MX358408B - Ensayos interrogatorios basados en celulas y usos de los mismos. - Google Patents
Ensayos interrogatorios basados en celulas y usos de los mismos.Info
- Publication number
- MX358408B MX358408B MX2013010068A MX2013010068A MX358408B MX 358408 B MX358408 B MX 358408B MX 2013010068 A MX2013010068 A MX 2013010068A MX 2013010068 A MX2013010068 A MX 2013010068A MX 358408 B MX358408 B MX 358408B
- Authority
- MX
- Mexico
- Prior art keywords
- biological system
- data set
- model
- obtaining
- based assays
- Prior art date
Links
Classifications
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
- G16B5/20—Probabilistic models
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Evolutionary Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Genetics & Genomics (AREA)
- Probability & Statistics with Applications (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Mobile Radio Communication Systems (AREA)
- Medical Treatment And Welfare Office Work (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Abstract
La presente invención se refiere a una Tecnología de Plataforma de descubrimiento para analizar un sistema o proceso biológico (por ejemplo, una enfermedad, tal como cáncer) por medio de un modelo de construcción. En particular, se describe en la presente un método para identificar un modulador de un sistema biológico mediante el establecimiento de un modelo para el sistema biológico, obtener un primer conjunto de datos del modelo para el sistema biológico, obtener un segundo conjunto de datos del modelo para el sistema biológico, y generar una red de relaciones causales de consenso entre los niveles de expresión de la pluralidad de genes y la actividad funcional o la respuesta celular basada únicamente en el primer conjunto de datos y el segundo conjunto de datos, usando un dispositivo informático programado.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161448587P | 2011-03-02 | 2011-03-02 | |
| US201261593848P | 2012-02-01 | 2012-02-01 | |
| PCT/US2012/027615 WO2012119129A1 (en) | 2011-03-02 | 2012-03-02 | Interrogatory cell-based assays and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013010068A MX2013010068A (es) | 2013-11-01 |
| MX358408B true MX358408B (es) | 2018-08-20 |
Family
ID=46758320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013010068A MX358408B (es) | 2011-03-02 | 2012-03-02 | Ensayos interrogatorios basados en celulas y usos de los mismos. |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US9886545B2 (es) |
| EP (1) | EP2680925B1 (es) |
| JP (2) | JP6105491B2 (es) |
| KR (1) | KR102071081B1 (es) |
| CN (2) | CN103501859B (es) |
| AU (2) | AU2012223136B2 (es) |
| BR (1) | BR112013022208A2 (es) |
| CA (1) | CA2828972C (es) |
| CL (2) | CL2013002526A1 (es) |
| CO (1) | CO6801640A2 (es) |
| EA (1) | EA201391245A1 (es) |
| ES (1) | ES2777894T3 (es) |
| IL (2) | IL228096B (es) |
| MX (1) | MX358408B (es) |
| MY (2) | MY181093A (es) |
| PE (2) | PE20180776A1 (es) |
| PH (2) | PH12017502072A1 (es) |
| SG (2) | SG193006A1 (es) |
| WO (1) | WO2012119129A1 (es) |
| ZA (1) | ZA201306453B (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11694765B2 (en) | 2012-05-22 | 2023-07-04 | Berg Llc | Interrogatory cell-based assays for identifying drug-induced toxicity markers |
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| ES2551922T3 (es) | 2011-03-07 | 2015-11-24 | Accelerate Diagnostics, Inc. | Sistemas rápidos de purificación celular |
| US10254204B2 (en) | 2011-03-07 | 2019-04-09 | Accelerate Diagnostics, Inc. | Membrane-assisted purification |
| CN104364393A (zh) * | 2012-03-05 | 2015-02-18 | 博格有限责任公司 | 用于诊断和治疗广泛性发育障碍的组合物和方法 |
| US9744155B2 (en) | 2012-03-28 | 2017-08-29 | Ixcela, Inc. | IPA as a therapeutic agent, as a protective agent, and as a biomarker of disease risk |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11694765B2 (en) | 2012-05-22 | 2023-07-04 | Berg Llc | Interrogatory cell-based assays for identifying drug-induced toxicity markers |
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