MX2015005341A - Metodos para controlar la presion arterial y para reducir la disnea durante una insuficiencia cardiaca. - Google Patents

Metodos para controlar la presion arterial y para reducir la disnea durante una insuficiencia cardiaca.

Info

Publication number
MX2015005341A
MX2015005341A MX2015005341A MX2015005341A MX2015005341A MX 2015005341 A MX2015005341 A MX 2015005341A MX 2015005341 A MX2015005341 A MX 2015005341A MX 2015005341 A MX2015005341 A MX 2015005341A MX 2015005341 A MX2015005341 A MX 2015005341A
Authority
MX
Mexico
Prior art keywords
blood pressure
methods
heart failure
controlling blood
dyspnea
Prior art date
Application number
MX2015005341A
Other languages
English (en)
Other versions
MX359768B (es
Inventor
Gregory Charles Williams
c jr spindler Edward
M Itri Loretta
Ming-Yi Hu
Original Assignee
Medicines Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicines Co filed Critical Medicines Co
Publication of MX2015005341A publication Critical patent/MX2015005341A/es
Publication of MX359768B publication Critical patent/MX359768B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención divulga métodos para controlar, mantener o reducir la presión arterial y/o para tratar, prevenir o aliviar los síntomas tales como disnea, en un paciente que sufre de o es susceptible a una insuficiencia cardiaca aguda. Los métodos involucran la administración de una cantidad efectiva de una composición farmacéutica que comprende un compuesto de dihidropiridina de acción corta, tal como clevidipina. La composición farmacéutica puede administrarse en una dosis inicial, y si la presión arterial no se controla o se mantiene dentro de un rango objetivo de presión arterial o se reduce dentro de un rango objetivo de presión arterial, la dosis inicial puede ajustarse para conseguir una presión arterial dentro del rango objetivo de presión arterial. El paciente puede tener una presión arterial sistólica de aproximadamente 120 mmHg o más.
MX2015005341A 2012-10-26 2013-10-26 Métodos para controlar la presión arterial y para reducir la disnea durante una insuficiencia cardiaca. MX359768B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261719127P 2012-10-26 2012-10-26
PCT/US2013/066990 WO2014066870A1 (en) 2012-10-26 2013-10-26 Methods for controlling blood pressure and reducing dyspnea in heart failure

Publications (2)

Publication Number Publication Date
MX2015005341A true MX2015005341A (es) 2016-05-24
MX359768B MX359768B (es) 2018-10-10

Family

ID=50545374

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015005341A MX359768B (es) 2012-10-26 2013-10-26 Métodos para controlar la presión arterial y para reducir la disnea durante una insuficiencia cardiaca.

Country Status (18)

Country Link
US (1) US10881645B2 (es)
EP (1) EP2925128B1 (es)
JP (2) JP6329957B2 (es)
KR (1) KR102299073B1 (es)
CN (2) CN104968199A (es)
AU (1) AU2013334081B2 (es)
BR (1) BR112015009291B1 (es)
CA (1) CA2889584C (es)
EA (1) EA030354B1 (es)
ES (1) ES2671639T3 (es)
IL (1) IL238462A0 (es)
MX (1) MX359768B (es)
NZ (1) NZ708511A (es)
PL (1) PL2925128T3 (es)
TR (1) TR201807636T4 (es)
UA (1) UA117571C2 (es)
WO (1) WO2014066870A1 (es)
ZA (1) ZA201503741B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015179334A1 (en) * 2014-05-19 2015-11-26 The Medicines Company Clevidipine nanoparticles and pharmaceutical compositions thereof
SG11202108488SA (en) * 2019-03-05 2021-09-29 Windtree Therapeutics Inc Istaroxime-containing intravenous formulation for the treatment of acute heart failure (ahf)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9303657D0 (sv) 1993-11-05 1993-11-05 Astra Ab Short-acting dihydropyridines
SE9303744D0 (sv) 1993-11-12 1993-11-12 Astra Ab Pharmaceutical emulsion
SE9804002D0 (sv) 1998-11-23 1998-11-23 Astra Ab New manufacturing process
GB2459983B (en) * 2008-05-16 2010-04-28 Corthera Inc Methods of treating dyspnea associated with acute heart failure
KR20170051542A (ko) 2008-08-01 2017-05-11 치에시 파마슈티시 에스.피.아. 약제학적 조성물 및 이를 안정화시키는 방법
CA3108961A1 (en) 2008-08-01 2010-02-04 Hospira, Inc. Pharmaceutical compositions comprising clevidipine and methods for producing low impurity concentrations of the same
CA2778880C (en) * 2009-11-11 2018-02-13 The Medicines Company Methods of treating or preventing stent thrombosis
TW201215392A (en) * 2010-06-16 2012-04-16 Gilead Sciences Inc Use of ranolazine for treating pulmonary hypertension
BR112013008601B1 (pt) * 2010-10-12 2020-03-31 Chiesi Farmaceutici S.P.A. Formulações de emulsão de clevidipina contendo agentes antimicrobianos
RU2623039C2 (ru) 2011-04-01 2017-06-21 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Дигидропиридины (клевидипин) кратковременного действия для применения в восстановлении после инсульта

Also Published As

Publication number Publication date
UA117571C2 (uk) 2018-08-27
TR201807636T4 (tr) 2018-06-21
CA2889584C (en) 2018-08-14
EA030354B1 (ru) 2018-07-31
JP6329957B2 (ja) 2018-05-23
AU2013334081B2 (en) 2017-05-18
US10881645B2 (en) 2021-01-05
KR102299073B1 (ko) 2021-09-09
JP2018065875A (ja) 2018-04-26
WO2014066870A1 (en) 2014-05-01
ZA201503741B (en) 2022-09-28
CN110840890A (zh) 2020-02-28
CA2889584A1 (en) 2014-05-01
EP2925128A4 (en) 2016-06-08
MX359768B (es) 2018-10-10
AU2013334081A1 (en) 2015-06-11
US20140121247A1 (en) 2014-05-01
BR112015009291B1 (pt) 2021-03-16
IL238462A0 (en) 2015-06-30
ES2671639T3 (es) 2018-06-07
NZ708511A (en) 2018-11-30
EP2925128B1 (en) 2018-04-11
PL2925128T3 (pl) 2018-10-31
KR20150104084A (ko) 2015-09-14
EA201590825A1 (ru) 2015-09-30
EP2925128A1 (en) 2015-10-07
JP2015535258A (ja) 2015-12-10
BR112015009291A2 (pt) 2017-07-04
CN104968199A (zh) 2015-10-07

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Owner name: CHIESI FARMACEUTICI S.P.A.

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