BR0012718A - Cápsulas de dose unitária e inalador de pó seco - Google Patents

Cápsulas de dose unitária e inalador de pó seco

Info

Publication number
BR0012718A
BR0012718A BR0012718-3A BR0012718A BR0012718A BR 0012718 A BR0012718 A BR 0012718A BR 0012718 A BR0012718 A BR 0012718A BR 0012718 A BR0012718 A BR 0012718A
Authority
BR
Brazil
Prior art keywords
section
nozzle
mixing section
mixing
dry powder
Prior art date
Application number
BR0012718-3A
Other languages
English (en)
Other versions
BR0012718B1 (pt
Inventor
Solomon S Steiner
Trent Poole
Robert Feldstein
Per B Fog
Original Assignee
Pharmaceutical Discovery Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmaceutical Discovery Corp filed Critical Pharmaceutical Discovery Corp
Priority to BRPI0017519A priority Critical patent/BR0017519B8/pt
Publication of BR0012718A publication Critical patent/BR0012718A/pt
Publication of BR0012718B1 publication Critical patent/BR0012718B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0023—Mouthpieces therefor retractable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A61M16/0488—Mouthpieces; Means for guiding, securing or introducing the tubes
    • A61M16/049—Mouthpieces
    • A61M16/0495—Mouthpieces with tongue depressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
    • A61M16/0816—Joints or connectors
    • A61M16/0825—Joints or connectors with ball-sockets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073—Syringe, piston type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/43—General characteristics of the apparatus making noise when used correctly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/60—General characteristics of the apparatus with identification means
    • A61M2205/6045—General characteristics of the apparatus with identification means having complementary physical shapes for indexing or registration purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Nozzles (AREA)
  • Package Specialized In Special Use (AREA)

Abstract

"CáPSULAS DE DOSE UNITáRIA E INALADOR DE Pó SECO". O inalador de pó seco (10) compreende uma seção de admissão (20); uma seção de mistura (30) e um bocal (40). O bocal é conectado por uma junta articulada à seção de mistura e pode articular-se de volta para dentro da seção de admissão e ser encoberto por um revestimento (290). A câmara de admissão compreende um êmbolo com uma haste de êmbolo afunilada e mola e um ou mais orifícios para descarga de modo a modular o escoamento do ar através do dispositivo. Ele compreende, opcionalmente, um módulo de retroalimentação para gerar um pulso indicando quando a razão apropriada de escoamento de ar foi obtida. A seção de mistura prende uma cápsula (300) com orifícios contendo um medicamento em pó seco e adicionalmente abre e fecha a cápsula quando a seção de admissão está a um determinado ângulo em relação ao bocal. A seção de mistura é uma câmara Venturi para fornecer um escoamento ciclónico ao ar que passa através da câmara de mistura.
BRPI0012718-3A 1999-07-23 2000-07-21 inalador de pà seco. BR0012718B1 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BRPI0017519A BR0017519B8 (pt) 1999-07-23 2000-07-21 cápsula de medicamento para um inalador, e processo para fabricação de uma cápsula compreendendo um medicamento em pó.

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14546499P 1999-07-23 1999-07-23
US20612300P 2000-05-22 2000-05-22
PCT/US2000/040454 WO2001007107A2 (en) 1999-07-23 2000-07-21 Unit dose capsules and dry powder inhaler

Publications (2)

Publication Number Publication Date
BR0012718A true BR0012718A (pt) 2002-07-16
BR0012718B1 BR0012718B1 (pt) 2010-08-24

Family

ID=26843008

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0012718-3A BR0012718B1 (pt) 1999-07-23 2000-07-21 inalador de pà seco.
BRPI0017519A BR0017519B8 (pt) 1999-07-23 2000-07-21 cápsula de medicamento para um inalador, e processo para fabricação de uma cápsula compreendendo um medicamento em pó.

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0017519A BR0017519B8 (pt) 1999-07-23 2000-07-21 cápsula de medicamento para um inalador, e processo para fabricação de uma cápsula compreendendo um medicamento em pó.

