MX369477B - Formulaciones farmacéuticas de estatinas y ácidos grasos omega-3 para encapsulación. - Google Patents
Formulaciones farmacéuticas de estatinas y ácidos grasos omega-3 para encapsulación.Info
- Publication number
- MX369477B MX369477B MX2012013933A MX2012013933A MX369477B MX 369477 B MX369477 B MX 369477B MX 2012013933 A MX2012013933 A MX 2012013933A MX 2012013933 A MX2012013933 A MX 2012013933A MX 369477 B MX369477 B MX 369477B
- Authority
- MX
- Mexico
- Prior art keywords
- phase
- omega
- fatty acids
- dosage form
- statins
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- General Preparation And Processing Of Foods (AREA)
- Jellies, Jams, And Syrups (AREA)
Abstract
Una forma de dosificación de gelatina blanda de múltiples fases que comprende por lo menos una forma de dosificación sólida preformada que comprende un compuesto de estatina y por lo menos una fase de relleno líquida que comprende ácidos grasos Omega-3. Las formas de dosificación de gelatina blanda de múltiples fases de la presente invención son especialmente útiles para combinar por lo menos una forma de dosificación sólida y por lo menos una fase líquida para una sola ingestión. La fase sólida, la fase líquida o los recubrimientos además pueden comprender ingredientes farmacéuticos activos, nutracéuticos, suplementos nutricionales, o sustancias terapéuticas, excipientes convencionales o combinaciones de los mismos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2706270A CA2706270C (en) | 2010-06-03 | 2010-06-03 | Pharmaceutical formulations of statins and omega-3 fatty acids for encapsulation |
PCT/CA2011/000650 WO2011150505A1 (en) | 2010-06-03 | 2011-06-03 | Pharmaceutical formulations of statins and omega-3 fatty acids for encapsulation |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2012013933A MX2012013933A (es) | 2013-02-11 |
MX369477B true MX369477B (es) | 2019-11-08 |
Family
ID=45066009
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012013933A MX369477B (es) | 2010-06-03 | 2011-06-03 | Formulaciones farmacéuticas de estatinas y ácidos grasos omega-3 para encapsulación. |
MX2019013095A MX2019013095A (es) | 2010-06-03 | 2012-11-29 | Formulaciones farmaceuticas de estatinas y acidos grasos omega-3 para encapsulacion. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019013095A MX2019013095A (es) | 2010-06-03 | 2012-11-29 | Formulaciones farmaceuticas de estatinas y acidos grasos omega-3 para encapsulacion. |
Country Status (12)
Country | Link |
---|---|
US (2) | US11975108B2 (es) |
EP (2) | EP2575787B1 (es) |
JP (2) | JP5972261B2 (es) |
AU (1) | AU2011261117B2 (es) |
CA (1) | CA2706270C (es) |
DK (1) | DK2575787T3 (es) |
ES (1) | ES2807498T3 (es) |
HU (1) | HUE050830T2 (es) |
MX (2) | MX369477B (es) |
PL (1) | PL2575787T3 (es) |
PT (1) | PT2575787T (es) |
WO (1) | WO2011150505A1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014095628A1 (en) * | 2012-12-17 | 2014-06-26 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Oral formulation containing a statin in omega-3 polyunsaturated fatty acids (n-3 pufa) |
CA2926335C (en) | 2013-10-30 | 2021-11-23 | Banner Life Sciences Llc | Enteric soft capsules comprising polyunsaturated fatty acids |
US9636318B2 (en) | 2015-08-31 | 2017-05-02 | Banner Life Sciences Llc | Fumarate ester dosage forms |
US9326965B2 (en) | 2014-02-28 | 2016-05-03 | Banner Life Sciences Llc | Controlled release fumarate esters |
US9326947B1 (en) | 2014-02-28 | 2016-05-03 | Banner Life Sciences Llc | Controlled release fumarate esters |
US10098863B2 (en) | 2014-02-28 | 2018-10-16 | Banner Life Sciences Llc | Fumarate esters |
WO2015185240A1 (en) | 2014-06-04 | 2015-12-10 | Sigma-Tau Industrire Farmaceutiche Riunite S.P.A. | Compositions containing simvastatin in omega-3 polyunsaturated fatty acids |
