MX2019013095A - Formulaciones farmaceuticas de estatinas y acidos grasos omega-3 para encapsulacion. - Google Patents
Formulaciones farmaceuticas de estatinas y acidos grasos omega-3 para encapsulacion.Info
- Publication number
- MX2019013095A MX2019013095A MX2019013095A MX2019013095A MX2019013095A MX 2019013095 A MX2019013095 A MX 2019013095A MX 2019013095 A MX2019013095 A MX 2019013095A MX 2019013095 A MX2019013095 A MX 2019013095A MX 2019013095 A MX2019013095 A MX 2019013095A
- Authority
- MX
- Mexico
- Prior art keywords
- phase
- omega
- fatty acids
- dosage form
- statins
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- General Preparation And Processing Of Foods (AREA)
- Jellies, Jams, And Syrups (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Una forma de dosificación de gelatina blanda de múltiples fases que comprende por lo menos una forma de dosificación sólida preformada que comprende un compuesto de estatina y por lo menos una fase de relleno líquida que comprende ácidos grasos Omega-3. Las formas de dosificación de gelatina blanda de múltiples fases de la presente invención son especialmente útiles para combinar por lo menos una forma de dosificación sólida y por lo menos una fase líquida para una sola ingestión. La fase sólida, la fase líquida o los recubrimientos además pueden comprender ingredientes farmacéuticos activos, nutracéuticos, suplementos nutricionales, o sustancias terapéuticas, excipientes convencionales o combinaciones de los mismos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2706270A CA2706270C (en) | 2010-06-03 | 2010-06-03 | Pharmaceutical formulations of statins and omega-3 fatty acids for encapsulation |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019013095A true MX2019013095A (es) | 2020-01-30 |
Family
ID=45066009
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012013933A MX369477B (es) | 2010-06-03 | 2011-06-03 | Formulaciones farmacéuticas de estatinas y ácidos grasos omega-3 para encapsulación. |
MX2019013095A MX2019013095A (es) | 2010-06-03 | 2012-11-29 | Formulaciones farmaceuticas de estatinas y acidos grasos omega-3 para encapsulacion. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012013933A MX369477B (es) | 2010-06-03 | 2011-06-03 | Formulaciones farmacéuticas de estatinas y ácidos grasos omega-3 para encapsulación. |
Country Status (12)
Country | Link |
---|---|
US (2) | US11975108B2 (es) |
EP (2) | EP2575787B1 (es) |
JP (2) | JP5972261B2 (es) |
AU (1) | AU2011261117B2 (es) |
CA (1) | CA2706270C (es) |
DK (1) | DK2575787T3 (es) |
ES (1) | ES2807498T3 (es) |
HU (1) | HUE050830T2 (es) |
MX (2) | MX369477B (es) |
PL (1) | PL2575787T3 (es) |
PT (1) | PT2575787T (es) |
WO (1) | WO2011150505A1 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014095628A1 (en) * | 2012-12-17 | 2014-06-26 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Oral formulation containing a statin in omega-3 polyunsaturated fatty acids (n-3 pufa) |
MX2016004487A (es) | 2013-10-30 | 2016-11-10 | Banner Life Sciences Llc | Capsulas blandas de capa entérica que constan de ácidos grasos poli insaturados. |
US9326965B2 (en) | 2014-02-28 | 2016-05-03 | Banner Life Sciences Llc | Controlled release fumarate esters |
US9636318B2 (en) | 2015-08-31 | 2017-05-02 | Banner Life Sciences Llc | Fumarate ester dosage forms |
US10098863B2 (en) | 2014-02-28 | 2018-10-16 | Banner Life Sciences Llc | Fumarate esters |
US9326947B1 (en) | 2014-02-28 | 2016-05-03 | Banner Life Sciences Llc | Controlled release fumarate esters |
WO2015185240A1 (en) | 2014-06-04 | 2015-12-10 | Sigma-Tau Industrire Farmaceutiche Riunite S.P.A. | Compositions containing simvastatin in omega-3 polyunsaturated fatty acids |
US9895333B2 (en) | 2014-06-26 | 2018-02-20 | Patheon Softgels Inc. | Enhanced bioavailability of polyunsaturated fatty acids |