Country Status (16)

Country Link
EP (2) EP1923087B1 (pt)
JP (3) JP2003508184A (pt)
AT (2) ATE390944T1 (pt)
AU (1) AU779693B2 (pt)
BR (2) BR0012718B1 (pt)
CA (2) CA2379137C (pt)
CY (2) CY1105860T1 (pt)
DE (2) DE60030862T2 (pt)
DK (3) DK1649886T3 (pt)
ES (3) ES2275544T3 (pt)
HK (2) HK1116107A1 (pt)
IL (3) IL147724A0 (pt)
MX (1) MX347170B (pt)
NZ (1) NZ516811A (pt)
PT (2) PT1649886E (pt)
WO (1) WO2001007107A2 (pt)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) * 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
WO2002013897A2 (en) 2000-08-14 2002-02-21 Advanced Inhalation Research, Inc. Inhalation device and method
US6595204B2 (en) * 2001-03-01 2003-07-22 Iep Pharmaceutical Devices Inc. Spacer for an inhaler
US6766799B2 (en) 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
US7025056B2 (en) * 2001-05-10 2006-04-11 Vectura Delivery Devices Limited Assymetric inhaler
AU2002353013A1 (en) 2001-12-03 2003-06-17 Massachusetts Institute Of Technology Microscale lyophilization and drying methods for the stabilization of molecules
ES2425392T3 (es) 2002-03-20 2013-10-15 Mannkind Corporation Cartucho para un aparato de inhalación
GB0227128D0 (en) 2002-11-20 2002-12-24 Glaxo Group Ltd A capsule
GB0308969D0 (en) 2003-04-17 2003-05-28 Glaxo Group Ltd Capsules
AU2006225241B2 (en) * 2003-09-24 2008-07-17 Tianda Pharmaceuticals (Australia) Pty Limited Medication Holder
WO2005028006A1 (en) * 2003-09-24 2005-03-31 Medi-Stream Pty Ltd Medication holder
AU2004273547B2 (en) * 2003-09-24 2006-07-06 Tianda Pharmaceuticals (Australia) Pty Ltd Medication holder
US7491194B1 (en) 2004-02-03 2009-02-17 David Oliwa Remote control valve for urine collection bag
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
WO2006010248A1 (en) * 2004-07-26 2006-02-02 1355540 Ontario Inc. Powder inhaler featuring reduced compaction inhaler
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
PL1791542T3 (pl) 2004-08-23 2015-11-30 Mannkind Corp Sole diketopiperazyny do dostarczania leków
US8210171B2 (en) 2004-09-13 2012-07-03 Oriel Therapeutics, Inc. Tubular dry powder drug containment systems, associated inhalers and methods
WO2006066363A1 (en) * 2004-12-23 2006-06-29 Acrux Dds Pty Ltd Dispensing device
US8591457B2 (en) 2005-08-10 2013-11-26 Alza Corporation Method for making a needle-free jet injection drug delivery device
AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
GB2433207B (en) * 2006-02-21 2009-01-07 Jianhe Li Active suction actuated inhalers with timing devices
EP2497484A3 (en) 2006-02-22 2012-11-07 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
CN101437562A (zh) * 2006-03-03 2009-05-20 Stc.Unm公司 具有气动力弹性分散机构的干粉吸入器
EP1844806A1 (de) 2006-04-13 2007-10-17 Boehringer Ingelheim Pharma GmbH Medikamenten-Ausgabevorrichtung, Medikamentenmagazin dafür, und Verfahren zur Entnahme eines Medikaments aus einer Medikamentenkammer
WO2008156586A2 (en) 2007-06-12 2008-12-24 Alkermes, Inc. Inhalation device for powdered substances
EP2020249A1 (de) 2007-08-01 2009-02-04 Boehringer Ingelheim Pharma GmbH & Co. KG Inhalator
ES2546025T3 (es) * 2008-01-24 2015-09-17 Vectura Delivery Devices Limited Inhalador
KR101541209B1 (ko) * 2008-03-27 2015-07-31 맨카인드 코포레이션 건조 분말 흡입 시스템
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
DK2570147T3 (da) * 2008-06-13 2018-01-29 Mannkind Corp Tørpulverinhalator og system til lægemiddelindgivelse
KR101628410B1 (ko) 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
TWI528982B (zh) * 2009-03-04 2016-04-11 曼凱公司 改良的乾粉藥物輸送系統
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US8734845B2 (en) 2009-06-12 2014-05-27 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
WO2011079310A1 (en) * 2009-12-23 2011-06-30 Map Pharmaceuticals,Inc. Enhanced eductor design
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
CN102553038B (zh) * 2010-12-17 2014-07-02 陈庆堂 药粉吸嘴放置盒
MY180552A (en) 2011-04-01 2020-12-02 Mannkind Corp Blister package for pharmaceutical cartridges
GB201107103D0 (en) * 2011-04-27 2011-06-08 Clement Clarke Int Ltd Improvements in drug delivery inhaler devices
US9579473B2 (en) 2011-05-12 2017-02-28 Alfred Von Schuckmann Device for inhaling pulverulent substances
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
US9603907B2 (en) 2012-02-01 2017-03-28 Protalix Ltd. Dry powder formulations of dNase I
US9427534B2 (en) 2012-07-05 2016-08-30 Clement Clarke International Ltd. Drug delivery inhaler devices
CA2878457C (en) 2012-07-12 2021-01-19 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
CA151549S (en) 2013-02-14 2014-06-04 Clement Clarke Int Ltd Spacer for an asthma inhaler
BR112015023168B1 (pt) 2013-03-15 2021-08-10 Mannkind Corporation Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina
CN114848614A (zh) 2013-07-18 2022-08-05 曼金德公司 热稳定性干粉药物组合物和方法
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
DE102014017065B3 (de) * 2014-11-20 2015-11-19 Klaus-Dieter Beller Pulverbehältnis für Pulverinhalatoren
CN107961432A (zh) * 2017-11-16 2018-04-27 惠水县凡趣创意科技有限公司 一种胶囊送药器
BR112020016652A2 (pt) 2018-03-26 2020-12-15 Philip Morris Products S.A. Inalador com cavidade de cápsula de vórtice
EP3911390B1 (en) * 2019-01-14 2022-10-26 Philip Morris Products, S.A. Dry powder inhaler device, dry powder cartridge, and kit

