MX347170B - Cápsulas de dosis unitaria e inhalador de polvo seco. - Google Patents
Cápsulas de dosis unitaria e inhalador de polvo seco.Info
- Publication number
- MX347170B MX347170B MXPA02000812A MXPA02000812A MX347170B MX 347170 B MX347170 B MX 347170B MX PA02000812 A MXPA02000812 A MX PA02000812A MX PA02000812 A MXPA02000812 A MX PA02000812A MX 347170 B MX347170 B MX 347170B
- Authority
- MX
- Mexico
- Prior art keywords
- dry powder
- section
- mouthpiece
- intake
- powder inhaler
- Prior art date
Links
- 239000002775 capsule Substances 0.000 title abstract 3
- 229940112141 dry powder inhaler Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
- A61M15/0023—Mouthpieces therefor retractable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/04—Tracheal tubes
- A61M16/0488—Mouthpieces; Means for guiding, securing or introducing the tubes
- A61M16/049—Mouthpieces
- A61M16/0495—Mouthpieces with tongue depressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
- A61M16/0816—Joints or connectors
- A61M16/0825—Joints or connectors with ball-sockets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/07—General characteristics of the apparatus having air pumping means
- A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
- A61M2205/073—Syringe, piston type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/43—General characteristics of the apparatus making noise when used correctly
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/60—General characteristics of the apparatus with identification means
- A61M2205/6045—General characteristics of the apparatus with identification means having complementary physical shapes for indexing or registration purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nozzles (AREA)
- Package Specialized In Special Use (AREA)
Abstract
El inhalador de polvo seco (10) comprende una sección de entrada (20); una sección de mezclado (30), y una boquilla (40). La boquilla está conectada por medio de una junta giratoria a la sección de mezclado, y puede girar hacia atrás, hacia la sección de entrada y ser cerrada por una tapa o cubierta (290). La cámara de entrada comprende un pistón con una biela de pistón ahusada y un resorte, y uno o más orificios de purga para modular el flujo de aire a través del dispositivo. Opcionalmente comprende un módulo de retroalimentación para generar un tono que indique cuando ha sido alcanzada la velocidad de flujo apropiada. La sección de mezclado contiene una cápsula (300) con orificios que contienen un medicamento en forma de polvo seco y abre y cierra además la cápsula cuando la sección de entrada esté en un cierto ángulo con respecto a la boquilla. La sección de mezclado es una cámara de Venturi para impartir un flujo ciclónico al aire que pasa a través de la cámara de mezclado.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14546499P | 1999-07-23 | 1999-07-23 | |
| US20612300P | 2000-05-22 | 2000-05-22 | |
| PCT/US2000/040454 WO2001007107A2 (en) | 1999-07-23 | 2000-07-21 | Unit dose capsules and dry powder inhaler |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MXPA02000812A MXPA02000812A (es) | 2003-09-25 |
| MX347170B true MX347170B (es) | 2017-04-18 |
Family
ID=26843008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA02000812A MX347170B (es) | 1999-07-23 | 2000-07-21 | Cápsulas de dosis unitaria e inhalador de polvo seco. |
Country Status (15)
| Country | Link |
|---|---|
| EP (2) | EP1200149B1 (es) |
| JP (3) | JP2003508184A (es) |
| AT (2) | ATE390944T1 (es) |
| AU (1) | AU779693B2 (es) |
| BR (2) | BR0012718B1 (es) |
| CA (2) | CA2642084C (es) |
| CY (2) | CY1105860T1 (es) |
| DE (2) | DE60030862T2 (es) |
| DK (3) | DK1200149T3 (es) |
| ES (3) | ES2306002T3 (es) |
