MX2020005458A - Variantes de alfa-amilasa y polinucleotidos que codifican las mismas. - Google Patents

Variantes de alfa-amilasa y polinucleotidos que codifican las mismas.

Info

Publication number
MX2020005458A
MX2020005458A MX2020005458A MX2020005458A MX2020005458A MX 2020005458 A MX2020005458 A MX 2020005458A MX 2020005458 A MX2020005458 A MX 2020005458A MX 2020005458 A MX2020005458 A MX 2020005458A MX 2020005458 A MX2020005458 A MX 2020005458A
Authority
MX
Mexico
Prior art keywords
seq
alpha
polynucleotides encoding
variants
amylase variants
Prior art date
Application number
MX2020005458A
Other languages
English (en)
Inventor
Carsten Andersen
Vivek Srivastava
Kendra Stallings
Vasudeva Prahlada Rao
Rakhi Saikia
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Publication of MX2020005458A publication Critical patent/MX2020005458A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01001—Alpha-amylase (3.2.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K1/00—Glucose; Glucose-containing syrups
    • C13K1/06—Glucose; Glucose-containing syrups obtained by saccharification of starch or raw materials containing starch
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se refiere a variantes de alfaamilasa que comprenden una sustitución en una posición correspondiente a la posición 188 y al menos una sustitución adicional en una posición correspondiente a la posición 242 o 279 o 275 de SEC. ID NO.: 1, en particular, una o más combinaciones de sustituciones seleccionadas del grupo que consiste en E188P+S242Y, E188P+S242F, E188P+S242H, E188P+S242W, E188P+S242P, E188P+S242I, E188P+S242T, E188P+S242L, E188P+K279W, E188P+K279Y, E188P+K279F, E188P+K279H, E188P+K279I, E188P+K279L, E188P+K279D, E188P+K279M, E188P+K279S, E188P+K279T E188P+K279N, E188P+K279Q, E188P+K279V, E188P+K279A, E188P+N275F, E188P+N275Y, E188P+N275W y E188P+N275H, donde la variante tiene al menos el 60 %, al menos el 65 %, al menos el 70 %, al menos el 75 %, al menos el 80 %, al menos el 85 %, al menos el 90 %, al menos el 95 %, al menos el 96 %, al menos el 97 %, al menos el 98 % o al menos el 99 %, pero menos del 100 % de identidad de secuencia con una alfa-amilasa precursora seleccionada del grupo que consiste en: SEC. ID NO.: 1, SEC. ID NO.: 2, SEC. ID NO.: 3, SEC. ID NO.: 4, SEC. ID NO.: 5, SEC. ID NO.: 6, SEC. ID NO.: 7, SEC. ID NO.: 8, SEC. ID NO.: 9, SEC. ID NO.: 10, SEC. ID NO.: 11, SEC. ID NO.: 12, SEC. ID NO.: 13, SEC. ID NO.: 14, SEC. ID NO.: 15, SEC. ID NO.: 16, SEC. ID NO.: 17, SEC. ID NO.: 18 y SEC. ID NO.: 27. La presente invención también se refiere a polinucleótidos que codifican las variantes; a construcciones de ácido nucleico, vectores y células hospedadoras que comprenden los polinucleótidos; y a métodos para usar las variantes.
MX2020005458A 2017-12-08 2018-12-07 Variantes de alfa-amilasa y polinucleotidos que codifican las mismas. MX2020005458A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN201741044156 2017-12-08
IN201841031044 2018-08-20
PCT/US2018/064413 WO2019113413A1 (en) 2017-12-08 2018-12-07 Alpha-amylase variants and polynucleotides encoding same

Publications (1)

Publication Number Publication Date
MX2020005458A true MX2020005458A (es) 2020-08-27

Family

ID=64746662

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020005458A MX2020005458A (es) 2017-12-08 2018-12-07 Variantes de alfa-amilasa y polinucleotidos que codifican las mismas.

