MX349718B - Compuestos antimicrobianos y metodos para fabricar y utilizar los mismos. - Google Patents
Compuestos antimicrobianos y metodos para fabricar y utilizar los mismos.Info
- Publication number
- MX349718B MX349718B MX2015017605A MX2015017605A MX349718B MX 349718 B MX349718 B MX 349718B MX 2015017605 A MX2015017605 A MX 2015017605A MX 2015017605 A MX2015017605 A MX 2015017605A MX 349718 B MX349718 B MX 349718B
- Authority
- MX
- Mexico
- Prior art keywords
- making
- methods
- same
- antimicrobial compounds
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Materials For Medical Uses (AREA)
Abstract
La presente invención se relaciona generalmente con el campo de los compuestos antimicrobianos y con los métodos de fabricación y uso de los mismos. Estos compuestos se utilizan para tratar, prevenir y reducir el riesgo de infecciones microbianas en los humanos y animales.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25247809P | 2009-10-16 | 2009-10-16 | |
US31428710P | 2010-03-16 | 2010-03-16 | |
US35820110P | 2010-06-24 | 2010-06-24 | |
PCT/US2010/052922 WO2011047319A2 (en) | 2009-10-16 | 2010-10-15 | Antimicrobial compounds and methods of making and using the same |
Publications (1)
Publication Number | Publication Date |
---|---|
MX349718B true MX349718B (es) | 2017-08-10 |
Family
ID=44343888
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015017605A MX349718B (es) | 2009-10-16 | 2010-10-15 | Compuestos antimicrobianos y metodos para fabricar y utilizar los mismos. |
MX2012004340A MX2012004340A (es) | 2009-10-16 | 2010-10-15 | Compuestos antimicrobianos y metodos para fabricar y utilizar los mismos. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012004340A MX2012004340A (es) | 2009-10-16 | 2010-10-15 | Compuestos antimicrobianos y metodos para fabricar y utilizar los mismos. |
Country Status (15)
Country | Link |
---|---|
US (2) | US9193731B2 (es) |
EP (2) | EP3406613A1 (es) |
JP (1) | JP6267863B2 (es) |
KR (2) | KR20190044136A (es) |
CN (1) | CN102712647B (es) |
AU (3) | AU2010306646B2 (es) |
CA (1) | CA2777734A1 (es) |
DK (1) | DK2488525T3 (es) |
EA (1) | EA201270566A1 (es) |
ES (1) | ES2675798T3 (es) |
IL (2) | IL219133A (es) |
MX (2) | MX349718B (es) |
NZ (1) | NZ599291A (es) |
PH (1) | PH12016502092A1 (es) |
WO (1) | WO2011047319A2 (es) |
Families Citing this family (39)
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WO2011047319A2 (en) | 2009-10-16 | 2011-04-21 | Rib-X Pharmaceuticals, Inc. | Antimicrobial compounds and methods of making and using the same |
EP2488532B1 (en) | 2009-10-16 | 2018-05-09 | Melinta Therapeutics, Inc. | Antimicrobial compounds and methods of making and using the same |
CA2777741A1 (en) | 2009-10-16 | 2011-04-21 | Rib-X Pharmaceuticals, Inc. | Antimicrobial compounds and methods of making and using the same |
EA201391536A1 (ru) * | 2011-04-15 | 2014-08-29 | Мелинта Терапьютикс, Инк. | Противомикробные соединения и способы их получения и применения |
CA2882879A1 (en) * | 2012-08-24 | 2014-02-27 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
SG11201601654TA (en) * | 2013-09-09 | 2016-04-28 | Melinta Therapeutics Inc | Antimicrobial compunds and methods of making and using the same |
WO2015035421A1 (en) | 2013-09-09 | 2015-03-12 | Melinta Therapeutics, Inc. | Antimicrobial compounds and methods of making and using the same |
WO2016028971A1 (en) | 2014-08-21 | 2016-02-25 | Bristol-Myers Squibb Company | Tied-back benzamide derivatives as potent rock inhibitors |