US9895333B2 (en) | 2014-06-26 | 2018-02-20 | Patheon Softgels Inc. | Enhanced bioavailability of polyunsaturated fatty acids |
CA2950444C (en) * | 2014-06-26 | 2021-01-12 | Banner Life Sciences Llc | Enhanced bioavailability of polyunsaturated fatty acids |
CN106794149A (zh) * | 2014-08-13 | 2017-05-31 | 韩国联合制药株式会社 | 含ω‑3脂肪酸酯和他汀类的口服给药复合制剂 |
KR101950907B1 (ko) * | 2016-02-05 | 2019-02-21 | 한국유나이티드제약 주식회사 | 지용성 약물 및 방유성 기제가 코팅된 고형제제를 포함하는 경구용 복합제제 |
WO2017171484A1 (ko) * | 2016-03-31 | 2017-10-05 | 한미약품 주식회사 | 오메가-3 지방산 또는 이의 에스테르, 및 하이드록시메틸글루타릴 코엔자임에이 환원효소 억제제를 포함하는 경구용 복합 제제 |
US11547693B2 (en) | 2019-07-29 | 2023-01-10 | Matthias Rath | Ascorbate in the prevention of statin induced vascular calcification |
US10736872B1 (en) * | 2019-09-05 | 2020-08-11 | Matthias W. Rath | Pharmaceutical mixture to treat statin induced vascular calcification |
WO2021142062A1 (en) | 2020-01-10 | 2021-07-15 | Banner Life Sciences Llc | Fumarate ester dosage forms with enhanced gastrointestinal tolerability |
EP4185277A4 (en) * | 2020-07-23 | 2024-08-07 | Procaps Sa | SOFT-SHELL GELATIN CAPSULES |
BR102021011153B1 (pt) | 2021-06-09 | 2022-12-27 | Fernando Campos Barbosa | Composição fitoterápica associada a suplementos polivitamínicos e minerais |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1803440A (en) * | 1929-07-25 | 1931-05-05 | Newspaper Mechanical Sales Com | Coin control for vending machines |
US2775080A (en) | 1950-05-26 | 1956-12-25 | American Cyanamid Co | Method of forming powder-and-liquid filled capsules |
US2711814A (en) * | 1953-08-14 | 1955-06-28 | Bartlett And Company Grain | Apparatus for cleaning flat bottom grain tanks |
US3536074A (en) | 1968-03-29 | 1970-10-27 | Alfred Aufhauser | Oral administration of a pill,tablet or capsule |
US4655027A (en) | 1980-11-24 | 1987-04-07 | Chasman Sydney A | Method and apparatus for forming capsules |
JPH08511559A (ja) * | 1993-06-18 | 1996-12-03 | スミスクライン・ビーチャム・コーポレイション | 軟外皮ゼラチンに封入された粒子 |
EP1792616B1 (en) * | 1997-07-31 | 2009-12-16 | Abbott Respiratory LLC | Composition comprising an HMG-CoA inhibitor and a nicotinic acid compound for treating hyperlipidemia |
US6238616B1 (en) | 1998-12-14 | 2001-05-29 | Timecaps Inc. | Method of manufacturing gelatin capsule containing powder or time release pellets |
US6574945B2 (en) | 2001-03-21 | 2003-06-10 | Lumitek Llc | Method for manufacturing a projectile containing chemiluminescent compounds |
ATE358477T1 (de) * | 2001-06-12 | 2007-04-15 | Galephar M F | Oral anzuwendende arzneizusammensetzung enthaltend ein statinderivat |
WO2004000731A2 (en) | 2002-06-25 | 2003-12-31 | Akzo Nobel N.V. | Use of cationic layered materials, compositions comprising these materials, and the preparation of cationic layered materials |
FR2850275B1 (fr) * | 2003-01-24 | 2005-04-08 | Scherer Technologies Inc R P | Capsules molles a macher contenant une substance active a gout masque |
US20040146537A1 (en) * | 2003-01-28 | 2004-07-29 | Ramachandran Radhakrishnan | Oily wax matrix suspension formulation comprising pharmacologically active agents |
CA2475765A1 (en) | 2003-07-29 | 2005-01-29 | L. Perrigo Company | Tablet encapsulating machine |
CN101318923A (zh) * | 2003-09-17 | 2008-12-10 | 沃尼尔·朗伯有限责任公司 | [R-(R*,R*)]-2-(4-氟苯基)-β,δ-二羟基-5-(1-甲基乙基)-3-苯基-4-[(苯基氨基)羰基]-1H-吡咯-1-庚酸的结晶形式 |
ES2255426B1 (es) * | 2004-10-19 | 2007-08-16 | Gp Pharm, S.A. | Formulacion farmaceutica que comprende microcapsulas de estatinas suspendidas en ester alquilicos de acidos grasos poliinsaturados (pufa). |
US20070191467A1 (en) * | 2004-12-06 | 2007-08-16 | Reliant Pharmaceutical, Inc. | Statin and omega-3 fatty acids for lipid therapy |
EA200701913A1 (ru) * | 2005-03-08 | 2008-08-29 | Релайэнт Фармасьютикалз, Инк. | Лечение статином, омега-3 жирными кислотами и их комбинированным продуктом |
US7887852B2 (en) * | 2005-06-03 | 2011-02-15 | Soft Gel Technologies, Inc. | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols |
