PL3356386T3 - Sposób leczenia zaburzeń związanych ze szlakiem receptora melanokortyny 4 - Google Patents

Sposób leczenia zaburzeń związanych ze szlakiem receptora melanokortyny 4

Info

Publication number
PL3356386T3
PL3356386T3 PL16782150.3T PL16782150T PL3356386T3 PL 3356386 T3 PL3356386 T3 PL 3356386T3 PL 16782150 T PL16782150 T PL 16782150T PL 3356386 T3 PL3356386 T3 PL 3356386T3
Authority
PL
Poland
Prior art keywords
associated disorders
receptor pathway
treating melanocortin
melanocortin
treating
Prior art date
Application number
PL16782150.3T
Other languages
English (en)
Polish (pl)
Inventor
Shubh Sharma
Leonardus H.T. Van Der Ploeg
Bart Henderson
Original Assignee
Rhythm Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhythm Pharmaceuticals, Inc. filed Critical Rhythm Pharmaceuticals, Inc.
Publication of PL3356386T3 publication Critical patent/PL3356386T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68Melanocyte-stimulating hormone [MSH]
    • C07K14/685Alpha-melanotropin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL16782150.3T 2015-09-30 2016-09-29 Sposób leczenia zaburzeń związanych ze szlakiem receptora melanokortyny 4 PL3356386T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562235003P 2015-09-30 2015-09-30
PCT/US2016/054455 WO2017059075A1 (en) 2015-09-30 2016-09-29 Method of treating melanocortin-4 receptor pathway-associated disorders

Publications (1)

Publication Number Publication Date
PL3356386T3 true PL3356386T3 (pl) 2024-08-05

Family

ID=57138146

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16782150.3T PL3356386T3 (pl) 2015-09-30 2016-09-29 Sposób leczenia zaburzeń związanych ze szlakiem receptora melanokortyny 4

Country Status (20)

Country Link
US (5) US20180215790A1 (enExample)
EP (5) EP4711004A2 (enExample)
JP (8) JP7051106B2 (enExample)
KR (1) KR20180063221A (enExample)
CN (2) CN108601816A (enExample)
AU (6) AU2016330772A1 (enExample)
BR (1) BR112018006674A2 (enExample)
CA (2) CA3000670A1 (enExample)
DK (1) DK3356386T3 (enExample)
ES (1) ES2985734T3 (enExample)
FI (1) FI3356386T3 (enExample)
HK (1) HK1259424A1 (enExample)
IL (3) IL299541A (enExample)
MA (2) MA43040A (enExample)
MX (2) MX2018003983A (enExample)
PL (1) PL3356386T3 (enExample)
PT (1) PT3356386T (enExample)
SG (1) SG10202101510XA (enExample)
WO (2) WO2017059076A1 (enExample)
ZA (1) ZA201802704B (enExample)

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WO2019162312A1 (en) 2018-02-20 2019-08-29 Charité - Universitätsmedizin Berlin Mc4r agonist efficacy in subjects with mc4r deficiencies and impaired nfat signaling
WO2019219714A1 (en) 2018-05-15 2019-11-21 Novo Nordisk A/S Compounds capable of binding to melanocortin 4 receptor
CN108841932B (zh) * 2018-07-13 2021-03-12 东北农业大学 一种预示和鉴定鸡腹部脂肪量的分子标记方法及应用
WO2021225972A1 (en) * 2020-05-04 2021-11-11 Regeneron Pharmaceuticals, Inc. Proprotein convertase subtilisin/kexin type 1 (pcsk1) variants and uses thereof
EP4216979A4 (en) * 2020-09-24 2024-11-06 Rhythm Pharmaceuticals, Inc. Methods of treating melanocortin-4 receptor pathway-associated disorders
EP4392072A4 (en) * 2021-08-24 2026-03-04 Univ Michigan Regents MC4R AGONIST PEPTIDES
WO2024083843A1 (en) 2022-10-18 2024-04-25 Confo Therapeutics N.V. Amino acid sequences directed against the melanocortin 4 receptor and polypeptides comprising the same for the treatment of mc4r-related diseases and disorders
CN120731088A (zh) * 2022-11-18 2025-09-30 节奏制药公司 用mc4r激动剂治疗肥胖症的方法
WO2024155828A1 (en) * 2023-01-18 2024-07-25 Loma Linda University Health Uses of aminopyridines in the management of weight and satiety
CN117143183B (zh) * 2023-08-25 2024-08-16 广州益养生物科技有限公司 一种三肽、三肽盐或衍生物及其应用
WO2026022136A1 (en) * 2024-07-23 2026-01-29 Proqr Therapeutics Ii B.V. Antisense oligonucleotides for the treatment of metabolic disorders

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Also Published As

Publication number Publication date
EP4711004A2 (en) 2026-03-18
BR112018006674A2 (en) 2018-10-09
JP2018531938A (ja) 2018-11-01
WO2017059076A1 (en) 2017-04-06
WO2017059075A1 (en) 2017-04-06
MA43040A (fr) 2018-08-08
AU2016330772A1 (en) 2018-04-19
IL258412B2 (en) 2023-06-01
CN108431023B (zh) 2022-11-04
CA3000670A1 (en) 2017-04-06
JP2022173426A (ja) 2022-11-18
JP2018531937A (ja) 2018-11-01
AU2016330773A1 (en) 2018-04-19
CN108431023A (zh) 2018-08-21
EP3356386B1 (en) 2024-02-14
SG10202101510XA (en) 2021-03-30
JP2026042856A (ja) 2026-03-11
AU2022279420A1 (en) 2023-01-19
US20210169970A1 (en) 2021-06-10
JP2021088611A (ja) 2021-06-10
CN108601816A (zh) 2018-09-28
CA3000673A1 (en) 2017-04-06
WO2017059076A8 (en) 2018-04-26
US20220226425A1 (en) 2022-07-21
IL299541A (en) 2023-02-01
EP4029513A1 (en) 2022-07-20
US20180215790A1 (en) 2018-08-02
DK3356386T3 (da) 2024-05-21
US12263202B2 (en) 2025-04-01
US20250195606A1 (en) 2025-06-19
AU2022279420B2 (en) 2024-09-19
JP7752373B2 (ja) 2025-10-10
IL289996B1 (en) 2023-03-01
AU2023229494A1 (en) 2023-09-28
EP3356386A1 (en) 2018-08-08
MX2018003983A (es) 2018-11-09
ES2985734T3 (es) 2024-11-07
IL289996B2 (en) 2023-07-01
IL258412A (en) 2018-05-31
EP4360704A2 (en) 2024-05-01
JP7051106B2 (ja) 2022-04-11
MX2023003358A (es) 2023-03-29
US10960046B2 (en) 2021-03-30
IL289996A (en) 2022-03-01
EP3355905A1 (en) 2018-08-08
ZA201802704B (en) 2024-08-28
JP6940853B2 (ja) 2021-09-29
JP2021102650A (ja) 2021-07-15
AU2024278597A1 (en) 2025-01-16
MA43038A (fr) 2018-08-08
AU2021201448A1 (en) 2021-03-25
US20180311309A1 (en) 2018-11-01
HK1259424A1 (zh) 2019-11-29
EP4360704A3 (en) 2024-07-24
JP2023078335A (ja) 2023-06-06
JP2025019234A (ja) 2025-02-06
KR20180063221A (ko) 2018-06-11
FI3356386T3 (fi) 2024-05-16
PT3356386T (pt) 2024-05-17

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