DK2575787T3 - Farmaceutiske formuleringer af statiner og omega-3-fedtsyrer til indkapsling - Google Patents

Farmaceutiske formuleringer af statiner og omega-3-fedtsyrer til indkapsling Download PDF

Info

Publication number
DK2575787T3
DK2575787T3 DK11789014.5T DK11789014T DK2575787T3 DK 2575787 T3 DK2575787 T3 DK 2575787T3 DK 11789014 T DK11789014 T DK 11789014T DK 2575787 T3 DK2575787 T3 DK 2575787T3
Authority
DK
Denmark
Prior art keywords
statins
omega
encapsulation
fatty acids
pharmaceutical formulations
Prior art date
Application number
DK11789014.5T
Other languages
English (en)
Inventor
Peter Draper
James Draper
Beth Okutan
Original Assignee
Catalent Ontario Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Catalent Ontario Ltd filed Critical Catalent Ontario Ltd
Application granted granted Critical
Publication of DK2575787T3 publication Critical patent/DK2575787T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • General Preparation And Processing Of Foods (AREA)
DK11789014.5T 2010-06-03 2011-06-03 Farmaceutiske formuleringer af statiner og omega-3-fedtsyrer til indkapsling DK2575787T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA2706270A CA2706270C (en) 2010-06-03 2010-06-03 Pharmaceutical formulations of statins and omega-3 fatty acids for encapsulation
PCT/CA2011/000650 WO2011150505A1 (en) 2010-06-03 2011-06-03 Pharmaceutical formulations of statins and omega-3 fatty acids for encapsulation

Publications (1)

Publication Number Publication Date
DK2575787T3 true DK2575787T3 (da) 2020-08-03

Family

ID=45066009

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11789014.5T DK2575787T3 (da) 2010-06-03 2011-06-03 Farmaceutiske formuleringer af statiner og omega-3-fedtsyrer til indkapsling

Country Status (12)

Country Link
US (2) US11975108B2 (da)
EP (3) EP3581173B1 (da)
JP (2) JP5972261B2 (da)
AU (1) AU2011261117B2 (da)
CA (1) CA2706270C (da)
DK (1) DK2575787T3 (da)
ES (1) ES2807498T3 (da)
HU (1) HUE050830T2 (da)
MX (2) MX369477B (da)
PL (1) PL2575787T3 (da)
PT (1) PT2575787T (da)
WO (1) WO2011150505A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014095628A1 (en) * 2012-12-17 2014-06-26 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Oral formulation containing a statin in omega-3 polyunsaturated fatty acids (n-3 pufa)
US9895332B2 (en) 2013-10-30 2018-02-20 Patheon Softgels, Inc. Enteric soft capsules comprising polyunsaturated fatty acids
AU2015222880B2 (en) 2014-02-28 2016-11-24 Banner Life Sciences Llc Controlled release enteric soft capsules of fumarate esters
US10098863B2 (en) 2014-02-28 2018-10-16 Banner Life Sciences Llc Fumarate esters
US9636318B2 (en) 2015-08-31 2017-05-02 Banner Life Sciences Llc Fumarate ester dosage forms
US9326947B1 (en) 2014-02-28 2016-05-03 Banner Life Sciences Llc Controlled release fumarate esters
WO2015185240A1 (en) 2014-06-04 2015-12-10 Sigma-Tau Industrire Farmaceutiche Riunite S.P.A. Compositions containing simvastatin in omega-3 polyunsaturated fatty acids
CA2950444C (en) * 2014-06-26 2021-01-12 Banner Life Sciences Llc Enhanced bioavailability of polyunsaturated fatty acids
US9895333B2 (en) 2014-06-26 2018-02-20 Patheon Softgels Inc. Enhanced bioavailability of polyunsaturated fatty acids
KR101752700B1 (ko) * 2014-08-13 2017-07-03 한국유나이티드제약 주식회사 오메가-3 지방산 에스테르 및 스타틴계 약물을 포함하는 경구용 복합제제
KR101950907B1 (ko) * 2016-02-05 2019-02-21 한국유나이티드제약 주식회사 지용성 약물 및 방유성 기제가 코팅된 고형제제를 포함하는 경구용 복합제제
WO2017171484A1 (ko) * 2016-03-31 2017-10-05 한미약품 주식회사 오메가-3 지방산 또는 이의 에스테르, 및 하이드록시메틸글루타릴 코엔자임에이 환원효소 억제제를 포함하는 경구용 복합 제제
US11547693B2 (en) 2019-07-29 2023-01-10 Matthias Rath Ascorbate in the prevention of statin induced vascular calcification
US10736872B1 (en) * 2019-09-05 2020-08-11 Matthias W. Rath Pharmaceutical mixture to treat statin induced vascular calcification
US11903918B2 (en) 2020-01-10 2024-02-20 Banner Life Sciences Llc Fumarate ester dosage forms with enhanced gastrointestinal tolerability
EP4185277A4 (en) * 2020-07-23 2024-08-07 Procaps SA Soft shell gelatin capsules
BR102021011153B1 (pt) 2021-06-09 2022-12-27 Fernando Campos Barbosa Composição fitoterápica associada a suplementos polivitamínicos e minerais
KR20240029726A (ko) * 2021-07-23 2024-03-06 프로캡스 에스에이 연질 쉘 젤라틴 캡슐

