MX2022000253A - Proceso de fermentacion industrial para celulas microbianas mediante el uso de un precultivo de alimentacion por lotes. - Google Patents

Proceso de fermentacion industrial para celulas microbianas mediante el uso de un precultivo de alimentacion por lotes.

Info

Publication number
MX2022000253A
MX2022000253A MX2022000253A MX2022000253A MX2022000253A MX 2022000253 A MX2022000253 A MX 2022000253A MX 2022000253 A MX2022000253 A MX 2022000253A MX 2022000253 A MX2022000253 A MX 2022000253A MX 2022000253 A MX2022000253 A MX 2022000253A
Authority
MX
Mexico
Prior art keywords
culture
fed
microbial cells
fermentation process
industrial fermentation
Prior art date
Application number
MX2022000253A
Other languages
English (en)
Inventor
Andreas Daub
Anbarani Aydin Golabgir
Tobias Klein
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of MX2022000253A publication Critical patent/MX2022000253A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01001—Alpha-amylase (3.2.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2511/00—Cells for large scale production

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La invención se refiere a un proceso para cultivar células microbianas que producen un producto de interés que comprende un precultivo de alimentación por lotes.
MX2022000253A 2019-07-05 2020-06-30 Proceso de fermentacion industrial para celulas microbianas mediante el uso de un precultivo de alimentacion por lotes. MX2022000253A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19184580 2019-07-05
EP20170663 2020-05-05
PCT/EP2020/068335 WO2021004830A1 (en) 2019-07-05 2020-06-30 Industrial fermentation process for microbial cells using a fed-batch pre-culture

Publications (1)

Publication Number Publication Date
MX2022000253A true MX2022000253A (es) 2022-02-03

Family

ID=71130990

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022000253A MX2022000253A (es) 2019-07-05 2020-06-30 Proceso de fermentacion industrial para celulas microbianas mediante el uso de un precultivo de alimentacion por lotes.

Country Status (7)

Country Link
US (1) US20230212506A1 (es)
EP (1) EP3959326B1 (es)
CN (1) CN114096677A (es)
ES (1) ES2955800T3 (es)
MX (1) MX2022000253A (es)
PL (1) PL3959326T3 (es)
WO (1) WO2021004830A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113186232B (zh) * 2021-06-15 2023-11-17 南京林业大学 一种利用恶臭假单胞菌和凝结芽孢杆菌共培养发酵生产乳酸的方法
CN114395503B (zh) * 2021-12-06 2023-08-22 湖北工业大学 一种地衣芽胞杆菌高细胞密度和/或高芽胞量的发酵方法
CN115948622B (zh) * 2022-09-22 2024-08-09 北京蓝晶微生物科技有限公司 微生物发酵控制方法、装置、系统、设备及介质
CN116179454A (zh) * 2022-10-27 2023-05-30 天津科技大学 一种甘蔗渣为原料发酵生产乳酸单体的重组菌及其应用
PL443706A1 (pl) * 2023-02-07 2024-08-12 Green Tree Group Spółka Z Ograniczoną Odpowiedzialnością Sposób otrzymywania płynnego środka i sposób biodegradacji termoplastycznych materiałów polimerowych w kompoście
CN117904004B (zh) * 2024-03-13 2024-05-14 齐鲁工业大学(山东省科学院) 一株耐盐芽孢杆菌及其在降解类胡萝卜素上的应用

