MX2019011221A - Terapia de combinacion para el tratamiento o prevencion de tumores. - Google Patents
Terapia de combinacion para el tratamiento o prevencion de tumores.Info
- Publication number
- MX2019011221A MX2019011221A MX2019011221A MX2019011221A MX2019011221A MX 2019011221 A MX2019011221 A MX 2019011221A MX 2019011221 A MX2019011221 A MX 2019011221A MX 2019011221 A MX2019011221 A MX 2019011221A MX 2019011221 A MX2019011221 A MX 2019011221A
- Authority
- MX
- Mexico
- Prior art keywords
- tumours
- combination therapy
- prevention
- treatment
- treating
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 238000002648 combination therapy Methods 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title 1
- 229940076838 Immune checkpoint inhibitor Drugs 0.000 abstract 2
- 102000037984 Inhibitory immune checkpoint proteins Human genes 0.000 abstract 2
- 108091008026 Inhibitory immune checkpoint proteins Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000012274 immune-checkpoint protein inhibitor Substances 0.000 abstract 2
- 230000000981 bystander Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Abstract
La presente invención se refiere a una terapia de combinación para tumores que comprenden la administración de un compuesto de epoxitigliano y un inhibidor de punto de control inmunitario. En modalidades particulares, existe un método para tratar un tumor y/o tratar o prevenir uno o más tumores expectantes con la terapia. También se describen composiciones farmacéuticas y kits que contienen compuestos de epoxitigliano e inhibidores de punto de control inmunitarios.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2017901027A AU2017901027A0 (en) | 2017-03-23 | Combination Therapy | |
| PCT/AU2018/050277 WO2018170559A1 (en) | 2017-03-23 | 2018-03-23 | Combination therapy for the treatment or prevention of tumours |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019011221A true MX2019011221A (es) | 2019-11-01 |
Family
ID=63583892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019011221A MX2019011221A (es) | 2017-03-23 | 2018-03-23 | Terapia de combinacion para el tratamiento o prevencion de tumores. |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US11213506B2 (es) |
| EP (1) | EP3600281B1 (es) |
| JP (1) | JP6905075B2 (es) |
| KR (1) | KR102228055B1 (es) |
| CN (1) | CN110461324A (es) |
| AU (1) | AU2018238202B2 (es) |
| BR (1) | BR112019019748A2 (es) |
| CA (1) | CA3056685C (es) |
| DK (1) | DK3600281T3 (es) |
| EA (1) | EA201992220A1 (es) |
| ES (1) | ES2953575T3 (es) |
| FI (1) | FI3600281T3 (es) |
| HR (1) | HRP20230936T1 (es) |
| HU (1) | HUE063299T2 (es) |
| IL (1) | IL269522B1 (es) |
| LT (1) | LT3600281T (es) |
| MX (1) | MX2019011221A (es) |
| MY (1) | MY197427A (es) |
| NZ (1) | NZ756754A (es) |
| PH (1) | PH12019502132A1 (es) |
| PL (1) | PL3600281T3 (es) |
| PT (1) | PT3600281T (es) |
| RS (1) | RS64472B1 (es) |
| SG (1) | SG11201907891XA (es) |
| SI (1) | SI3600281T1 (es) |
| UA (1) | UA125614C2 (es) |
| WO (1) | WO2018170559A1 (es) |
| ZA (1) | ZA201906001B (es) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2391296T3 (es) * | 2005-12-23 | 2012-11-23 | Qbiotics Limited | Derivados de tiglien-3-ona |
| TWI721929B (zh) | 2013-08-05 | 2021-03-11 | 美商扭轉生物科技有限公司 | 重新合成之基因庫 |
| CA2975852A1 (en) | 2015-02-04 | 2016-08-11 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
| WO2016172377A1 (en) | 2015-04-21 | 2016-10-27 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
| IL258164B (en) | 2015-09-18 | 2022-09-01 | Twist Bioscience Corp | Methods to regulate the activity of proteins and cells and a method for the production of nucleic acids |
| WO2017053450A1 (en) | 2015-09-22 | 2017-03-30 | Twist Bioscience Corporation | Flexible substrates for nucleic acid synthesis |
| JP6871364B2 (ja) | 2016-09-21 | 2021-05-12 | ツイスト バイオサイエンス コーポレーション | 核酸に基づくデータ保存 |
| SG11201907713WA (en) | 2017-02-22 | 2019-09-27 | Twist Bioscience Corp | Nucleic acid based data storage |
| WO2018231864A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| CN111566209A (zh) | 2017-06-12 | 2020-08-21 | 特韦斯特生物科学公司 | 无缝核酸装配方法 |