| IL (3) | IL147724A0 (es) |
| MX (1) | MX347170B (es) |
| NZ (1) | NZ516811A (es) |
| PT (2) | PT1649886E (es) |
| WO (1) | WO2001007107A2 (es) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US7464706B2 (en) * | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
| US7305986B1 (en) | 1999-07-23 | 2007-12-11 | Mannkind Corporation | Unit dose capsules for use in a dry powder inhaler |
| WO2002013897A2 (en) | 2000-08-14 | 2002-02-21 | Advanced Inhalation Research, Inc. | Inhalation device and method |
| US6595204B2 (en) * | 2001-03-01 | 2003-07-22 | Iep Pharmaceutical Devices Inc. | Spacer for an inhaler |
| US6766799B2 (en) | 2001-04-16 | 2004-07-27 | Advanced Inhalation Research, Inc. | Inhalation device |
| KR20040023597A (ko) * | 2001-05-10 | 2004-03-18 | 벡투라 딜리버리 디바이시스 리미티드 | 흡입기들 |
| WO2003048665A1 (en) | 2001-12-03 | 2003-06-12 | Massachusetts Institute Of Technology | Microscale lyophilization and drying methods for the stabilization of molecules |
| JP4681231B2 (ja) | 2002-03-20 | 2011-05-11 | マンカインド コーポレイション | 吸入装置 |
| GB0227128D0 (en) | 2002-11-20 | 2002-12-24 | Glaxo Group Ltd | A capsule |
| GB0308969D0 (en) | 2003-04-17 | 2003-05-28 | Glaxo Group Ltd | Capsules |
| AU2006225241B2 (en) * | 2003-09-24 | 2008-07-17 | Tianda Pharmaceuticals (Australia) Pty Limited | Medication Holder |
| EP1675636A4 (en) * | 2003-09-24 | 2009-12-23 | Medi Stream Pty Ltd | MEDICATION HOLDER |
| AU2004273547B2 (en) * | 2003-09-24 | 2006-07-06 | Tianda Pharmaceuticals (Australia) Pty Ltd | Medication holder |
| US7491194B1 (en) | 2004-02-03 | 2009-02-17 | David Oliwa | Remote control valve for urine collection bag |
| US20080090753A1 (en) | 2004-03-12 | 2008-04-17 | Biodel, Inc. | Rapid Acting Injectable Insulin Compositions |
| AU2005266789B2 (en) * | 2004-07-26 | 2010-11-25 | 1355540 Ontario Inc. | Powder inhaler featuring reduced compaction inhaler |
| ATE486064T1 (de) | 2004-08-20 | 2010-11-15 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
| HUE025151T2 (en) | 2004-08-23 | 2016-01-28 | Mannkind Corp | Diceto-piperazine salts for drug delivery |
| US8210171B2 (en) | 2004-09-13 | 2012-07-03 | Oriel Therapeutics, Inc. | Tubular dry powder drug containment systems, associated inhalers and methods |
| WO2006066363A1 (en) * | 2004-12-23 | 2006-06-29 | Acrux Dds Pty Ltd | Dispensing device |
| US8591457B2 (en) | 2005-08-10 | 2013-11-26 | Alza Corporation | Method for making a needle-free jet injection drug delivery device |
| MX373000B (es) | 2005-09-14 | 2020-05-21 | Mannkind Corp | Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas. |
| GB2433207B (en) * | 2006-02-21 | 2009-01-07 | Jianhe Li | Active suction actuated inhalers with timing devices |
| CN104383546B (zh) | 2006-02-22 | 2021-03-02 | 曼金德公司 | 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法 |
| EP1993645A4 (en) * | 2006-03-03 | 2011-05-18 | Stc Unm | DRY POWDER INHALER WITH AEROELASTIC SPREADING MECHANISM |
| EP1844806A1 (de) | 2006-04-13 | 2007-10-17 | Boehringer Ingelheim Pharma GmbH | Medikamenten-Ausgabevorrichtung, Medikamentenmagazin dafür, und Verfahren zur Entnahme eines Medikaments aus einer Medikamentenkammer |
| US8496002B2 (en) | 2007-06-12 | 2013-07-30 | Civitas Therapeutics, Inc. | Powder inhaler devices |
| EP2020249A1 (de) | 2007-08-01 | 2009-02-04 | Boehringer Ingelheim Pharma GmbH & Co. KG | Inhalator |
| HUE027246T2 (en) | 2008-01-24 | 2016-10-28 | Vectura Delivery Devices Ltd | inhaler |
| CA2719205C (en) * | 2008-03-27 | 2017-04-25 | Mannkind Corporation | A dry powder inhalation system |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| MY155524A (en) * | 2008-06-13 | 2015-10-30 | Mannkind Corp | A dry powder inhaler and system for drug delivery |
