MX369409B - Método para la fabricación de un producto perfilado de ácido hialurónico. - Google Patents
Método para la fabricación de un producto perfilado de ácido hialurónico.Info
- Publication number
- MX369409B MX369409B MX2015017526A MX2015017526A MX369409B MX 369409 B MX369409 B MX 369409B MX 2015017526 A MX2015017526 A MX 2015017526A MX 2015017526 A MX2015017526 A MX 2015017526A MX 369409 B MX369409 B MX 369409B
- Authority
- MX
- Mexico
- Prior art keywords
- hyaluronic acid
- cross
- shaped cross
- acid product
- manufacturing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F9/00—Artificial filaments or the like of other substances; Manufacture thereof; Apparatus specially adapted for the manufacture of carbon filaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/91—Injection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Birds (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Dispersion Chemistry (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Textile Engineering (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Inorganic Chemistry (AREA)
Abstract
La presente invención se refiere a un método para fabricar un producto perfilado de ácido hialurónico entrelazado que comprende el paso de someter un sustrato de ácido hialurónico, precipitado, no entrelazado en un perfil deseado a una única reacción de entrelazamiento en un medio líquido que tiene un pH de 11.5 o superior y que comprende uno o más agentes de entrelazado polifuncionales y una cantidad de uno o más solventes orgánicos que dan condiciones precipitantes para el ácido hialurónico, bajo condiciones adecuadas para obtener un producto perfilado, precipitado de ácido hialurónico entrelazado que tiene un grado de modificación de 1-40 de unidades de agente de entrelazado por 1000 unidades de disacáridos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2013/063716 WO2014206500A1 (en) | 2013-06-28 | 2013-06-28 | Method for manufacturing a shaped cross-linked hyaluronic acid product |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015017526A MX2015017526A (es) | 2016-08-05 |
MX369409B true MX369409B (es) | 2019-11-07 |
Family
ID=48703545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015017526A MX369409B (es) | 2013-06-28 | 2013-06-28 | Método para la fabricación de un producto perfilado de ácido hialurónico. |
Country Status (12)
Country | Link |
---|---|
US (4) | US10077321B2 (es) |
EP (2) | EP3013865B1 (es) |
JP (1) | JP6434003B2 (es) |
KR (1) | KR102048395B1 (es) |
CN (2) | CN109734825B (es) |
AU (1) | AU2013396752B2 (es) |
BR (1) | BR112015031589A2 (es) |
CA (1) | CA2916119A1 (es) |
HK (1) | HK1224314A1 (es) |
MX (1) | MX369409B (es) |
RU (1) | RU2640865C2 (es) |
WO (1) | WO2014206500A1 (es) |
Families Citing this family (23)
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US20210402050A1 (en) * | 2020-06-24 | 2021-12-30 | Anika Therapeutics, Inc. | Composite medical textile with non-resorbable fibers and bioresorbable hyaluronan-based fibers |
CN107207784B (zh) * | 2015-02-13 | 2022-08-23 | (株)安道德玛 | 利用交联透明质酸水凝胶的微结构体及其的制造方法 |
EP3328351A1 (en) | 2015-07-27 | 2018-06-06 | Galderma S.A. | A process for efficient cross-linking of hyaluronic acid |
KR101709608B1 (ko) * | 2015-09-03 | 2017-03-09 | (주)진우바이오 | 용융 방사에 의한 히알루론산염 파이버의 제조방법 및 이로부터 제조된 히알루론산염 파이버 |