Family Cites Families (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA888690A (en) 1966-04-25 1971-12-21 B. Mccarty Charles Enzyme-containing detergent compositions
BE759002R (fr) 1969-11-19 1971-05-17 Knapsack Ag Procede de preparation de granules contenant des
JPS6128381A (ja) * 1984-07-20 1986-02-08 Riyoushiyoku Kenkyukai 工業微生物の高濃度培養法
ES2135386T3 (es) 1987-02-27 1999-11-01 Genencor Int Transformacion de cepas de bacillus alcalofilas.
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
DK0493398T3 (da) 1989-08-25 2000-05-22 Henkel Research Corp Alkalisk, proteolytisk enzym og fremgangsmåde til fremstilling deraf
DE69226182T2 (de) 1991-05-01 1999-01-21 Novo Nordisk A/S, Bagsvaerd Stabilisierte enzyme und waschmittelzusammensetzungen
KR100294361B1 (ko) 1992-07-23 2001-09-17 피아 스타르 돌연변이체알파-아밀라제,세정제,접시세척제,및액화제
JPH08506491A (ja) 1993-02-11 1996-07-16 ジェネンカー インターナショナル，インコーポレイティド 酸化安定性アルファ−アミラーゼ
AU6267694A (en) 1993-02-26 1994-09-14 Procter & Gamble Company, The High active enzyme granulates
JPH09503916A (ja) 1993-10-08 1997-04-22 ノボ ノルディスク アクティーゼルスカブ アミラーゼ変異体
ES2302330T3 (es) 1994-02-24 2008-07-01 Henkel Kommanditgesellschaft Auf Aktien Enzimas mejoradas y detergentes que las contienen.
AU2067795A (en) 1994-03-29 1995-10-17 Novo Nordisk A/S Alkaline bacillus amylase
EP0807168A1 (en) 1995-02-02 1997-11-19 Stichting Centraal Laboratorium van de Bloedtransfusiedienst van het Nederlandse Rode Kruis Enrichment of hematopoietic stem cells from blood or bone marrow
ATE432342T1 (de) 1995-02-03 2009-06-15 Novozymes As Eine methode zum entwurf von alpha-amylase mutanten mit vorbestimmten eigenschaften
KR100380006B1 (ko) 1995-05-05 2004-05-27 노보자임스 에이/에스 프로테아제변이체와조성물
WO1997025417A1 (en) 1996-01-11 1997-07-17 Recombinant Biocatalysis, Inc. Glycosidase enzymes
DE19619221A1 (de) 1996-05-13 1997-11-20 Solvay Enzymes Gmbh & Co Kg Enzymgranulat für Wasch- und Reinigungsanwendungen
US5763385A (en) 1996-05-14 1998-06-09 Genencor International, Inc. Modified α-amylases having altered calcium binding properties
KR100561826B1 (ko) 1996-11-04 2006-03-16 노보자임스 에이/에스 섭틸라제 변종과 조성물
CA2270180C (en) 1996-11-04 2011-01-11 Novo Nordisk A/S Subtilase variants and compositions
US7279316B2 (en) 1996-12-06 2007-10-09 Verenium Corporation Enzymes having glycosidase activity and methods of use thereof
ATE295850T1 (de) 1996-12-06 2005-06-15 Diversa Corp Glycosidase-enzyme
ATE385254T1 (de) 1997-08-29 2008-02-15 Novozymes As Proteasevarianten und zusammensetzungen
AR017331A1 (es) 1997-10-13 2001-09-05 Novozymes As Polipeptidos mutantes de alfa-amilasas, aditivo para detergentes y composiciones detergentes que los comprenden.
WO1999027083A1 (en) 1997-11-24 1999-06-03 Novo Nordisk A/S PECTIN DEGRADING ENZYMES FROM $i(BACILLUS LICHENIFORMIS)
US6124127A (en) 1997-11-24 2000-09-26 Novo Nordisk A/S Pectate lyase
KR20010032382A (ko) 1997-11-24 2001-04-16 피아 스타르 신규한 펙테이트 리아제
CN100497614C (zh) 1998-06-10 2009-06-10 诺沃奇梅兹有限公司 甘露聚糖酶
EP1121424A1 (en) 1998-10-13 2001-08-08 Novozymes A/S A modified polypeptide with reduced immune response
NZ511340A (en) 1998-11-27 2003-07-25 Novozymes As Lipolytic enzyme variants
US6316240B1 (en) 1999-01-25 2001-11-13 Novozymes A/S Recovery of a glycosidase or peptidase from a culture broth at high pH
EP2889375B1 (en) 1999-03-31 2019-03-20 Novozymes A/S Polypeptides having alkaline alpha-amylase activity and nucleic acids encoding same
CN1415011B (zh) 1999-12-15 2010-12-08 诺沃奇梅兹有限公司 对蛋渍具有改进洗涤性能的枯草杆菌酶变体
EP1263942B1 (en) 2000-03-08 2013-11-06 Novozymes A/S Variants with altered properties
CN1230530C (zh) 2000-07-19 2005-12-07 诺和酶股份有限公司 细胞壁降解酶变体
AU2001278415A1 (en) 2000-08-01 2002-02-13 Novozymes A/S Alpha-amylase mutants with altered stability
DE10064983A1 (de) 2000-12-23 2002-07-18 Henkel Kgaa Neue Alkalische Protease aus Bacillus alcalophilus (DSM 11233)
US7323336B2 (en) 2001-02-21 2008-01-29 Verenium Corporation Enzymes having alpha amylase activity and methods of use thereof
CN101724640B (zh) 2001-02-21 2014-10-15 维莱尼姆公司 具有α淀粉酶活性的酶及其使用方法
DE10121463A1 (de) 2001-05-02 2003-02-27 Henkel Kgaa Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten
EP1389228B1 (en) 2001-05-14 2009-03-11 Novozymes A/S Detergent compositions comprising bacillus subtilis pectate lyases
DK200101090A (da) 2001-07-12 2001-08-16 Novozymes As Subtilase variants
DE10162728A1 (de) 2001-12-20 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus gibsonii (DSM 14393) und Wasch-und Reinigungsmittel enthaltend diese neue Alkalische Protease
DE10163883A1 (de) 2001-12-22 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus sp. (DSM 14390) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease