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1803440A (en) * 1929-07-25 1931-05-05 Newspaper Mechanical Sales Com Coin control for vending machines
US2775080A (en) 1950-05-26 1956-12-25 American Cyanamid Co Method of forming powder-and-liquid filled capsules
US2711814A (en) * 1953-08-14 1955-06-28 Bartlett And Company Grain Apparatus for cleaning flat bottom grain tanks
US3536074A (en) 1968-03-29 1970-10-27 Alfred Aufhauser Oral administration of a pill,tablet or capsule
US4655027A (en) 1980-11-24 1987-04-07 Chasman Sydney A Method and apparatus for forming capsules
HUT75670A (en) * 1993-06-18 1997-05-28 Smithkline Beecham Corp Soft-shelled gelatin encapsulated particles and process for its production
IL134271A0 (en) * 1997-07-31 2001-04-30 Kos Pharma Inc Combinations of hmg-coa reductase inhibitors and nicotinic acid compounds and methods for treating hyperlipidemia once a day at night
US6238616B1 (en) 1998-12-14 2001-05-29 Timecaps Inc. Method of manufacturing gelatin capsule containing powder or time release pellets
US6574945B2 (en) 2001-03-21 2003-06-10 Lumitek Llc Method for manufacturing a projectile containing chemiluminescent compounds
DE60219307T2 (de) * 2001-06-12 2008-01-10 Galephar M/F Oral anzuwendende arzneizusammensetzung enthaltend ein statinderivat
JP4276622B2 (ja) 2002-06-25 2009-06-10 アルベマーレ ネザーランズ ビー．ブイ． カチオン性層状物質の使用法、これらの物質を含む組成物、及びカチオン性層状物質の製造法
FR2850275B1 (fr) * 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
US20040146537A1 (en) * 2003-01-28 2004-07-29 Ramachandran Radhakrishnan Oily wax matrix suspension formulation comprising pharmacologically active agents
CA2475765A1 (en) 2003-07-29 2005-01-29 L. Perrigo Company Tablet encapsulating machine
US20070276027A1 (en) * 2003-09-17 2007-11-29 Warner-Lambert Company Llc Crystalline Forms of [R-(R* ,R*)]-2-(4-Fluorophenyl)-Beta, -Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-[(Phenylamino)Carbonyl]-1H-Pyrrole-1-Heptanoic Acid
CN1993121A (zh) * 2004-08-06 2007-07-04 变换药品公司 新的他汀药物组合物及相关治疗方法
ES2255426B1 (es) * 2004-10-19 2007-08-16 Gp Pharm, S.A. Formulacion farmaceutica que comprende microcapsulas de estatinas suspendidas en ester alquilicos de acidos grasos poliinsaturados (pufa).
US20070191467A1 (en) * 2004-12-06 2007-08-16 Reliant Pharmaceutical, Inc. Statin and omega-3 fatty acids for lipid therapy
EA200701913A1 (ru) * 2005-03-08 2008-08-29 Релайэнт Фармасьютикалз, Инк. Лечение статином, омега-3 жирными кислотами и их комбинированным продуктом
US7887852B2 (en) * 2005-06-03 2011-02-15 Soft Gel Technologies, Inc. Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols
WO2006136196A1 (en) * 2005-06-21 2006-12-28 V. Mane Fils Gellan seamless breakable capsule and process for manufacturing thereof
EP2364701A1 (en) * 2005-12-20 2011-09-14 Cenestra, Llc Omega-3 fatty acid formulations
WO2007103557A2 (en) * 2006-03-09 2007-09-13 Reliant Pharmaceuticals, Inc. Coating capsules with active pharmaceutical ingredients
US8784886B2 (en) 2006-03-09 2014-07-22 GlaxoSmithKline, LLC Coating capsules with active pharmaceutical ingredients
US20070218141A1 (en) * 2006-03-15 2007-09-20 Ashis Kumar Mehta Simvastatin compositions
EP2046305A2 (en) * 2006-06-26 2009-04-15 Valpharma S.A. Pharmaceutical composition for the oral administration of omega polyenoic fatty acids
EP2167069B1 (en) * 2007-05-23 2011-10-26 Amcol International Corporation Cholesterol-interacting layered phyllosilicates and methods of reducing hypercholesteremia in a mammal
ITMI20072142A1 (it) * 2007-11-08 2009-05-09 Yervant Zarmanian Composizioni farmaceutiche contenenti statine e derivati di acidi grassi omega-3
UA100403C2 (en) * 2008-01-10 2012-12-25 Такеда Фармасьютикал Компани Лимитед Capsule formulation
US20110082119A1 (en) * 2008-06-13 2011-04-07 Takashi Yano Prophylactic/ameliorating or therapeutic agent for non-alcoholic steatohepatitis
US20100062057A1 (en) * 2008-09-10 2010-03-11 Pronova BioPharma Norge AS. Formulation
GB0818472D0 (en) * 2008-10-08 2008-11-12 Probio Nutraceuticals As Composition
CA2706272C (en) 2010-06-03 2020-05-05 Accucaps Industries Limited Multi phase soft gel capsules, apparatus and method thereof

