MX345724B - Composiciones y métodos para aplicación tópica y suministro transdérmico de toxinas botulínicas. - Google Patents

Composiciones y métodos para aplicación tópica y suministro transdérmico de toxinas botulínicas.

Info

Publication number
MX345724B
MX345724B MX2011011878A MX2011011878A MX345724B MX 345724 B MX345724 B MX 345724B MX 2011011878 A MX2011011878 A MX 2011011878A MX 2011011878 A MX2011011878 A MX 2011011878A MX 345724 B MX345724 B MX 345724B
Authority
MX
Mexico
Prior art keywords
botulinum toxin
methods
topical application
compositions
transdermal delivery
Prior art date
Application number
MX2011011878A
Other languages
English (en)
Inventor
M Waugh Jacob
D Dake Michael
Original Assignee
Revance Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Revance Therapeutics Inc filed Critical Revance Therapeutics Inc
Publication of MX345724B publication Critical patent/MX345724B/es

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
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    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
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  • Neurology (AREA)
  • Biomedical Technology (AREA)
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  • Endocrinology (AREA)
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  • Birds (AREA)
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  • Hematology (AREA)
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  • Rheumatology (AREA)
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  • Child & Adolescent Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pregnancy & Childbirth (AREA)

Abstract

La presente invención se refiere a una composición para aplicación tópica de una toxina botulínica (que incluye derivados de toxina botulínica) que comprende una toxina botulínica y un vehículo que comprende un esqueleto polimérico que comprende un polipéptido de cadena larga o un polímero sin peptidilo que tiene adheridos grupos de ramificación o de "eficiencia" cargados en forma positiva. La presente invención también se refiere a métodos para reducir parálisis muscular y otras condiciones que pueden ser tratadas con una toxina botulínica, particularmente parálisis de músculos subcutáneos, y más particularmente músculos faciales, aplicando en forma tópica una cantidad efectiva de la toxina botulínica y un vehículo, en conjunto, a la piel o epitelio del sujeto. También se describen equipos para la administración.
MX2011011878A 2004-03-03 2005-03-03 Composiciones y métodos para aplicación tópica y suministro transdérmico de toxinas botulínicas. MX345724B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55001504P 2004-03-03 2004-03-03
PCT/US2005/007524 WO2005084410A2 (en) 2004-03-03 2005-03-03 Compositions and methods for topical application and transdermal delivery of botulinum toxins

Publications (1)

Publication Number Publication Date
MX345724B true MX345724B (es) 2017-02-13

Family

ID=34919562

Family Applications (2)

Application Number Title Priority Date Filing Date
MXPA06009898A MXPA06009898A (es) 2004-03-03 2005-03-03 Composiciones y metodos para la aplicacion topica y suministro transdermico de toxinas botulinicas.
MX2011011878A MX345724B (es) 2004-03-03 2005-03-03 Composiciones y métodos para aplicación tópica y suministro transdérmico de toxinas botulínicas.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MXPA06009898A MXPA06009898A (es) 2004-03-03 2005-03-03 Composiciones y metodos para la aplicacion topica y suministro transdermico de toxinas botulinicas.

Country Status (25)

Country Link
US (2) US8404249B2 (es)
EP (3) EP1729821B1 (es)
JP (1) JP5095388B2 (es)
KR (3) KR101330775B1 (es)
CN (2) CN102357062B (es)
AU (1) AU2005218665A1 (es)
BR (1) BRPI0508410B8 (es)
CA (1) CA2558408C (es)
CR (1) CR8602A (es)
CY (1) CY1120816T1 (es)
DK (3) DK1729821T3 (es)
ES (3) ES2691498T3 (es)
HK (4) HK1105774A1 (es)
HU (1) HUE025656T2 (es)
IL (4) IL177816A (es)
LT (1) LT2985039T (es)
MX (2) MXPA06009898A (es)
NO (1) NO20064490L (es)
NZ (1) NZ592041A (es)
PL (1) PL2985039T3 (es)
PT (3) PT2985039T (es)
SG (3) SG10201803560WA (es)
SI (3) SI1729821T1 (es)
TR (1) TR201815364T4 (es)
WO (1) WO2005084410A2 (es)

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