MX353550B - Uso de moleculas de enlace a semaforina-4d para la modulacion de la permeabilidad de la barrera sangre-cerebro. - Google Patents
Uso de moleculas de enlace a semaforina-4d para la modulacion de la permeabilidad de la barrera sangre-cerebro.Info
- Publication number
- MX353550B MX353550B MX2014004457A MX2014004457A MX353550B MX 353550 B MX353550 B MX 353550B MX 2014004457 A MX2014004457 A MX 2014004457A MX 2014004457 A MX2014004457 A MX 2014004457A MX 353550 B MX353550 B MX 353550B
- Authority
- MX
- Mexico
- Prior art keywords
- semaphorin
- brain barrier
- modulation
- barrier permeability
- binding molecules
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161545809P | 2011-10-11 | 2011-10-11 | |
| US201161555726P | 2011-11-04 | 2011-11-04 | |
| US201261593641P | 2012-02-01 | 2012-02-01 | |
| PCT/US2012/059757 WO2013055922A1 (en) | 2011-10-11 | 2012-10-11 | Use of semaphorin-4d binding molecules for modulation of blood brain barrier permeability |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014004457A MX2014004457A (es) | 2014-06-05 |
| MX353550B true MX353550B (es) | 2018-01-18 |
Family
ID=48082436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014004457A MX353550B (es) | 2011-10-11 | 2012-10-11 | Uso de moleculas de enlace a semaforina-4d para la modulacion de la permeabilidad de la barrera sangre-cerebro. |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20130095118A1 (https=) |
| EP (1) | EP2766093B1 (https=) |
| JP (2) | JP6395606B2 (https=) |
| KR (1) | KR101999872B1 (https=) |
| CN (2) | CN104168956A (https=) |
| AU (1) | AU2012322721B2 (https=) |
| BR (1) | BR112014008885B1 (https=) |
| CA (1) | CA2851805C (https=) |
| DK (1) | DK2766093T3 (https=) |
| EA (1) | EA029023B1 (https=) |
| ES (1) | ES2669209T3 (https=) |
| IL (1) | IL232072B (https=) |
| MX (1) | MX353550B (https=) |
| PT (1) | PT2766093T (https=) |
| SG (1) | SG11201401458UA (https=) |
| WO (1) | WO2013055922A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2647823T3 (es) | 2009-05-08 | 2017-12-26 | Vaccinex, Inc. | Anticuerpos anti-CD100 y métodos de uso de los mismos |
| US8790652B2 (en) | 2011-12-06 | 2014-07-29 | Vaccinex, Inc. | Use of the combination of semaphorin-4D inhibitory molecules and VEGF inhibitory molecules to inhibit angiogenesis |
| US9090709B2 (en) | 2012-03-28 | 2015-07-28 | Vaccinex, Inc. | Anti-SEMA4D antibodies and epitopes |
| US9708601B2 (en) | 2012-04-26 | 2017-07-18 | Vaccinex, Inc. | Fusion proteins to facilitate selection of cells infected with specific immunoglobulin gene recombinant vaccinia virus |
| US10494440B2 (en) | 2012-05-11 | 2019-12-03 | Vaccinex, Inc. | Use of semaphorin-4D binding molecules to promote neurogenesis following stroke |
| MX377858B (es) | 2013-06-25 | 2025-03-11 | Vaccinex Inc | Combinación de moleculas inhibidoras de semaforina-4d con agentes inmunomoduladores y usos de los mismos. |
| NZ630881A (en) | 2013-10-10 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treatment of atherosclerosis |
| NZ630892A (en) | 2013-10-21 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treating neurodegenerative disorders |
| US10973930B2 (en) | 2016-02-18 | 2021-04-13 | The Penn State Research Foundation | Generating GABAergic neurons in brains |
| IL262232B2 (en) | 2016-04-22 | 2024-06-01 | Vaccinex Inc | Integral membrane protein display on poxvirus extracellular enveloped virions |
| KR102449406B1 (ko) | 2016-08-02 | 2022-09-29 | 백시넥스 인코포레이티드 | 백시니아 바이러스/진핵 세포에서 폴리뉴클레오티드 라이브러리를 생산하기 위한 개선된 방법 |
| EP3512937B1 (en) * | 2016-09-13 | 2024-10-09 | Angiocrine Bioscience, Inc. | Blood-brain barrier comprising engineered endothelial cells |
| CN110325213A (zh) * | 2017-02-22 | 2019-10-11 | 瓦西尼斯公司 | 神经退行性或神经炎性疾病中胶质细胞活化的早期检测 |
| WO2018204895A1 (en) | 2017-05-05 | 2018-11-08 | Vaccinex, Inc. | Human anti-semaphorin 4d antibody |
| CA3076099A1 (en) * | 2017-09-22 | 2019-03-28 | Kite Pharma, Inc. | Linkers for chimeric antigen receptors |
| EP3746109A4 (en) * | 2018-02-02 | 2021-11-03 | The Penn State Research Foundation | METHODS AND MATERIALS FOR TREATING BRAIN INJURY |