US10947237B2 (en) * | 2015-03-11 | 2021-03-16 | BioVersys AG | Antimicrobial compounds and methods of making and using the same |
TW201718581A (zh) | 2015-10-19 | 2017-06-01 | 英塞特公司 | 作為免疫調節劑之雜環化合物 |
ES2928856T3 (es) | 2015-11-19 | 2022-11-23 | Incyte Corp | Compuestos heterocíclicos como inmunomoduladores |
UA126113C2 (uk) | 2015-12-22 | 2022-08-17 | Інсайт Корпорейшн | Гетероциклічні сполуки як імуномодулятори |
EP3452479A1 (en) * | 2016-05-06 | 2019-03-13 | Melinta Therapeutics, Inc. | Antimicrobials and methods of making and using same |
WO2017193017A1 (en) | 2016-05-06 | 2017-11-09 | Melinta Therapeutics, Inc. | Antimicrobials and methods of making and using same |
WO2017192961A1 (en) | 2016-05-06 | 2017-11-09 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
WO2017193023A1 (en) * | 2016-05-06 | 2017-11-09 | Melinta Therapeutics, Inc. | Antimicrobials and methods of making and using same |
EP3464279B1 (en) | 2016-05-26 | 2021-11-24 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
WO2017222976A1 (en) | 2016-06-20 | 2017-12-28 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
WO2018013789A1 (en) | 2016-07-14 | 2018-01-18 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
MA46045A (fr) | 2016-08-29 | 2021-04-28 | Incyte Corp | Composés hétérocycliques utilisés comme immunomodulateurs |
ES2874756T3 (es) | 2016-12-22 | 2021-11-05 | Incyte Corp | Derivados de triazolo[1,5-A]piridina como inmunomoduladores |
AU2017382870B2 (en) | 2016-12-22 | 2022-03-24 | Incyte Corporation | Benzooxazole derivatives as immunomodulators |
US20180179179A1 (en) | 2016-12-22 | 2018-06-28 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
BR112019012957A2 (pt) | 2016-12-22 | 2019-11-26 | Incyte Corp | derivados de tetra-hidroimidazo[4,5-c]piridina como indutores de internalização de pd-l1 |
AU2018288665A1 (en) * | 2017-06-19 | 2019-12-19 | Ashoke Bhattacharjee | Antimicrobials and methods of making and using same |
US20210403473A1 (en) * | 2018-02-21 | 2021-12-30 | BioVersys AG | Antimicrobial compounds and methods of making and using the same |
SI3774791T1 (sl) | 2018-03-30 | 2023-04-28 | Incyte Corporation | Heterociklične spojine kot imunomodulatorji |
DK3790877T3 (da) | 2018-05-11 | 2023-04-24 | Incyte Corp | Tetrahydro-imidazo[4,5-c]pyridinderivater som pd-l1-immunmodulatorer |
US20210253577A1 (en) | 2018-06-06 | 2021-08-19 | BioVersys AG | Biodefense agents |
WO2019234509A2 (en) | 2018-06-06 | 2019-12-12 | BioVersys AG | Aminomethylamidine and methylamidine antimicrobial compounds |
IL279397B2 (en) * | 2018-06-15 | 2024-03-01 | Galapagos Nv | New compounds and their pharmaceutical preparations for the treatment of diseases |
WO2020115547A2 (en) * | 2018-12-07 | 2020-06-11 | BioVersys AG | Pyrrolo[2,3-d]pyrimidin-2-one antimicrobial compounds |
CA3150434A1 (en) | 2019-08-09 | 2021-02-18 | Incyte Corporation | Salts of a pd-1/pd-l1 inhibitor |
BR112022005826A2 (pt) | 2019-09-30 | 2022-06-21 | Incyte Corp | Compostos de pirido[3,2-d]pirimidina como imunomoduladores |
MX2022005651A (es) | 2019-11-11 | 2022-07-27 | Incyte Corp | Sales y formas cristalinas de un inhibidor de la proteina de muerte celular programada 1 (pd-1)/ligando de muerte celular programada 1 (pd-l1). |
AU2020384885A1 (en) * | 2019-11-13 | 2022-06-09 | Curza Global, Llc | Antimicrobial compounds and methods |
WO2022099018A1 (en) | 2020-11-06 | 2022-05-12 | Incyte Corporation | Process of preparing a pd-1/pd-l1 inhibitor |
JP2023548859A (ja) | 2020-11-06 | 2023-11-21 | インサイト・コーポレイション | Pd-1/pd-l1阻害剤ならびにその塩及び結晶形態を作製するためのプロセス |
