MX345861B - Laminina-521 recombinante. - Google Patents
Laminina-521 recombinante.Info
- Publication number
- MX345861B MX345861B MX2013006959A MX2013006959A MX345861B MX 345861 B MX345861 B MX 345861B MX 2013006959 A MX2013006959 A MX 2013006959A MX 2013006959 A MX2013006959 A MX 2013006959A MX 345861 B MX345861 B MX 345861B
- Authority
- MX
- Mexico
- Prior art keywords
- laminin
- stem cells
- single cell
- embryonic stem
- recombinant
- Prior art date
Links
- 210000004027 cell Anatomy 0.000 abstract 4
- 210000001671 embryonic stem cell Anatomy 0.000 abstract 3
- 210000000130 stem cell Anatomy 0.000 abstract 2
- 230000004083 survival effect Effects 0.000 abstract 2
- 102000018233 Fibroblast Growth Factor Human genes 0.000 abstract 1
- 108050007372 Fibroblast Growth Factor Proteins 0.000 abstract 1
- 238000004113 cell culture Methods 0.000 abstract 1
- 239000006285 cell suspension Substances 0.000 abstract 1
- 230000004069 differentiation Effects 0.000 abstract 1
- 238000010494 dissociation reaction Methods 0.000 abstract 1
- 230000005593 dissociations Effects 0.000 abstract 1
- 229940126864 fibroblast growth factor Drugs 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/602—Sox-2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/605—Nanog
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/608—Lin28
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Developmental Biology & Embryology (AREA)
- Gynecology & Obstetrics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Reproductive Health (AREA)
- Medicinal Chemistry (AREA)
- Transplantation (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201061424273P | 2010-12-17 | 2010-12-17 | |
| US201161488353P | 2011-05-20 | 2011-05-20 | |
| US201161533063P | 2011-09-09 | 2011-09-09 | |
| US201161537940P | 2011-09-22 | 2011-09-22 | |
| US201161565380P | 2011-11-30 | 2011-11-30 | |
| US201161565849P | 2011-12-01 | 2011-12-01 | |
| PCT/IB2011/003258 WO2012080842A1 (en) | 2010-12-17 | 2011-12-16 | Recombinant laminin-521 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013006959A MX2013006959A (es) | 2013-12-06 |
| MX345861B true MX345861B (es) | 2017-02-20 |
Family
ID=45755415
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013006959A MX345861B (es) | 2010-12-17 | 2011-12-16 | Laminina-521 recombinante. |
| MX2013006958A MX343462B (es) | 2010-12-17 | 2011-12-16 | Medio del cultivo celular. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013006958A MX343462B (es) | 2010-12-17 | 2011-12-16 | Medio del cultivo celular. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10138292B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2651973B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6002675B2 (cg-RX-API-DMAC7.html) |
| KR (3) | KR101921350B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN103384680B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011342904B2 (cg-RX-API-DMAC7.html) |
| BR (2) | BR112013017632A2 (cg-RX-API-DMAC7.html) |
| CA (2) | CA2826252C (cg-RX-API-DMAC7.html) |
| IL (2) | IL226971B (cg-RX-API-DMAC7.html) |
| MX (2) | MX345861B (cg-RX-API-DMAC7.html) |
| SG (3) | SG191216A1 (cg-RX-API-DMAC7.html) |
| WO (2) | WO2012080844A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2203176B1 (en) | 2007-09-28 | 2014-11-26 | Anthrogenesis Corporation | Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells |
| IL281453B (en) | 2009-11-17 | 2022-07-01 | Astellas Inst For Regenerative Medicine | Methods for preparing human rpe cells and pharmaceutical preparations of human rpe cells |
| MX342995B (es) | 2010-07-13 | 2016-10-21 | Anthrogenesis Corp | Métodos de generar células asesinas naturales. |
| KR101921350B1 (ko) * | 2010-12-17 | 2018-11-22 | 바이오라미나 에이비 | 인간 다능성 줄기세포를 유지하기 위한 시스템 |
| CN104364263B (zh) * | 2011-09-22 | 2018-06-29 | 卡尔·特吕格瓦松 | 含有层粘连蛋白和钙粘蛋白的细胞培养基底 |
