MX2023000192A - Particulas conjugadas con peptidos. - Google Patents
Particulas conjugadas con peptidos.Info
- Publication number
- MX2023000192A MX2023000192A MX2023000192A MX2023000192A MX2023000192A MX 2023000192 A MX2023000192 A MX 2023000192A MX 2023000192 A MX2023000192 A MX 2023000192A MX 2023000192 A MX2023000192 A MX 2023000192A MX 2023000192 A MX2023000192 A MX 2023000192A
- Authority
- MX
- Mexico
- Prior art keywords
- particles
- peptide conjugated
- conjugated particles
- peptide
- plg
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
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- A61K39/385—Haptens or antigens, bound to carriers
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- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
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- Public Health (AREA)
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- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Diabetes (AREA)
- Mycology (AREA)
- Microbiology (AREA)
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- Hematology (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
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- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Optics & Photonics (AREA)
- Emergency Medicine (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La presente invención proporciona composiciones que comprenden partículas biodegradables con superficie funcionalizada que comprenden un antígeno encapsulado o uno o más epítopos antigénicos, en donde la partícula tiene un potencial zeta negativo de - 30 mV a -80 mV. En una modalidad particular de la invención, la partícula es una partícula de poliestireno, una partícula de poliestireno carboxilado, una partícula de sulfuro de polipropileno estabilizado PLURIONICS, una partícula de poli (ácido láctico-co-glicólico), una partícula de poli (ácido láctico) (PLA), o una partícula de poli (ácido glicólico) (PGA). En otra modalidad particular de la invención, el antígeno comprende un antígeno autoinmunitario, un antígeno expresado en un tejido que se trasplantará a un sujeto, o una enzima para terapia de reemplazo de enzimas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361865389P | 2013-08-13 | 2013-08-13 | |
US201361869279P | 2013-08-23 | 2013-08-23 | |
US201361887112P | 2013-10-04 | 2013-10-04 |
Publications (1)
Publication Number | Publication Date |
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MX2023000192A true MX2023000192A (es) | 2023-02-09 |
Family
ID=52468804
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016001931A MX2016001931A (es) | 2013-08-13 | 2014-08-13 | Particulas conjugadas con peptidos. |
MX2020007079A MX2020007079A (es) | 2013-08-13 | 2016-02-12 | Particulas conjugadas con peptidos. |
MX2023000192A MX2023000192A (es) | 2013-08-13 | 2016-02-12 | Particulas conjugadas con peptidos. |
MX2023000194A MX2023000194A (es) | 2013-08-13 | 2016-02-12 | Particulas conjugadas con peptidos. |
MX2020004799A MX2020004799A (es) | 2013-08-13 | 2016-02-12 | Particulas conjugadas con peptidos. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016001931A MX2016001931A (es) | 2013-08-13 | 2014-08-13 | Particulas conjugadas con peptidos. |
MX2020007079A MX2020007079A (es) | 2013-08-13 | 2016-02-12 | Particulas conjugadas con peptidos. |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2023000194A MX2023000194A (es) | 2013-08-13 | 2016-02-12 | Particulas conjugadas con peptidos. |
MX2020004799A MX2020004799A (es) | 2013-08-13 | 2016-02-12 | Particulas conjugadas con peptidos. |
Country Status (24)
Country | Link |
---|---|
US (9) | US9616113B2 (es) |
EP (2) | EP3033102B2 (es) |
JP (4) | JP6553033B2 (es) |
KR (5) | KR20160042079A (es) |
CN (2) | CN105555301B (es) |
AU (4) | AU2014306603B2 (es) |
BR (1) | BR112016003084A2 (es) |
CA (1) | CA2918823A1 (es) |
CY (1) | CY1122558T1 (es) |
DK (1) | DK3033102T4 (es) |
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