US11760756B2 (en) | 2020-11-06 | 2023-09-19 | Incyte Corporation | Crystalline form of a PD-1/PD-L1 inhibitor |
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JP2012516321A (ja) | 2009-01-27 | 2012-07-19 | 武田薬品工業株式会社 | デルター5−デサチュラーゼ阻害薬 |
EP2501696B1 (en) | 2009-10-15 | 2016-12-28 | Guerbet | Imaging agents and their use for the diagnostic in vivo of neurodegenerative diseases, notably alzheimer's disease and derivative diseases |
WO2011047319A2 (en) | 2009-10-16 | 2011-04-21 | Rib-X Pharmaceuticals, Inc. | Antimicrobial compounds and methods of making and using the same |
EA201391536A1 (ru) | 2011-04-15 | 2014-08-29 | Мелинта Терапьютикс, Инк. | Противомикробные соединения и способы их получения и применения |
-
2010
- 2010-10-15 WO PCT/US2010/052922 patent/WO2011047319A2/en active Application Filing
- 2010-10-15 MX MX2015017605A patent/MX349718B/es unknown
- 2010-10-15 AU AU2010306646A patent/AU2010306646B2/en not_active Ceased
- 2010-10-15 JP JP2012534411A patent/JP6267863B2/ja not_active Expired - Fee Related
- 2010-10-15 KR KR1020197011312A patent/KR20190044136A/ko not_active Application Discontinuation
- 2010-10-15 ES ES10824203.3T patent/ES2675798T3/es active Active
- 2010-10-15 US US13/501,825 patent/US9193731B2/en active Active
- 2010-10-15 CN CN201080057335.7A patent/CN102712647B/zh not_active Expired - Fee Related
- 2010-10-15 KR KR1020177033784A patent/KR101972992B1/ko active IP Right Grant
- 2010-10-15 CA CA2777734A patent/CA2777734A1/en not_active Abandoned
- 2010-10-15 DK DK10824203.3T patent/DK2488525T3/en active
- 2010-10-15 EP EP18166144.8A patent/EP3406613A1/en not_active Withdrawn
- 2010-10-15 EP EP10824203.3A patent/EP2488525B1/en not_active Not-in-force
- 2010-10-15 MX MX2012004340A patent/MX2012004340A/es not_active Application Discontinuation
- 2010-10-15 EA EA201270566A patent/EA201270566A1/ru unknown
- 2010-10-15 NZ NZ599291A patent/NZ599291A/en not_active IP Right Cessation
-
2012
- 2012-04-15 IL IL219133A patent/IL219133A/en not_active IP Right Cessation
-
2015
- 2015-10-12 US US14/880,503 patent/US20160031893A1/en not_active Abandoned
-
2016
- 2016-10-20 PH PH12016502092A patent/PH12016502092A1/en unknown
- 2016-12-01 AU AU2016266048A patent/AU2016266048B2/en not_active Ceased
-
2017
- 2017-10-17 IL IL255097A patent/IL255097A0/en unknown
-
2018
- 2018-06-26 AU AU2018204628A patent/AU2018204628A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR20170132900A (ko) | 2017-12-04 |
AU2016266048A1 (en) | 2016-12-22 |
EA201270566A1 (ru) | 2012-11-30 |
PH12016502092A1 (en) | 2017-08-30 |
EP2488525B1 (en) | 2018-04-25 |
CN102712647A (zh) | 2012-10-03 |
DK2488525T3 (en) | 2018-08-06 |
JP6267863B2 (ja) | 2018-01-24 |
AU2010306646A1 (en) | 2012-05-03 |
CN102712647B (zh) | 2018-04-24 |
WO2011047319A3 (en) | 2011-08-18 |
MX2012004340A (es) | 2012-11-23 |
JP2013508297A (ja) | 2013-03-07 |
AU2010306646B2 (en) | 2016-09-01 |
EP2488525A2 (en) | 2012-08-22 |
AU2016266048B2 (en) | 2018-07-19 |
US9193731B2 (en) | 2015-11-24 |
KR20190044136A (ko) | 2019-04-29 |
EP2488525A4 (en) | 2013-07-03 |
AU2018204628A1 (en) | 2018-07-12 |
KR101972992B1 (ko) | 2019-04-29 |
IL219133A0 (en) | 2012-06-28 |
NZ599291A (en) | 2014-06-27 |
IL219133A (en) | 2017-10-31 |
CA2777734A1 (en) | 2011-04-21 |
EP3406613A1 (en) | 2018-11-28 |
ES2675798T3 (es) | 2018-07-12 |
WO2011047319A2 (en) | 2011-04-21 |
US20160031893A1 (en) | 2016-02-04 |
IL255097A0 (en) | 2017-12-31 |
US20120220566A1 (en) | 2012-08-30 |
WO2011047319A8 (en) | 2011-10-27 |
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