MX2020012573A - Receptores del antigeno quimerico dirigidos al antigeno de maduracion de celulas b. - Google Patents

Receptores del antigeno quimerico dirigidos al antigeno de maduracion de celulas b.

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Publication number
MX2020012573A
MX2020012573A MX2020012573A MX2020012573A MX2020012573A MX 2020012573 A MX2020012573 A MX 2020012573A MX 2020012573 A MX2020012573 A MX 2020012573A MX 2020012573 A MX2020012573 A MX 2020012573A MX 2020012573 A MX2020012573 A MX 2020012573A
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Mexico
Prior art keywords
cars
cell maturation
antigen
immune cells
engineered immune
Prior art date
Application number
MX2020012573A
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English (en)
Inventor
Roman Galetto
Riggers Javier Fernando Chaparro
Blarcom Thomas John Van
Barbra Johnson Sasu
Arvind Rajpal
Alexandre Juillerat
Bijan Andre Boldajipour
Cesar Adolfo Sommer
Thomas Charles Pertel
Philippe Duchateau
Julien Valton
Tracy Chia Chien Kuo
Original Assignee
Pfizer
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Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX2020012573A publication Critical patent/MX2020012573A/es

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Abstract

La invención provee CARs (CARs) que específicamente unen a BCMA (antígeno de maduración de célula B). La invención además se refiere a células inmunes manipuladas que comprenden dichos CARs, ácidos nucleicos que codifican CAR, y métodos de hacer dichos CARs, células inmunes manipuladas, y ácidos nucleicos. La invención además se refiere a métodos terapéuticos para uso de estos CARs y células inmunes manipuladas para el tratamiento de una condición asociada con células malignas que expresan BCMA (por ejemplo, cáncer).
MX2020012573A 2015-04-13 2017-10-13 Receptores del antigeno quimerico dirigidos al antigeno de maduracion de celulas b. MX2020012573A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562146825P 2015-04-13 2015-04-13
US201662286473P 2016-01-25 2016-01-25
US201662301177P 2016-02-29 2016-02-29

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MX2020012573A true MX2020012573A (es) 2021-02-09

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JP6698546B2 (ja) 2014-04-14 2020-05-27 セレクティスＣｅｌｌｅｃｔｉｓ 癌免疫療法のためのｂｃｍａ（ｃｄ２６９）特異的キメラ抗原受容体
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