Country Status (11)

Country Link
US (1) US11326153B2 (es)
EP (1) EP3720955B1 (es)
JP (2) JP2021505167A (es)
CN (1) CN111601887A (es)
BR (1) BR112020011278A2 (es)
DK (1) DK3720955T5 (es)
ES (1) ES2955269T3 (es)
FI (1) FI3720955T3 (es)
MX (1) MX2020005458A (es)
PY (1) PY18107830A (es)
WO (1) WO2019113413A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3942032A1 (en) * 2019-03-21 2022-01-26 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
CN113993996A (zh) * 2019-06-24 2022-01-28 诺维信公司 α-淀粉酶变体
CN114787329A (zh) * 2019-08-27 2022-07-22 诺维信公司 洗涤剂组合物
US20230399632A1 (en) * 2020-11-02 2023-12-14 Novozymes A/S Glucoamylase Variants and Polynucleotides Encoding Same
JP2024508766A (ja) * 2021-02-22 2024-02-28 ベーアーエスエフ・エスエー アミラーゼバリアント
JP2023095355A (ja) * 2021-12-24 2023-07-06 花王株式会社 アミラーゼ配合洗浄剤組成物
EP4495232A4 (en) * 2022-03-18 2026-02-25 Kao Corp VARIANT OF ALPHA-AMYLASE
CN114606216B (zh) * 2022-03-31 2023-08-11 山东隆科特酶制剂有限公司 一种表达量提高的α-淀粉酶突变体Q441N/N442H及其编码基因和应用
CA3257053A1 (en) 2022-05-14 2023-11-23 Novozymes A/S COMPOSITIONS AND METHODS FOR THE PREVENTION, TREATMENT, SUPPRESSION AND/OR ELIMINATION OF PHYTOPATHOGENIC INFESTATIONS AND INFECTIONS
WO2024137704A2 (en) 2022-12-19 2024-06-27 Novozymes A/S Processes for producing fermentation products using fiber-degrading enzymes with engineered yeast
CN120380140A (zh) 2022-12-19 2025-07-25 诺维信公司 具有阿魏酸酯酶和/或乙酰木聚糖酯酶活性的碳水化合物酯酶家族1（ce1）多肽和编码其的多核苷酸
WO2024137250A1 (en) 2022-12-19 2024-06-27 Novozymes A/S Carbohydrate esterase family 3 (ce3) polypeptides having acetyl xylan esterase activity and polynucleotides encoding same
CN120693401A (zh) 2022-12-19 2025-09-23 诺维信公司 包含阿拉伯呋喃糖苷酶和木聚糖酶的组合物及其用于增加半纤维素纤维溶解的用途
WO2024137252A1 (en) 2022-12-19 2024-06-27 Novozymes A/S Process for reducing syrup viscosity in the backend of a process for producing a fermentation product
CN116286763B (zh) * 2023-02-28 2024-06-25 西北工业大学 一种热稳定性提高的胱硫醚β-合成酶突变体及应用
MX2025015096A (es) 2023-06-13 2026-02-03 Novozymes As Procesos para producir productos de fermentacion usando levaduras modificadas que expresan una beta-xilosidasa
WO2025128568A1 (en) 2023-12-11 2025-06-19 Novozymes A/S Composition and use thereof for increasing hemicellulosic fiber solubilization
WO2026008449A2 (en) 2024-07-04 2026-01-08 Novozymes A/S A process for producing a fermentation product and a concentrated protein co-product

