MX2021005992A - Gaboxadol para reducir el riesgo de suicidio y para alivio rápido de la depresión. - Google Patents

Gaboxadol para reducir el riesgo de suicidio y para alivio rápido de la depresión.

Info

Publication number
MX2021005992A
MX2021005992A MX2021005992A MX2021005992A MX2021005992A MX 2021005992 A MX2021005992 A MX 2021005992A MX 2021005992 A MX2021005992 A MX 2021005992A MX 2021005992 A MX2021005992 A MX 2021005992A MX 2021005992 A MX2021005992 A MX 2021005992A
Authority
MX
Mexico
Prior art keywords
depression
gaboxadol
suicide
reducing risk
rapid relief
Prior art date
Application number
MX2021005992A
Other languages
English (en)
Spanish (es)
Inventor
Pavel Osten
Kristin Baldwin
Original Assignee
Certego Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Certego Therapeutics Inc filed Critical Certego Therapeutics Inc
Publication of MX2021005992A publication Critical patent/MX2021005992A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
MX2021005992A 2018-11-21 2019-11-21 Gaboxadol para reducir el riesgo de suicidio y para alivio rápido de la depresión. MX2021005992A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862770287P 2018-11-21 2018-11-21
PCT/US2019/062554 WO2020106927A1 (en) 2018-11-21 2019-11-21 Gaboxadol for reducing risk of suicide and rapid relief of depression

Publications (1)

Publication Number Publication Date
MX2021005992A true MX2021005992A (es) 2021-09-14

Family

ID=70728606

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021005992A MX2021005992A (es) 2018-11-21 2019-11-21 Gaboxadol para reducir el riesgo de suicidio y para alivio rápido de la depresión.

Country Status (13)

Country Link
US (3) US20220008398A1 (zh)
EP (1) EP3883566A4 (zh)
JP (1) JP2022514194A (zh)
KR (1) KR20210110585A (zh)
CN (1) CN113395962A (zh)
AU (1) AU2019384157A1 (zh)
BR (1) BR112021009944A2 (zh)
CA (1) CA3120856A1 (zh)
GB (1) GB2594616A (zh)
IL (1) IL283311A (zh)
MX (1) MX2021005992A (zh)
SG (1) SG11202105358RA (zh)
WO (1) WO2020106927A1 (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2015002252A (es) 2012-08-21 2015-07-21 Sage Therapeutics Inc Metodos para tratar epilepsia o estado de epilepsia.
JOP20200195A1 (ar) 2014-09-08 2017-06-16 Sage Therapeutics Inc سترويدات وتركيبات نشطة عصبياً، واستخداماتها
IL300422A (en) 2016-03-08 2023-04-01 Sage Therapeutics Inc Neuroactive steroids, preparations and their uses
WO2018031748A1 (en) * 2016-08-11 2018-02-15 Ovid Therapeutics Inc. Methods and compositions for treatment of epileptic disorders
US10071083B2 (en) * 2017-02-03 2018-09-11 Ovid Therapeutics Inc Use of gaboxadol in the treatment of tinnitus
US20220008398A1 (en) * 2018-11-21 2022-01-13 Certego Therapeutics Gaboxadol for reducing risk of suicide and rapid relief of depression
KR20230028244A (ko) 2020-05-20 2023-02-28 썰테고 테라퓨틱스 아이엔씨. 고리 중수소화 가복사돌 및 정신 장애의 치료를 위한 이의 용도

