MX338879B - Proceso de esterilizacion por filtracion en estado diluido para biopolimeros viscoelasticos. - Google Patents

Proceso de esterilizacion por filtracion en estado diluido para biopolimeros viscoelasticos.

Info

Publication number
MX338879B
MX338879B MX2010005276A MX2010005276A MX338879B MX 338879 B MX338879 B MX 338879B MX 2010005276 A MX2010005276 A MX 2010005276A MX 2010005276 A MX2010005276 A MX 2010005276A MX 338879 B MX338879 B MX 338879B
Authority
MX
Mexico
Prior art keywords
biopolymers
viscoelastic
dilute
sterilization process
biopolymer
Prior art date
Application number
MX2010005276A
Other languages
English (en)
Other versions
MX2010005276A (es
Inventor
Menakem Fuchs
Dror Eyal
Yehuda Zelig
Original Assignee
Bio Technology General Israel Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Technology General Israel Ltd filed Critical Bio Technology General Israel Ltd
Publication of MX2010005276A publication Critical patent/MX2010005276A/es
Publication of MX338879B publication Critical patent/MX338879B/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere a los productos manufacturados de ácido hialurónico se utilizan en numerosas aplicaciones quirúrgicas que incluyen la complementación viscoelástica para el tratamiento de la osteoartritis, sin embargo, las técnicas de esterilización tradicionales dan por resultado la descomposición de estos biopolímeros viscoelásticos de alto peso molecular y de esta manera son inadecuadas. Se dan a conocer procesos para obtener soluciones estériles, concentradas de biopolímeros de alto peso molecular tal como el ácido hialurónico. Los procesos incluyen la esterilización por filtración con una preparación diluida del biopolímero y la concentración del biopolímero esterilizado por filtración, diluido mediante la ultrafiltración hasta una concentración deseada.
MX2010005276A 2007-11-13 2008-11-12 Proceso de esterilizacion por filtracion en estado diluido para biopolimeros viscoelasticos. MX338879B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07120568 2007-11-13
PCT/IB2008/003042 WO2009063291A1 (en) 2007-11-13 2008-11-12 Dilute filtration sterilization process for viscoelastic biopolymers

Publications (2)

Publication Number Publication Date
MX2010005276A MX2010005276A (es) 2010-08-31
MX338879B true MX338879B (es) 2016-05-04

Family

ID=39060256

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010005276A MX338879B (es) 2007-11-13 2008-11-12 Proceso de esterilizacion por filtracion en estado diluido para biopolimeros viscoelasticos.

Country Status (14)

Country Link
US (3) US20110130473A1 (es)
EP (1) EP2209814B1 (es)
JP (1) JP2011503047A (es)
KR (1) KR20100094982A (es)
CN (1) CN101855248B (es)
AU (1) AU2008322629B2 (es)
CA (1) CA2705850C (es)
ES (1) ES2622834T3 (es)
IL (1) IL205402A (es)
MX (1) MX338879B (es)
NZ (1) NZ584919A (es)
PL (1) PL2209814T3 (es)
RU (1) RU2501811C2 (es)
WO (1) WO2009063291A1 (es)

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EP2209814B1 (en) 2007-11-13 2017-01-25 Bio-Technology General (Israel) Ltd. Dilute filtration sterilization process for viscoelastic biopolymers
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JP2011195607A (ja) * 2010-03-17 2011-10-06 Denki Kagaku Kogyo Kk ヒアルロン酸及び／又はその塩の精製法
JP2011195608A (ja) * 2010-03-17 2011-10-06 Denki Kagaku Kogyo Kk ヒアルロン酸及び／又はその塩の精製法
JP2011195611A (ja) * 2010-03-17 2011-10-06 Denki Kagaku Kogyo Kk ヒアルロン酸及び／又はその塩の精製法
CN102492051B (zh) * 2011-12-13 2013-08-28 中南大学 玉竹的深加工及综合利用工艺
TWI424007B (zh) 2011-12-22 2014-01-21 Ind Tech Res Inst 使膠體交聯的方法與藉由此方法形成之經交聯的膠體
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CN102978257B (zh) * 2012-12-20 2014-12-10 江苏久吾高科技股份有限公司 一种右旋糖酐的生产方法
US10519419B2 (en) * 2014-01-23 2019-12-31 Nissan Chemical Corporation Method for producing culture medium composition
CN104193850A (zh) * 2014-08-16 2014-12-10 厦门世达膜科技有限公司 一种肝素钠粗品的生产方法
CN104804105B (zh) * 2015-04-08 2018-04-27 成都郫县新星成明食品研究所 采用陶瓷膜过滤法制备卡拉胶的方法
MY195591A (en) 2017-01-11 2023-02-02 Ferring Bv A Fast Disintegrating Pharmaceutical Composition
CN110545824A (zh) 2017-03-07 2019-12-06 持田制药株式会社 海藻酸液体制剂
WO2020016820A1 (en) 2018-07-18 2020-01-23 Bio-Technology General (Israel) Ltd. Process of, and arrangement for, sterile filtering a non-newtonian liquid and formulation of a liquid obtainable thereby
CN110760015B (zh) * 2019-11-19 2022-07-22 河北鑫合生物化工有限公司 改进的三赞胶的提取方法
JPWO2023219171A1 (es) * 2022-05-13 2023-11-16

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Also Published As

Publication number Publication date
MX2010005276A (es) 2010-08-31
RU2010118163A (ru) 2011-12-20
RU2501811C2 (ru) 2013-12-20
ES2622834T3 (es) 2017-07-07
AU2008322629B2 (en) 2013-05-16
NZ584919A (en) 2012-05-25
EP2209814A1 (en) 2010-07-28
KR20100094982A (ko) 2010-08-27
AU2008322629A1 (en) 2009-05-22
JP2011503047A (ja) 2011-01-27
WO2009063291A8 (en) 2009-09-17
PL2209814T3 (pl) 2017-08-31
IL205402A (en) 2015-10-29
IL205402A0 (en) 2010-12-30
CA2705850A1 (en) 2009-05-22
CN101855248B (zh) 2012-08-22
CN101855248A (zh) 2010-10-06
WO2009063291A1 (en) 2009-05-22
CA2705850C (en) 2016-07-19
US9896518B2 (en) 2018-02-20
EP2209814B1 (en) 2017-01-25
US20110130473A1 (en) 2011-06-02
US20180142041A1 (en) 2018-05-24
US20140018315A1 (en) 2014-01-16

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