MX2018003983A - Metodo de tratamiento de trastornos asociados a la via del receptor de melanocortina-4. - Google Patents

Metodo de tratamiento de trastornos asociados a la via del receptor de melanocortina-4.

Info

Publication number
MX2018003983A
MX2018003983A MX2018003983A MX2018003983A MX2018003983A MX 2018003983 A MX2018003983 A MX 2018003983A MX 2018003983 A MX2018003983 A MX 2018003983A MX 2018003983 A MX2018003983 A MX 2018003983A MX 2018003983 A MX2018003983 A MX 2018003983A
Authority
MX
Mexico
Prior art keywords
treating
associated disorders
receptor pathway
subject
melanocortin
Prior art date
Application number
MX2018003983A
Other languages
English (en)
Spanish (es)
Inventor
H T Van Der Ploeg Leonardus
Henderson Bart
Kuhnen Peter
Original Assignee
Rhythm Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhythm Pharmaceuticals Inc filed Critical Rhythm Pharmaceuticals Inc
Publication of MX2018003983A publication Critical patent/MX2018003983A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • C07K14/685—Alpha-melanotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MX2018003983A 2015-09-30 2016-09-29 Metodo de tratamiento de trastornos asociados a la via del receptor de melanocortina-4. MX2018003983A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562235003P 2015-09-30 2015-09-30
PCT/US2016/054457 WO2017059076A1 (en) 2015-09-30 2016-09-29 Method of treating melanocortin-4 receptor pathway-associated disorders

Publications (1)

Publication Number Publication Date
MX2018003983A true MX2018003983A (es) 2018-11-09

Family

ID=57138146

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2018003983A MX2018003983A (es) 2015-09-30 2016-09-29 Metodo de tratamiento de trastornos asociados a la via del receptor de melanocortina-4.
MX2023003358A MX2023003358A (es) 2015-09-30 2018-03-28 Agonista del receptor de melanocortina-4 (mc4r) para el tratamiento de trastornos asociados a la via del mc4r.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2023003358A MX2023003358A (es) 2015-09-30 2018-03-28 Agonista del receptor de melanocortina-4 (mc4r) para el tratamiento de trastornos asociados a la via del mc4r.

Country Status (20)

Country Link
US (5) US10960046B2 (enExample)
EP (5) EP4711004A3 (enExample)
JP (8) JP7051106B2 (enExample)
KR (1) KR20180063221A (enExample)
CN (2) CN108601816A (enExample)
AU (6) AU2016330772A1 (enExample)
BR (1) BR112018006674A2 (enExample)
CA (3) CA3000670A1 (enExample)
DK (1) DK3356386T3 (enExample)
ES (1) ES2985734T3 (enExample)
FI (1) FI3356386T3 (enExample)
HK (1) HK1259424A1 (enExample)
IL (3) IL299541A (enExample)
MA (2) MA43040A (enExample)
MX (2) MX2018003983A (enExample)
PL (1) PL3356386T3 (enExample)
PT (1) PT3356386T (enExample)
SG (1) SG10202101510XA (enExample)
WO (2) WO2017059076A1 (enExample)
ZA (1) ZA201802704B (enExample)

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JP2024532294A (ja) * 2021-08-24 2024-09-05 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン Ｍｃ４ｒアゴニストペプチド
KR20250106335A (ko) * 2022-07-12 2025-07-09 리듬 파마슈티컬즈, 인코포레이티드 Mc4r 효능제로 비만을 치료하는 방법
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KR20250127061A (ko) * 2022-11-18 2025-08-26 리듬 파마슈티컬즈, 인코포레이티드 Mc4r 작용제를 이용한 비만 치료 방법
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Also Published As

Publication number Publication date
JP2021102650A (ja) 2021-07-15
JP2025019234A (ja) 2025-02-06
AU2021201448A1 (en) 2021-03-25
KR20180063221A (ko) 2018-06-11
JP7051106B2 (ja) 2022-04-11
US20250195606A1 (en) 2025-06-19
JP2018531937A (ja) 2018-11-01
IL289996B2 (en) 2023-07-01
US20180311309A1 (en) 2018-11-01
JP2021088611A (ja) 2021-06-10
JP2018531938A (ja) 2018-11-01
MA43040A (fr) 2018-08-08
AU2024278597A1 (en) 2025-01-16
EP3355905A1 (en) 2018-08-08
PL3356386T3 (pl) 2024-08-05
CA3000670A1 (en) 2017-04-06
EP4029513A1 (en) 2022-07-20
EP4360704A3 (en) 2024-07-24
US10960046B2 (en) 2021-03-30
FI3356386T3 (fi) 2024-05-16
JP2023078335A (ja) 2023-06-06
DK3356386T3 (da) 2024-05-21
IL299541A (en) 2023-02-01
ES2985734T3 (es) 2024-11-07
US20220226425A1 (en) 2022-07-21
EP3356386A1 (en) 2018-08-08
AU2022279420B2 (en) 2024-09-19
WO2017059076A1 (en) 2017-04-06
US12263202B2 (en) 2025-04-01
BR112018006674A2 (en) 2018-10-09
US20180215790A1 (en) 2018-08-02
WO2017059075A1 (en) 2017-04-06
IL289996A (en) 2022-03-01
CN108431023B (zh) 2022-11-04
IL258412A (en) 2018-05-31
JP2026042856A (ja) 2026-03-11
JP2022173426A (ja) 2022-11-18
MA43038A (fr) 2018-08-08
US20210169970A1 (en) 2021-06-10
JP7752373B2 (ja) 2025-10-10
EP4711004A3 (en) 2026-05-27
CN108601816A (zh) 2018-09-28
PT3356386T (pt) 2024-05-17
AU2022279420A1 (en) 2023-01-19
EP4360704A2 (en) 2024-05-01
WO2017059076A8 (en) 2018-04-26
IL258412B2 (en) 2023-06-01
JP6940853B2 (ja) 2021-09-29
EP4711004A2 (en) 2026-03-18
CN108431023A (zh) 2018-08-21
ZA201802704B (en) 2024-08-28
HK1259424A1 (zh) 2019-11-29
CA3302750A1 (en) 2026-05-13
IL289996B1 (en) 2023-03-01
CA3000673A1 (en) 2017-04-06
AU2016330772A1 (en) 2018-04-19
SG10202101510XA (en) 2021-03-30
AU2016330773A1 (en) 2018-04-19
MX2023003358A (es) 2023-03-29
EP3356386B1 (en) 2024-02-14
AU2023229494A1 (en) 2023-09-28

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