MX2019005999A - Precipitacion de la fraccion i-iv-1 de inmunoglobulinas plasmaticas. - Google Patents
Precipitacion de la fraccion i-iv-1 de inmunoglobulinas plasmaticas.Info
- Publication number
- MX2019005999A MX2019005999A MX2019005999A MX2019005999A MX2019005999A MX 2019005999 A MX2019005999 A MX 2019005999A MX 2019005999 A MX2019005999 A MX 2019005999A MX 2019005999 A MX2019005999 A MX 2019005999A MX 2019005999 A MX2019005999 A MX 2019005999A
- Authority
- MX
- Mexico
- Prior art keywords
- plasma
- provides
- immunoglobins
- precipitation
- fraction
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/145—Extraction; Separation; Purification by extraction or solubilisation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Developmental Biology & Embryology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Métodos para elaborar composiciones de proteínas sanguíneas a partir de plasma agrupado. En una modalidad, se provee un esquema de fraccionamiento con alcohol que permite aumentar significativamente el rendimiento de proteínas sanguíneas purificadas a partir de una muestra de plasma de partida. En una modalidad específica se provee un método de fraccionamiento de plasma agrupado que comprende un paso inicial de precipitación con una concentración elevada de alcohol, a pH bajo. También se proveen composiciones farmacéuticas con proteínas sanguíneas terapéuticas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261602488P | 2012-02-23 | 2012-02-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019005999A true MX2019005999A (es) | 2019-08-21 |
Family
ID=47833446
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014010076A MX365236B (es) | 2012-02-23 | 2013-02-25 | Precipitacion de la fraccion i-iv-1 de inmunoglobulinas plasmaticas. |
| MX2019005999A MX2019005999A (es) | 2012-02-23 | 2014-08-21 | Precipitacion de la fraccion i-iv-1 de inmunoglobulinas plasmaticas. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014010076A MX365236B (es) | 2012-02-23 | 2013-02-25 | Precipitacion de la fraccion i-iv-1 de inmunoglobulinas plasmaticas. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US9782477B2 (es) |
| EP (2) | EP2817334B1 (es) |
| JP (1) | JP6291423B2 (es) |
| KR (1) | KR101930582B1 (es) |
| CN (1) | CN104245730B (es) |
| AR (1) | AR090425A1 (es) |
| AU (1) | AU2013203112B2 (es) |
| BR (1) | BR112014020602B1 (es) |
| CA (1) | CA2864715A1 (es) |
| CL (1) | CL2014002225A1 (es) |
| CO (1) | CO7081143A2 (es) |
| DK (1) | DK2817334T3 (es) |
| EA (1) | EA032478B1 (es) |
| ES (1) | ES2928954T3 (es) |
| HK (1) | HK1205520A1 (es) |
| HU (1) | HUE060195T2 (es) |
| IL (1) | IL234103B (es) |
| MX (2) | MX365236B (es) |
| MY (1) | MY167235A (es) |
| NZ (1) | NZ628529A (es) |
| PL (1) | PL2817334T3 (es) |
| PT (1) | PT2817334T (es) |
| SG (1) | SG11201405149UA (es) |
| SI (1) | SI2817334T1 (es) |
| TW (1) | TWI629283B (es) |
| WO (1) | WO2013126904A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013203043B2 (en) | 2013-03-15 | 2016-10-06 | Takeda Pharmaceutical Company Limited | Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs |
| CN104004091B (zh) * | 2014-06-12 | 2016-08-17 | 新疆德源生物工程有限公司 | 一种人免疫球蛋白的制备工艺 |
| CN104004090A (zh) * | 2014-06-12 | 2014-08-27 | 新疆德源生物工程有限公司 | 一种人免疫球蛋白的制备方法 |