| US20220090021A1 (en) * | 2019-01-22 | 2022-03-24 | Massachusetts Institute Of Technology | In vitro human blood brain barrier |
| JPWO2020202839A1 (https=) * | 2019-03-29 | 2020-10-08 | ||
| US11597765B2 (en) | 2020-06-25 | 2023-03-07 | Vaccinex, Inc. | Use of semaphorin-4D binding molecules for the treatment of Rett syndrome |
| EP3973979A1 (en) * | 2020-09-25 | 2022-03-30 | The Provost, Fellows, Foundation Scholars, and The Other Members of Board, of The College of The Holy and Undivided Trinity of Queen Elizabeth | A tight junction (zonulae occludentes) protein for use in treating or preventing epilepsy |
| CN113456813A (zh) * | 2021-07-26 | 2021-10-01 | 苏州大学 | Semaphorin7A单克隆抗体在制备用于治疗血栓及脑血管疾病药物方面的应用 |
| WO2023012314A1 (en) * | 2021-08-05 | 2023-02-09 | Lifearc | Anti-plexin-b1 antibodies |
| US20230101618A1 (en) * | 2021-09-27 | 2023-03-30 | Vaccinex, Inc. | Predictive outcome profiling for use of an anti-semaphorin-4d binding molecule to treat neurodegenerative disorders |
| CN114539204B (zh) * | 2022-03-23 | 2023-08-22 | 福建金兰厚普生物科技有限公司 | 己糖激酶抑制剂及其合成方法和应用 |
| AU2024247601A1 (en) * | 2023-03-28 | 2025-10-23 | Nb Health Laboratory Co., Ltd. | Antibody, nucleic acid, cell and drug |
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| NZ630881A (en) | 2013-10-10 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treatment of atherosclerosis |
| NZ630892A (en) | 2013-10-21 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treating neurodegenerative disorders |
| IL262232B2 (en) | 2016-04-22 | 2024-06-01 | Vaccinex Inc | Integral membrane protein display on poxvirus extracellular enveloped virions |
| KR102449406B1 (ko) | 2016-08-02 | 2022-09-29 | 백시넥스 인코포레이티드 | 백시니아 바이러스/진핵 세포에서 폴리뉴클레오티드 라이브러리를 생산하기 위한 개선된 방법 |
| CN110325213A (zh) | 2017-02-22 | 2019-10-11 | 瓦西尼斯公司 | 神经退行性或神经炎性疾病中胶质细胞活化的早期检测 |
-
2012
- 2012-10-11 BR BR112014008885-3A patent/BR112014008885B1/pt active IP Right Grant
- 2012-10-11 CN CN201280059376.9A patent/CN104168956A/zh active Pending
- 2012-10-11 DK DK12839601.7T patent/DK2766093T3/en active
- 2012-10-11 EA EA201490768A patent/EA029023B1/ru not_active IP Right Cessation
- 2012-10-11 AU AU2012322721A patent/AU2012322721B2/en active Active
- 2012-10-11 PT PT128396017T patent/PT2766093T/pt unknown
- 2012-10-11 MX MX2014004457A patent/MX353550B/es active IP Right Grant
- 2012-10-11 US US13/649,651 patent/US20130095118A1/en not_active Abandoned
- 2012-10-11 WO PCT/US2012/059757 patent/WO2013055922A1/en not_active Ceased
- 2012-10-11 ES ES12839601.7T patent/ES2669209T3/es active Active
- 2012-10-11 SG SG11201401458UA patent/SG11201401458UA/en unknown
- 2012-10-11 EP EP12839601.7A patent/EP2766093B1/en active Active
- 2012-10-11 KR KR1020147012547A patent/KR101999872B1/ko active Active
- 2012-10-11 JP JP2014535877A patent/JP6395606B2/ja active Active
- 2012-10-11 CN CN201910351743.6A patent/CN110105452A/zh active Pending
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|---|---|
| EP2766093A4 (en) | 2015-03-25 |
| NZ623856A (en) | 2016-04-29 |
| CA2851805A1 (en) | 2013-04-18 |
| AU2012322721A1 (en) | 2013-05-16 |
| EP2766093B1 (en) | 2018-02-21 |
| EP2766093A1 (en) | 2014-08-20 |
| US20130095118A1 (en) | 2013-04-18 |
| CA2851805C (en) | 2021-12-28 |
| MX2014004457A (es) | 2014-06-05 |
| KR101999872B1 (ko) | 2019-07-12 |
| BR112014008885B1 (pt) | 2021-02-17 |
| CN104168956A (zh) | 2014-11-26 |
| IL232072A0 (en) | 2014-05-28 |
| WO2013055922A1 (en) | 2013-04-18 |
| JP6395606B2 (ja) | 2018-09-26 |
| BR112014008885A2 (pt) | 2017-04-18 |
| SG11201401458UA (en) | 2014-07-30 |
| CN110105452A (zh) | 2019-08-09 |
| EA201490768A1 (ru) | 2014-09-30 |
| US20190358321A1 (en) | 2019-11-28 |
| ES2669209T3 (es) | 2018-05-24 |
| IL232072B (en) | 2021-01-31 |
| EA029023B1 (ru) | 2018-01-31 |
| JP2017193569A (ja) | 2017-10-26 |
| AU2012322721B2 (en) | 2016-05-05 |
| DK2766093T3 (en) | 2018-06-06 |
| JP2014530239A (ja) | 2014-11-17 |
| US11534488B2 (en) | 2022-12-27 |
| KR20140076616A (ko) | 2014-06-20 |
| PT2766093T (pt) | 2018-05-18 |
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