| US11407837B2 (en) | 2017-09-11 | 2022-08-09 | Twist Bioscience Corporation | GPCR binding proteins and synthesis thereof |
| KR20240024357A (ko) | 2017-10-20 | 2024-02-23 | 트위스트 바이오사이언스 코포레이션 | 폴리뉴클레오타이드 합성을 위한 가열된 나노웰 |
| KR20210013128A (ko) | 2018-05-18 | 2021-02-03 | 트위스트 바이오사이언스 코포레이션 | 핵산 하이브리드화를 위한 폴리뉴클레오타이드, 시약 및 방법 |
| SG11202109283UA (en) | 2019-02-26 | 2021-09-29 | Twist Bioscience Corp | Variant nucleic acid libraries for antibody optimization |
| CN113924091A (zh) | 2019-04-12 | 2022-01-11 | Q生物股份有限公司 | 治疗肿瘤的方法 |
| AU2020297184A1 (en) * | 2019-06-19 | 2022-01-27 | QBiotics Pty Ltd | Biofilm disruption |
| EP3987019A4 (en) | 2019-06-21 | 2023-04-19 | Twist Bioscience Corporation | BARCODE-BASED NUCLEIC ACID SEQUENCE ARRANGEMENT |
| CA3164146A1 (en) * | 2019-12-09 | 2021-06-17 | Twist Bioscience Corporation | Variant nucleic acid libraries for adenosine receptors |
| KR20220151333A (ko) | 2021-05-06 | 2022-11-15 | 한국과학기술연구원 | 가시광선에 의해 활성화되는 항암 면역치료용 나노입자 및 이의 용도 |
| WO2023115123A1 (en) * | 2021-12-21 | 2023-06-29 | QBiotics Pty Ltd | Crystalline intermediates |
| WO2023154984A1 (en) * | 2022-02-17 | 2023-08-24 | QBiotics Pty Ltd | Combination therapies |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007009055A2 (en) * | 2005-07-13 | 2007-01-18 | Salvia Sciences, Inc. | Ester prodrugs of prostratin and related phorbol compounds |
| ES2391296T3 (es) * | 2005-12-23 | 2012-11-23 | Qbiotics Limited | Derivados de tiglien-3-ona |
| EA032501B9 (ru) | 2013-04-18 | 2019-11-29 | Qbiotics Ltd | Способы и композиции для содействия заживлению острой раны и хронической раны |
| WO2015133596A1 (ja) * | 2014-03-07 | 2015-09-11 | 国立大学法人京都大学 | 細胞培養用組成物 |
| JP6843736B2 (ja) | 2014-07-16 | 2021-03-17 | トランジェーヌＴｒａｎｓｇｅｎｅ | 腫瘍溶解性ウイルスと免疫チェックポイントモジュレーターとの組合せ |
| KR20170072244A (ko) | 2014-10-10 | 2017-06-26 | 이데라 파마슈티칼즈, 인코포레이티드 | 관문 억제제를 가지는 tlr9 효능제를 이용한 암 치료 |
| CN104926758A (zh) * | 2015-05-22 | 2015-09-23 | 南京泽朗医药科技有限公司 | 斑籽素的制备方法及其在抗白血病药物中的应用 |
| EP3331851A1 (en) * | 2015-08-03 | 2018-06-13 | Quadriga Biosciences, Inc. | Beta-substituted beta-amino acids and analogs as chemotherapeutic agents and uses thereof |
-
2018
- 2018-03-23 BR BR112019019748A patent/BR112019019748A2/pt active Search and Examination
- 2018-03-23 JP JP2019552088A patent/JP6905075B2/ja active Active
- 2018-03-23 EA EA201992220A patent/EA201992220A1/ru unknown
- 2018-03-23 US US16/496,333 patent/US11213506B2/en active Active
- 2018-03-23 HR HRP20230936TT patent/HRP20230936T1/hr unknown
- 2018-03-23 CN CN201880019617.4A patent/CN110461324A/zh active Pending
- 2018-03-23 FI FIEP18770812.8T patent/FI3600281T3/fi active
- 2018-03-23 MX MX2019011221A patent/MX2019011221A/es unknown
- 2018-03-23 ES ES18770812T patent/ES2953575T3/es active Active
- 2018-03-23 RS RS20230697A patent/RS64472B1/sr unknown
- 2018-03-23 AU AU2018238202A patent/AU2018238202B2/en active Active
- 2018-03-23 UA UAA201910449A patent/UA125614C2/uk unknown
- 2018-03-23 KR KR1020197031149A patent/KR102228055B1/ko active IP Right Grant
- 2018-03-23 PT PT187708128T patent/PT3600281T/pt unknown
- 2018-03-23 IL IL269522A patent/IL269522B1/en unknown
- 2018-03-23 PL PL18770812.8T patent/PL3600281T3/pl unknown
- 2018-03-23 SG SG11201907891XA patent/SG11201907891XA/en unknown
- 2018-03-23 SI SI201830978T patent/SI3600281T1/sl unknown
- 2018-03-23 NZ NZ756754A patent/NZ756754A/en unknown
- 2018-03-23 DK DK18770812.8T patent/DK3600281T3/da active
- 2018-03-23 EP EP18770812.8A patent/EP3600281B1/en active Active
- 2018-03-23 MY MYPI2019005163A patent/MY197427A/en unknown
- 2018-03-23 CA CA3056685A patent/CA3056685C/en active Active
- 2018-03-23 HU HUE18770812A patent/HUE063299T2/hu unknown
- 2018-03-23 WO PCT/AU2018/050277 patent/WO2018170559A1/en active Application Filing
- 2018-03-23 LT LTEPPCT/AU2018/050277T patent/LT3600281T/lt unknown
-
2019
- 2019-09-11 ZA ZA2019/06001A patent/ZA201906001B/en unknown
- 2019-09-17 PH PH12019502132A patent/PH12019502132A1/en unknown
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