DK2817334T3 - Fraktion i-iv-1 præcipitation af immunoglobiner fra plasma - Google Patents

Fraktion i-iv-1 præcipitation af immunoglobiner fra plasma Download PDF

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Publication number
DK2817334T3
DK2817334T3 DK13708051.1T DK13708051T DK2817334T3 DK 2817334 T3 DK2817334 T3 DK 2817334T3 DK 13708051 T DK13708051 T DK 13708051T DK 2817334 T3 DK2817334 T3 DK 2817334T3
Authority
DK
Denmark
Prior art keywords
immunoglobins
precipitation
fraction
plasma
Prior art date
Application number
DK13708051.1T
Other languages
English (en)
Inventor
Leopold Bruckschwaiger
Thomas Gundinger
Julia Nuernberger
Wolfgang Teschner
Hans-Peter Schwarz
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47833446&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2817334(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Application granted granted Critical
Publication of DK2817334T3 publication Critical patent/DK2817334T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/30Extraction; Separation; Purification by precipitation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/145Extraction; Separation; Purification by extraction or solubilisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK13708051.1T 2012-02-23 2013-02-25 Fraktion i-iv-1 præcipitation af immunoglobiner fra plasma DK2817334T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261602488P 2012-02-23 2012-02-23
PCT/US2013/027681 WO2013126904A1 (en) 2012-02-23 2013-02-25 Fraction i-iv-1 precipitation of immunoglobins from plasma

Publications (1)

Publication Number Publication Date
DK2817334T3 true DK2817334T3 (da) 2022-10-03

Family

ID=47833446

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13708051.1T DK2817334T3 (da) 2012-02-23 2013-02-25 Fraktion i-iv-1 præcipitation af immunoglobiner fra plasma

Country Status (26)

Country Link
US (1) US9782477B2 (da)
EP (2) EP4119574A1 (da)
JP (1) JP6291423B2 (da)
KR (1) KR101930582B1 (da)
CN (1) CN104245730B (da)
AR (1) AR090425A1 (da)
AU (1) AU2013203112B2 (da)
BR (1) BR112014020602B1 (da)
CA (1) CA2864715A1 (da)
CL (1) CL2014002225A1 (da)
CO (1) CO7081143A2 (da)
DK (1) DK2817334T3 (da)
EA (1) EA032478B1 (da)
ES (1) ES2928954T3 (da)
HK (1) HK1205520A1 (da)
HU (1) HUE060195T2 (da)
IL (1) IL234103B (da)
MX (2) MX365236B (da)
MY (1) MY167235A (da)
NZ (1) NZ628529A (da)
PL (1) PL2817334T3 (da)
PT (1) PT2817334T (da)
SG (1) SG11201405149UA (da)
SI (1) SI2817334T1 (da)
TW (1) TWI629283B (da)
WO (1) WO2013126904A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013203043B2 (en) 2013-03-15 2016-10-06 Takeda Pharmaceutical Company Limited Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs
CN104004090A (zh) * 2014-06-12 2014-08-27 新疆德源生物工程有限公司 一种人免疫球蛋白的制备方法
CN104004091B (zh) * 2014-06-12 2016-08-17 新疆德源生物工程有限公司 一种人免疫球蛋白的制备工艺
GB201413227D0 (en) 2014-07-25 2014-09-10 Bioproducts Lab Ltd Process
ES2887588T3 (es) * 2015-08-13 2021-12-23 Kamada Ltd Composiciones derivadas de pasta de fracción de Cohn y uso de las mismas
CN108163898B (zh) * 2018-01-23 2020-12-04 中国科学院上海高等研究院 一种自调节铁氧体材料及其制备方法和应用
AU2021355325A1 (en) * 2020-04-10 2022-11-03 Plasma Technologies, Llc Compositions and methods for simplified high efficiency isolation of proteins
CN116322920A (zh) * 2020-11-09 2023-06-23 武田药品工业株式会社 使用氧化硅吸附从血浆中纯化fviii
CN112250757A (zh) * 2020-11-13 2021-01-22 广东深蓝生物科技有限公司 一种猪血浆中蛋白质的提取纯化方法
WO2022146856A1 (en) * 2020-12-28 2022-07-07 Plasma Technologies, Llc Systems and Methods for Process Scale Isolation of Immunoglobulin G

