MX2017001824A - Mutaciones en proteinas del grupo hierro-azufre que mejoran la utilizacion de xilosa. - Google Patents

Mutaciones en proteinas del grupo hierro-azufre que mejoran la utilizacion de xilosa.

Info

Publication number
MX2017001824A
MX2017001824A MX2017001824A MX2017001824A MX2017001824A MX 2017001824 A MX2017001824 A MX 2017001824A MX 2017001824 A MX2017001824 A MX 2017001824A MX 2017001824 A MX2017001824 A MX 2017001824A MX 2017001824 A MX2017001824 A MX 2017001824A
Authority
MX
Mexico
Prior art keywords
mutations
iron
xylose utilization
sulfur cluster
improve xylose
Prior art date
Application number
MX2017001824A
Other languages
English (en)
Inventor
Froehlich Allan
HENNINGSEN Brooks
COVALLA Sean
M Zelle Rintze
Original Assignee
Lallemand Hungary Liquidity Man Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lallemand Hungary Liquidity Man Llc filed Critical Lallemand Hungary Liquidity Man Llc
Publication of MX2017001824A publication Critical patent/MX2017001824A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y503/00—Intramolecular oxidoreductases (5.3)
    • C12Y503/01—Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
    • C12Y503/01005—Xylose isomerase (5.3.1.5)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Se proveen células hospederas genéticamente manipuladas que comprenden (a) una o más mutaciones en uno o más genes endógenos que codifican una proteína asociada con el metabolismo del hierro; y (b) por lo menos gen que codifica un polipéptido que tiene actividad de xilosa isomerasa, y métodos de uso de las mismas.
MX2017001824A 2014-08-11 2015-08-11 Mutaciones en proteinas del grupo hierro-azufre que mejoran la utilizacion de xilosa. MX2017001824A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462035748P 2014-08-11 2014-08-11
PCT/IB2015/056101 WO2016024215A1 (en) 2014-08-11 2015-08-11 Mutations in iron-sulfur cluster proteins that improve xylose utilization

Publications (1)

Publication Number Publication Date
MX2017001824A true MX2017001824A (es) 2017-05-23

Family

ID=54186239

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017001824A MX2017001824A (es) 2014-08-11 2015-08-11 Mutaciones en proteinas del grupo hierro-azufre que mejoran la utilizacion de xilosa.

Country Status (7)

Country Link
US (3) US9920312B2 (es)
EP (1) EP3180419A1 (es)
CN (1) CN108064269A (es)
BR (1) BR112017002549A2 (es)
CA (1) CA2957707C (es)
MX (1) MX2017001824A (es)
WO (1) WO2016024215A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10508272B2 (en) * 2014-04-11 2019-12-17 Wisconsin Alumni Research Foundation Recombinant yeast having enhanced xylose fermentation capabilities and methods of use
US10006057B2 (en) * 2014-09-10 2018-06-26 Wisconsin Alumni Research Foundation Recombinant yeast having enhanced gamma valerolactone tolerance and methods of use
BR112018068981A2 (pt) 2016-03-18 2019-04-16 Lallemand Hungary Liquidity Management Llc regulação da rota de sinalização de ras/camp/pka em leveduras
WO2018073107A1 (en) * 2016-10-19 2018-04-26 Dsm Ip Assets B.V. Eukaryotic cell comprising xylose isomerase
CA3091962A1 (en) 2017-09-19 2019-03-28 Lallemand Hungary Liquidity Management Llc Acetate toxicity tolerance in recombinant microbial host cells
CN113736675B (zh) * 2020-05-29 2023-11-21 中国科学院分子植物科学卓越创新中心 一种提高酿酒酵母转化木糖能力的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102186983A (zh) * 2008-09-29 2011-09-14 布特马斯先进生物燃料有限责任公司 酵母中提高的异源Fe-S酶活性
CA2781131C (en) 2009-11-24 2017-01-03 Gevo, Inc. Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids
CN102947440B (zh) * 2009-12-30 2015-04-08 埃欧金能源公司 呈现增强的木质纤维素水解产物发酵的改良酵母菌株
US9297016B2 (en) 2010-02-17 2016-03-29 Butamax Advanced Biofuels Llc Activity of Fe—S cluster requiring proteins
WO2012071121A1 (en) 2010-11-24 2012-05-31 Gevo, Inc. Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids
WO2012097091A2 (en) 2011-01-12 2012-07-19 Verdezyne, Inc. Engineered microorganisms with enhanced fermentation activity
WO2012135591A2 (en) * 2011-03-30 2012-10-04 Amyris, Inc. Microbial isoprenoid production using a heterologous dxp pathway
CN103649321B (zh) 2011-04-05 2019-07-16 拉勒曼德匈牙利流动性管理有限责任公司 用于通过添加交替电子受体改善微生物中的产品收率和产量的方法
BR112013033614A2 (pt) 2011-06-30 2018-05-29 Codexis Inc fermentação de pentose por microorganismo recombinante
CN104321436A (zh) * 2011-12-30 2015-01-28 布特马斯先进生物燃料有限责任公司 醇类的发酵生产
WO2013138339A1 (en) 2012-03-15 2013-09-19 Codexis, Inc. Gene shuffling methods
WO2014106107A2 (en) * 2012-12-28 2014-07-03 Butamax (Tm) Advanced Biofuels Llc Dhad variants for butanol production
US10508272B2 (en) 2014-04-11 2019-12-17 Wisconsin Alumni Research Foundation Recombinant yeast having enhanced xylose fermentation capabilities and methods of use

Also Published As

Publication number Publication date
US20160040153A1 (en) 2016-02-11
US20180251750A1 (en) 2018-09-06
US9920312B2 (en) 2018-03-20
CA2957707C (en) 2022-05-10
US11306304B2 (en) 2022-04-19
BR112017002549A2 (pt) 2018-03-06
CN108064269A (zh) 2018-05-22
EP3180419A1 (en) 2017-06-21
US10465181B2 (en) 2019-11-05
US20200115697A1 (en) 2020-04-16
WO2016024215A1 (en) 2016-02-18
CA2957707A1 (en) 2016-02-18

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