Family Cites Families (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3912590A (en) 1973-01-03 1975-10-14 Novo Industri As Procedure for liquefying starch
US4316956A (en) 1980-02-06 1982-02-23 Novo Industri A/S Fermentation process
US4335208A (en) 1980-03-11 1982-06-15 Novo Industri A/S Saccharification of starch hydrolysates
JPS57174089A (en) 1981-04-20 1982-10-26 Novo Industri As Chain dividing enzyme product
US4560651A (en) 1981-04-20 1985-12-24 Novo Industri A/S Debranching enzyme product, preparation and use thereof
GR76237B (es) 1981-08-08 1984-08-04 Procter & Gamble
DK166460B1 (da) 1986-07-09 1993-05-24 Novo Nordisk As Blandinger af alfa-amylaser og deres anvendelse til stivelsesforflydning
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
ES2094155T3 (es) 1989-06-13 1997-01-16 Genencor Int Procedimiento para la neutralizacion de celulas sin lisis celular.
GB8927361D0 (en) 1989-12-04 1990-01-31 Unilever Plc Liquid detergents
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
US5231017A (en) 1991-05-17 1993-07-27 Solvay Enzymes, Inc. Process for producing ethanol
CA2124787C (en) 1991-12-13 1998-10-27 Frederick E. Hardy Acylated citrate esters as peracid precursors
FR2704860B1 (fr) 1993-05-05 1995-07-13 Pasteur Institut Sequences de nucleotides du locus cryiiia pour le controle de l'expression de sequences d'adn dans un hote cellulaire.
US5360569A (en) 1993-11-12 1994-11-01 Lever Brothers Company, Division Of Conopco, Inc. Activation of bleach precursors with catalytic imine quaternary salts
US5360568A (en) 1993-11-12 1994-11-01 Lever Brothers Company, Division Of Conopco, Inc. Imine quaternary salts as bleach catalysts
DE4343591A1 (de) 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
KR970703426A (ko) 1994-06-03 1997-07-03 제임스 쉐한 정제된 Myceliophthora 락카제 및 그것을 암호화 하는 핵산(PURIFIED MYCELIOPHTHORA LACCASES AND NUCLEIC ACIDS ENCODING SAME)
US5534179A (en) 1995-02-03 1996-07-09 Procter & Gamble Detergent compositions comprising multiperacid-forming bleach activators
AR000862A1 (es) 1995-02-03 1997-08-06 Novozymes As Variantes de una ó-amilasa madre, un metodo para producir la misma, una estructura de adn y un vector de expresion, una celula transformada por dichaestructura de adn y vector, un aditivo para detergente, composicion detergente, una composicion para lavado de ropa y una composicion para la eliminacion del
US5597936A (en) 1995-06-16 1997-01-28 The Procter & Gamble Company Method for manufacturing cobalt catalysts
DE19528059A1 (de) 1995-07-31 1997-02-06 Bayer Ag Wasch- und Reinigungsmittel mit Iminodisuccinaten
US5576282A (en) 1995-09-11 1996-11-19 The Procter & Gamble Company Color-safe bleach boosters, compositions and laundry methods employing same
MA24137A1 (fr) 1996-04-16 1997-12-31 Procter & Gamble Fabrication d'agents de surface ramifies .
US5817614A (en) 1996-08-29 1998-10-06 Procter & Gamble Company Color-safe bleach boosters, compositions and laundry methods employing same
ATE256173T1 (de) 1996-10-18 2003-12-15 Procter & Gamble Waschmittelzusammensetzungen
US5753599A (en) 1996-12-03 1998-05-19 Lever Brothers Company, Division Of Conopco, Inc. Thiadiazole dioxides as bleach enhancers
CN1262632C (zh) 1997-03-07 2006-07-05 普罗格特-甘布尔公司 含有金属漂白催化剂和漂白活化剂和/或有机过羧酸的漂白组合物
AU6226198A (en) 1997-03-07 1998-09-22 Procter & Gamble Company, The Improved methods of making cross-bridged macropolycycles
US6218351B1 (en) 1998-03-06 2001-04-17 The Procter & Gamble Compnay Bleach compositions
TR199902673T2 (en) 1997-03-07 2000-04-21 The Procter & Gamble Company A�art�c� bile�imler.
JP3601835B2 (ja) 1997-06-10 2004-12-15 タカラバイオ株式会社 超耐熱性プロテアーゼ発現系
DK2206768T3 (en) 1997-10-13 2015-06-29 Novozymes As Alfa-amylasemutanter
US5955310A (en) 1998-02-26 1999-09-21 Novo Nordisk Biotech, Inc. Methods for producing a polypeptide in a bacillus cell
PH11999002190B1 (en) 1998-09-01 2007-08-06 Unilever Nv Composition and method for bleaching a substrate
EP1135392A2 (en) 1998-11-30 2001-09-26 The Procter & Gamble Company Process for preparing cross-bridged tetraaza macrocycles
