MX2013005200A - Derivados de acido hidroxamico y su so en el tratamiento de infecciones bacterianas. - Google Patents
Derivados de acido hidroxamico y su so en el tratamiento de infecciones bacterianas.Info
- Publication number
- MX2013005200A MX2013005200A MX2013005200A MX2013005200A MX2013005200A MX 2013005200 A MX2013005200 A MX 2013005200A MX 2013005200 A MX2013005200 A MX 2013005200A MX 2013005200 A MX2013005200 A MX 2013005200A MX 2013005200 A MX2013005200 A MX 2013005200A
- Authority
- MX
- Mexico
- Prior art keywords
- hydroxymethyl
- methyl
- diinyl
- buta
- hydroxyamino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41231110P | 2010-11-10 | 2010-11-10 | |
| PCT/US2011/059280 WO2012154204A1 (en) | 2010-11-10 | 2011-11-04 | Hydroxamic acid derivatives and their use in the treatment of bacterial infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2013005200A true MX2013005200A (es) | 2013-06-28 |
Family
ID=46317476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013005200A MX2013005200A (es) | 2010-11-10 | 2011-11-04 | Derivados de acido hidroxamico y su so en el tratamiento de infecciones bacterianas. |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP2638006A1 (enExample) |
| JP (1) | JP2014501716A (enExample) |
| KR (1) | KR20140023869A (enExample) |
| CN (1) | CN103298780A (enExample) |
| AR (1) | AR083760A1 (enExample) |
| AU (1) | AU2011367819A1 (enExample) |
| BR (1) | BR112013011693A2 (enExample) |
| CA (1) | CA2817211A1 (enExample) |
| EA (1) | EA201390626A1 (enExample) |
| IL (1) | IL226270A0 (enExample) |
| MX (1) | MX2013005200A (enExample) |
| SG (1) | SG190243A1 (enExample) |
| TW (1) | TW201249786A (enExample) |
| WO (1) | WO2012154204A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2691987C (en) | 2007-06-12 | 2016-08-16 | Achaogen, Inc. | Antibacterial agents |
| EP2847162A1 (en) * | 2012-05-09 | 2015-03-18 | Achaogen, Inc. | Antibacterial agents |
| WO2013170165A1 (en) | 2012-05-10 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| AR097617A1 (es) | 2013-09-13 | 2016-04-06 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos del 2h-indazol |
| KR20160098503A (ko) | 2013-12-19 | 2016-08-18 | 액테리온 파마슈티칼 리미티드 | 항균성 1h-인다졸 및 1h-인돌 유도체 |
| AR099612A1 (es) | 2014-03-04 | 2016-08-03 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona |
| US9539305B1 (en) | 2014-03-14 | 2017-01-10 | Fleurir Abx Llc | Pristinamycin compositions, LpxC compositions, their improvements, and combinations thereof |
| WO2015173329A1 (en) | 2014-05-16 | 2015-11-19 | Actelion Pharmaceuticals Ltd | Antibacterial quinazoline-4(3h)-one derivatives |
| BR112017010474A2 (pt) | 2014-11-19 | 2017-12-26 | Actelion Pharmaceuticals Ltd | derivados antibacterianos de benzotiazol |
| HUE047225T2 (hu) | 2014-12-16 | 2020-04-28 | Novartis Ag | LpxC inhibitor izoxazol hidroxámsav-vegyületek |
| AU2017257755B2 (en) | 2016-04-25 | 2021-05-06 | Duke University | Benzoylglycine derivatives and methods of making and using same |
| SMT202000524T1 (it) | 2016-06-14 | 2020-11-10 | Novartis Ag | Forma cristallina di (r)-4-(5-(ciclopropiletinil)isossazol-3-il)-n-idrossi-2-metil-2-(metilsolfonil)butanammide come agente antibatterico |
| WO2017223349A1 (en) | 2016-06-23 | 2017-12-28 | Achaogen, Inc. | Antibacterial agents |
| KR102868718B1 (ko) * | 2018-02-10 | 2025-10-14 | 케이비피 바이오사이언시즈 씨오., 엘티디. | 항생제로서 작용하는 화합물 |
| CN110563611B (zh) * | 2019-09-19 | 2021-02-02 | 中国医学科学院医药生物技术研究所 | 一种异羟肟酸类衍生物及其制备方法和应用 |
| CN113957098A (zh) * | 2021-09-13 | 2022-01-21 | 湖南工业大学 | 普罗威登斯属细菌菌株在制备二价锰氧化剂中的应用 |
| CN116730870B (zh) | 2023-08-08 | 2023-10-13 | 中国医学科学院医药生物技术研究所 | 异羟肟酸类化合物或其可药用盐、及其用途和制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5925659A (en) | 1996-05-07 | 1999-07-20 | Merck & Co., Inc. | Antibacterial agents |
