MX2016013964A - Receptores de antigenos quimericos del promotor mnd. - Google Patents

Receptores de antigenos quimericos del promotor mnd.

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Publication number
MX2016013964A
MX2016013964A MX2016013964A MX2016013964A MX2016013964A MX 2016013964 A MX2016013964 A MX 2016013964A MX 2016013964 A MX2016013964 A MX 2016013964A MX 2016013964 A MX2016013964 A MX 2016013964A MX 2016013964 A MX2016013964 A MX 2016013964A
Authority
MX
Mexico
Prior art keywords
chimeric antigen
antigen receptors
mnd promoter
promoter chimeric
mnd
Prior art date
Application number
MX2016013964A
Other languages
English (en)
Inventor
Morgan Richard
friedman Kevin
RYU Byoung
Original Assignee
Bluebird Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54333432&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2016013964(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bluebird Bio Inc filed Critical Bluebird Bio Inc
Publication of MX2016013964A publication Critical patent/MX2016013964A/es

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    • C—CHEMISTRY; METALLURGY
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    • C07K2319/00—Fusion polypeptide
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
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    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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Abstract

Se proporcionan composiciones de vector que comprenden un promotor de potenciador del virus de sarcoma mieloproliferativo, región de control negativo eliminada, sustituido en el sitio de unión al iniciador dl587rev (MND) enlazado operativamente con un receptor de antígeno quimérico (CAR).
MX2016013964A 2014-04-25 2015-04-24 Receptores de antigenos quimericos del promotor mnd. MX2016013964A (es)

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