DE10163884A1 (de) 2001-12-22 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus sp. (DSM 14392) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease
US7226771B2 (en) 2002-04-19 2007-06-05 Diversa Corporation Phospholipases, nucleic acids encoding them and methods for making and using them
EP2298871A1 (en) 2002-04-19 2011-03-23 Verenium Corporation Phospholipases, nucleic acids encoding them and methods for making and using them
JP4523404B2 (ja) 2002-05-14 2010-08-11 ノボザイムス アクティーゼルスカブ ペクチン酸リアーゼ変異体
WO2004003186A2 (en) 2002-06-26 2004-01-08 Novozymes A/S Subtilases and subtilase variants having altered immunogenicity
CN1665924A (zh) 2002-07-01 2005-09-07 诺维信公司 水解氮源
TWI319007B (en) 2002-11-06 2010-01-01 Novozymes As Subtilase variants
DE10304331B4 (de) 2003-02-04 2017-12-28 Henkel Ag & Co. Kgaa Enzymatische Entfernung von Biofilmen auf Haushaltsoberflächen
CA2515340C (en) 2003-03-06 2016-04-26 Diversa Corporation Amylases, nucleic acids encoding them and methods for making and using them
CA3007908A1 (en) 2003-03-07 2005-04-14 Dsm Ip Assets B.V. Hydrolases, nucleic acids encoding them and methods for making and using them
ES2545639T3 (es) 2003-04-04 2015-09-14 Basf Enzymes Llc Pectato liasas, ácidos nucleicos que las codifican y métodos para su preparación y uso
AU2004254640B2 (en) 2003-07-02 2010-08-26 Bp Corporation North America Inc. Glucanases, nucleic acids encoding them and methods for making and using them
DE10360805A1 (de) 2003-12-23 2005-07-28 Henkel Kgaa Neue Alkalische Protease und Wasch- und Reinigungsmittel, enthaltend diese neue Alkalische Protease
DE102004019751A1 (de) 2004-04-23 2005-11-17 Henkel Kgaa Neue Alkalische Proteasen und Wasch- und Reinigungsmittel, enthaltend diese neuen Alkalischen Proteasen
EP1762008A1 (en) 2004-06-24 2007-03-14 Koninklijke Philips Electronics N.V. Zero power radio
EP3620523A3 (en) 2004-07-05 2020-08-19 Novozymes A/S Alpha-amylase variants with altered properties
WO2006031699A2 (en) 2004-09-10 2006-03-23 Diversa Corporation Compositions and methods for making and modifying oils
AU2005318696B2 (en) 2004-12-23 2010-12-16 Novozymes A/S Alpha-amylase variants
CN103555697A (zh) 2005-07-08 2014-02-05 诺维信公司 枯草蛋白酶变体
DK2069389T3 (en) 2006-08-04 2015-01-12 Bp Corp North America Inc Glucanases, nucleic acids encoding them, and processes for their preparation and use
MX2009003034A (es) 2006-09-21 2009-11-18 Verenium Corp Fosfolipasas, acidos nucleicos que las codifican, y metodos de hacerlas y usarlas.
CN101646767B (zh) 2006-12-21 2013-05-29 先正达参股股份有限公司 淀粉酶和葡糖淀粉酶、编码其的核酸以及关于制备和使用其的方法
WO2008110498A1 (en) 2007-03-15 2008-09-18 Novozymes A/S Solubilization of protease crystals in fermentation broth
NZ584434A (en) 2007-11-05 2011-12-22 Danisco Us Inc VARIANTS OF BACILLUS sp. TS-23 ALPHA-AMYLASE WITH ALTERED PROPERTIES
WO2010104675A1 (en) 2009-03-10 2010-09-16 Danisco Us Inc. Bacillus megaterium strain dsm90-related alpha-amylases, and methods of use, thereof
JP5947213B2 (ja) 2009-09-25 2016-07-06 ノボザイムス アクティーゼルスカブ プロテアーゼ変異体の使用
AU2010299800B2 (en) 2009-09-25 2014-08-07 Novozymes A/S Use of protease variants
UA109884C2 (uk) 2009-10-16 2015-10-26 Поліпептид, що має активність ферменту фосфатидилінозитол-специфічної фосфоліпази с, нуклеїнова кислота, що його кодує, та спосіб його виробництва і застосування
CA2782891C (en) 2009-12-09 2022-01-11 Danisco Us Inc. Compositions and methods comprising protease variants
EP3892709A3 (en) 2010-02-10 2022-01-19 Novozymes A/S Variants and compositions comprising variants with high stability in presence of a chelating agent
CN103703124B (zh) 2011-06-30 2021-01-15 诺维信公司 用于筛选α-淀粉酶的方法
EP3798303A1 (en) 2011-06-30 2021-03-31 Novozymes A/S Alpha-amylase-variants
ES2909509T3 (es) 2012-06-08 2022-05-06 Danisco Us Inc Variante de alfa-amilasas con mayor actividad en polímeros de almidón
CN110093330B (zh) 2012-10-12 2023-11-28 丹尼斯科美国公司 包含脂解酶变体的组合物和方法
CN104561139A (zh) * 2013-10-18 2015-04-29 中国石油化工股份有限公司 一种提高微生物终细胞密度并缩短培养时间的方法
CN103805582B (zh) * 2013-12-27 2017-02-01 湖南鸿鹰生物科技有限公司 一种含有β‑葡聚糖酶的生长猪专用酶及其制备方法
CN106164236B (zh) 2014-04-11 2021-02-02 诺维信公司 洗涤剂组合物
US20170152462A1 (en) 2014-04-11 2017-06-01 Novozymes A/S Detergent Composition
WO2015166075A1 (en) 2014-05-02 2015-11-05 Novozymes A/S Detergent composition
WO2015181286A1 (en) 2014-05-28 2015-12-03 Novozymes A/S Use of polypeptide
CN106795463B (zh) 2014-05-28 2020-09-29 诺维信公司 用于减少静电的具有dna酶活性的多肽
CN107002058A (zh) 2014-12-15 2017-08-01 诺维信公司 枯草杆菌酶变体
CA3005292A1 (en) * 2015-12-09 2017-06-15 Basf Se Method of purifying a protein from fermentation solids under desorbing conditions