US20170081491A1 (en) * | 2015-09-18 | 2017-03-23 | Arkema Inc. | Polyol pre-mixes having improved shelf life |
KR20170090965A (ko) | 2016-01-29 | 2017-08-08 | 한미약품 주식회사 | 복합 히알루론산 가교물 및 그 제조방법 |
US20190247547A1 (en) * | 2016-10-18 | 2019-08-15 | Aarhus Universitet | Printed hyaluronic acid scaffolds |
WO2018122343A1 (en) | 2016-12-29 | 2018-07-05 | Nestlé Skin Health Sa | Micro- or nanoparticular vesicles comprising crosslinked hyaluronic acid, compositions comprising the same and method for their use in skin care |
WO2018122342A1 (en) * | 2016-12-29 | 2018-07-05 | Nestlé Skin Health Sa | Micro- or nanoparticular multilamellar vesicles, compositions comprising the same and method for their use in skin care |
EP3562470A1 (en) | 2016-12-29 | 2019-11-06 | Nestlé Skin Health SA | Composition comprising a crosslinked hyaluronic acid (ha) in combination with a low-molecular ha and/or an agent stimulating endogenous ha synthesis |
CA3055985A1 (en) | 2017-03-22 | 2018-09-27 | Genentech, Inc. | Hydrogel cross-linked hyaluronic acid prodrug compositions and methods |
WO2019073364A1 (en) * | 2017-10-12 | 2019-04-18 | Solyplus Berlin Gmbh | CROSSLINKING BIOPOLYMERS IN A SEMI-SOLID STATE |
US20220160934A1 (en) * | 2019-03-24 | 2022-05-26 | Allergan Pharmaceuticals International Limited | Injectable homogeneous gels comprising multiple forms of hyaluronic acid and methods for manufacturing thereof |
WO2020234167A1 (en) * | 2019-05-17 | 2020-11-26 | ETH Zürich | Printable hydrogel, method for generating a printable hydrogel, lyophilizate, printed product and 3d printing method |
CN112147029A (zh) * | 2019-06-28 | 2020-12-29 | 杭州协合医疗用品有限公司 | 一种交联透明质酸钠凝胶溶胀度的测定方法 |
EP3995530A4 (en) * | 2019-09-27 | 2022-08-31 | LG Chem, Ltd. | METHOD FOR PREPARING POLYMERIC MICROPARTICLES, POLYMERIC MICROPARTICLES, MEDICAL COMPOSITION COMPRISING THEM, COSMETIC COMPOSITION, MEDICAL ARTICLE AND COSMETIC ARTICLE |
KR102173790B1 (ko) * | 2020-02-26 | 2020-11-03 | (주) 제이피케어즈 | 가교 히알루론산을 이용한 약물 전달 조성물 및 이의 제조방법 |
EP4253614A1 (en) * | 2020-11-26 | 2023-10-04 | Jinwoo Bio Co., Ltd. | Hyaluronate fiber and manufacturing method therefor |
KR102527095B1 (ko) | 2020-12-18 | 2023-04-28 | 충남대학교산학협력단 | 가교 처리된 히알루론산 조성물의 가교율 측정방법 |
CN113045779B (zh) * | 2021-03-22 | 2022-09-02 | 华熙生物科技股份有限公司 | 一种交联透明质酸凝胶粗品及其制备方法 |
EP4415771A1 (en) * | 2021-10-15 | 2024-08-21 | Prohibix LLC | Crosslinked hyaluronic acid precipitates |
CN114404355B (zh) * | 2021-12-28 | 2024-05-24 | 常州药物研究所有限公司 | 透明质酸钠凝胶及其制备方法、应用 |
WO2023148619A1 (en) | 2022-02-01 | 2023-08-10 | Galderma Holding SA | Methods of producing crosslinked hyaluronic acid hydrogels |
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US4605691A (en) * | 1984-12-06 | 1986-08-12 | Biomatrix, Inc. | Cross-linked gels of hyaluronic acid and products containing such gels |
US4582865A (en) * | 1984-12-06 | 1986-04-15 | Biomatrix, Inc. | Cross-linked gels of hyaluronic acid and products containing such gels |
AU619760B2 (en) | 1987-12-10 | 1992-02-06 | Genzyme Biosurgery Corporation | Hylan preparation and method of recovery thereof from animal tissues |
JPH01197501A (ja) | 1988-02-02 | 1989-08-09 | Mitsubishi Acetate Co Ltd | 精製サイリウムガムの製造方法 |
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GB9902412D0 (en) * | 1999-02-03 | 1999-03-24 | Fermentech Med Ltd | Process |
TW574301B (en) * | 2001-05-02 | 2004-02-01 | Ind Tech Res Inst | Manufacturing method of epoxide crosslinked polysaccharides matrix |
