MX2016004128A - Proceso para preparar xanthohumol. - Google Patents

Proceso para preparar xanthohumol.

Info

Publication number
MX2016004128A
MX2016004128A MX2016004128A MX2016004128A MX2016004128A MX 2016004128 A MX2016004128 A MX 2016004128A MX 2016004128 A MX2016004128 A MX 2016004128A MX 2016004128 A MX2016004128 A MX 2016004128A MX 2016004128 A MX2016004128 A MX 2016004128A
Authority
MX
Mexico
Prior art keywords
xanthohumol
preparation
dried
collected
mixed
Prior art date
Application number
MX2016004128A
Other languages
English (en)
Other versions
MX362188B (es
Inventor
Gagos Mariusz
Original Assignee
Axen Bio Group Sp Z O O
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axen Bio Group Sp Z O O filed Critical Axen Bio Group Sp Z O O
Publication of MX2016004128A publication Critical patent/MX2016004128A/es
Publication of MX362188B publication Critical patent/MX362188B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/85—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to a chemical modification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/86—Use of additives, e.g. for stabilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/213—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C49/215—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/782—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

La invención proporciona un proceso para la preparación de xanthohumol, en donde un extracto que contiene xanthohumol se mezcla con agua, una solución de sal de metal de transición se añade a la mezcla obtenida, y después el precipitado de xanthohumol obtenido se recoge y seca para obtener xanthohumol con una pureza mayor a 90%.
MX2016004128A 2013-10-04 2014-09-16 Proceso para preparar xanthohumol. MX362188B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PL405540A PL223580B1 (pl) 2013-10-04 2013-10-04 Sposób otrzymywania ksantohumolu o wysokiej czystości
PCT/IB2014/001872 WO2015049561A1 (en) 2013-10-04 2014-09-16 Process for the preparation of xanthohumol

Publications (2)

Publication Number Publication Date
MX2016004128A true MX2016004128A (es) 2016-08-12
MX362188B MX362188B (es) 2019-01-07

Family

ID=51844768

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016004128A MX362188B (es) 2013-10-04 2014-09-16 Proceso para preparar xanthohumol.

Country Status (25)

Country Link
US (1) US9556097B2 (es)
EP (1) EP3052466B1 (es)
JP (1) JP6396479B2 (es)
KR (1) KR102308524B1 (es)
CN (1) CN105829275B (es)
AU (1) AU2014330867B2 (es)
BR (1) BR112016007460B1 (es)
CA (1) CA2926619C (es)
CL (1) CL2016000784A1 (es)
CY (1) CY1119888T1 (es)
DK (1) DK3052466T3 (es)
ES (1) ES2657042T3 (es)
HR (1) HRP20180042T1 (es)
HU (1) HUE037941T2 (es)
IL (1) IL244755B (es)
LT (1) LT3052466T (es)
ME (1) ME02981B (es)
MX (1) MX362188B (es)
PL (1) PL223580B1 (es)
PT (1) PT3052466T (es)
RS (1) RS56756B1 (es)
RU (1) RU2655926C2 (es)
SI (1) SI3052466T1 (es)
UA (1) UA116913C2 (es)
WO (1) WO2015049561A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL242648B1 (pl) * 2017-06-30 2023-04-03 Bioactive Tech Spolka Z Ograniczona Odpowiedzialnoscia Sposób otrzymywania ksantohumolu
US11026897B2 (en) 2018-08-10 2021-06-08 Metagenics, Inc. Composition of curcumagalactomannoside and hops extract
EP4104817A1 (en) 2021-06-17 2022-12-21 Skeye Pharma GbR Ophthalmic composition comprising astragaloside iv
EP4104818A1 (en) 2021-06-17 2022-12-21 Skeye Pharma GbR Ophthalmic composition comprising xanthohumol
EP4302767A1 (en) 2022-07-04 2024-01-10 Skeye Pharma GmbH Ophthalmic composition comprising eriocitrin
PL441690A1 (pl) * 2022-07-08 2024-01-15 Innox Spółka Z Ograniczoną Odpowiedzialnością Sposób izolacji i oczyszczania ksantohumolu