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK270278A (da) 1977-06-20 1978-12-21 Krogsgaard Larsen P Cycliske aminosyrer
US4362731A (en) 1980-09-01 1982-12-07 Sandoz Ltd. Myotonolytic use of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridin-3-ol and derivatives thereof
US4353910A (en) 1981-11-27 1982-10-12 Kefalas A/S Derivatives of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridine-3-one, pharmaceutical compositions and methods of treatment
DE19525598C2 (de) 1995-07-13 1997-09-25 Max Planck Gesellschaft Schlafmittel
AR031473A1 (es) 2000-11-20 2003-09-24 Lundbeck & Co As H Intensificadores de gaba en el tratamiento de enfermedades relacionadas con una reducida actividad neuroesteroide
US20020165217A1 (en) 2001-05-01 2002-11-07 Pfizer Inc. Combination treatment for anxiety and depression
ATE459353T1 (de) 2003-06-25 2010-03-15 Lundbeck & Co As H Gaboxadol zur behandlung von depressionen und anderen affektiven störungen
TW200501951A (en) 2003-06-25 2005-01-16 Lundbeck & Co As H Treatment of neuropathic pain, fibromyalgia or rheumatoid arthritis
US20050234093A1 (en) 2003-06-25 2005-10-20 H. Lundbeck A/S Treatment of depression and other affective disorders
TW200509918A (en) 2003-06-25 2005-03-16 Lundbeck & Co As H Treatment of depression and other affective disorders
CL2004001603A1 (es) * 2003-06-25 2005-05-27 Lundbeck & Co As H Uso de gabaxadol para preparar un medicamento util para el tratamiento del dolor neuropatico.
AR045540A1 (es) 2003-09-05 2005-11-02 Lundbeck & Co As H Metodo de elaboracion de 4,5,6,7 tetrahidroisoxazol [5,4-c] piridin-3-ol (thip)
UY28650A1 (es) * 2003-12-05 2005-02-28 Forest Laboratories Memantina para la prevencion o disminucion de la conducta suicida y para el tratamiento de la depresion mayor asociada con esta conducta
US20050137222A1 (en) 2003-12-18 2005-06-23 H. Lundbeck A/S Treatment of insomnia in human patients
GB0402118D0 (en) 2004-01-30 2004-03-03 Merck Sharp & Dohme Polymorphic forms of a GABAA agonist
EA200601853A1 (ru) 2004-04-02 2007-02-27 Х. Лундбекк А/С Лечение нарушенной дыхательной функции
MXPA06011325A (es) 2004-04-02 2006-12-15 Lundbeck & Co As H Tratamiento de la funcion respiratoria alterada con gaboxadol.
GB0417558D0 (en) 2004-08-06 2004-09-08 Merck Sharp & Dohme Novel combination therapy
EP2292222A1 (en) 2005-01-28 2011-03-09 H. Lundbeck A/S Polymorphic Forms of a GABAA Agonist
EP1906953A4 (en) 2005-04-29 2009-05-20 Lundbeck & Co As H FORMS OF ACID SALTS AND BASIC SALTS OF GABOXADOL
DE102005020882A1 (de) 2005-05-04 2006-11-09 Dömling, Alexander, Dr. Verwendung von Gaboxadol und Derivaten zur Behandlung von Kinase-induzierten Krankheiten
FR2889811B1 (fr) 2005-08-19 2009-10-09 Sanofi Aventis Sa Association d'un agent hypnotique a duree d'action longue et d'un agent hypnotique a duree d'action courte, composition pharmaceutique la contenant et son application en therapeutique.
US8785500B2 (en) * 2006-03-22 2014-07-22 Icahn School Of Medicine At Mount Sinai Intranasal administration of ketamine to treat depression
US20080159958A1 (en) 2006-12-27 2008-07-03 Abbott Laboratories Determination of histamine-3 bioactivity
US20090048288A1 (en) 2007-08-13 2009-02-19 H. Lundbeck A/S Method of treating stress-mediated depression
TW200920358A (en) 2007-08-13 2009-05-16 Lundbeck & Co As H Method of treating stress-mediated depression
US20090143335A1 (en) 2007-10-29 2009-06-04 H. Lundbeck A/S Modified absorption formulation of gaboxadol
GB0810063D0 (en) 2008-06-03 2008-07-09 Renovo Ltd Medicaments and methods for inhibition of scarring
JP2012501301A (ja) 2008-09-01 2012-01-19 ハー・ルンドベック・アクチエゼルスカベット ガボキサドールおよびpat1阻害薬またはoat阻害薬を含む医薬組成物
