CU24043B1 - Hormona foliculoestimulante humana recombinante, composición farmacéutica que la comprende - Google Patents
Hormona foliculoestimulante humana recombinante, composición farmacéutica que la comprendeInfo
- Publication number
- CU24043B1 CU24043B1 CU2013000019A CU20130019A CU24043B1 CU 24043 B1 CU24043 B1 CU 24043B1 CU 2013000019 A CU2013000019 A CU 2013000019A CU 20130019 A CU20130019 A CU 20130019A CU 24043 B1 CU24043 B1 CU 24043B1
- Authority
- CU
- Cuba
- Prior art keywords
- fsh
- foliculating
- understands
- hormone
- pharmaceutical composition
- Prior art date
Links
- 229940088597 hormone Drugs 0.000 title 1
- 239000005556 hormone Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 2
- 230000011496 cAMP-mediated signaling Effects 0.000 abstract 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 abstract 1
- 208000000509 infertility Diseases 0.000 abstract 1
- 230000036512 infertility Effects 0.000 abstract 1
- 231100000535 infertility Toxicity 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- 230000002485 urinary effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pregnancy & Childbirth (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Preparaciones que comprenden una FSH mejorada que puede estimular la liberación de esteroides sexuales en una concentración mucho menor que la FSH de uso habitual, que es una FSH urinaria o una FSH recombinante que se obtiene de células CHO, y que actúa de manera independiente de la señalización del AMPc. Estas preparaciones que comprenden una FSH mejorada pueden usarse en el tratamiento de la infertilidad.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2010/004769 WO2012016576A1 (en) | 2010-08-04 | 2010-08-04 | Improved recombinant human follicle-stimulating hormone |
PCT/EP2011/063492 WO2012017058A1 (en) | 2010-08-04 | 2011-08-04 | Improved recombinant human follicle-stimulating hormone |
Publications (2)
Publication Number | Publication Date |
---|---|
CU20130019A7 CU20130019A7 (es) | 2013-05-31 |
CU24043B1 true CU24043B1 (es) | 2014-11-27 |
Family
ID=43242604
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CU2013000019A CU24043B1 (es) | 2010-08-04 | 2013-02-04 | Hormona foliculoestimulante humana recombinante, composición farmacéutica que la comprende |
Country Status (27)
Country | Link |
---|---|
US (1) | US9527899B2 (es) |
EP (2) | EP2601210B1 (es) |
JP (2) | JP6001534B2 (es) |
KR (1) | KR20130136448A (es) |
CN (2) | CN106146646A (es) |
AR (1) | AR082852A1 (es) |
AU (1) | AU2011287525B2 (es) |
BR (1) | BR112013004051A2 (es) |
CA (1) | CA2805134C (es) |
CU (1) | CU24043B1 (es) |
CY (1) | CY1117778T1 (es) |
DK (1) | DK2601210T3 (es) |
EA (1) | EA029955B1 (es) |
ES (2) | ES2576868T3 (es) |
HR (1) | HRP20160671T1 (es) |
HU (1) | HUE028357T2 (es) |
IL (1) | IL223867B (es) |
MX (1) | MX336489B (es) |
NZ (1) | NZ604877A (es) |
PL (1) | PL2601210T3 (es) |
PT (1) | PT2601210T (es) |
RS (1) | RS54905B1 (es) |
SG (1) | SG186755A1 (es) |
SI (1) | SI2601210T1 (es) |
SM (1) | SMT201600219B (es) |
WO (2) | WO2012016576A1 (es) |
ZA (1) | ZA201209436B (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI488640B (zh) * | 2008-04-16 | 2015-06-21 | Ferring Int Ct Sa | 藥學製劑 |
WO2012016576A1 (en) | 2010-08-04 | 2012-02-09 | Glycotope Gmbh | Improved recombinant human follicle-stimulating hormone |
EP2717904A1 (en) | 2011-06-06 | 2014-04-16 | Ferring BV | Pharmaceutical preparation comprising recombinant fsh |
JO3092B1 (ar) | 2011-08-08 | 2017-03-15 | Ferring Bv | مركب لتحفيز مسيطر عليه للمبيض |
RS58881B1 (sr) * | 2012-07-30 | 2019-08-30 | Trophogen Inc | Dugodelujući superagonisti glikoproteinskih hormona |
CN104543416B (zh) * | 2013-10-09 | 2018-06-19 | 中国科学院大连化学物理研究所 | 一种调节雌性动物繁殖性能的功能性单糖饲料及其应用 |
CN103740754B (zh) * | 2013-10-25 | 2015-06-24 | 中国食品药品检定研究院 | 含有鼠神经生长因子的表达载体及细胞 |
BR112016023668A2 (pt) | 2014-04-18 | 2017-10-17 | Glycotope Gmbh | hiperestimulação ovariana controlada com hormônio de estimulação de folículo humano recombinante aperfeiçoado |
EP3091033A1 (en) * | 2015-05-06 | 2016-11-09 | Gamamabs Pharma | Anti-human-her3 antibodies and uses thereof |
WO2017025566A1 (en) * | 2015-08-10 | 2017-02-16 | Glycotope Gmbh | Improved recombinant factor vii |