| EP2609954B1 (en) | 2008-06-20 | 2021-12-29 | MannKind Corporation | An interactive apparatus for real-time profiling of inhalation efforts |
| TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| US9060927B2 (en) | 2009-03-03 | 2015-06-23 | Biodel Inc. | Insulin formulations for rapid uptake |
| MX2011009251A (es) * | 2009-03-04 | 2011-11-18 | Mannkind Corp | Sistema mejorado de suministro de farmaco en polvo seco. |
| US8538707B2 (en) | 2009-03-11 | 2013-09-17 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| AU2010259943C1 (en) | 2009-06-12 | 2016-03-03 | Mannkind Corporation | Diketopiperazine microparticles with defined specific surface areas |
| JP5784622B2 (ja) | 2009-11-03 | 2015-09-24 | マンカインド コーポレ−ション | 吸入活動をシミュレートするための装置及び方法 |
| AU2010336338B2 (en) * | 2009-12-23 | 2015-02-19 | Map Pharmaceuticals, Inc. | Enhanced eductor design |
| RU2531455C2 (ru) | 2010-06-21 | 2014-10-20 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
| CN102553038B (zh) * | 2010-12-17 | 2014-07-02 | 陈庆堂 | 药粉吸嘴放置盒 |
| MX353285B (es) | 2011-04-01 | 2018-01-05 | Mannkind Corp | Paquete de blister para cartuchos farmaceuticos. |
| GB201107103D0 (en) * | 2011-04-27 | 2011-06-08 | Clement Clarke Int Ltd | Improvements in drug delivery inhaler devices |
| EP2707067A1 (de) * | 2011-05-12 | 2014-03-19 | Alfred Von Schuckmann | Vorrichtung zum inhalieren pulverförmiger substanzen |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| HK1201475A1 (en) | 2011-10-24 | 2015-09-04 | Mannkind Corporation | Methods and compositions for treating pain |
| WO2013114371A1 (en) | 2012-02-01 | 2013-08-08 | Protalix Ltd. | Dry powder formulations of dnase i |
| WO2013132497A1 (en) | 2012-03-07 | 2013-09-12 | Advanced Inhilation Therapies (Ait) Ltd. | Inhalation of nitric oxide for treating respiratory diseases |
| US9427534B2 (en) | 2012-07-05 | 2016-08-30 | Clement Clarke International Ltd. | Drug delivery inhaler devices |
| AU2013289957B2 (en) | 2012-07-12 | 2017-02-23 | Mannkind Corporation | Dry powder drug delivery systems and methods |
| WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
| CA151549S (en) | 2013-02-14 | 2014-06-04 | Clement Clarke Int Ltd | Spacer for an asthma inhaler |
| BR112015023168B1 (pt) | 2013-03-15 | 2021-08-10 | Mannkind Corporation | Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina |
| BR122019026637B1 (pt) | 2013-07-18 | 2023-09-26 | Mannkind Corporation | Formulações farmacêuticas de pó seco e método para a fabricação de uma formulação de pó seco |
| CA2920488C (en) | 2013-08-05 | 2022-04-26 | Mannkind Corporation | Insufflation apparatus and methods |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| DE102014017065B3 (de) * | 2014-11-20 | 2015-11-19 | Klaus-Dieter Beller | Pulverbehältnis für Pulverinhalatoren |
| CN107961432A (zh) * | 2017-11-16 | 2018-04-27 | 惠水县凡趣创意科技有限公司 | 一种胶囊送药器 |
| WO2019186372A1 (en) | 2018-03-26 | 2019-10-03 | Philip Morris Products S.A. | Inhaler with vortex capsule cavity |
| US12343470B2 (en) | 2019-01-14 | 2025-07-01 | Philip Morris Products S.A. | Dry powder inhaler |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE794951A (fr) * | 1972-02-03 | 1973-05-29 | Parke Davis & Co | Conditionnement soluble dans l'eau |
| DE2502251A1 (de) * | 1975-01-17 | 1976-07-22 | Schering Ag | Vorrichtung zur inhalation pulverfoermiger feststoffe |
| US4040536A (en) * | 1975-05-05 | 1977-08-09 | R. P. Scherer Corporation | Locking hard gelatin capsule |
| GB2072536B (en) * | 1980-03-25 | 1983-12-07 | Malem H | Nebuliser |
| US4487327A (en) * | 1982-12-21 | 1984-12-11 | Grayson Robert E | Locking capsule |
| CH661878A5 (de) * | 1983-11-04 | 1987-08-31 | Warner Lambert Co | Kapsel-dosierungsformen. |
