MX2023008105A - Variante de proteina glxr o metodo de produccion de treonina usando la misma. - Google Patents

Variante de proteina glxr o metodo de produccion de treonina usando la misma.

Info

Publication number
MX2023008105A
MX2023008105A MX2023008105A MX2023008105A MX2023008105A MX 2023008105 A MX2023008105 A MX 2023008105A MX 2023008105 A MX2023008105 A MX 2023008105A MX 2023008105 A MX2023008105 A MX 2023008105A MX 2023008105 A MX2023008105 A MX 2023008105A
Authority
MX
Mexico
Prior art keywords
glxr
protein variant
same
production method
threonine production
Prior art date
Application number
MX2023008105A
Other languages
English (en)
Inventor
Kwang Woo Lee
Su Yon Kwon
Jihyun Shim
Yee- Seul So
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of MX2023008105A publication Critical patent/MX2023008105A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15—Corynebacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente solicitud se refiere a una variante de proteína GlxR o a un método de producción de treonina usando la misma, y la variante de proteína GlxR según una realización se introduce en un microorganismo para reducir la producción de subproductos y aumentar notablemente la capacidad de producción de treonina.
MX2023008105A 2021-01-11 2022-01-06 Variante de proteina glxr o metodo de produccion de treonina usando la misma. MX2023008105A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020210003609A KR102527895B1 (ko) 2021-01-11 2021-01-11 GlxR 단백질 변이체 또는 이를 이용한 쓰레오닌 생산방법
PCT/KR2022/000204 WO2022149865A2 (ko) 2021-01-11 2022-01-06 GlxR 단백질 변이체 또는 이를 이용한 쓰레오닌 생산방법

Publications (1)

Publication Number Publication Date
MX2023008105A true MX2023008105A (es) 2023-07-17

Family

ID=82358248

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023008105A MX2023008105A (es) 2021-01-11 2022-01-06 Variante de proteina glxr o metodo de produccion de treonina usando la misma.

Country Status (7)

Country Link
EP (1) EP4276107A2 (es)
KR (1) KR102527895B1 (es)
CN (1) CN116888141A (es)
AR (1) AR124580A1 (es)
AU (1) AU2022206623B2 (es)
MX (1) MX2023008105A (es)
WO (1) WO2022149865A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116120409B (zh) * 2022-11-03 2023-09-26 华南理工大学 一种imp生物传感器及其构建方法与应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1362866A1 (en) * 2002-05-16 2003-11-19 Basf Aktiengesellschaft Use of the repressor glxR for the synthesis of lysine in Corynebacterium glutamicum
DE10359661A1 (de) * 2003-12-18 2005-07-28 Basf Ag Genvarianten die für Proteine aus dem Stoffwechselweg von Feinchemikalien codieren
KR100924065B1 (ko) 2006-09-15 2009-10-27 씨제이제일제당 (주) Ｌ－라이신 생산능이 향상된 코리네박테리아 및 그를 이용한 ｌ－라이신 생산 방법
KR100858913B1 (ko) * 2007-03-09 2008-09-17 한국과학기술원 부위특이적 변이에 의해 제조된 고수율의 ｌ－쓰레오닌생산균주 및 이를 이용한 ｌ－쓰레오닌의 제조방법
KR101270149B1 (ko) * 2009-11-25 2013-06-04 한국과학기술원 Ｌ­이소루신 고생성능을 가지는 변이미생물 및 이의 제조방법
HUE050610T2 (hu) 2014-09-05 2021-01-28 Cj Cheiljedang Corp Javított L-treonin termelésére képes mikroorganizmus, és eljárás L-treonin elõállítására annak alkalmazásával
KR101947959B1 (ko) 2018-05-28 2019-02-13 씨제이제일제당 (주) 변이형 호모세린 디하이드로게나제 및 이를 이용한 호모세린 또는 호모세린 유래 l-아미노산의 생산 방법
EP3904521A4 (en) * 2018-12-26 2022-03-23 Daesang Corporation L-AMINO ACID-PRODUCING VARIANT STRAIN OF E. COLI OR CORYNEBACTERIUM GLUTAMICUM, AND METHODS OF PREPARATION OF L-AMINO ACIDS USING THE SAME
KR102221040B1 (ko) * 2019-05-09 2021-03-03 씨제이제일제당 주식회사 L-아미노산을 생산하는 미생물 및 이를 이용한 l-아미노산을 생산하는 방법

Also Published As

Publication number Publication date
WO2022149865A2 (ko) 2022-07-14
CN116888141A (zh) 2023-10-13
WO2022149865A3 (ko) 2022-08-25
EP4276107A2 (en) 2023-11-15
AU2022206623B2 (en) 2024-01-04
KR102527895B1 (ko) 2023-04-28
AR124580A1 (es) 2023-04-12
KR20220101509A (ko) 2022-07-19
AU2022206623A1 (en) 2023-06-29
JP2024503049A (ja) 2024-01-24

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