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1274678A (en) 1968-11-19 1972-05-17 Bush Boake Allen Ltd Hop extracts
CN1260122A (zh) * 1999-01-08 2000-07-19 仲伟德 一种以植物为原料的杀菌剂农药
DE19939350B4 (de) 1999-08-19 2005-04-07 Plantextrakt Gmbh & Co. Kg Hopfenextrakt und Verfahren zu dessen Herstellung
DE10139479A1 (de) 2001-08-10 2003-02-27 Schwabe Willmar Gmbh & Co Hopfenextrakte, Verfahren zu ihrer Herstellung und Verwendung
DE10256031A1 (de) 2002-11-30 2004-06-09 Nateco 2 Gmbh & Co. Kg Verfahren zur Herstellung eines Xanthohumol-angereicherten Hopfenextraktes und dessen Verwendung
EP1543834A1 (en) 2003-12-16 2005-06-22 Biodynamics Production of hop extracts having oestrogenic and antiproliferative bioactivity
DE102006018988B3 (de) 2006-04-25 2007-08-09 Nateco2 Gmbh & Co. Kg Verfahren zur Herstellung eines Xanthohumol-haltigen Pulvers hoher Reinheit und dessen Verwendung
RU2344167C2 (ru) * 2007-03-12 2009-01-20 Общество с ограниченной ответственностью "Дары Кубани" Хмелевый экстракт
US8142821B2 (en) 2007-08-15 2012-03-27 Flazan GmbH & Co. KG Xanthohumol-enriched hop extract
CA2696311C (en) * 2007-08-15 2013-07-16 Flaxan Gmbh & Co. Kg Xanthohumol-enriched hop extract
CN101440029A (zh) 2008-11-04 2009-05-27 中国食品发酵工业研究院 一种从啤酒花中提取黄腐酚的方法
CN101433592B (zh) 2008-12-12 2011-06-08 桂林莱茵生物科技股份有限公司 含黄腐酚的啤酒花提取物的制备方法
PL214468B1 (pl) 2009-05-15 2013-08-30 Univ Przyrodniczy We Wroclawiu Sposób otrzymywania ksantohumolu
CN101811950B (zh) 2010-05-07 2013-01-30 玉门拓璞科技开发有限责任公司 高纯度黄腐酚的工业化生产方法

Also Published As

Publication number Publication date
UA116913C2 (uk) 2018-05-25
CN105829275A (zh) 2016-08-03
MX362188B (es) 2019-01-07
CL2016000784A1 (es) 2016-10-07
CN105829275B (zh) 2017-09-19
PL405540A1 (pl) 2015-04-13
EP3052466A1 (en) 2016-08-10
AU2014330867A1 (en) 2016-05-26
PT3052466T (pt) 2018-01-30
RU2655926C2 (ru) 2018-05-30
LT3052466T (lt) 2018-02-12
JP6396479B2 (ja) 2018-09-26
BR112016007460A2 (pt) 2017-08-01
WO2015049561A1 (en) 2015-04-09
IL244755B (en) 2019-10-31
JP2016535763A (ja) 2016-11-17
DK3052466T3 (en) 2018-01-22
SI3052466T1 (en) 2018-02-28
KR102308524B1 (ko) 2021-10-05
KR20160067127A (ko) 2016-06-13
ME02981B (me) 2018-10-20
CA2926619A1 (en) 2015-04-09
PL223580B1 (pl) 2016-10-31
ES2657042T3 (es) 2018-03-01
US20160237014A1 (en) 2016-08-18
EP3052466B1 (en) 2017-10-25
HRP20180042T1 (hr) 2018-02-09
NZ719709A (en) 2020-09-25
US9556097B2 (en) 2017-01-31
IL244755A0 (en) 2016-04-21
AU2014330867B2 (en) 2017-11-23
HUE037941T2 (hu) 2018-09-28
RU2016115081A3 (es) 2018-03-29
RS56756B1 (sr) 2018-04-30
CA2926619C (en) 2021-11-23
RU2016115081A (ru) 2017-11-10
CY1119888T1 (el) 2018-06-27
BR112016007460B1 (pt) 2023-05-02

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