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE794951A (fr) * 1972-02-03 1973-05-29 Parke Davis & Co Conditionnement soluble dans l'eau
DE2502251A1 (de) * 1975-01-17 1976-07-22 Schering Ag Vorrichtung zur inhalation pulverfoermiger feststoffe
US4040536A (en) * 1975-05-05 1977-08-09 R. P. Scherer Corporation Locking hard gelatin capsule
GB2072536B (en) * 1980-03-25 1983-12-07 Malem H Nebuliser
US4487327A (en) * 1982-12-21 1984-12-11 Grayson Robert E Locking capsule
CH661878A5 (de) * 1983-11-04 1987-08-31 Warner Lambert Co Kapsel-dosierungsformen.
DE3639836A1 (de) * 1986-11-21 1988-06-01 Sigrid Bechter Mundstueck fuer ein inhalationsgeraet
DE3727894A1 (de) * 1987-08-21 1989-03-02 Stephan Dieter Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge
US4991605A (en) * 1989-04-24 1991-02-12 Philip Morris Incorporated Container for additive materials for smoking articles
US5170801A (en) * 1990-10-02 1992-12-15 Glaxo Inc. Medical capsule device actuated by radio-frequency (rf) signal
US5797391A (en) * 1991-03-28 1998-08-25 Rhone-Poulenc Rorer Limited Inhaler
US5476093A (en) * 1992-02-14 1995-12-19 Huhtamaki Oy Device for more effective pulverization of a powdered inhalation medicament
GB9216038D0 (en) * 1992-07-28 1992-09-09 Bespak Plc Dispensing apparatus for powdered medicaments
US5896855A (en) * 1992-12-24 1999-04-27 Rhone-Poulenc Rorer Limited Multi dose inhaler apparatus
DK0714314T3 (da) * 1993-08-18 1999-06-23 Fisons Plc Inhalator med åndedrætsregulering
US5524613A (en) * 1993-08-25 1996-06-11 Habley Medical Technology Corporation Controlled multi-pharmaceutical inhaler
PT101450B (pt) * 1994-02-02 1999-11-30 Hovione Produtos Farmaceuticos Novo dispositivo para inalacao
US5641510A (en) * 1994-07-01 1997-06-24 Genentech, Inc. Method for treating capsules used for drug storage
PT805696E (pt) * 1995-01-23 2000-08-31 Direct Haler A S Inalador
DE19519840A1 (de) * 1995-05-31 1996-12-05 Kaewert Klaus Gelantinekapsel
US5758638A (en) * 1995-07-24 1998-06-02 Kreamer; Jeffry W. Indicator for a medicament inhaler
DE19637125A1 (de) * 1996-09-12 1998-03-19 Schuckmann Alfred Von Inhalier-Vorrichtung
GB9626263D0 (en) * 1996-12-18 1997-02-05 Innovata Biomed Ltd Powder inhaler
JP3011898B2 (ja) * 1997-02-20 2000-02-21 フォルテ グロウ メディカル株式会社 吸引器
DE19708406A1 (de) * 1997-03-03 1998-09-10 Alfred Von Schuckmann Gerät zur dosierten Ausgabe von Substanzen
SE9700935D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device

