MX336489B - Hormona foliculo estimulante humana recombinante composicion farmaceutica que la comprende y uso de la misma. - Google Patents
Hormona foliculo estimulante humana recombinante composicion farmaceutica que la comprende y uso de la misma.Info
- Publication number
- MX336489B MX336489B MX2013000500A MX2013000500A MX336489B MX 336489 B MX336489 B MX 336489B MX 2013000500 A MX2013000500 A MX 2013000500A MX 2013000500 A MX2013000500 A MX 2013000500A MX 336489 B MX336489 B MX 336489B
- Authority
- MX
- Mexico
- Prior art keywords
- recombinant human
- stimulating hormone
- fsh
- human follicle
- improved recombinant
- Prior art date
Links
- 102000003864 Human Follicle Stimulating Hormone Human genes 0.000 title 1
- 108010082302 Human Follicle Stimulating Hormone Proteins 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 2
- 230000011496 cAMP-mediated signaling Effects 0.000 abstract 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 abstract 1
- 239000003163 gonadal steroid hormone Substances 0.000 abstract 1
- 208000000509 infertility Diseases 0.000 abstract 1
- 230000036512 infertility Effects 0.000 abstract 1
- 231100000535 infertility Toxicity 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 230000002485 urinary effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pregnancy & Childbirth (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invención se refiere a preparaciones que comprenden una FSH mejorada que puede estimular la liberación de esteroides sexuales en una concentración mucho menor que la FSH de uso habitual, que es una FSH urinaria o una FSH recombinante que se obtiene de células CHO, y que actúa de manera independiente de la señalización del AMPc. Estas preparaciones que comprenden una FSH mejorada pueden usarse en el tratamiento de la infertilidad.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2010/004769 WO2012016576A1 (en) | 2010-08-04 | 2010-08-04 | Improved recombinant human follicle-stimulating hormone |
PCT/EP2011/063492 WO2012017058A1 (en) | 2010-08-04 | 2011-08-04 | Improved recombinant human follicle-stimulating hormone |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013000500A MX2013000500A (es) | 2013-02-21 |
MX336489B true MX336489B (es) | 2016-01-21 |
Family
ID=43242604
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013000500A MX336489B (es) | 2010-08-04 | 2011-08-04 | Hormona foliculo estimulante humana recombinante composicion farmaceutica que la comprende y uso de la misma. |
Country Status (27)
Country | Link |
---|---|
US (1) | US9527899B2 (es) |
EP (2) | EP3075744B1 (es) |
JP (2) | JP6001534B2 (es) |
KR (1) | KR20130136448A (es) |
CN (2) | CN106146646A (es) |
AR (1) | AR082852A1 (es) |
AU (1) | AU2011287525B2 (es) |
BR (1) | BR112013004051A2 (es) |
CA (1) | CA2805134C (es) |
CU (1) | CU24043B1 (es) |
CY (1) | CY1117778T1 (es) |
DK (1) | DK2601210T3 (es) |
EA (1) | EA029955B1 (es) |
ES (2) | ES2764083T3 (es) |
HR (1) | HRP20160671T1 (es) |
HU (1) | HUE028357T2 (es) |
IL (1) | IL223867B (es) |
MX (1) | MX336489B (es) |
NZ (1) | NZ604877A (es) |
PL (1) | PL2601210T3 (es) |
PT (1) | PT2601210T (es) |
RS (1) | RS54905B1 (es) |
SG (1) | SG186755A1 (es) |
SI (1) | SI2601210T1 (es) |
SM (1) | SMT201600219B (es) |
WO (2) | WO2012016576A1 (es) |
ZA (1) | ZA201209436B (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI488640B (zh) * | 2008-04-16 | 2015-06-21 | Ferring Int Ct Sa | 藥學製劑 |
WO2012016576A1 (en) | 2010-08-04 | 2012-02-09 | Glycotope Gmbh | Improved recombinant human follicle-stimulating hormone |
WO2012168680A1 (en) | 2011-06-06 | 2012-12-13 | Ferring B.V. | Pharmaceutical preparation comprising recombinant fsh |
JO3092B1 (ar) | 2011-08-08 | 2017-03-15 | Ferring Bv | مركب لتحفيز مسيطر عليه للمبيض |
EP3533874A1 (en) * | 2012-07-30 | 2019-09-04 | Trophogen Inc. | Glycoprotein hormone long-acting superagonists |
CN104543416B (zh) * | 2013-10-09 | 2018-06-19 | 中国科学院大连化学物理研究所 | 一种调节雌性动物繁殖性能的功能性单糖饲料及其应用 |
CN103740754B (zh) * | 2013-10-25 | 2015-06-24 | 中国食品药品检定研究院 | 含有鼠神经生长因子的表达载体及细胞 |
KR20160144480A (ko) * | 2014-04-18 | 2016-12-16 | 글리코토페 게엠베하 | 개선된 재조합 인간 난포-자극 호르몬을 이용한 조절된 난소 과다자극 |
EP3091033A1 (en) * | 2015-05-06 | 2016-11-09 | Gamamabs Pharma | Anti-human-her3 antibodies and uses thereof |
WO2017025566A1 (en) * | 2015-08-10 | 2017-02-16 | Glycotope Gmbh | Improved recombinant factor vii |