WO2015153658A2 (en) * 2014-03-31 2015-10-08 University Of Maryland, Baltimore Use of negative modulators of gaba receptors containing alpha5 subunits as fast acting antidepressants
US20150313903A1 (en) 2014-05-05 2015-11-05 Ovid Therapeutics Inc. Methods of treating cognitive impairment associated with neurodegenerative disorders
MX2020012404A (es) 2014-06-06 2022-04-11 Ovid Therapeutics Inc Metodos para incrementar la inhibicion tonica y para tratar insomnio secundario.
US20170304358A1 (en) 2014-10-06 2017-10-26 Seyyed Nassir GHAEMI Primary and secondary prevention of dementias and suicide with trace dose lithium
JP6735284B2 (ja) 2015-03-24 2020-08-05 ハー・ルンドベック・アクチエゼルスカベット 4,5,6,7−テトラヒドロイソオキサゾロ[5,4−c]ピリジン−3−オールの製造
WO2016176609A1 (en) 2015-04-30 2016-11-03 Ovid Therapeutics Inc Methods of treating prader-willi syndrome
US9682069B2 (en) 2015-07-17 2017-06-20 Ovid Therapeutics Inc Methods of treating Dravet syndrome
PE20190338A1 (es) 2015-07-17 2019-03-07 Ovid Therapeutics Inc Metodos de tratamiento de trastornos del desarrollo con gaboxadol
US20170348232A1 (en) 2016-06-07 2017-12-07 Ovid Therapeutics Inc. Formulations of gaboxadol for treatment of angelman syndrome, fragile x syndrome and fragile x-associated tremor/ataxia syndrome
AR105378A1 (es) 2015-07-17 2017-09-27 Ovid Therapeutics Inc Métodos de tratamiento de trastornos del desarrollo con gaboxadol
US9399034B1 (en) 2015-08-11 2016-07-26 Ovid Therapeutics Inc Methods of sedation during critical care treatment
WO2017027249A1 (en) * 2015-08-11 2017-02-16 Ovid Therapeutics Inc. Methods of sedation and parenteral formulation for use during critical care treatment
CA2994952A1 (en) 2015-08-11 2017-02-16 Ovid Therapeutics Inc. Methods of sedation and parenteral formulation for use during critical care treatment
AR105670A1 (es) 2015-08-11 2017-10-25 Ovid Therapeutics Inc Métodos de sedación parenteral para usar durante el tratamiento de cuidados intensivos
US9351968B1 (en) 2015-09-09 2016-05-31 Ovid Therapeutics Inc Methods of treating developmental disorders using pipradrol
WO2017066421A1 (en) 2015-10-13 2017-04-20 Ovid Therapeutics Inc. Treatment of cognitive impairment
KR20190013737A (ko) 2016-05-26 2019-02-11 오비드 테라퓨틱스 인크. 피프라드롤을 이용한 행동 증후군들의 치료 방법들
WO2018031748A1 (en) 2016-08-11 2018-02-15 Ovid Therapeutics Inc. Methods and compositions for treatment of epileptic disorders
CA3043626A1 (en) 2016-11-22 2018-05-31 Ovid Therapeutics Inc. Methods of treating attention deficit/hyperactivity disorder with gaboxadol
US11535568B2 (en) 2016-11-30 2022-12-27 Hrl Laboratories, Llc Monomer formulations and methods for 3D printing of preceramic polymers
US10071083B2 (en) 2017-02-03 2018-09-11 Ovid Therapeutics Inc Use of gaboxadol in the treatment of tinnitus
JP2020511473A (ja) 2017-03-15 2020-04-16 オービッド・セラピューティクス・インコーポレイテッドOvid Therapeutics Inc. 発作性疾患の治療におけるデザイナー化合物によりのみ活性化するデザイナー受容体の使用
US20180338959A1 (en) 2017-05-24 2018-11-29 Ovid Therapeutics Inc. Treatment of depressive disorders
US20180344745A1 (en) 2017-06-01 2018-12-06 Ovid Therapeutics Inc. Treatment of developmental disorders with imidazolone derivatives
US20190000993A1 (en) 2017-06-28 2019-01-03 Ovid Therapeutics Inc. Treatment of developmental syndromes
EP3648762A4 (en) 2017-08-04 2021-03-24 Ovid Therapeutics, Inc. USE OF GABOXADOL IN THE TREATMENT OF DIABETES AND RELATED DISEASES
CN111163811A (zh) 2017-08-25 2020-05-15 奥维德医疗公司 重组腺相关载体
KR20200053570A (ko) 2017-09-12 2020-05-18 오비드 테라퓨틱스 인크. 기면증의 치료에서 가복사돌의 사용
CN107595850A (zh) 2017-10-25 2018-01-19 桂林浩新科技服务有限公司 一种有效提高睡眠质量的药物组合物及其用途
KR20210039324A (ko) 2018-04-06 2021-04-09 오비드 테라퓨틱스 인크. 물질 사용 장애들의 치료에서 가복사돌의 사용
US20220008398A1 (en) * 2018-11-21 2022-01-13 Certego Therapeutics Gaboxadol for reducing risk of suicide and rapid relief of depression

