IL125884A0 - Modified rapid expansion methods ("modified-rem") for in vitro propagation of t lymphocytes - Google Patents

Modified rapid expansion methods ("modified-rem") for in vitro propagation of t lymphocytes

Info

Publication number
IL125884A0
IL125884A0 IL12588497A IL12588497A IL125884A0 IL 125884 A0 IL125884 A0 IL 125884A0 IL 12588497 A IL12588497 A IL 12588497A IL 12588497 A IL12588497 A IL 12588497A IL 125884 A0 IL125884 A0 IL 125884A0
Authority
IL
Israel
Prior art keywords
modified
rem
lymphocytes
rapid expansion
expansion methods
Prior art date
Application number
IL12588497A
Original Assignee
Targeted Genetics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Targeted Genetics Corp filed Critical Targeted Genetics Corp
Publication of IL125884A0 publication Critical patent/IL125884A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/515—CD3, T-cell receptor complex
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/58—Adhesion molecules, e.g. ICAM, VCAM, CD18 (ligand), CD11 (ligand), CD49 (ligand)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL12588497A 1996-03-04 1997-03-03 Modified rapid expansion methods ("modified-rem") for in vitro propagation of t lymphocytes IL125884A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61071096A 1996-03-04 1996-03-04
PCT/US1997/003293 WO1997032970A1 (en) 1996-03-04 1997-03-03 Modified rapid expansion methods ('modified-rem') for in vitro propagation of t lymphocytes

Publications (1)

Publication Number Publication Date
IL125884A0 true IL125884A0 (en) 1999-04-11

Family

ID=24446115

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12588497A IL125884A0 (en) 1996-03-04 1997-03-03 Modified rapid expansion methods ("modified-rem") for in vitro propagation of t lymphocytes

Country Status (4)

Country Link
AU (1) AU726198B2 (en)
CA (1) CA2247131A1 (en)
IL (1) IL125884A0 (en)
WO (1) WO1997032970A1 (en)