Also Published As

Publication number Publication date
MXPA02000812A (es) 2003-09-25
ES2306002T3 (es) 2008-11-01
JP4608367B2 (ja) 2011-01-12
PT1649886E (pt) 2008-05-28
EP1200149B1 (en) 2006-09-20
IL188519A0 (en) 2008-04-13
CA2379137A1 (en) 2001-02-01
JP5055623B2 (ja) 2012-10-24
PT1200149E (pt) 2007-01-31
JP2005288188A (ja) 2005-10-20
DK1923087T3 (da) 2012-12-03
CA2642084C (en) 2013-02-05
MX347170B (es) 2017-04-18
HK1116107A1 (en) 2008-12-19
AU7138000A (en) 2001-02-13
CY1105860T1 (el) 2011-02-02
ATE390944T1 (de) 2008-04-15
DE60030862D1 (de) 2006-11-02
EP1200149A2 (en) 2002-05-02
IL147724A0 (en) 2002-08-14
BR0017519B8 (pt) 2021-06-22
DK1200149T3 (da) 2007-01-29
CY1110253T1 (el) 2015-01-14
CA2642084A1 (en) 2001-02-01
ES2275544T3 (es) 2007-06-16
IL188519A (en) 2011-07-31
WO2001007107A3 (en) 2001-06-21
BR0017519B1 (pt) 2011-07-12
AU779693B2 (en) 2005-02-03
WO2001007107A9 (en) 2001-07-12
NZ516811A (en) 2002-10-25
EP1923087A2 (en) 2008-05-21
EP1923087A3 (en) 2009-03-25
EP1923087B1 (en) 2012-09-05
DK1649886T3 (da) 2008-05-05
IL147724A (en) 2009-09-22
DE60038511T2 (de) 2009-04-30
JP2008062080A (ja) 2008-03-21
CA2379137C (en) 2007-01-23
DE60038511D1 (de) 2008-05-15
ATE339981T1 (de) 2006-10-15
DE60030862T2 (de) 2007-09-06
HK1090861A1 (en) 2007-01-05
BR0012718B1 (pt) 2010-08-24
ES2395051T3 (es) 2013-02-07
JP2003508184A (ja) 2003-03-04
WO2001007107A2 (en) 2001-02-01

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