MX2018006005A - Formulaciones que comprenden sales de oxalato de teneligliptin y solvatos de este. - Google Patents
Formulaciones que comprenden sales de oxalato de teneligliptin y solvatos de este.Info
- Publication number
- MX2018006005A MX2018006005A MX2018006005A MX2018006005A MX2018006005A MX 2018006005 A MX2018006005 A MX 2018006005A MX 2018006005 A MX2018006005 A MX 2018006005A MX 2018006005 A MX2018006005 A MX 2018006005A MX 2018006005 A MX2018006005 A MX 2018006005A
- Authority
- MX
- Mexico
- Prior art keywords
- teneligliptin
- solvates
- formulations
- oxalate salts
- pharmaceutically acceptable
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 150000003891 oxalate salts Chemical class 0.000 title abstract 2
- 239000012453 solvate Chemical class 0.000 title abstract 2
- WGRQANOPCQRCME-PMACEKPBSA-N teneligliptin Chemical class O=C([C@H]1NC[C@H](C1)N1CCN(CC1)C1=CC(=NN1C=1C=CC=CC=1)C)N1CCSC1 WGRQANOPCQRCME-PMACEKPBSA-N 0.000 title abstract 2
- 229950000034 teneligliptin Drugs 0.000 title abstract 2
- 229940123208 Biguanide Drugs 0.000 abstract 1
- 150000004283 biguanides Chemical class 0.000 abstract 1
- 208000018914 glucose metabolism disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN201721004095 | 2017-02-03 | ||
PCT/IB2018/050662 WO2018142334A1 (en) | 2017-02-03 | 2018-02-02 | Formulations comprising oxalate salts of teneligliptin and solvates thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018006005A true MX2018006005A (es) | 2019-05-16 |
Family
ID=63039388
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018006005A MX2018006005A (es) | 2017-02-03 | 2018-02-02 | Formulaciones que comprenden sales de oxalato de teneligliptin y solvatos de este. |
MX2018006006A MX2018006006A (es) | 2017-02-03 | 2018-02-02 | Sales de oxalato de teneligliptin y solvatos de este, intermediarios, proceso de preparacion y marcadores de estos. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018006006A MX2018006006A (es) | 2017-02-03 | 2018-02-02 | Sales de oxalato de teneligliptin y solvatos de este, intermediarios, proceso de preparacion y marcadores de estos. |
Country Status (10)
Country | Link |
---|---|
JP (2) | JP2019508385A (zh) |
KR (2) | KR20180100554A (zh) |
CN (2) | CN108884089A (zh) |
AU (2) | AU2018202623A1 (zh) |
BR (2) | BR112018010748A2 (zh) |
EA (1) | EA039402B1 (zh) |
MX (2) | MX2018006005A (zh) |
RU (2) | RU2018120216A (zh) |
TW (2) | TW201831473A (zh) |
WO (2) | WO2018142334A1 (zh) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPWO2020209350A1 (zh) * | 2019-04-12 | 2020-10-15 | ||
CN110028496A (zh) * | 2019-04-26 | 2019-07-19 | 梯尔希(南京)药物研发有限公司 | 一种特力利汀相关杂质的合成方法 |
WO2021053564A1 (en) * | 2019-09-17 | 2021-03-25 | Glenmark Pharmaceuticals Limited | Pharmaceutical composition comprising remogliflozin or salt or ester thereof and teneligliptin or salt thereof |
KR20210121421A (ko) | 2020-03-30 | 2021-10-08 | 코오롱생명과학 주식회사 | 테네리글리프틴 2.5브롬화수소산염 무정형의 제조방법 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI319322B (en) * | 2003-11-13 | 2010-01-11 | Ono Pharmaceutical Co | Frozen-dried preperation containing prostaglandin |
AU2006215041B2 (en) * | 2005-02-18 | 2012-05-31 | Mitsubishi Tanabe Pharma Corporation | Salt of proline derivative, solvate thereof, and production method thereof |
JP2012517977A (ja) * | 2009-02-13 | 2012-08-09 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Dpp−4阻害剤(リナグリプチン)を任意で他の抗糖尿病薬と組み合わせて含む抗糖尿病薬 |