| GB201413227D0 (en) | 2014-07-25 | 2014-09-10 | Bioproducts Lab Ltd | Process |
| ES2887588T3 (es) * | 2015-08-13 | 2021-12-23 | Kamada Ltd | Composiciones derivadas de pasta de fracción de Cohn y uso de las mismas |
| CN108163898B (zh) * | 2018-01-23 | 2020-12-04 | 中国科学院上海高等研究院 | 一种自调节铁氧体材料及其制备方法和应用 |
| AU2021355325A1 (en) * | 2020-04-10 | 2022-11-03 | Plasma Technologies, Llc | Compositions and methods for simplified high efficiency isolation of proteins |
| CN116322920A (zh) * | 2020-11-09 | 2023-06-23 | 武田药品工业株式会社 | 使用氧化硅吸附从血浆中纯化fviii |
| CN112250757A (zh) * | 2020-11-13 | 2021-01-22 | 广东深蓝生物科技有限公司 | 一种猪血浆中蛋白质的提取纯化方法 |
| JP2024501025A (ja) * | 2020-12-28 | 2024-01-10 | プラズマ テクノロジーズ エルエルシー | 免疫グロブリンｇのプロセススケールでの単離のためのシステム及び方法 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE348942B (es) | 1970-06-02 | 1972-09-18 | Statens Bakteriologiska Labor | |
| US3998946A (en) | 1975-04-23 | 1976-12-21 | The Regents Of The University Of Minnesota | Fibrinogen-free plasminogen-plasmin-free plasma and method of preparing and using same |
| US4136094A (en) | 1977-08-31 | 1979-01-23 | The Regents Of The University Of Minnesota | Preparation of intravenous human and animal gamma globulins and isolation of albumin |
| US4499073A (en) | 1981-08-24 | 1985-02-12 | Cutter Laboratories, Inc. | Intravenously injectable immune serum globulin |
| JPS5855432A (ja) * | 1981-09-29 | 1983-04-01 | Fujirebio Inc | 静脈注射用免疫グロブリンの製法 |
| DK166763C (da) | 1983-03-16 | 1993-07-12 | Immuno Ag | Immunoglobulin-g-holdig fraktion |
| US5177194A (en) | 1990-02-01 | 1993-01-05 | Baxter International, Inc. | Process for purifying immune serum globulins |
| FR2706466B1 (fr) | 1993-06-14 | 1995-08-25 | Aetsrn | Concentré d'immunoglobulines G à usage thérapeutique et procédé de production dudit concentré. |
| US6284874B1 (en) | 1994-06-17 | 2001-09-04 | Alpha Therapeutic Corporation | Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste |
| US5616693A (en) | 1996-07-01 | 1997-04-01 | Alpha Therapeutic Corporation | Process for seperating alpha-1-proteinase inhibitor from COHN IV1 +1V4 paste |
| TW491855B (en) | 1996-08-07 | 2002-06-21 | Csl Ltd | Purification of immunoglobulins |
| CA2232420A1 (en) | 1997-03-19 | 1998-09-19 | The Green Cross Corporation | Immunoglobulin preparation and preparation process thereof |
| GB9705810D0 (en) * | 1997-03-20 | 1997-05-07 | Common Services Agency | Intravenous immune globulin |
| US5886154A (en) | 1997-06-20 | 1999-03-23 | Lebing; Wytold R. | Chromatographic method for high yield purification and viral inactivation of antibodies |
| US6159471A (en) | 1997-10-23 | 2000-12-12 | Yoshitomi Pharmaceutical Industries, Ltd. | Room temperature storable immunoglobulin preparation for intravenous injection |
| SE0001128D0 (sv) | 2000-03-30 | 2000-03-30 | Amersham Pharm Biotech Ab | A method of producing IgG |
| FR2824568B1 (fr) | 2001-05-11 | 2004-04-09 | Lab Francais Du Fractionnement | Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique |
| EP1413860A4 (en) * | 2001-07-05 | 2009-02-25 | Hamamatsu Photonics Kk | SPECTROSCOPIC DEVICE |
| US6893639B2 (en) * | 2001-10-19 | 2005-05-17 | Hemacare Corporation | Method for high yield purification of immune globulins from blood plasma and blood plasma intermediates |