WO2015200563A1 (en) * | 2014-06-26 | 2015-12-30 | Banner Life Sciences Llc | Enhanced bioavailability of polysaturated fatty acids |
WO2016024844A1 (ko) * | 2014-08-13 | 2016-02-18 | 한국유나이티드제약 주식회사 | 오메가-3 지방산 에스테르 및 스타틴계 약물을 포함하는 경구용 복합제제 |
KR101950907B1 (ko) * | 2016-02-05 | 2019-02-21 | 한국유나이티드제약 주식회사 | 지용성 약물 및 방유성 기제가 코팅된 고형제제를 포함하는 경구용 복합제제 |
WO2017171484A1 (ko) * | 2016-03-31 | 2017-10-05 | 한미약품 주식회사 | 오메가-3 지방산 또는 이의 에스테르, 및 하이드록시메틸글루타릴 코엔자임에이 환원효소 억제제를 포함하는 경구용 복합 제제 |
US11547693B2 (en) | 2019-07-29 | 2023-01-10 | Matthias Rath | Ascorbate in the prevention of statin induced vascular calcification |
US10736872B1 (en) * | 2019-09-05 | 2020-08-11 | Matthias W. Rath | Pharmaceutical mixture to treat statin induced vascular calcification |
US11903918B2 (en) | 2020-01-10 | 2024-02-20 | Banner Life Sciences Llc | Fumarate ester dosage forms with enhanced gastrointestinal tolerability |
BR102021011153B1 (pt) | 2021-06-09 | 2022-12-27 | Fernando Campos Barbosa | Composição fitoterápica associada a suplementos polivitamínicos e minerais |
Family Cites Families (32)
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US1803440A (en) * | 1929-07-25 | 1931-05-05 | Newspaper Mechanical Sales Com | Coin control for vending machines |
US2775080A (en) | 1950-05-26 | 1956-12-25 | American Cyanamid Co | Method of forming powder-and-liquid filled capsules |
US2711814A (en) * | 1953-08-14 | 1955-06-28 | Bartlett And Company Grain | Apparatus for cleaning flat bottom grain tanks |
US3536074A (en) | 1968-03-29 | 1970-10-27 | Alfred Aufhauser | Oral administration of a pill,tablet or capsule |
US4655027A (en) | 1980-11-24 | 1987-04-07 | Chasman Sydney A | Method and apparatus for forming capsules |
RU2134105C1 (ru) * | 1993-06-18 | 1999-08-10 | Смитклайн Бичам Корпорейшн | Мягкая желатиновая капсула |
NZ520176A (en) * | 1997-07-31 | 2005-02-25 | Kos Life Sciences Inc | Combinations of HMG-CoA reductase inhibitors and nicotinic acid compounds and methods for treating hyperlipidemia once a day at night |
US6238616B1 (en) | 1998-12-14 | 2001-05-29 | Timecaps Inc. | Method of manufacturing gelatin capsule containing powder or time release pellets |
US6574945B2 (en) | 2001-03-21 | 2003-06-10 | Lumitek Llc | Method for manufacturing a projectile containing chemiluminescent compounds |
DE60219307T2 (de) * | 2001-06-12 | 2008-01-10 | Galephar M/F | Oral anzuwendende arzneizusammensetzung enthaltend ein statinderivat |
WO2004000731A2 (en) | 2002-06-25 | 2003-12-31 | Akzo Nobel N.V. | Use of cationic layered materials, compositions comprising these materials, and the preparation of cationic layered materials |
FR2850275B1 (fr) * | 2003-01-24 | 2005-04-08 | Scherer Technologies Inc R P | Capsules molles a macher contenant une substance active a gout masque |
US20040146537A1 (en) * | 2003-01-28 | 2004-07-29 | Ramachandran Radhakrishnan | Oily wax matrix suspension formulation comprising pharmacologically active agents |
CA2475765A1 (en) * | 2003-07-29 | 2005-01-29 | L. Perrigo Company | Tablet encapsulating machine |
CN1852894A (zh) * | 2003-09-17 | 2006-10-25 | 沃尼尔·朗伯有限责任公司 | [R-(R*, R*)]-2-(4-氟苯基) -β,δ-二羟基-5-(1-甲基乙基) -3-苯基-4-[(苯基氨基)羰基] -1 H-吡咯-1-庚酸的结晶形式 |
ES2255426B1 (es) * | 2004-10-19 | 2007-08-16 | Gp Pharm, S.A. | Formulacion farmaceutica que comprende microcapsulas de estatinas suspendidas en ester alquilicos de acidos grasos poliinsaturados (pufa). |
US20070191467A1 (en) * | 2004-12-06 | 2007-08-16 | Reliant Pharmaceutical, Inc. | Statin and omega-3 fatty acids for lipid therapy |
MX2007011031A (es) * | 2005-03-08 | 2008-04-21 | Reliant Pharmaceuticals Inc | Tratamiento con estatina y acidos grasos omega-3 y un producto de combinacion de los mismos. |
