MX345724B - Composiciones y métodos para aplicación tópica y suministro transdérmico de toxinas botulínicas. - Google Patents

Composiciones y métodos para aplicación tópica y suministro transdérmico de toxinas botulínicas.

Info

Publication number
MX345724B
MX345724B MX2011011878A MX2011011878A MX345724B MX 345724 B MX345724 B MX 345724B MX 2011011878 A MX2011011878 A MX 2011011878A MX 2011011878 A MX2011011878 A MX 2011011878A MX 345724 B MX345724 B MX 345724B
Authority
MX
Mexico
Prior art keywords
botulinum toxin
methods
topical application
compositions
transdermal delivery
Prior art date
Application number
MX2011011878A
Other languages
English (en)
Inventor
M Waugh Jacob
D Dake Michael
Original Assignee
Revance Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Revance Therapeutics Inc filed Critical Revance Therapeutics Inc
Publication of MX345724B publication Critical patent/MX345724B/es

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61Q19/08—Anti-ageing preparations
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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Abstract

La presente invención se refiere a una composición para aplicación tópica de una toxina botulínica (que incluye derivados de toxina botulínica) que comprende una toxina botulínica y un vehículo que comprende un esqueleto polimérico que comprende un polipéptido de cadena larga o un polímero sin peptidilo que tiene adheridos grupos de ramificación o de "eficiencia" cargados en forma positiva. La presente invención también se refiere a métodos para reducir parálisis muscular y otras condiciones que pueden ser tratadas con una toxina botulínica, particularmente parálisis de músculos subcutáneos, y más particularmente músculos faciales, aplicando en forma tópica una cantidad efectiva de la toxina botulínica y un vehículo, en conjunto, a la piel o epitelio del sujeto. También se describen equipos para la administración.
MX2011011878A 2004-03-03 2005-03-03 Composiciones y métodos para aplicación tópica y suministro transdérmico de toxinas botulínicas. MX345724B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55001504P 2004-03-03 2004-03-03
PCT/US2005/007524 WO2005084410A2 (en) 2004-03-03 2005-03-03 Compositions and methods for topical application and transdermal delivery of botulinum toxins

Publications (1)

Publication Number Publication Date
MX345724B true MX345724B (es) 2017-02-13

Family

ID=34919562

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2011011878A MX345724B (es) 2004-03-03 2005-03-03 Composiciones y métodos para aplicación tópica y suministro transdérmico de toxinas botulínicas.
MXPA06009898A MXPA06009898A (es) 2004-03-03 2005-03-03 Composiciones y metodos para la aplicacion topica y suministro transdermico de toxinas botulinicas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MXPA06009898A MXPA06009898A (es) 2004-03-03 2005-03-03 Composiciones y metodos para la aplicacion topica y suministro transdermico de toxinas botulinicas.

Country Status (25)

Country Link
US (2) US8404249B2 (es)
EP (3) EP1729821B1 (es)
JP (1) JP5095388B2 (es)
KR (3) KR101330775B1 (es)
CN (2) CN1946431B (es)
AU (1) AU2005218665A1 (es)
BR (1) BRPI0508410B8 (es)
CA (1) CA2558408C (es)
CR (1) CR8602A (es)
CY (1) CY1120816T1 (es)
DK (3) DK2656859T3 (es)
ES (3) ES2554821T3 (es)
HK (4) HK1105774A1 (es)
HU (1) HUE025656T2 (es)
IL (4) IL177816A (es)
LT (1) LT2985039T (es)
MX (2) MX345724B (es)
NO (1) NO20064490L (es)
NZ (1) NZ592041A (es)
PL (1) PL2985039T3 (es)
PT (3) PT1729821E (es)
SG (3) SG10201400339VA (es)
SI (3) SI1729821T1 (es)
TR (1) TR201815364T4 (es)
WO (1) WO2005084410A2 (es)

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IL237388A0 (en) 2015-04-30
JP5095388B2 (ja) 2012-12-12
EP2656859A2 (en) 2013-10-30
CN1946431A (zh) 2007-04-11
DK2656859T3 (en) 2016-01-11
HK1162952A1 (zh) 2012-09-07
IL237388A (en) 2017-07-31
CA2558408A1 (en) 2005-09-15
CN102357062B (zh) 2015-08-05
CN1946431B (zh) 2011-12-07
NO20064490L (no) 2006-10-03
KR20130060360A (ko) 2013-06-07
SG10201803560WA (en) 2018-06-28
ES2431610T3 (es) 2013-11-27
HK1105774A1 (en) 2008-02-22
EP2656859B1 (en) 2015-10-21
ES2691498T3 (es) 2018-11-27
EP2985039B1 (en) 2018-08-01
IL177816A0 (en) 2006-12-31
WO2005084410A3 (en) 2006-06-29
US20050196414A1 (en) 2005-09-08
IL237386A (en) 2017-07-31
US20080107690A1 (en) 2008-05-08
US8398997B2 (en) 2013-03-19
EP2985039A1 (en) 2016-02-17

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