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JP4389039B2 (en) * 1998-04-09 2009-12-24 株式会社リンフォテック PHARMACEUTICAL COMPOSITION CONTAINING ALLOGENIC ACTIVATED CD4-POSITIVE CELLS AS MAIN COMPONENTS, PROCESS FOR PRODUCING THE SAME AND KIT FOR PREPARING THE PHARMACEUTICAL COMPOSITION
US7541184B2 (en) 2000-02-24 2009-06-02 Invitrogen Corporation Activation and expansion of cells
US7572631B2 (en) 2000-02-24 2009-08-11 Invitrogen Corporation Activation and expansion of T cells
JP4231688B2 (en) * 2000-08-16 2009-03-04 タカラバイオ株式会社 Antigen-specific cytotoxic T cell expansion culture method
US20040071671A1 (en) 2001-02-20 2004-04-15 Leturcq Didier J. Cell therapy method for the treatment of tumors
HUP0402656A3 (en) * 2001-02-20 2012-03-28 Ortho Mcneil Pharm Inc A cell therapy method for the treatment of tumors
DE10120505A1 (en) * 2001-04-26 2002-11-07 Rudolf Wank Use of stimulated peripheral blood mononuclear cells for the treatment of cancer
TWI311586B (en) * 2001-08-15 2009-07-01 Takara Bio Inc Method of extended culture for antigen-specific cytotoxic t lumphocytes
EP2305796B1 (en) 2002-03-25 2012-10-24 Takara Bio Inc. Process for producing cytotoxic lymphocytes
JP4562353B2 (en) * 2002-04-08 2010-10-13 株式会社リンフォテック Formulation for prevention / treatment of tumors / infections and autoimmune diseases comprising activated lymphocytes derived from HLA-matched others
US20050084967A1 (en) 2002-06-28 2005-04-21 Xcyte Therapies, Inc. Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
WO2004078928A2 (en) 2003-02-28 2004-09-16 The Johns Hopkins University T cell regulation
KR101331746B1 (en) 2003-08-22 2013-11-20 다카라 바이오 가부시키가이샤 Process for producing cytotoxic lymphocytes
EP1916302A4 (en) 2005-08-17 2009-10-21 Takara Bio Inc PROCESS FOR THE PRODUCTION OF LYMPHOCYTES
WO2007142300A1 (en) 2006-06-09 2007-12-13 Takara Bio Inc. Method of producing lymphocytes
JP5666903B2 (en) * 2007-05-23 2015-02-12 サンガモ バイオサイエンシーズ， インコーポレイテッド Methods and compositions for enhancing transgene expression
EP2794859B1 (en) * 2011-12-22 2017-09-20 Mogam Biotechnology Institute Method for producing natural killer cells, natural killer cells produced thereby, and composition for treating cancers and infectious diseases containing the same
KR20160068960A (en) 2013-10-25 2016-06-15 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 Polyclonal gamma delta t cells for immunotherapy
PL3689899T3 (en) 2014-04-25 2022-01-31 2Seventy Bio, Inc. CHIMERIC ANTIGEN RECEPTORS OF THE MND PROMOTER
CA2946552A1 (en) * 2014-04-25 2015-10-29 Bluebird Bio, Inc. Improved methods for manufacturing adoptive cell therapies
DK3151672T3 (en) 2014-06-06 2021-02-01 Bluebird Bio Inc IMPROVED T-CELL COMPOSITIONS
MX2017001079A (en) 2014-07-24 2017-09-12 Bluebird Bio Inc Bcma chimeric antigen receptors.
KR101697473B1 (en) 2014-11-26 2017-01-18 주식회사 녹십자랩셀 Method for Preparation of Natural Killer Cells Using T Cells
SMT201900596T1 (en) 2014-12-12 2019-11-13 Bluebird Bio Inc Bcma chimeric antigen receptors
WO2017099712A1 (en) 2015-12-07 2017-06-15 Bluebird Bio, Inc. Improved t cell compositions
BR112019009099A2 (en) 2016-11-04 2019-07-16 Bluebird Bio Inc anti-bcma t cell compositions
JP7039623B2 (en) 2017-05-26 2022-03-22 グリーン・クロス・ラブ・セル・コーポレイション Method of culturing natural killer cells using transformed T cells
AU2019381526B2 (en) 2018-11-14 2023-02-23 Green Cross Lab Cell Corporation Method for culturing cord blood-derived natural killer cells using transformed T-cells

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02502424A (en) * 1987-03-11 1990-08-09 ザ・チルドレンズ・ホスピタル，インコーポレイテッド Methods for the preparation of antigen-specific T cell lines and their use for therapy
US5057423A (en) 1987-12-18 1991-10-15 University Of Pittsburgh Method for the preparation of pure LAK-active lymphocytes
ZA91463B (en) * 1990-01-25 1992-09-30 Bristol Myers Squibb Co Method of activating cytolytic activity of lymphocytes using anti-cd28 antibody
WO1992005794A1 (en) * 1990-09-28 1992-04-16 Immunex Corporation Method for producing th-independent cytotoxic t lymphocytes
DK0557459T3 (en) * 1990-11-13 1997-12-15 Immunex Corp Bifunctional, selectable fusion genes
DE4410136A1 (en) * 1993-03-31 1994-10-06 Boehringer Mannheim Gmbh Tumoricidal T lymphocytes
US5827642A (en) * 1994-08-31 1998-10-27 Fred Hutchinson Cancer Research Center Rapid expansion method ("REM") for in vitro propagation of T lymphocytes

Also Published As

Publication number Publication date
WO1997032970A1 (en) 1997-09-12
AU2194797A (en) 1997-09-22
AU726198B2 (en) 2000-11-02
CA2247131A1 (en) 1997-09-12

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