US7887852B2 (en) * | 2005-06-03 | 2011-02-15 | Soft Gel Technologies, Inc. | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols |
WO2006136196A1 (en) * | 2005-06-21 | 2006-12-28 | V. Mane Fils | Gellan seamless breakable capsule and process for manufacturing thereof |
CA2634139C (en) * | 2005-12-20 | 2015-06-23 | Cenestra, Llc. | Omega 3 fatty acid formulations |
EP2081550B2 (en) * | 2006-03-09 | 2021-05-26 | Reliant Pharmaceuticals, Inc. | Coating capsules with active pharmaceutical ingredients |
US8784886B2 (en) | 2006-03-09 | 2014-07-22 | GlaxoSmithKline, LLC | Coating capsules with active pharmaceutical ingredients |
US20070218141A1 (en) * | 2006-03-15 | 2007-09-20 | Ashis Kumar Mehta | Simvastatin compositions |
US20100310650A1 (en) * | 2006-06-26 | 2010-12-09 | Roberto Valducci | Pharmaceutical composition for the oral administration of omega polyenoic fatty acids and one or more active principles incompatible therewith, and a process for its preparation |
US8481084B2 (en) * | 2007-05-23 | 2013-07-09 | Amcol International Corporation | Cholesterol-interacting layered phyllosilicates and methods of reducing hypercholesteremia in a mammal |
ITMI20072142A1 (it) * | 2007-11-08 | 2009-05-09 | Yervant Zarmanian | Composizioni farmaceutiche contenenti statine e derivati di acidi grassi omega-3 |
US20100285121A1 (en) * | 2008-01-10 | 2010-11-11 | Takeda Pharmaceutical Company Limited | Capsule Formulation |
US20110082119A1 (en) * | 2008-06-13 | 2011-04-07 | Takashi Yano | Prophylactic/ameliorating or therapeutic agent for non-alcoholic steatohepatitis |
US20100062057A1 (en) * | 2008-09-10 | 2010-03-11 | Pronova BioPharma Norge AS. | Formulation |
GB0818472D0 (en) * | 2008-10-08 | 2008-11-12 | Probio Nutraceuticals As | Composition |
CA2706272C (en) | 2010-06-03 | 2020-05-05 | Accucaps Industries Limited | Multi phase soft gel capsules, apparatus and method thereof |
-
2010
- 2010-06-03 CA CA2706270A patent/CA2706270C/en active Active
-
2011
- 2011-06-03 EP EP11789014.5A patent/EP2575787B1/en active Active
- 2011-06-03 US US13/701,463 patent/US11975108B2/en active Active
- 2011-06-03 EP EP19189074.8A patent/EP3581173A1/en active Pending
- 2011-06-03 JP JP2013512707A patent/JP5972261B2/ja active Active
- 2011-06-03 PT PT117890145T patent/PT2575787T/pt unknown
- 2011-06-03 DK DK11789014.5T patent/DK2575787T3/da active
- 2011-06-03 AU AU2011261117A patent/AU2011261117B2/en active Active
- 2011-06-03 WO PCT/CA2011/000650 patent/WO2011150505A1/en active Application Filing
- 2011-06-03 HU HUE11789014A patent/HUE050830T2/hu unknown
- 2011-06-03 ES ES11789014T patent/ES2807498T3/es active Active
- 2011-06-03 MX MX2012013933A patent/MX369477B/es active IP Right Grant
- 2011-06-03 PL PL11789014T patent/PL2575787T3/pl unknown
-
2012
- 2012-11-29 MX MX2019013095A patent/MX2019013095A/es unknown
-
2016
- 2016-05-06 JP JP2016093142A patent/JP2016138143A/ja active Pending
-
2023
- 2023-04-03 US US18/130,142 patent/US20230233472A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3581173A1 (en) | 2019-12-18 |
AU2011261117B2 (en) | 2015-08-13 |
WO2011150505A1 (en) | 2011-12-08 |
CA2706270C (en) | 2020-01-07 |
EP2575787A1 (en) | 2013-04-10 |
HUE050830T2 (hu) | 2021-01-28 |
MX2012013933A (es) | 2013-02-11 |
US20230233472A1 (en) | 2023-07-27 |
US11975108B2 (en) | 2024-05-07 |
CA2706270A1 (en) | 2011-12-03 |
PT2575787T (pt) | 2020-07-28 |
US20130115281A1 (en) | 2013-05-09 |
AU2011261117A1 (en) | 2012-12-13 |
MX369477B (es) | 2019-11-08 |
EP2575787A4 (en) | 2013-11-27 |
DK2575787T3 (da) | 2020-08-03 |
JP5972261B2 (ja) | 2016-08-17 |
JP2013527205A (ja) | 2013-06-27 |
PL2575787T3 (pl) | 2020-11-02 |
ES2807498T3 (es) | 2021-02-23 |
JP2016138143A (ja) | 2016-08-04 |
EP2575787B1 (en) | 2020-05-27 |
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