BR112018003455A2 (pt) | 2015-09-17 | 2018-09-25 | Glycotope Gmbh | composição ou composição farmacêutica e uso da composição |
CN106053861A (zh) * | 2016-07-28 | 2016-10-26 | 高常青 | 一种卵泡刺激素生物活性强度检测方法 |
EP4055038A4 (en) * | 2019-11-06 | 2023-11-15 | The Regents of the University of Colorado, a body corporate | MODIFIED FOLLICLE-STIMULATING HORMONE AND METHOD OF USE THEREOF |
CN116375862A (zh) * | 2021-09-07 | 2023-07-04 | 苏州晟济药业有限公司 | 一种单域抗体或其抗原结合片段及其应用 |
WO2023215914A1 (en) * | 2022-05-06 | 2023-11-09 | The Regents Of The University Of Colorado, A Body Corporate | Modified follicle-stimulating hormone and methods of using the same |
WO2024100548A1 (en) * | 2022-11-08 | 2024-05-16 | Oncogreen Therapeutics S.A. | Compound with anti-metastatic effect |
WO2024100549A1 (en) * | 2022-11-08 | 2024-05-16 | Oncogreen Therapeutics S.A. | Compounds for use in macrophage reprogramming |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1176976E (pt) | 1999-05-07 | 2006-11-30 | Applied Research Systems | Utilização de lh administrada na fase folicular média e tardia para o tratamento de mulheres anovulatórias. |
CA2464368A1 (en) * | 2001-10-22 | 2003-05-01 | Applied Research Systems Ars Holding N.V. | Compositions of fsh with high sialylation degree and their use for the preparation of medicaments |
CA2557725C (en) * | 2004-02-13 | 2015-06-30 | Glycotope Gmbh | Highly active glycoproteins-process conditions and an efficient method for their production |
PT2073842E (pt) * | 2006-09-10 | 2015-04-07 | Glycotope Gmbh | Utilização de células humanas provenientes de uma leucemia mielóide para expressão de anticorpos |
TWI488640B (zh) * | 2008-04-16 | 2015-06-21 | Ferring Int Ct Sa | 藥學製劑 |
GB2459641B (en) * | 2008-04-16 | 2012-06-27 | Ubiquisys Ltd | Basestation power control |
EP2325194A1 (en) | 2009-11-24 | 2011-05-25 | Glycotope GmbH | Process for the purification of glycoproteins |
WO2012016576A1 (en) * | 2010-08-04 | 2012-02-09 | Glycotope Gmbh | Improved recombinant human follicle-stimulating hormone |
-
2010
- 2010-08-04 WO PCT/EP2010/004769 patent/WO2012016576A1/en active Application Filing
-
2011
- 2011-08-04 CA CA2805134A patent/CA2805134C/en not_active Expired - Fee Related
- 2011-08-04 CN CN201610363950.XA patent/CN106146646A/zh active Pending
- 2011-08-04 EA EA201390194A patent/EA029955B1/ru not_active IP Right Cessation
- 2011-08-04 AR ARP110102828A patent/AR082852A1/es unknown
- 2011-08-04 US US13/814,059 patent/US9527899B2/en active Active
- 2011-08-04 CN CN201180037096.3A patent/CN103068839B/zh active Active
- 2011-08-04 JP JP2013522259A patent/JP6001534B2/ja not_active Expired - Fee Related
- 2011-08-04 EP EP16168841.1A patent/EP3075744B1/en not_active Revoked
- 2011-08-04 KR KR1020137005553A patent/KR20130136448A/ko not_active Application Discontinuation
- 2011-08-04 HU HUE11757190A patent/HUE028357T2/en unknown
- 2011-08-04 BR BR112013004051A patent/BR112013004051A2/pt not_active Application Discontinuation
- 2011-08-04 ES ES16168841T patent/ES2764083T3/es active Active
- 2011-08-04 DK DK11757190.1T patent/DK2601210T3/en active
- 2011-08-04 PL PL11757190.1T patent/PL2601210T3/pl unknown
- 2011-08-04 AU AU2011287525A patent/AU2011287525B2/en not_active Ceased
- 2011-08-04 WO PCT/EP2011/063492 patent/WO2012017058A1/en active Application Filing
- 2011-08-04 EP EP11757190.1A patent/EP2601210B1/en not_active Revoked
- 2011-08-04 RS RS20160459A patent/RS54905B1/sr unknown
- 2011-08-04 SI SI201130854A patent/SI2601210T1/sl unknown
- 2011-08-04 NZ NZ604877A patent/NZ604877A/en not_active IP Right Cessation
- 2011-08-04 SG SG2012093191A patent/SG186755A1/en unknown
- 2011-08-04 MX MX2013000500A patent/MX336489B/es unknown
- 2011-08-04 ES ES11757190.1T patent/ES2576868T3/es active Active
- 2011-08-04 PT PT117571901T patent/PT2601210T/pt unknown
-
2012
- 2012-12-12 ZA ZA2012/09436A patent/ZA201209436B/en unknown
- 2012-12-25 IL IL223867A patent/IL223867B/en active IP Right Grant
-
2013
- 2013-02-04 CU CU2013000019A patent/CU24043B1/es active IP Right Grant
-
2016
- 2016-06-13 HR HRP20160671TT patent/HRP20160671T1/hr unknown
- 2016-06-16 CY CY20161100539T patent/CY1117778T1/el unknown
- 2016-06-24 JP JP2016125181A patent/JP2016168055A/ja not_active Withdrawn
- 2016-07-06 SM SM201600219T patent/SMT201600219B/it unknown
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