CN1252256C (zh) 1999-03-30 2006-04-19 诺维信公司 α－淀粉酶变体
AU2663801A (en) 2000-01-12 2001-07-24 Novozymes A/S Pullulanase variants and methods for preparing such variants with predetermined properties
AU2002210380A1 (en) * 2000-10-13 2002-04-22 Novozymes A/S Alpha-amylase variant with altered properties
DE10058645A1 (de) 2000-11-25 2002-05-29 Clariant Gmbh Verwendung von cyclischen Zuckerketonen als Katalysatoren für Persauerstoffverbindungen
ATE375388T1 (de) 2001-07-27 2007-10-15 Us Gov Health & Human Serv Systeme zur stellengerichteten in-vivo-mutagenese mit oligonukleotiden
WO2003048353A1 (en) 2001-12-07 2003-06-12 Novozymes A/S Polypeptides having protease activity and nucleic acids encoding same
GB0325432D0 (en) 2003-10-31 2003-12-03 Unilever Plc Ligand and complex for catalytically bleaching a substrate
US20050113246A1 (en) 2003-11-06 2005-05-26 The Procter & Gamble Company Process of producing an organic catalyst
US7208459B2 (en) 2004-06-29 2007-04-24 The Procter & Gamble Company Laundry detergent compositions with efficient hueing dye
PL2009088T3 (pl) 2004-09-23 2010-07-30 Unilever Nv Kompozycje do obróbki praniem
DE102004047777B4 (de) * 2004-10-01 2018-05-09 Basf Se Alpha-Amylase-Varianten mit erhöhter Lösungsmittelstabilität, Verfahren zu deren Herstellung sowie deren Verwendung
JP5117403B2 (ja) 2006-01-23 2013-01-16 ザ プロクター アンド ギャンブル カンパニー 酵素および光漂白剤を含む組成物
AR059156A1 (es) 2006-01-23 2008-03-12 Procter & Gamble Composiciones detergentes
CA2635927A1 (en) 2006-01-23 2007-08-02 The Procter And Gamble Company A composition comprising a lipase and a bleach catalyst
JP2009523904A (ja) 2006-01-23 2009-06-25 ザ プロクター アンド ギャンブル カンパニー リパーゼと漂白剤触媒を含む組成物
ATE557080T1 (de) 2007-01-19 2012-05-15 Procter & Gamble Wäschepflegezusammensetzung mit bleichmittel für cellulosesubstrate
MX2009013494A (es) 2007-06-11 2010-01-18 Procter & Gamble Agente benefico que contiene particulas de suministro.
KR20100085964A (ko) 2007-11-05 2010-07-29 다니스코 유에스 인크. 변경된 특성을 가진 알파-아밀라아제 변이체
US20090209447A1 (en) 2008-02-15 2009-08-20 Michelle Meek Cleaning compositions
MX2010010468A (es) 2008-03-26 2010-10-20 Procter & Gamble Particula de suministro.
CN102057040A (zh) * 2008-06-06 2011-05-11 丹尼斯科美国公司 具有改良特性的嗜热脂肪土芽孢杆菌α-淀粉酶(AMYS)变体
EP2364363A2 (en) 2008-06-23 2011-09-14 Novozymes A/S Processes for producing fermentation products
DK2337837T4 (en) 2008-09-25 2017-02-06 Danisco Us Inc ALPHA-AMYLASE MIXTURES AND PROCEDURES FOR USING IT
MX2011008495A (es) 2009-02-20 2011-09-21 Danisco Us Inc Formulaciones de caldo de fermentacion.
BRPI1013388A2 (pt) 2009-04-01 2019-04-09 Danisco Us Inc composição de limpeza que compreende uma alfa-amilase e uma protease e método de limpeza de um tecido ou superficie dura
ES2534098T3 (es) 2009-11-30 2015-04-17 Novozymes A/S Polipéptidos que tienen actividad de glucoamilasa y polinucleótidos que codifican los mismos
CA2782036C (en) 2009-12-01 2019-01-15 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
MX2012007709A (es) * 2010-01-04 2012-08-15 Novozymes As Variantes de alfa-amilasa con estabilidad mejorada.
WO2011107472A1 (en) 2010-03-01 2011-09-09 Novozymes A/S Viscosity pressure assay
CA2795806C (en) 2010-04-14 2019-01-08 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
CN103298932B (zh) 2010-11-08 2016-08-10 诺维信公司 具有葡糖淀粉酶活性的多肽和编码该多肽的多核苷酸
CA2822637C (en) 2010-12-22 2020-06-30 Novozymes A/S Processes for producing fermentation products
CN103781910B (zh) 2011-07-06 2019-04-23 诺维信公司 α淀粉酶变体及其编码多核苷酸
CA2853000C (en) 2011-10-11 2022-03-15 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
MX354704B (es) 2011-10-17 2018-03-16 Novozymes As Variantes de alfa-amilasa y polinucleotidos que codifican las mismas.
MX355356B (es) * 2011-10-17 2018-04-17 Novozymes As Variantes de alfa-amilasa y polinucleotidos que codifican las mismas.
IN2014CN04905A (es) 2011-12-02 2015-09-18 Novozymes As
US20160160199A1 (en) * 2013-10-03 2016-06-09 Danisco Us Inc. Alpha-amylases from exiguobacterium, and methods of use, thereof
WO2017015329A1 (en) 2015-07-23 2017-01-26 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same

