MX2017010357A - Derivados novedosos de n-acil-arilsulfonamida como inhibidores de aminoacil acido ribonucleico de transferencia (arnt) sintetasa. - Google Patents

Derivados novedosos de n-acil-arilsulfonamida como inhibidores de aminoacil acido ribonucleico de transferencia (arnt) sintetasa.

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Publication number
MX2017010357A
MX2017010357A MX2017010357A MX2017010357A MX2017010357A MX 2017010357 A MX2017010357 A MX 2017010357A MX 2017010357 A MX2017010357 A MX 2017010357A MX 2017010357 A MX2017010357 A MX 2017010357A MX 2017010357 A MX2017010357 A MX 2017010357A
Authority
MX
Mexico
Prior art keywords
acyl
novel
aminoacyl
trna synthetase
synthetase inhibitors
Prior art date
Application number
MX2017010357A
Other languages
English (en)
Inventor
Jirgensons Aigars
Loza Einars
Ribas De Pouplana Lluis
Saint-Leger Adelaide
Charlton Michael
William Finn Paul
Original Assignee
Oxford Drug Design Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from LVP-15-14A external-priority patent/LV15146B/lv
Priority claimed from LVP-16-06A external-priority patent/LV15257A/lv
Application filed by Oxford Drug Design Ltd filed Critical Oxford Drug Design Ltd
Publication of MX2017010357A publication Critical patent/MX2017010357A/es

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

La presente invención se relaciona con N-acil-diarisulfonamidas novedosas que funcionan como inhibidores de la aminoacil-ARNt sintetasa bacteriana. Estas se pueden utilizar como medicinas o como constituyentes de medicinas para el tratamiento de infecciones bacterianas.
MX2017010357A 2015-02-13 2016-02-11 Derivados novedosos de n-acil-arilsulfonamida como inhibidores de aminoacil acido ribonucleico de transferencia (arnt) sintetasa. MX2017010357A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
LVP-15-14A LV15146B (lv) 2015-02-13 2015-02-13 N-acil-diarilsulfonamīda atvasinājumi kā aminoacil-t-RNS sintetāžu inhibitori
LVP-16-06A LV15257A (lv) 2016-02-10 2016-02-10 Jauni N-acil-arilsulfonamīda atvasinājumi kā aminoacil-tRNS sintetāzes inhibitori
PCT/LV2016/000001 WO2016129983A1 (en) 2015-02-13 2016-02-11 Novel n-acyl-arylsulfonamide derivatives as aminoacyl-trna synthetase inhibitors

Publications (1)

Publication Number Publication Date
MX2017010357A true MX2017010357A (es) 2018-04-24

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MX2017010357A MX2017010357A (es) 2015-02-13 2016-02-11 Derivados novedosos de n-acil-arilsulfonamida como inhibidores de aminoacil acido ribonucleico de transferencia (arnt) sintetasa.

Country Status (13)

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US (1) US11072581B2 (es)
EP (1) EP3259250A1 (es)
JP (1) JP6740256B2 (es)
KR (1) KR102568859B1 (es)
CN (1) CN107257789B (es)
AU (1) AU2016216782C1 (es)
CA (1) CA2975682A1 (es)
EA (1) EA036995B1 (es)
IL (1) IL253886B (es)
MA (1) MA41542A (es)
MX (1) MX2017010357A (es)
WO (1) WO2016129983A1 (es)
ZA (1) ZA201706108B (es)

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GB201617064D0 (en) * 2016-10-07 2016-11-23 Inhibox Limited And Latvian Institute Of Organic Synthesis The Compounds and their therapeutic use
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TW202120490A (zh) 2019-07-30 2021-06-01 德商拜耳動物保健有限公司 新穎異喹啉衍生物
CN112759542B (zh) * 2019-11-04 2022-04-01 上海现代制药股份有限公司 一种药物中间体及其制备和应用
CN110950863B (zh) * 2019-11-15 2021-04-02 中山大学 一种喹唑啉酮类化合物及其制备方法和应用
IL293964A (en) * 2019-12-19 2022-08-01 Oxford Drug Design Ltd 2-amino-n-(amino-oxo-aryl-lambda 6-sulfanilidene)acetamide compounds and their therapeutic use

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KR102568859B1 (ko) 2015-02-13 2023-08-21 옥스포드 드러그 디자인 리미티드 아미노아실-tRNA 합성효소 저해제로서 신규한 N-아실-아릴술폰아미드 유도체
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US11072581B2 (en) 2021-07-27
CA2975682A1 (en) 2016-08-18
AU2016216782C1 (en) 2021-02-18
WO2016129983A1 (en) 2016-08-18
EA036995B1 (ru) 2021-01-25
KR102568859B1 (ko) 2023-08-21
KR20170118106A (ko) 2017-10-24
AU2016216782B2 (en) 2020-07-30
CN107257789A (zh) 2017-10-17
IL253886A0 (en) 2017-10-31
ZA201706108B (en) 2019-02-27
IL253886B (en) 2020-01-30
EA201791530A1 (ru) 2018-01-31
JP6740256B2 (ja) 2020-08-12
JP2018507257A (ja) 2018-03-15
BR112017016977A2 (pt) 2018-04-03
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EP3259250A1 (en) 2017-12-27
AU2016216782A1 (en) 2017-09-28

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