| SI1664123T2 (sl) | 2003-09-22 | 2012-03-30 | Kamada Ltd | Priprava inhibitorja alfa proteinaze v velikem merilu in njegova uporaba |
| BRPI0507298A (pt) | 2004-01-30 | 2007-07-03 | Suomen Punainen Risti Veripalv | processo para a produção de imunoglobulina segura a vìrus |
| KR101206788B1 (ko) | 2004-02-27 | 2012-11-30 | 옥타파르마 아게 | 정제된, 바이러스 안전한 항체 제제를 제공하는 방법 |
| US7807435B2 (en) | 2005-08-11 | 2010-10-05 | Baxter International Inc. | Method for the purification of alpha-1 proteinase inhibitor (a1PI) |
| WO2008113589A1 (en) | 2007-03-20 | 2008-09-25 | Csl Behring Gmbh | Methods for industrial scale production of therapeutic complement factor h preparations from human plasma |
| EP3708581A3 (en) | 2009-05-27 | 2021-10-20 | Takeda Pharmaceutical Company Limited | A method to produce a highly concentrated immunoglobulin preparation for subcutaneous use |
| AT516600B1 (de) * | 2009-07-23 | 2016-07-15 | Baxter Int | Herstellung von faktor h (fh) und fh-derivaten aus plasma |
| US8772462B2 (en) | 2010-05-26 | 2014-07-08 | Baxter International Inc. | Removal of serine proteases by treatment with finely divided silicon dioxide |
| AU2010202125B1 (en) * | 2010-05-26 | 2010-09-02 | Takeda Pharmaceutical Company Limited | A method to produce an immunoglobulin preparation with improved yield |
| JP5830096B2 (ja) | 2010-07-23 | 2015-12-09 | バクスター、インターナショナル、インコーポレイテッド | 血漿由来インターα阻害タンパク質（ＩａＩｐ）の製造方法 |
-
2013
- 2013-02-23 TW TW102106384A patent/TWI629283B/zh active
- 2013-02-25 PL PL13708051.1T patent/PL2817334T3/pl unknown
- 2013-02-25 ES ES13708051T patent/ES2928954T3/es active Active
- 2013-02-25 DK DK13708051.1T patent/DK2817334T3/da active
- 2013-02-25 BR BR112014020602-3A patent/BR112014020602B1/pt active IP Right Grant
- 2013-02-25 AU AU2013203112A patent/AU2013203112B2/en active Active
- 2013-02-25 US US13/776,448 patent/US9782477B2/en active Active
- 2013-02-25 HU HUE13708051A patent/HUE060195T2/hu unknown
- 2013-02-25 PT PT137080511T patent/PT2817334T/pt unknown
- 2013-02-25 AR ARP130100566A patent/AR090425A1/es not_active Application Discontinuation
- 2013-02-25 EP EP13708051.1A patent/EP2817334B1/en active Active
- 2013-02-25 SI SI201332012T patent/SI2817334T1/sl unknown
- 2013-02-25 MY MYPI2014002439A patent/MY167235A/en unknown
- 2013-02-25 NZ NZ628529A patent/NZ628529A/en unknown
- 2013-02-25 WO PCT/US2013/027681 patent/WO2013126904A1/en active Application Filing
- 2013-02-25 SG SG11201405149UA patent/SG11201405149UA/en unknown
- 2013-02-25 CN CN201380020621.XA patent/CN104245730B/zh active Active
- 2013-02-25 EP EP22191464.1A patent/EP4119574A1/en active Pending
- 2013-02-25 JP JP2014558931A patent/JP6291423B2/ja active Active
- 2013-02-25 EA EA201491564A patent/EA032478B1/ru not_active IP Right Cessation
- 2013-02-25 KR KR1020147026210A patent/KR101930582B1/ko active IP Right Grant
- 2013-02-25 MX MX2014010076A patent/MX365236B/es active IP Right Grant
- 2013-02-25 CA CA2864715A patent/CA2864715A1/en not_active Abandoned
-
2014
- 2014-08-13 IL IL23410314A patent/IL234103B/en active IP Right Grant
- 2014-08-21 MX MX2019005999A patent/MX2019005999A/es unknown
- 2014-08-21 CL CL2014002225A patent/CL2014002225A1/es unknown
- 2014-09-23 CO CO14210313A patent/CO7081143A2/es unknown
-
2015
- 2015-06-25 HK HK15106034.8A patent/HK1205520A1/xx unknown
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