| US9828630B2 (en) | 2011-11-30 | 2017-11-28 | Biolamina Ab | Methods of enhancing genetic diagnosis |
| WO2013156855A1 (en) | 2012-04-20 | 2013-10-24 | Biolamina Ab | Maintenance of differentiated cells with laminins |
| US20130330825A1 (en) * | 2012-06-07 | 2013-12-12 | City Of Hope | Attachment substrates for directed differentiation of human embryonic stem cells in culture |
| WO2014037807A2 (en) * | 2012-09-07 | 2014-03-13 | Biolamina Ab | Stem cell bank |
| HUE038620T2 (hu) | 2012-12-03 | 2018-10-29 | Biolamina Ab | Eljárások RPE sejtek elõállítására |
| EP3622960A1 (en) | 2013-02-05 | 2020-03-18 | Celularity, Inc. | Natural killer cells from placenta |
| EP3546568A3 (en) * | 2013-07-02 | 2019-10-23 | National University of Singapore | Differentiation of pluripotent stem cells and cardiac progenitor cells into striated cardiomyocyte fibers using laminins ln-511, ln-521 and ln-221 |
| US12680078B2 (en) | 2013-07-02 | 2026-07-14 | National University Of Singapore | Differentiation of pluripotent stem cells and cardiac progenitor cells into striated cardiomyocyte fibers using laminins LN-511, LN-521 and LN-221 |
| DK3064572T3 (da) * | 2013-11-01 | 2020-05-04 | Bbhc Co Ltd | Fremgangsmåde til fremstilling af inducerede pluripotente stamceller fra mesenchymale stamceller og inducerede pluripotente stamceller produceret ved fremgangsmåden |
| BR112016011096A2 (pt) | 2013-11-27 | 2017-09-19 | Kyoto Prefectural Public Univ Corp | Aplicação de laminina à cultura de célula endotelial da córnea |
| JP6770435B2 (ja) | 2014-10-31 | 2020-10-14 | 京都府公立大学法人 | ラミニンによる網膜および神経の新規治療 |
| MX387839B (es) * | 2014-10-31 | 2025-03-04 | Senju Pharma Co | Laminina para usarse en el tratamiento de una enfermedad, un trastorno o una afección de un endotelio de córnea. |
| SMT201900005T1 (it) * | 2015-02-20 | 2019-05-10 | Inst Nat Sante Rech Med | Uso di una laminina per la differenziazione di cellule pluripotenti in cellule di lignaggio epatocitario |
| WO2017034459A1 (en) * | 2015-08-23 | 2017-03-02 | Diamyd Medical Ab | New use |
| US10683486B2 (en) * | 2015-10-30 | 2020-06-16 | Biolamina Ab | Methods for producing hepatocytes |
| JP6605618B2 (ja) * | 2015-11-10 | 2019-11-20 | 日機装株式会社 | 細胞支持複合体および細胞支持複合体の製造方法 |
| CA3019514A1 (en) | 2016-03-30 | 2017-10-05 | Asterias Biotherapeutics, Inc. | Oligodendrocyte progenitor cell compositions |
| US20190211305A1 (en) * | 2016-08-25 | 2019-07-11 | Kyoto University | Method for Culturing Pluripotent Stem Cells on Specific Laminin |
| WO2018090084A1 (en) * | 2016-11-16 | 2018-05-24 | Cynata Therapeutics Limited | Pluripotent stem cell assay |
| CN106591295B (zh) * | 2016-12-31 | 2019-10-25 | 贵州北科生物科技有限公司 | 一种多功能干细胞培养方法及所用培养基 |
| AU2018262323A1 (en) | 2017-05-05 | 2019-11-21 | National University Of Singapore | Methods for culturing human keratinocytes |
| AU2019342741B2 (en) | 2018-09-19 | 2025-12-11 | Lineage Cell Therapeutics, Inc. | Methods for differentiating pluripotent stem cells in dynamic suspension culture |
| AU2020210757B2 (en) * | 2019-01-23 | 2026-04-16 | Asterias Biotherapeutics, Inc. | Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells |
| CN111621473A (zh) * | 2019-04-03 | 2020-09-04 | 成熙(上海)生物科技有限公司 | 一种新型人源脂肪干细胞制剂的制备方法 |
| CN111617105A (zh) * | 2019-04-03 | 2020-09-04 | 成熙(上海)生物科技有限公司 | 一种脂肪干细胞多细胞活性因子冻干粉的制备方法 |
| WO2021233116A1 (zh) * | 2020-05-21 | 2021-11-25 | 北京大学 | 多能干细胞的成分明确、无异源的培养系统 |
| CN111569048B (zh) * | 2020-05-22 | 2023-04-18 | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | LamG5肽在制备修复睾丸中支持细胞损伤的药物中的应用 |
| WO2025067551A1 (zh) * | 2024-05-16 | 2025-04-03 | 北京百普赛斯生物科技股份有限公司 | 活性增强的改造型Laminin 521蛋白及应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7005252B1 (en) * | 2000-03-09 | 2006-02-28 | Wisconsin Alumni Research Foundation | Serum free cultivation of primate embryonic stem cells |