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE348942B (da) 1970-06-02 1972-09-18 Statens Bakteriologiska Labor
US3998946A (en) 1975-04-23 1976-12-21 The Regents Of The University Of Minnesota Fibrinogen-free plasminogen-plasmin-free plasma and method of preparing and using same
US4136094A (en) 1977-08-31 1979-01-23 The Regents Of The University Of Minnesota Preparation of intravenous human and animal gamma globulins and isolation of albumin
US4499073A (en) 1981-08-24 1985-02-12 Cutter Laboratories, Inc. Intravenously injectable immune serum globulin
JPS5855432A (ja) * 1981-09-29 1983-04-01 Fujirebio Inc 静脈注射用免疫グロブリンの製法
DK166763C (da) 1983-03-16 1993-07-12 Immuno Ag Immunoglobulin-g-holdig fraktion
US5177194A (en) 1990-02-01 1993-01-05 Baxter International, Inc. Process for purifying immune serum globulins
FR2706466B1 (fr) 1993-06-14 1995-08-25 Aetsrn Concentré d'immunoglobulines G à usage thérapeutique et procédé de production dudit concentré.
US6284874B1 (en) 1994-06-17 2001-09-04 Alpha Therapeutic Corporation Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste
US5616693A (en) 1996-07-01 1997-04-01 Alpha Therapeutic Corporation Process for seperating alpha-1-proteinase inhibitor from COHN IV1 +1V4 paste
TW491855B (en) 1996-08-07 2002-06-21 Csl Ltd Purification of immunoglobulins
TW541179B (en) 1997-03-19 2003-07-11 Green Cross Corp Process for preparing immunoglobulin preparation
GB9705810D0 (en) * 1997-03-20 1997-05-07 Common Services Agency Intravenous immune globulin
US5886154A (en) 1997-06-20 1999-03-23 Lebing; Wytold R. Chromatographic method for high yield purification and viral inactivation of antibodies
PT911037E (pt) 1997-10-23 2002-12-31 Mitsubishi Pharma Corp Preparacao de imunoglobulina armazenavel a temperatura ambiente para injeccao intravenosa
SE0001128D0 (sv) 2000-03-30 2000-03-30 Amersham Pharm Biotech Ab A method of producing IgG
FR2824568B1 (fr) 2001-05-11 2004-04-09 Lab Francais Du Fractionnement Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique
JPWO2003004982A1 (ja) * 2001-07-05 2004-10-28 浜松ホトニクス株式会社 分光装置
US6893639B2 (en) * 2001-10-19 2005-05-17 Hemacare Corporation Method for high yield purification of immune globulins from blood plasma and blood plasma intermediates
ES2305845T5 (es) 2003-09-22 2012-04-12 Kamada Ltd. Preparación a gran escala de un inhibidor de proteinasa alfa-1 y su utilización
KR20070009995A (ko) 2004-01-30 2007-01-19 수오멘 푸나이넨 리스티 베리팔베루 바이러스 안전성 면역글로불린을 제조하는 방법
DK1718675T3 (da) 2004-02-27 2013-07-15 Octapharma Ag Fremgangsmåde til at tilvejebringe en oprenset virussikker antistoftilberedning
US7807435B2 (en) 2005-08-11 2010-10-05 Baxter International Inc. Method for the purification of alpha-1 proteinase inhibitor (a1PI)
ES2595059T3 (es) 2007-03-20 2016-12-27 Csl Behring Gmbh Métodos para la producción a escala industrial de preparados terapéuticos del Factor H del complemento a partir de plasma humano
TWI445714B (zh) * 2009-05-27 2014-07-21 Baxter Int 產製用於皮下使用之高濃度免疫球蛋白製備物之方法
US8304524B2 (en) * 2009-07-23 2012-11-06 Baxter International Inc. Manufacture of factor H (FH) and FH-derivatives from plasma
AU2010202125B1 (en) * 2010-05-26 2010-09-02 Takeda Pharmaceutical Company Limited A method to produce an immunoglobulin preparation with improved yield
US8772462B2 (en) 2010-05-26 2014-07-08 Baxter International Inc. Removal of serine proteases by treatment with finely divided silicon dioxide
EA201390156A1 (ru) 2010-07-23 2014-01-30 Бакстер Интернэшнл Инк. ПРОИЗВОДСТВО ИНТЕР-АЛЬФА-ИНГИБИТОРНЫХ БЕЛКОВ (IaIp) ИЗ ПЛАЗМЫ

Also Published As

Publication number Publication date
SG11201405149UA (en) 2014-09-26
BR112014020602A2 (pt) 2018-09-11
EP2817334B1 (en) 2022-09-21
AR090425A1 (es) 2014-11-12
EA201491564A1 (ru) 2015-04-30
EP2817334A1 (en) 2014-12-31
US20130224183A1 (en) 2013-08-29
HUE060195T2 (hu) 2023-02-28
AU2013203112A1 (en) 2013-09-12
WO2013126904A1 (en) 2013-08-29
IL234103B (en) 2019-11-28
PT2817334T (pt) 2022-10-17
SI2817334T1 (sl) 2022-11-30
MY167235A (en) 2018-08-14
EA032478B1 (ru) 2019-06-28
MX365236B (es) 2019-05-28
KR101930582B1 (ko) 2018-12-18
CO7081143A2 (es) 2014-10-10
KR20140135996A (ko) 2014-11-27
CN104245730A (zh) 2014-12-24
US9782477B2 (en) 2017-10-10
CN104245730B (zh) 2017-09-01
IL234103A0 (en) 2014-09-30
NZ628529A (en) 2016-09-30
JP6291423B2 (ja) 2018-03-14
TWI629283B (zh) 2018-07-11
ES2928954T3 (es) 2022-11-23
MX2019005999A (es) 2019-08-21
MX2014010076A (es) 2014-09-22
CL2014002225A1 (es) 2015-01-16
EP4119574A1 (en) 2023-01-18
CA2864715A1 (en) 2013-08-29
JP2015509506A (ja) 2015-03-30
PL2817334T3 (pl) 2022-11-21
BR112014020602B1 (pt) 2022-12-20
TW201348248A (zh) 2013-12-01
AU2013203112B2 (en) 2016-03-10
HK1205520A1 (en) 2015-12-18

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