MX2019013756A - Vacunas contra el cancer y metodos de tratamiento que las utilizan. - Google Patents
Vacunas contra el cancer y metodos de tratamiento que las utilizan.Info
- Publication number
- MX2019013756A MX2019013756A MX2019013756A MX2019013756A MX2019013756A MX 2019013756 A MX2019013756 A MX 2019013756A MX 2019013756 A MX2019013756 A MX 2019013756A MX 2019013756 A MX2019013756 A MX 2019013756A MX 2019013756 A MX2019013756 A MX 2019013756A
- Authority
- MX
- Mexico
- Prior art keywords
- antigen
- cancer
- tyrosinase
- methods
- eso
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000009566 cancer vaccine Methods 0.000 title 1
- 229940022399 cancer vaccine Drugs 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 5
- 239000000427 antigen Substances 0.000 abstract 5
- 102000036639 antigens Human genes 0.000 abstract 5
- 108091007433 antigens Proteins 0.000 abstract 5
- 201000011510 cancer Diseases 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 3
- 229960005486 vaccine Drugs 0.000 abstract 3
- 102100030310 5,6-dihydroxyindole-2-carboxylic acid oxidase Human genes 0.000 abstract 2
- 101000655352 Homo sapiens Telomerase reverse transcriptase Proteins 0.000 abstract 2
- 102100031413 L-dopachrome tautomerase Human genes 0.000 abstract 2
- 102100037020 Melanoma antigen preferentially expressed in tumors Human genes 0.000 abstract 2
- 101710178381 Melanoma antigen preferentially expressed in tumors Proteins 0.000 abstract 2
- 102100028389 Melanoma antigen recognized by T-cells 1 Human genes 0.000 abstract 2
- 102100025077 Melanoma-associated antigen 4 Human genes 0.000 abstract 2
- 102000007066 Prostate-Specific Antigen Human genes 0.000 abstract 2
- 108010072866 Prostate-Specific Antigen Proteins 0.000 abstract 2
- 102000040856 WT1 Human genes 0.000 abstract 2
- 108700020467 WT1 Proteins 0.000 abstract 2
- 108010051081 dopachrome isomerase Proteins 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 210000001550 testis Anatomy 0.000 abstract 2
- 102100025570 Cancer/testis antigen 1 Human genes 0.000 abstract 1
- 108010051696 Growth Hormone Proteins 0.000 abstract 1
- 101000773083 Homo sapiens 5,6-dihydroxyindole-2-carboxylic acid oxidase Proteins 0.000 abstract 1
- 101000856237 Homo sapiens Cancer/testis antigen 1 Proteins 0.000 abstract 1
- 101000578784 Homo sapiens Melanoma antigen recognized by T-cells 1 Proteins 0.000 abstract 1
- 101001005720 Homo sapiens Melanoma-associated antigen 4 Proteins 0.000 abstract 1
- 108010010995 MART-1 Antigen Proteins 0.000 abstract 1
- 101710204291 Melanoma-associated antigen 4 Proteins 0.000 abstract 1
- 102100038803 Somatotropin Human genes 0.000 abstract 1
- 102000003425 Tyrosinase Human genes 0.000 abstract 1
- 108060008724 Tyrosinase Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical group 0.000 abstract 1
- 239000000122 growth hormone Substances 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 108010014402 tyrosinase-related protein-1 Proteins 0.000 abstract 1
Classifications
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Abstract
Se divulgan composiciones de vacuna que comprenden uno o más ácidos nucleicos que codifican una o más secuencias de aminoácidos seleccionadas del grupo que consiste en secuencias de aminoácidos de tirosinasa (Tyr), proteína 1 relacionada con tirosinasa (TYRP1), proteína 2 relacionada con tirosinasa (TYRP2), proteína de antígeno 4 asociada con melanoma (MAGEA4), hormona de liberación de hormona de crecimiento (GHRH), antígeno MART-1/melan-A, antígeno NY-ESO-1 de cáncer de testículo, antígeno NY-ESO-2 de cáncer de testículo, antígeno preferiblemente expresado en melanoma (PRAME), tumor de Wilms 1 (WT1) y transcriptasa reversa de telomerasa humana (hTERT); las composiciones de vacuna además pueden comprender un ácido nucleico que codifica uno o más de otros antígenos incluyendo antígeno específico de próstata (PSA); además se divulgan métodos para prevenir o tratar el cáncer en un sujeto que lo necesite que comprenden administrar al sujeto una composición de vacuna que comprende un número particular de antígenos de cáncer para tratar o prevenir un cáncer particular.
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US201361799952P | 2013-03-15 | 2013-03-15 |
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MX2015011486A MX369709B (es) | 2013-03-15 | 2014-03-14 | Vacunación mejorada contra tirosinasa. |
MX2019013756A MX2019013756A (es) | 2013-03-15 | 2015-09-02 | Vacunas contra el cancer y metodos de tratamiento que las utilizan. |
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MX2015011486A MX369709B (es) | 2013-03-15 | 2014-03-14 | Vacunación mejorada contra tirosinasa. |
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US (2) | US11419925B2 (es) |
EP (2) | EP3607974A1 (es) |
JP (4) | JP6769865B2 (es) |
KR (3) | KR20210123426A (es) |
CN (2) | CN114225019A (es) |
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CA (1) | CA2898126A1 (es) |
EA (2) | EA201992251A1 (es) |
HK (1) | HK1216991A1 (es) |
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WO (1) | WO2014144885A2 (es) |
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