EA201890163A1 (ru) * | 2015-09-17 | 2018-10-31 | Гликотоп Гмбх | Композиция фолликулостимулирующего гормона млекопитающего с повышенной стабильностью |
CN106053861A (zh) * | 2016-07-28 | 2016-10-26 | 高常青 | 一种卵泡刺激素生物活性强度检测方法 |
EP4055038A4 (en) * | 2019-11-06 | 2023-11-15 | The Regents of the University of Colorado, a body corporate | MODIFIED FOLLICLE-STIMULATING HORMONE AND METHOD OF USE THEREOF |
CN115433276B (zh) * | 2021-09-07 | 2024-04-02 | 苏州晟济药业有限公司 | 一种vhh抗体或其抗原片段的突变体及其应用 |
WO2023215914A1 (en) * | 2022-05-06 | 2023-11-09 | The Regents Of The University Of Colorado, A Body Corporate | Modified follicle-stimulating hormone and methods of using the same |
WO2024100548A1 (en) * | 2022-11-08 | 2024-05-16 | Oncogreen Therapeutics S.A. | Compound with anti-metastatic effect |
WO2024100549A1 (en) * | 2022-11-08 | 2024-05-16 | Oncogreen Therapeutics S.A. | Compounds for use in macrophage reprogramming |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE332705T1 (de) | 1999-05-07 | 2006-08-15 | Applied Research Systems | Verwendung von in der mittlere oder späte follikuläre phase verabreichte lh zur behandlung von anovulatorischen frauen |
RS32804A (en) * | 2001-10-22 | 2007-02-05 | Applied Research Systems Ars Holding N.V., | Gonadotrophins for folliculogenesis |
JP4913604B2 (ja) * | 2004-02-13 | 2012-04-11 | グリコトープ ゲーエムベーハー | 高活性糖タンパク質−製造条件、及びその効率的製造方法 |
WO2008028686A2 (en) * | 2006-09-10 | 2008-03-13 | Glycotope Gmbh | Use of human cells of myeloid leukaemia origin for expression of antibodies |
TWI488640B (zh) * | 2008-04-16 | 2015-06-21 | Ferring Int Ct Sa | 藥學製劑 |
GB2459641B (en) * | 2008-04-16 | 2012-06-27 | Ubiquisys Ltd | Basestation power control |
EP2325194A1 (en) | 2009-11-24 | 2011-05-25 | Glycotope GmbH | Process for the purification of glycoproteins |
WO2012016576A1 (en) | 2010-08-04 | 2012-02-09 | Glycotope Gmbh | Improved recombinant human follicle-stimulating hormone |
-
2010
- 2010-08-04 WO PCT/EP2010/004769 patent/WO2012016576A1/en active Application Filing
-
2011
- 2011-08-04 CN CN201610363950.XA patent/CN106146646A/zh active Pending
- 2011-08-04 EA EA201390194A patent/EA029955B1/ru not_active IP Right Cessation
- 2011-08-04 EP EP11757190.1A patent/EP2601210B1/en not_active Revoked
- 2011-08-04 AU AU2011287525A patent/AU2011287525B2/en not_active Ceased
- 2011-08-04 JP JP2013522259A patent/JP6001534B2/ja not_active Expired - Fee Related
- 2011-08-04 SG SG2012093191A patent/SG186755A1/en unknown
- 2011-08-04 WO PCT/EP2011/063492 patent/WO2012017058A1/en active Application Filing
- 2011-08-04 SI SI201130854A patent/SI2601210T1/sl unknown
- 2011-08-04 HU HUE11757190A patent/HUE028357T2/en unknown
- 2011-08-04 ES ES11757190.1T patent/ES2576868T3/es active Active
- 2011-08-04 PT PT117571901T patent/PT2601210T/pt unknown
- 2011-08-04 NZ NZ604877A patent/NZ604877A/en not_active IP Right Cessation
- 2011-08-04 CN CN201180037096.3A patent/CN103068839B/zh active Active
- 2011-08-04 PL PL11757190.1T patent/PL2601210T3/pl unknown
- 2011-08-04 AR ARP110102828A patent/AR082852A1/es unknown
- 2011-08-04 BR BR112013004051A patent/BR112013004051A2/pt not_active Application Discontinuation
- 2011-08-04 CA CA2805134A patent/CA2805134C/en not_active Expired - Fee Related
- 2011-08-04 ES ES16168841T patent/ES2764083T3/es active Active
- 2011-08-04 RS RS20160459A patent/RS54905B1/sr unknown
- 2011-08-04 MX MX2013000500A patent/MX336489B/es unknown
- 2011-08-04 KR KR1020137005553A patent/KR20130136448A/ko not_active Application Discontinuation
- 2011-08-04 DK DK11757190.1T patent/DK2601210T3/en active
- 2011-08-04 US US13/814,059 patent/US9527899B2/en active Active
- 2011-08-04 EP EP16168841.1A patent/EP3075744B1/en not_active Revoked
-
2012
- 2012-12-12 ZA ZA2012/09436A patent/ZA201209436B/en unknown
- 2012-12-25 IL IL223867A patent/IL223867B/en active IP Right Grant
-
2013
- 2013-02-04 CU CU2013000019A patent/CU24043B1/es active IP Right Grant
-
2016
- 2016-06-13 HR HRP20160671TT patent/HRP20160671T1/hr unknown
- 2016-06-16 CY CY20161100539T patent/CY1117778T1/el unknown
- 2016-06-24 JP JP2016125181A patent/JP2016168055A/ja not_active Withdrawn
- 2016-07-06 SM SM201600219T patent/SMT201600219B/it unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant of patent |