| PT1572984E (pt) * | 2002-12-16 | 2016-06-03 | Technion Res & Dev Foundation | Sistema de cultura para células estaminais embrionárias humanas sem células alimentadoras e sem xeno |
| BRPI0514778B1 (pt) * | 2004-09-08 | 2018-07-10 | Wisconsin Alumni Research Foundation | Meio para cultivar células tronco embrionárias |
| JP2006087396A (ja) | 2004-09-27 | 2006-04-06 | National Institute For Environmental Studies | 細胞培養基質及びその製造方法 |
| WO2007058401A1 (en) * | 2005-11-18 | 2007-05-24 | Imgen Co., Ltd. | Composition comprising okadaic acid for undifferentiated proliferation of embryonic stem cells |
| EP2420565B1 (en) * | 2006-02-23 | 2017-08-30 | ViaCyte, Inc. | Compositions and methods useful for culturing differentiable cells |
| US10829733B2 (en) | 2007-01-04 | 2020-11-10 | Biolamina Ab | Composition and method for enabling proliferation of pluripotent human stem cells |
| US8951799B2 (en) * | 2007-01-04 | 2015-02-10 | Biolamina Ab | Composition and method for enabling proliferation of pluripotent stem cells |
| CN101605885B (zh) * | 2007-01-04 | 2013-03-27 | 卡尔·特吕格瓦松 | 能够使多能干细胞增殖的组合物及方法 |
| EP2559756B1 (en) | 2007-07-01 | 2019-12-18 | Janssen Biotech, Inc. | Single pluripotent stem cell culture |
| JP5951254B2 (ja) * | 2008-03-17 | 2016-07-13 | ザ スクリプス リサーチ インスティテュート | 人工多能性幹細胞を作製するための化学的手法と遺伝的手法の組み合わせ法 |
| CN102131919B (zh) * | 2008-03-31 | 2017-05-03 | 东方酵母工业株式会社 | 一种增殖多能性干细胞的方法 |
| WO2010005995A1 (en) | 2008-07-07 | 2010-01-14 | Mass Institute Of Technology | Micropatterned co-culture systems as infectious disease analysis platforms |
| WO2010137746A1 (en) | 2009-05-29 | 2010-12-02 | Kyoto University | Method for producing induced pluripotent stem cells and method for culturing the same |
| JP5700301B2 (ja) * | 2009-06-03 | 2015-04-15 | 国立大学法人大阪大学 | 多能性幹細胞からの神経堤細胞群の分化誘導方法 |
| CA2707296A1 (en) | 2009-06-12 | 2010-12-12 | Richard T. Scott, Jr. | Method for relative quantitation of chromosomal dna copy number in a single or few cells |
| KR101921350B1 (ko) | 2010-12-17 | 2018-11-22 | 바이오라미나 에이비 | 인간 다능성 줄기세포를 유지하기 위한 시스템 |
-
2011
- 2011-12-16 KR KR1020137018840A patent/KR101921350B1/ko active Active
- 2011-12-16 MX MX2013006959A patent/MX345861B/es active IP Right Grant
- 2011-12-16 SG SG2013046727A patent/SG191216A1/en unknown
- 2011-12-16 CN CN201180067656.XA patent/CN103384680B/zh active Active
- 2011-12-16 AU AU2011342904A patent/AU2011342904B2/en active Active
- 2011-12-16 JP JP2013543905A patent/JP6002675B2/ja active Active
- 2011-12-16 MX MX2013006958A patent/MX343462B/es active IP Right Grant
- 2011-12-16 US US13/328,156 patent/US10138292B2/en active Active
- 2011-12-16 CN CN201180067474.2A patent/CN103384679B/zh active Active
- 2011-12-16 CA CA2826252A patent/CA2826252C/en active Active
- 2011-12-16 SG SG10201510405PA patent/SG10201510405PA/en unknown
- 2011-12-16 US US13/328,145 patent/US8415156B2/en active Active
- 2011-12-16 BR BR112013017632A patent/BR112013017632A2/pt not_active Application Discontinuation
- 2011-12-16 EP EP11820800.8A patent/EP2651973B1/en active Active
- 2011-12-16 SG SG2013046701A patent/SG191215A1/en unknown
- 2011-12-16 WO PCT/IB2011/003265 patent/WO2012080844A1/en not_active Ceased
- 2011-12-16 CA CA2828794A patent/CA2828794C/en active Active
- 2011-12-16 KR KR1020197003578A patent/KR101966033B1/ko active Active
- 2011-12-16 BR BR112013017629A patent/BR112013017629A2/pt not_active Application Discontinuation
- 2011-12-16 WO PCT/IB2011/003258 patent/WO2012080842A1/en not_active Ceased
- 2011-12-16 KR KR1020137018841A patent/KR20140012047A/ko not_active Abandoned
- 2011-12-16 JP JP2013543904A patent/JP5990531B2/ja active Active
- 2011-12-16 EP EP11820801.6A patent/EP2651974B1/en active Active
-
2013
- 2013-06-16 IL IL226971A patent/IL226971B/en active IP Right Grant
-
2019
- 2019-10-26 IL IL270186A patent/IL270186B/en active IP Right Grant
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