | 殺菌剤組成物及び植物病害の防除方法 |
RU2014149186A (ru) | 2012-05-07 | 2016-06-27 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Макроциклические пиколинамиды в качестве фунгицидов |
WO2013169664A2 (en) | 2012-05-07 | 2013-11-14 | Dow Agrosciences Llc | Macrocycle picolinamides as fungicides |
DK2847188T3 (da) | 2012-05-07 | 2017-04-03 | Dow Agrosciences Llc | Makrocykliske picolinamides som fungicider |
AU2013370491B2 (en) | 2012-12-28 | 2016-10-06 | Corteva Agriscience Llc | Synergistic fungicidal mixtures for fungal control in cereals |
JP2016507511A (ja) | 2012-12-31 | 2016-03-10 | ダウ アグロサイエンシィズ エルエルシー | 殺真菌剤としての大環状ピコリンアミド |
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2015
- 2015-07-08 ES ES15818752T patent/ES2836201T3/es active Active
- 2015-07-08 CA CA2954284A patent/CA2954284C/en active Active
- 2015-07-08 CN CN201580036749.4A patent/CN106660957B/zh active Active
- 2015-07-08 BR BR112016031007A patent/BR112016031007B8/pt active IP Right Grant
- 2015-07-08 WO PCT/US2015/039565 patent/WO2016007634A1/en active Application Filing
- 2015-07-08 WO PCT/US2015/039568 patent/WO2016007637A1/en active Application Filing
- 2015-07-08 MX MX2016017106A patent/MX369327B/es active IP Right Grant
- 2015-07-08 KR KR1020177000726A patent/KR102436286B1/ko active IP Right Grant
- 2015-07-08 CN CN201580036750.7A patent/CN106573005B/zh active Active
- 2015-07-08 DK DK15818435.8T patent/DK3166927T3/da active
- 2015-07-08 DK DK15818752.6T patent/DK3166611T3/da active
- 2015-07-08 ES ES15819075T patent/ES2738401T3/es active Active
- 2015-07-08 ES ES15818435T patent/ES2807622T3/es active Active
- 2015-07-08 DK DK15819075.1T patent/DK3166612T3/da active
- 2015-07-08 CN CN201580036748.XA patent/CN106659724B/zh active Active
- 2015-07-08 TW TW104122162A patent/TWI682923B/zh active
- 2015-07-08 PL PL15818752T patent/PL3166611T3/pl unknown
- 2015-07-08 US US14/794,430 patent/US9522887B2/en active Active
- 2015-07-08 WO PCT/US2015/039569 patent/WO2016007638A1/en active Application Filing
- 2015-07-08 TW TW104122166A patent/TWI684587B/zh active
- 2015-07-08 JP JP2017500360A patent/JP6513178B2/ja active Active
- 2015-07-08 CA CA2954276A patent/CA2954276C/en active Active
- 2015-07-08 BR BR112017000061A patent/BR112017000061B8/pt active IP Right Grant
- 2015-07-08 EP EP15818435.8A patent/EP3166927B1/en active Active
- 2015-07-08 TW TW108136698A patent/TWI720647B/zh active
- 2015-07-08 KR KR1020177000805A patent/KR102450085B1/ko active IP Right Grant
- 2015-07-08 JP JP2017500029A patent/JP6688278B2/ja active Active
- 2015-07-08 EP EP15819075.1A patent/EP3166612B1/en active Active
- 2015-07-08 TW TW108129670A patent/TW201943703A/zh unknown
- 2015-07-08 US US14/794,471 patent/US9475771B2/en active Active
- 2015-07-08 EP EP15818752.6A patent/EP3166611B1/en active Active
- 2015-07-08 MX MX2016017127A patent/MX2016017127A/es active IP Right Grant
- 2015-07-08 BR BR112017000135A patent/BR112017000135B8/pt active IP Right Grant
- 2015-07-08 TW TW104122167A patent/TWI689498B/zh active
- 2015-07-08 KR KR1020177000806A patent/KR102441177B1/ko active IP Right Grant
- 2015-07-08 US US14/794,450 patent/US9481651B2/en active Active
- 2015-07-08 PL PL15818435T patent/PL3166927T3/pl unknown
- 2015-07-08 CA CA2954167A patent/CA2954167C/en active Active
- 2015-07-08 MX MX2016017120A patent/MX2016017120A/es unknown
- 2015-07-08 PL PL15819075T patent/PL3166612T3/pl unknown
- 2015-07-08 JP JP2017500905A patent/JP6625115B2/ja active Active
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2016
- 2016-10-31 US US15/339,190 patent/US9718783B2/en active Active
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2017
- 2017-01-02 IL IL249893A patent/IL249893B/en active IP Right Grant
- 2017-01-02 IL IL249891A patent/IL249891B/en active IP Right Grant
- 2017-01-03 IL IL249911A patent/IL249911B/en active IP Right Grant
- 2017-01-04 CO CONC2017/0000049A patent/CO2017000049A2/es unknown
- 2017-01-11 ZA ZA2017/00254A patent/ZA201700254B/en unknown
- 2017-01-19 CO CONC2017/0000430A patent/CO2017000430A2/es unknown
- 2017-01-19 CO CONC2017/0000446A patent/CO2017000446A2/es unknown
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2020
- 2020-01-20 JP JP2020006857A patent/JP2020073575A/ja not_active Withdrawn
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