Also Published As

Publication number Publication date
WO2020106927A1 (en) 2020-05-28
US20220054461A1 (en) 2022-02-24
CA3120856A1 (en) 2020-05-28
US20220008398A1 (en) 2022-01-13
JP2022514194A (ja) 2022-02-10
CN113395962A (zh) 2021-09-14
SG11202105358RA (en) 2021-06-29
US11123332B2 (en) 2021-09-21
EP3883566A4 (en) 2022-09-07
EP3883566A1 (en) 2021-09-29
BR112021009944A2 (pt) 2021-08-17
GB202108720D0 (en) 2021-08-04
KR20210110585A (ko) 2021-09-08
US20200155522A1 (en) 2020-05-21
IL283311A (en) 2021-07-29
AU2019384157A1 (en) 2021-06-17
GB2594616A (en) 2021-11-03

Similar Documents

Publication Publication Date Title
MX2021005992A (es) Gaboxadol para reducir el riesgo de suicidio y para alivio rápido de la depresión.
MX2021004639A (es) Combinaciones de inhibidores de desmetilasa-1 especifica de lisina (lsd1) para uso en el tratamiento de tumores solidos.
MX2020009773A (es) Terapia de combinacion.
MX2018001435A (es) Metodos de tratamiento del sindrome de lennox-gastaut con fenfluramina.
MX2019013279A (es) Metodos de tratamiento del sindrome de doose utilizando fenfluramina.
PH12019500845A1 (en) Combinations comprising an ssao/vap-1 inhibitor and a sglt2 inhibitor, uses thereof
EP4324521A3 (en) Treatment of fabry disease in ert-naive and ert-experienced patients
MX2009008582A (es) Metodo para la administracion terapeutica de dihidroergotamina para permitir un rapido alivio de la migraña mientras se minimiza el perfil de efectos secundarios.
MX2024010140A (es) Nuevos metodos.
RU2017134443A (ru) Способ лечения с применением традипитанта
PH12018502422A1 (en) Nanoliposomal irinotecan for use in treating small cell lung cancer
MX2019003134A (es) Terapia de combinacion.
MX2020011295A (es) Tratamiento de dermatitis atopica.
MX2020001727A (es) Terapia de combinacion.
AU2018282104A1 (en) Use of vibegron to treat overactive bladder
MX2022003190A (es) Terapias de combinacion para el tratamiento de cancer que comprenden un derivado de bacterioclorofila.
MX2023001425A (es) Inhibidores de cinasa de insercion proviral en linfomas murinos (pim) para el tratamiento de neoplasias mieloproliferativas y fibrosis asociadas con cancer.
MX2016008027A (es) Uso de laquinimod para retrasar la evolucion de la enfermedad de huntington.
MX2022014792A (es) Cocristales, composiciones farmaceuticas de los mismos y metodos de tratamiento que los implican.
MX2021014523A (es) Metodos para tratar colangiocarcinoma.
MX2022000394A (es) Combinaciones terapeuticas de paclitaxel oralmente administrado y un inhibidor de la bomba de p-glicoproteina (p-gp) para el tratamiento del cancer.
MX2020008881A (es) Métodos de tratamiento contra el cáncer que comprenden inhibidores de chk1.
MX2023007826A (es) Metodos que comprenden una dosificacion intermitente fija de cediranib.
EA202191165A1 (ru) Элацестрант в комбинации с абемациклибом у женщин с раком молочной железы
MX2023015097A (es) Tratamiento de sintomas asociados a neoplasias mieloproliferativas.