WO2006136196A1 (en) * | 2005-06-21 | 2006-12-28 | V. Mane Fils | Gellan seamless breakable capsule and process for manufacturing thereof |
ES2511772T3 (es) * | 2005-12-20 | 2014-10-23 | Cenestra, Llc | Formulaciones de ácidos grasos omega-3 |
US8784886B2 (en) | 2006-03-09 | 2014-07-22 | GlaxoSmithKline, LLC | Coating capsules with active pharmaceutical ingredients |
WO2007103557A2 (en) * | 2006-03-09 | 2007-09-13 | Reliant Pharmaceuticals, Inc. | Coating capsules with active pharmaceutical ingredients |
US20070218141A1 (en) * | 2006-03-15 | 2007-09-20 | Ashis Kumar Mehta | Simvastatin compositions |
US20100310650A1 (en) * | 2006-06-26 | 2010-12-09 | Roberto Valducci | Pharmaceutical composition for the oral administration of omega polyenoic fatty acids and one or more active principles incompatible therewith, and a process for its preparation |
EP2431043A1 (en) * | 2007-05-23 | 2012-03-21 | Amcol International Corporation | Cholesterol-interacting layered phyllosilicates for suppressing gastrointestinal cholesterol absorption |
ITMI20072142A1 (it) * | 2007-11-08 | 2009-05-09 | Yervant Zarmanian | Composizioni farmaceutiche contenenti statine e derivati di acidi grassi omega-3 |
EP2455070A1 (en) * | 2008-01-10 | 2012-05-23 | Takeda Pharmaceutical Company Limited | Capsule Formulation |
WO2009151116A1 (ja) * | 2008-06-13 | 2009-12-17 | 持田製薬株式会社 | 非アルコール性脂肪肝炎の予防/改善・治療薬 |
US20100062057A1 (en) * | 2008-09-10 | 2010-03-11 | Pronova BioPharma Norge AS. | Formulation |
GB0818472D0 (en) * | 2008-10-08 | 2008-11-12 | Probio Nutraceuticals As | Composition |
CA3065589C (en) * | 2010-06-03 | 2022-04-26 | Catalent Ontario Limited | Multi phase soft gel capsules, apparatus and method thereof |
-
2010
- 2010-06-03 CA CA2706270A patent/CA2706270C/en active Active
-
2011
- 2011-06-03 MX MX2012013933A patent/MX369477B/es active IP Right Grant
- 2011-06-03 JP JP2013512707A patent/JP5972261B2/ja active Active
- 2011-06-03 AU AU2011261117A patent/AU2011261117B2/en active Active
- 2011-06-03 EP EP11789014.5A patent/EP2575787B1/en active Active
- 2011-06-03 PT PT117890145T patent/PT2575787T/pt unknown
- 2011-06-03 DK DK11789014.5T patent/DK2575787T3/da active
- 2011-06-03 ES ES11789014T patent/ES2807498T3/es active Active
- 2011-06-03 US US13/701,463 patent/US11975108B2/en active Active
- 2011-06-03 HU HUE11789014A patent/HUE050830T2/hu unknown
- 2011-06-03 EP EP19189074.8A patent/EP3581173B1/en active Active
- 2011-06-03 WO PCT/CA2011/000650 patent/WO2011150505A1/en active Application Filing
- 2011-06-03 PL PL11789014T patent/PL2575787T3/pl unknown
-
2012
- 2012-11-29 MX MX2019013095A patent/MX2019013095A/es unknown
-
2016
- 2016-05-06 JP JP2016093142A patent/JP2016138143A/ja active Pending
-
2023
- 2023-04-03 US US18/130,142 patent/US20230233472A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP2575787B1 (en) | 2020-05-27 |
HUE050830T2 (hu) | 2021-01-28 |
EP2575787A4 (en) | 2013-11-27 |
JP2016138143A (ja) | 2016-08-04 |
US20230233472A1 (en) | 2023-07-27 |
MX2019013095A (es) | 2020-01-30 |
AU2011261117A1 (en) | 2012-12-13 |
JP5972261B2 (ja) | 2016-08-17 |
AU2011261117B2 (en) | 2015-08-13 |
CA2706270A1 (en) | 2011-12-03 |
EP3581173A1 (en) | 2019-12-18 |
DK2575787T3 (da) | 2020-08-03 |
CA2706270C (en) | 2020-01-07 |
WO2011150505A1 (en) | 2011-12-08 |
PT2575787T (pt) | 2020-07-28 |
US11975108B2 (en) | 2024-05-07 |
MX2012013933A (es) | 2013-02-11 |
PL2575787T3 (pl) | 2020-11-02 |
EP2575787A1 (en) | 2013-04-10 |
US20130115281A1 (en) | 2013-05-09 |
JP2013527205A (ja) | 2013-06-27 |
EP3581173B1 (en) | 2024-08-28 |
ES2807498T3 (es) | 2021-02-23 |
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Legal Events
Date | Code | Title | Description |
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FG | Grant or registration |