Also Published As

Publication number Publication date
BR112020011278A2 (pt) 2020-11-17
JP2024026072A (ja) 2024-02-28
WO2019113413A1 (en) 2019-06-13
CA3084211A1 (en) 2019-06-13
CN111601887A (zh) 2020-08-28
ES2955269T3 (es) 2023-11-29
PY18107830A (es) 2020-05-04
DK3720955T3 (da) 2023-09-04
EP3720955A1 (en) 2020-10-14
US11326153B2 (en) 2022-05-10
US20210189364A1 (en) 2021-06-24
FI3720955T3 (fi) 2023-09-05
EP3720955B1 (en) 2023-06-14
JP2021505167A (ja) 2021-02-18
DK3720955T5 (da) 2024-08-26

Similar Documents

Publication Publication Date Title
MX2020005458A (es) Variantes de alfa-amilasa y polinucleotidos que codifican las mismas.
MX2020005724A (es) Variantes de alfa-amilasa y polinucleotidos que codifican las mismas.
MX2020004149A (es) Variantes de desoxirribonucleasa (dnasa).
CO2017011957A2 (es) Variantes de alfa-amilasa y polinucleótidos que codifican las mismas
CO2018009120A2 (es) Genes del factor viii optimizados
CL2020002973A1 (es) Casetes de expresión de a- glucosidasa de ácido optimizado con codón y métodos de uso del mismo
MX2017007731A (es) Composiciones de detergente, variantes de lipasa y polinucleotidos que codifican las mismas.
MX2017016610A (es) Metodos de reduccion de olor.
MX2018000307A (es) Factor ix modificado, y composiciones, metodos y usos para la transferencia de genes a celulas, organos y tejidos.
AR100606A1 (es) Variantes de lipasas y polinucleótidos que las codifican
MX2017016688A (es) Nuevas enzimas y sistemas crispr.
MX2018008051A (es) Variantes de beta-glucanasa y polinucleotidos que las codifican.
PE20171382A1 (es) ARNi VARIANTE
MX2015015606A (es) Composiciones detergentes.
MX2017007105A (es) Variantes de lipasa y polinucleotidos que las codifican.
CL2019000033A1 (es) Variantes de xilanasa y polinucleótidos que las codifican.
MX2019000805A (es) Variantes de serinproteasa y polinucleotidos que las codifican.
MX2019008967A (es) Variantes de alfa-amilasas.
MX2019000743A (es) Variantes de serinproteasa y polinucleotidos que las codifican.
MX2021000322A (es) Enzimas de variante fosfopentomutasa modificada geneticamente.
MX2021013879A (es) Variantes de lipasa y polinucleotidos que las codifican.
EP3950939A3 (en) Lipase variants and polynucleotides encoding same
AR093923A1 (es) Polipeptidos con actividad fosfolipasa c y polinucleotidos que los codifican
AR101146A1 (es) Proteína con actividad xilanasa
MX382651B (es) Composiciones, organismos, sistemas y métodos para cítricos resistentes a patógenos