MX349718B - Compuestos antimicrobianos y metodos para fabricar y utilizar los mismos. - Google Patents

Compuestos antimicrobianos y metodos para fabricar y utilizar los mismos.

Info

Publication number
MX349718B
MX349718B MX2015017605A MX2015017605A MX349718B MX 349718 B MX349718 B MX 349718B MX 2015017605 A MX2015017605 A MX 2015017605A MX 2015017605 A MX2015017605 A MX 2015017605A MX 349718 B MX349718 B MX 349718B
Authority
MX
Mexico
Prior art keywords
making
methods
same
antimicrobial compounds
compounds
Prior art date
Application number
MX2015017605A
Other languages
English (en)
Inventor
Yusheng Wu
Ashoke Bhattacharjee
Hardwin Odowd
Erin M Duffy
Marco Devivo
Zoltan F Kanyo
Jacek G Martinow
Ik Hyeon Paik
Matthew H Scheideman
Sandra Sinishtaj
Brian T Winberly
Original Assignee
Melinta Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Melinta Therapeutics Inc filed Critical Melinta Therapeutics Inc
Publication of MX349718B publication Critical patent/MX349718B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Materials For Medical Uses (AREA)

Abstract

La presente invención se relaciona generalmente con el campo de los compuestos antimicrobianos y con los métodos de fabricación y uso de los mismos. Estos compuestos se utilizan para tratar, prevenir y reducir el riesgo de infecciones microbianas en los humanos y animales.
MX2015017605A 2009-10-16 2010-10-15 Compuestos antimicrobianos y metodos para fabricar y utilizar los mismos. MX349718B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25247809P 2009-10-16 2009-10-16
US31428710P 2010-03-16 2010-03-16
US35820110P 2010-06-24 2010-06-24
PCT/US2010/052922 WO2011047319A2 (en) 2009-10-16 2010-10-15 Antimicrobial compounds and methods of making and using the same

Publications (1)

Publication Number Publication Date
MX349718B true MX349718B (es) 2017-08-10

Family

ID=44343888

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2015017605A MX349718B (es) 2009-10-16 2010-10-15 Compuestos antimicrobianos y metodos para fabricar y utilizar los mismos.
MX2012004340A MX2012004340A (es) 2009-10-16 2010-10-15 Compuestos antimicrobianos y metodos para fabricar y utilizar los mismos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2012004340A MX2012004340A (es) 2009-10-16 2010-10-15 Compuestos antimicrobianos y metodos para fabricar y utilizar los mismos.

Country Status (15)

Country Link
US (2) US9193731B2 (es)
EP (2) EP3406613A1 (es)
JP (1) JP6267863B2 (es)
KR (2) KR20190044136A (es)
CN (1) CN102712647B (es)
AU (3) AU2010306646B2 (es)
CA (1) CA2777734A1 (es)
DK (1) DK2488525T3 (es)
EA (1) EA201270566A1 (es)
ES (1) ES2675798T3 (es)
IL (2) IL219133A (es)
MX (2) MX349718B (es)
NZ (1) NZ599291A (es)
PH (1) PH12016502092A1 (es)
WO (1) WO2011047319A2 (es)

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AU2017382870B2 (en) 2016-12-22 2022-03-24 Incyte Corporation Benzooxazole derivatives as immunomodulators
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AU2018288665A1 (en) * 2017-06-19 2019-12-19 Ashoke Bhattacharjee Antimicrobials and methods of making and using same
US20210403473A1 (en) * 2018-02-21 2021-12-30 BioVersys AG Antimicrobial compounds and methods of making and using the same
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DK3790877T3 (da) 2018-05-11 2023-04-24 Incyte Corp Tetrahydro-imidazo[4,5-c]pyridinderivater som pd-l1-immunmodulatorer
US20210253577A1 (en) 2018-06-06 2021-08-19 BioVersys AG Biodefense agents
WO2019234509A2 (en) 2018-06-06 2019-12-12 BioVersys AG Aminomethylamidine and methylamidine antimicrobial compounds
IL279397B2 (en) * 2018-06-15 2024-03-01 Galapagos Nv New compounds and their pharmaceutical preparations for the treatment of diseases
WO2020115547A2 (en) * 2018-12-07 2020-06-11 BioVersys AG Pyrrolo[2,3-d]pyrimidin-2-one antimicrobial compounds
CA3150434A1 (en) 2019-08-09 2021-02-18 Incyte Corporation Salts of a pd-1/pd-l1 inhibitor
BR112022005826A2 (pt) 2019-09-30 2022-06-21 Incyte Corp Compostos de pirido[3,2-d]pirimidina como imunomoduladores
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Also Published As

Publication number Publication date
KR20170132900A (ko) 2017-12-04
AU2016266048A1 (en) 2016-12-22
EA201270566A1 (ru) 2012-11-30
PH12016502092A1 (en) 2017-08-30
EP2488525B1 (en) 2018-04-25
CN102712647A (zh) 2012-10-03
DK2488525T3 (en) 2018-08-06
JP6267863B2 (ja) 2018-01-24
AU2010306646A1 (en) 2012-05-03
CN102712647B (zh) 2018-04-24
WO2011047319A3 (en) 2011-08-18
MX2012004340A (es) 2012-11-23
JP2013508297A (ja) 2013-03-07
AU2010306646B2 (en) 2016-09-01
EP2488525A2 (en) 2012-08-22
AU2016266048B2 (en) 2018-07-19
US9193731B2 (en) 2015-11-24
KR20190044136A (ko) 2019-04-29
EP2488525A4 (en) 2013-07-03
AU2018204628A1 (en) 2018-07-12
KR101972992B1 (ko) 2019-04-29
IL219133A0 (en) 2012-06-28
NZ599291A (en) 2014-06-27
IL219133A (en) 2017-10-31
CA2777734A1 (en) 2011-04-21
EP3406613A1 (en) 2018-11-28
ES2675798T3 (es) 2018-07-12
WO2011047319A2 (en) 2011-04-21
US20160031893A1 (en) 2016-02-04
IL255097A0 (en) 2017-12-31
US20120220566A1 (en) 2012-08-30
WO2011047319A8 (en) 2011-10-27

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