| WO1998018754A1 (en) | 1996-10-28 | 1998-05-07 | Versicor, Inc. | Methods for solid-phase synthesis of hydroxylamine compounds and derivatives, and combinatorial libraries thereof |
| US6716878B1 (en) | 1999-04-09 | 2004-04-06 | Vernalis (Oxford) Limited | Antimicrobial agents |
| ES2387803T3 (es) * | 2003-01-08 | 2012-10-02 | Novartis Vaccines And Diagnostics, Inc. | Agentes antibacterianos |
| DE102006032709A1 (de) | 2006-07-14 | 2008-01-17 | BSH Bosch und Siemens Hausgeräte GmbH | Luftschallgedämmte Lebensmittelmühle |
| CN101209974A (zh) * | 2006-12-31 | 2008-07-02 | 天津药物研究院 | 异羟肟酸类衍生物及其用途 |
| CA2691987C (en) * | 2007-06-12 | 2016-08-16 | Achaogen, Inc. | Antibacterial agents |
| WO2011005355A1 (en) * | 2009-05-07 | 2011-01-13 | Achaogen, Inc. | Combinations comprising a lpxc inhibitor and an antibiotic for use in the treatment of infections caused by gram-negative bacteria |
| RS59255B1 (sr) * | 2010-04-20 | 2019-10-31 | Fujifilm Toyama Chemical Co Ltd | Derivat hidroksaminske kiseline |
-
2011
- 2011-11-04 EP EP11849908.6A patent/EP2638006A1/en not_active Withdrawn
- 2011-11-04 JP JP2013538794A patent/JP2014501716A/ja active Pending
- 2011-11-04 SG SG2013036272A patent/SG190243A1/en unknown
- 2011-11-04 AU AU2011367819A patent/AU2011367819A1/en not_active Abandoned
- 2011-11-04 WO PCT/US2011/059280 patent/WO2012154204A1/en not_active Ceased
- 2011-11-04 MX MX2013005200A patent/MX2013005200A/es not_active Application Discontinuation
- 2011-11-04 EA EA201390626A patent/EA201390626A1/ru unknown
- 2011-11-04 BR BR112013011693A patent/BR112013011693A2/pt not_active IP Right Cessation
- 2011-11-04 KR KR1020137012799A patent/KR20140023869A/ko not_active Withdrawn
- 2011-11-04 CA CA2817211A patent/CA2817211A1/en not_active Abandoned
- 2011-11-04 TW TW100140449A patent/TW201249786A/zh unknown
- 2011-11-04 AR ARP110104117A patent/AR083760A1/es not_active Application Discontinuation
- 2011-11-04 CN CN2011800639128A patent/CN103298780A/zh active Pending
-
2013
- 2013-05-09 IL IL226270A patent/IL226270A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL226270A0 (en) | 2013-07-31 |
| CN103298780A (zh) | 2013-09-11 |
| EA201390626A1 (ru) | 2013-12-30 |
| KR20140023869A (ko) | 2014-02-27 |
| EP2638006A1 (en) | 2013-09-18 |
| BR112013011693A2 (pt) | 2016-08-09 |
| WO2012154204A1 (en) | 2012-11-15 |
| SG190243A1 (en) | 2013-06-28 |
| AU2011367819A1 (en) | 2013-05-02 |
| AR083760A1 (es) | 2013-03-20 |
| CA2817211A1 (en) | 2012-11-15 |
| TW201249786A (en) | 2012-12-16 |
| JP2014501716A (ja) | 2014-01-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2012154204A1 (en) | Hydroxamic acid derivatives and their use in the treatment of bacterial infections | |
| US9701622B2 (en) | Antibacterial agents | |
| TWI574941B (zh) | 抗菌劑 | |
| JP5550650B2 (ja) | 細菌感染症処置に適用するための有機化合物 | |
| CA2819880C (en) | Substituted 1-benzylcycloalkylcarboxlic acids and use thereof | |
| CA2512582C (en) | Antibacterial agents | |
| WO2014165075A1 (en) | Antibacterial agents | |
| TW201100076A (en) | Substituted aminopropionic derivatives as neprilysin inhibitors | |
| BG107229A (bg) | Циклопентил-заместени глутарамидни производни като инхибитори на неутрална ендопептидаза | |
| US20150175530A1 (en) | Antibacterial agents | |
| JP2017505304A (ja) | １２−ｅｐｉ−プロイロムチリン | |
| KR20180111776A (ko) | 마크로시클릭 광범위 항생제 | |
| US9303027B2 (en) | Kappa opioid receptor agonists | |
| CN103958465B (zh) | 苯基衍生物 | |
| HUE035856T2 (hu) | Fluor-helyettesített (3R,4R,5S)-5-guanidino-4-acilamino-3-(pentán-3-iloxi)ciklohexén-1-karbonsavak, azok észterei és azok alkalmazási módszerei | |
| JP2013534917A (ja) | 自己免疫障害、アレルギー、及び慢性疼痛状態、等の治療に有用な新規カテプシンｓプロテアーゼ阻害剤 | |
| JP2013028536A (ja) | 環状アミン−１−カルボン酸エステル誘導体およびそれを含有する医薬組成物 | |
| JP2794341B2 (ja) | シクロアルキルヒドロキシ尿素類及びそれらのリポキシゲナーゼ阻害物質としての用途 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |