MX2021012268A - Composicion autoemulsionante de farmacos polifenolicos flavonoides, metodo de preparacion de la misma, composicion farmaceutica de la misma y aplicacion de la misma. - Google Patents

Composicion autoemulsionante de farmacos polifenolicos flavonoides, metodo de preparacion de la misma, composicion farmaceutica de la misma y aplicacion de la misma.

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Publication number
MX2021012268A
MX2021012268A MX2021012268A MX2021012268A MX2021012268A MX 2021012268 A MX2021012268 A MX 2021012268A MX 2021012268 A MX2021012268 A MX 2021012268A MX 2021012268 A MX2021012268 A MX 2021012268A MX 2021012268 A MX2021012268 A MX 2021012268A
Authority
MX
Mexico
Prior art keywords
composition
flavonoid polyphenol
preparation
application
method therefor
Prior art date
Application number
MX2021012268A
Other languages
English (en)
Inventor
Yuling Liu
Hengfeng Liao
Yue Gao
Wujun Dong
Zhihua Liu
Bangyuan Wang
Yun Zhang
Yu Feng
Junzhuo Zhou
Lu Liu
Jun Ye
Yanfang Yang
Xuejun Xia
Original Assignee
Beijing Wehand Bio Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Wehand Bio Pharmaceutical Co Ltd filed Critical Beijing Wehand Bio Pharmaceutical Co Ltd
Publication of MX2021012268A publication Critical patent/MX2021012268A/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
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    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
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    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
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    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
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Abstract

Una composición autoemulsionante de un fármaco polifenólico flavonoide basada en un complejo polifenólico fiavonoide-fosfolípido que se utiliza como intermediario, la composición que comprende un complejo polifenólico flavonoide-fosfolípido, una fase oleosa, un emulsionante y un coemulsionante, el fármaco polifenólico flavonoide que comprende uno o más seleccionados entre baicaleina, proantocianidina, quercetina, curcumina y resveratrol. La composición autoemulsionante descrita tiene los efectos beneficiosos de una buena estabilidad, una alta cantidad de carga de fármaco, una alta biodisponibilidad, etc.
MX2021012268A 2019-04-09 2020-04-08 Composicion autoemulsionante de farmacos polifenolicos flavonoides, metodo de preparacion de la misma, composicion farmaceutica de la misma y aplicacion de la misma. MX2021012268A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201910278955.6A CN111803632B (zh) 2019-04-09 2019-04-09 黄酮多酚类药物自乳化组合物、其制备方法、药物组合物及用途
PCT/CN2020/083837 WO2020207417A1 (zh) 2019-04-09 2020-04-08 黄酮多酚类药物自乳化组合物、其制备方法、药物组合物及用途

Publications (1)

Publication Number Publication Date
MX2021012268A true MX2021012268A (es) 2022-01-04

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MX2021012268A MX2021012268A (es) 2019-04-09 2020-04-08 Composicion autoemulsionante de farmacos polifenolicos flavonoides, metodo de preparacion de la misma, composicion farmaceutica de la misma y aplicacion de la misma.

Country Status (12)

Country Link
US (1) US11771660B2 (es)
EP (1) EP3954380A4 (es)
JP (1) JP2022530752A (es)
KR (1) KR102497718B1 (es)
CN (2) CN111803632B (es)
AU (1) AU2020256609B2 (es)
BR (1) BR112021020359A2 (es)
CA (1) CA3132454C (es)
MX (1) MX2021012268A (es)
SG (1) SG11202111116VA (es)
WO (1) WO2020207417A1 (es)
ZA (1) ZA202108771B (es)

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CN107007569B (zh) * 2017-03-23 2019-08-30 徐州医科大学 一种载槲皮素和白藜芦醇的磁性脂质纳米粒及其制备方法

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