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US7323425B2 (en) * | 2004-08-27 | 2008-01-29 | Stony Brook Technology And Applied Research | Crosslinking of hyaluronan solutions and nanofiberous membranes made therefrom |
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EP2459239A1 (en) * | 2009-07-30 | 2012-06-06 | Carbylan Biosurgery, Inc. | Modified hyaluronic acid polymer compositions and related methods |
ES2645860T3 (es) * | 2010-10-20 | 2017-12-11 | Allergan Holdings France S.A.S. | Hilos de ácido hialurónico reticulado y uso de los mismos |
CZ302994B6 (cs) * | 2010-12-31 | 2012-02-08 | Cpn S.R.O. | Hyaluronová vlákna, zpusob jejich prípravy a použití |
CN102552974A (zh) * | 2012-02-17 | 2012-07-11 | 上海白衣缘生物工程有限公司 | 皮肤注射填充用凝胶组合物及其制备 |
CN102660040B (zh) * | 2012-05-03 | 2014-03-12 | 杭州协合医疗用品有限公司 | 一种透明质酸钠凝胶的制备方法 |
CN102731801B (zh) * | 2012-07-13 | 2013-12-25 | 常州药物研究所有限公司 | 外科整形用交联透明质酸钠凝胶及其制备方法 |
CN102863631B (zh) * | 2012-09-29 | 2013-11-13 | 杭州嘉伟生物制品有限公司 | 外科整形用组织填充剂交联透明质酸钠凝胶及其制备方法 |
-
2013
- 2013-06-28 CN CN201910026542.9A patent/CN109734825B/zh active Active
- 2013-06-28 EP EP13732529.6A patent/EP3013865B1/en active Active
- 2013-06-28 CA CA2916119A patent/CA2916119A1/en not_active Abandoned
- 2013-06-28 JP JP2016522286A patent/JP6434003B2/ja not_active Expired - Fee Related
- 2013-06-28 RU RU2016101734A patent/RU2640865C2/ru not_active IP Right Cessation
- 2013-06-28 EP EP19202714.2A patent/EP3617236B1/en active Active
- 2013-06-28 AU AU2013396752A patent/AU2013396752B2/en not_active Ceased
- 2013-06-28 US US14/901,546 patent/US10077321B2/en active Active
- 2013-06-28 BR BR112015031589A patent/BR112015031589A2/pt not_active Application Discontinuation
- 2013-06-28 WO PCT/EP2013/063716 patent/WO2014206500A1/en active Application Filing
- 2013-06-28 MX MX2015017526A patent/MX369409B/es active IP Right Grant
- 2013-06-28 CN CN201380079033.3A patent/CN105473622B/zh active Active
- 2013-06-28 KR KR1020167002526A patent/KR102048395B1/ko active IP Right Grant
-
2016
- 2016-11-03 HK HK16112650.8A patent/HK1224314A1/zh unknown
-
2018
- 2018-08-24 US US16/111,561 patent/US20180362670A1/en not_active Abandoned
-
2020
- 2020-02-04 US US16/781,264 patent/US10982016B2/en active Active
-
2021
- 2021-03-29 US US17/216,084 patent/US11702484B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
AU2013396752A1 (en) | 2016-02-18 |
US20200247913A1 (en) | 2020-08-06 |
US20180362670A1 (en) | 2018-12-20 |
BR112015031589A2 (pt) | 2017-07-25 |
RU2640865C2 (ru) | 2018-01-12 |
EP3617236B1 (en) | 2024-07-31 |
US11702484B2 (en) | 2023-07-18 |
JP6434003B2 (ja) | 2018-12-05 |
US20160145357A1 (en) | 2016-05-26 |
CN109734825A (zh) | 2019-05-10 |
US10982016B2 (en) | 2021-04-20 |
CN105473622B (zh) | 2019-01-29 |
EP3013865B1 (en) | 2019-10-23 |
AU2013396752B2 (en) | 2018-11-08 |
CN105473622A (zh) | 2016-04-06 |
HK1224314A1 (zh) | 2017-08-18 |
EP3617236A1 (en) | 2020-03-04 |
WO2014206500A1 (en) | 2014-12-31 |
KR20160027095A (ko) | 2016-03-09 |
JP2016524016A (ja) | 2016-08-12 |
KR102048395B1 (ko) | 2019-11-25 |
CA2916119A1 (en) | 2014-12-31 |
US10077321B2 (en) | 2018-09-18 |
US20210214468A1 (en) | 2021-07-15 |
RU2016101734A (ru) | 2017-08-02 |
EP3013865A1 (en) | 2016-05-04 |
CN109734825B (zh) | 2022-01-28 |
MX2015017526A (es) | 2016-08-05 |
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