Also Published As

Publication number Publication date
EP2575787A4 (en) 2013-11-27
US20230233472A1 (en) 2023-07-27
EP3581173B1 (en) 2024-08-28
AU2011261117B2 (en) 2015-08-13
JP2013527205A (ja) 2013-06-27
EP2575787A1 (en) 2013-04-10
JP2016138143A (ja) 2016-08-04
EP2575787B1 (en) 2020-05-27
JP5972261B2 (ja) 2016-08-17
AU2011261117A1 (en) 2012-12-13
MX2012013933A (es) 2013-02-11
MX2019013095A (es) 2020-01-30
ES2807498T3 (es) 2021-02-23
HUE050830T2 (hu) 2021-01-28
CA2706270C (en) 2020-01-07
PL2575787T3 (pl) 2020-11-02
US11975108B2 (en) 2024-05-07
EP4445959A2 (en) 2024-10-16
EP3581173A1 (en) 2019-12-18
EP3581173C0 (en) 2024-08-28
US20130115281A1 (en) 2013-05-09
PT2575787T (pt) 2020-07-28
MX369477B (es) 2019-11-08
EP4445959A3 (en) 2025-01-08
CA2706270A1 (en) 2011-12-03
US12544341B2 (en) 2026-02-10
WO2011150505A1 (en) 2011-12-08

Similar Documents

Publication Publication Date Title
DK2575787T3 (da) Farmaceutiske formuleringer af statiner og omega-3-fedtsyrer til indkapsling
EP2846779A4 (en) STATIN AND OMEGA-3 FATTY ACID COMPOSITIONS
ZA201202263B (en) Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same
DK3527241T3 (da) Indretning til administration af lægemiddel
DK2525789T3 (da) Farmaceutiske formuleringer af naproxen til softgel-indkapsling og kombinationer deraf
LT3222272T (lt) Farmacinė karbetocino kompozicija
SMT201600350B (it) Composizioni farmaceutiche
DK3384902T3 (da) Fremgangsmåder, sammensætninger og indretninger til opfyldelse af diætmæssige behov for fedtsyre
PL2593090T3 (pl) Kompozycje farmaceutyczne modulatora c-Met
DK2498756T3 (da) Tabletformuleringer af neratinibmaleat
LT2603232T (lt) Stabilios linaklotido vaisto formos
DK2558133T3 (da) Coatinger til fremstillingen og anvendelse af polyhydroxyalkanoat-lægemiddelindretninger
DK3378862T3 (da) Dihydropyrimidinoisoquinolinoner og farmaceutiske sammensætninger deraf til behandlingen af multipel sklerose
DK3428290T3 (da) Sammensætninger og fremgangsmåder til amplifikation af nukleinsyrer
DK2596786T3 (da) Anvendelse af eicosapentaensyreethylester til behandling af hypertriglyceridæmi
EP2632272A4 (en) BIOACTIVE CHROMACTERIAL COMPOSITIONS AND METABOLITES THEREOF
DK2673262T3 (da) Fremgangsmåder til fremstilling af quinolinforbindelser og farmaceutiske sammensætninger indeholdende sådanne forbindelser
GT201200303A (es) Formulaciones farmacéuticas
SMT201400069B (it) Formulazione farmaceutica
DK2917358T3 (da) Sammensætninger og fremgangsmåder til biologisk fremstilling af fedtsyrederivater
SMT201400155B (it) Composizioni farmaceutiche comprendenti derivati di 2-osso-1-pirrolidina
PL2621477T3 (pl) Doustna tabletka farmaceutyczna do kontrolowanego uwalniania mesalazyny i sposób jej wytwarzania
IL225434A0 (en) Pharmaceutical compositions containing a dgat1 inhibitor
EP2408299A4 (en) FATTY ACID MONOGLYCERIDE COMPOSITIONS
DK2525827T3 (da) Farmaceutiske formuleringer af loratadin til indkapsling og kombinationer deraf