Also Published As

Publication number Publication date
WO2021004830A1 (en) 2021-01-14
EP3959326B1 (en) 2023-06-07
CN114096677A (zh) 2022-02-25
ES2955800T3 (es) 2023-12-07
US20230212506A1 (en) 2023-07-06
PL3959326T3 (pl) 2023-10-09
EP3959326C0 (en) 2023-06-07
EP3959326A1 (en) 2022-03-02

Similar Documents

Publication Publication Date Title
MX2022000253A (es) Proceso de fermentacion industrial para celulas microbianas mediante el uso de un precultivo de alimentacion por lotes.
PH12020550441A1 (en) Fermentative production of n-acetylneuraminic acid
WO2018124440A3 (ko) 신규한 이소프로필말레이트 신타제 변이체 및 이를 이용한 l-류신의 생산 방법
MX2021003955A (es) Levadura que expresa enzimas para la produccion de etanol.
MX2018002705A (es) Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas.
AU2019262112A8 (en) Engineered microorganism for the production of cannabinoid biosynthetic pathway products
MX2019014142A (es) Levadura mejorada para produccion de etanol.
AU2018271755A1 (en) Method for culturing natural killer cell, using transformed T cell
AU2019222480A8 (en) Improved yeast for ethanol production
WO2016171224A9 (ja) タンパク質の分泌生産法
EP4249221A3 (en) Double diaphragm shaping of composite materials, assemblies for such shaping, and resulting composite materials
EP3914696A4 (en) SEED CULTIVATION METHOD FOR THE PRODUCTION OF AAV
MX2020013565A (es) Produccion microbiana de dioles grasos.
WO2018203947A3 (en) MODIFIED BIOSYNTHESIS PATHWAYS FOR FERMENTATION TYRAMINE PRODUCTION
PH12016501272A1 (en) Process for degrading mannan-containing cellulosic materials
MX2018014764A (es) Metodo para producir acido 3-hidroxiadipico.
WO2016012445A3 (en) Process for the purification of poliovirus from cell cultures
EP3778880A4 (en) Method for large-scale production of lentivirus by using gmp-level serum-free suspension cells
MX2018004580A (es) Metodo para producir proteina de fusion con dominio fc de igg.
MX2018014769A (es) Metodo para producir acido a-hidromuconico.
WO2018131898A3 (ko) 메틸로모나스 속 dh-1 균주의 신규한 용도
MX2021008301A (es) Proceso de purificacion de ficocianinas.
PH12020551791A1 (en) Methods for the production of methacrylates
MX2017012554A (es) Microalgas adaptadas para condiciones de cultivo heterotrofo.
MX2020010348A (es) Proceso para la fermentacion de ascomycota.