KR102668834B1 (ko) * | 2009-11-27 | 2024-05-24 | 베링거 인겔하임 인터내셔날 게엠베하 | 리나글립틴과 같은 dpp-iv 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료 |
US9572806B2 (en) * | 2009-12-18 | 2017-02-21 | Mitsubishi Tanabe Pharma Corporation | Elution-stabilized preparation |
RU2654069C2 (ru) * | 2012-08-31 | 2018-05-16 | Гленмарк Фармасьютикалс Лимитед | Способ получения тенелиглиптина |
JP6088872B2 (ja) * | 2013-03-22 | 2017-03-01 | サラヤ株式会社 | ラクトン型ソホロリピッドの分解が抑制されたソホロリピッド粉末 |
WO2015012365A1 (ja) * | 2013-07-25 | 2015-01-29 | 株式会社 三和化学研究所 | 医薬製剤 |
WO2015019238A1 (en) * | 2013-08-06 | 2015-02-12 | Ranbaxy Laboratories Limited | Process for the preparation of n-protected (5s)-5-(1,3-thiazolidin-3-ylcarbonyl)pyrrolidin-3-one |
CN104650065A (zh) * | 2013-11-22 | 2015-05-27 | 天津市汉康医药生物技术有限公司 | 一种替格列汀化合物 |
WO2015132679A1 (en) * | 2014-03-05 | 2015-09-11 | Glenmark Pharmaceuticals Ltd | Teneligliptin compositions |
WO2015173779A1 (en) * | 2014-05-16 | 2015-11-19 | Micro Labs Limited | Process for the preparation of teneligliptin and its novel intermediates |
CN105294673B (zh) * | 2014-06-18 | 2018-04-13 | 四川科伦药物研究院有限公司 | 一种氢溴酸替格列汀的合成方法 |
EP3201191A1 (en) * | 2014-10-01 | 2017-08-09 | Mylan Laboratories Ltd. | Complex of amorphous empagliflozin and a cyclodextrin |
JP6027710B1 (ja) * | 2014-12-25 | 2016-11-16 | 田辺三菱製薬株式会社 | 糖尿病治療用固形製剤 |
-
2018
- 2018-02-02 CN CN201880000427.8A patent/CN108884089A/zh active Pending
- 2018-02-02 AU AU2018202623A patent/AU2018202623A1/en not_active Abandoned
- 2018-02-02 WO PCT/IB2018/050662 patent/WO2018142334A1/en active Application Filing
- 2018-02-02 EA EA201992376A patent/EA039402B1/ru unknown
- 2018-02-02 WO PCT/IB2018/050652 patent/WO2018142327A1/en active Application Filing
- 2018-02-02 RU RU2018120216A patent/RU2018120216A/ru unknown
- 2018-02-02 CN CN201880000703.0A patent/CN108697707A/zh active Pending
- 2018-02-02 MX MX2018006005A patent/MX2018006005A/es unknown
- 2018-02-02 KR KR1020187016406A patent/KR20180100554A/ko not_active Application Discontinuation
- 2018-02-02 JP JP2018536796A patent/JP2019508385A/ja active Pending
- 2018-02-02 BR BR112018010748A patent/BR112018010748A2/pt not_active IP Right Cessation
- 2018-02-02 RU RU2018120214A patent/RU2742418C1/ru active
- 2018-02-02 MX MX2018006006A patent/MX2018006006A/es unknown
- 2018-02-02 KR KR1020187013773A patent/KR20180099635A/ko not_active IP Right Cessation
- 2018-02-02 JP JP2018537629A patent/JP2019512460A/ja active Pending
- 2018-02-02 AU AU2018202960A patent/AU2018202960A1/en not_active Abandoned
- 2018-02-02 TW TW107103863A patent/TW201831473A/zh unknown
- 2018-02-02 BR BR112018010759A patent/BR112018010759A2/pt not_active IP Right Cessation
- 2018-02-05 TW TW107104026A patent/TW201834655A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
RU2742418C1 (ru) | 2021-02-05 |
RU2018120216A (ru) | 2021-05-07 |
EA039402B1 (ru) | 2022-01-24 |
KR20180099635A (ko) | 2018-09-05 |
AU2018202623A1 (en) | 2018-08-23 |
JP2019512460A (ja) | 2019-05-16 |
AU2018202960A1 (en) | 2018-08-23 |
BR112018010748A2 (pt) | 2018-12-04 |
BR112018010759A2 (pt) | 2018-12-04 |
TW201834655A (zh) | 2018-10-01 |
WO2018142327A1 (en) | 2018-08-09 |
TW201831473A (zh) | 2018-09-01 |
JP2019508385A (ja) | 2019-03-28 |
CN108884089A (zh) | 2018-11-23 |
CN108697707A (zh) | 2018-10-23 |
MX2018006006A (es) | 2019-05-16 |
EA201992376A1 (ru) | 2020-03-23 |
WO2018142334A1 (en) | 2018-08-09 |
KR20180100554A (ko) | 2018-09-11 |
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