| DE3639836A1 (de) * | 1986-11-21 | 1988-06-01 | Sigrid Bechter | Mundstueck fuer ein inhalationsgeraet |
| DE3727894A1 (de) * | 1987-08-21 | 1989-03-02 | Stephan Dieter | Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge |
| US4991605A (en) * | 1989-04-24 | 1991-02-12 | Philip Morris Incorporated | Container for additive materials for smoking articles |
| US5170801A (en) * | 1990-10-02 | 1992-12-15 | Glaxo Inc. | Medical capsule device actuated by radio-frequency (rf) signal |
| US5797391A (en) * | 1991-03-28 | 1998-08-25 | Rhone-Poulenc Rorer Limited | Inhaler |
| US5476093A (en) * | 1992-02-14 | 1995-12-19 | Huhtamaki Oy | Device for more effective pulverization of a powdered inhalation medicament |
| GB9216038D0 (en) * | 1992-07-28 | 1992-09-09 | Bespak Plc | Dispensing apparatus for powdered medicaments |
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| JP3545764B2 (ja) * | 1993-08-18 | 2004-07-21 | フアイソンズ・ピーエルシー | 吸息率制御器を備えた吸入装置 |
| US5524613A (en) * | 1993-08-25 | 1996-06-11 | Habley Medical Technology Corporation | Controlled multi-pharmaceutical inhaler |
| PT101450B (pt) * | 1994-02-02 | 1999-11-30 | Hovione Produtos Farmaceuticos | Novo dispositivo para inalacao |
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| JP3011898B2 (ja) * | 1997-02-20 | 2000-02-21 | フォルテ グロウ メディカル株式会社 | 吸引器 |
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| SE9700935D0 (sv) * | 1997-03-14 | 1997-03-14 | Astra Ab | Inhalation device |
-
2000
- 2000-07-21 AT AT05077995T patent/ATE390944T1/de active
- 2000-07-21 ES ES05077995T patent/ES2306002T3/es not_active Expired - Lifetime
- 2000-07-21 AT AT00960184T patent/ATE339981T1/de active
- 2000-07-21 IL IL14772400A patent/IL147724A0/xx unknown
- 2000-07-21 CA CA2642084A patent/CA2642084C/en not_active Expired - Fee Related
- 2000-07-21 EP EP00960184A patent/EP1200149B1/en not_active Expired - Lifetime
- 2000-07-21 MX MXPA02000812A patent/MX347170B/es active IP Right Grant
- 2000-07-21 PT PT05077995T patent/PT1649886E/pt unknown
- 2000-07-21 DK DK00960184T patent/DK1200149T3/da active
- 2000-07-21 CA CA002379137A patent/CA2379137C/en not_active Expired - Fee Related
- 2000-07-21 PT PT00960184T patent/PT1200149E/pt unknown
- 2000-07-21 ES ES08075104T patent/ES2395051T3/es not_active Expired - Lifetime
- 2000-07-21 DK DK05077995T patent/DK1649886T3/da active
- 2000-07-21 EP EP08075104A patent/EP1923087B1/en not_active Expired - Lifetime
- 2000-07-21 DE DE60030862T patent/DE60030862T2/de not_active Expired - Lifetime
- 2000-07-21 ES ES00960184T patent/ES2275544T3/es not_active Expired - Lifetime
- 2000-07-21 NZ NZ516811A patent/NZ516811A/xx not_active IP Right Cessation
- 2000-07-21 JP JP2001521942A patent/JP2003508184A/ja not_active Withdrawn
- 2000-07-21 DE DE60038511T patent/DE60038511T2/de not_active Expired - Lifetime
- 2000-07-21 BR BRPI0012718-3A patent/BR0012718B1/pt not_active IP Right Cessation
- 2000-07-21 DK DK08075104.3T patent/DK1923087T3/da active
- 2000-07-21 AU AU71380/00A patent/AU779693B2/en not_active Ceased
- 2000-07-21 BR BRPI0017519A patent/BR0017519B8/pt not_active IP Right Cessation
- 2000-07-21 WO PCT/US2000/040454 patent/WO2001007107A2/en not_active Ceased
-
2002
- 2002-01-17 IL IL147724A patent/IL147724A/en not_active IP Right Cessation
-
2005
- 2005-05-26 JP JP2005154727A patent/JP4608367B2/ja not_active Expired - Fee Related
-
2006
- 2006-12-19 CY CY20061101812T patent/CY1105860T1/el unknown
-
2007
- 2007-11-21 JP JP2007302168A patent/JP5055623B2/ja not_active Expired - Fee Related
- 2007-12-31 IL IL188519A patent/IL188519A/en not_active IP Right Cessation
-
2008
- 2008-06-02 CY CY20081100570T patent/CY1110253T1/el unknown
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