IL226270A0 - History of hydroxamic acid, preparations containing them and their uses - Google Patents
History of hydroxamic acid, preparations containing them and their usesInfo
- Publication number
- IL226270A0 IL226270A0 IL226270A IL22627013A IL226270A0 IL 226270 A0 IL226270 A0 IL 226270A0 IL 226270 A IL226270 A IL 226270A IL 22627013 A IL22627013 A IL 22627013A IL 226270 A0 IL226270 A0 IL 226270A0
- Authority
- IL
- Israel
- Prior art keywords
- compositions
- same
- acid derivatives
- hydroxamic acid
- hydroxamic
- Prior art date
Links
- NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41231110P | 2010-11-10 | 2010-11-10 | |
| PCT/US2011/059280 WO2012154204A1 (en) | 2010-11-10 | 2011-11-04 | Hydroxamic acid derivatives and their use in the treatment of bacterial infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL226270A0 true IL226270A0 (en) | 2013-07-31 |
Family
ID=46317476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL226270A IL226270A0 (en) | 2010-11-10 | 2013-05-09 | History of hydroxamic acid, preparations containing them and their uses |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP2638006A1 (enExample) |
| JP (1) | JP2014501716A (enExample) |
| KR (1) | KR20140023869A (enExample) |
| CN (1) | CN103298780A (enExample) |
| AR (1) | AR083760A1 (enExample) |
| AU (1) | AU2011367819A1 (enExample) |
| BR (1) | BR112013011693A2 (enExample) |
| CA (1) | CA2817211A1 (enExample) |
| EA (1) | EA201390626A1 (enExample) |
| IL (1) | IL226270A0 (enExample) |
| MX (1) | MX2013005200A (enExample) |
| SG (1) | SG190243A1 (enExample) |
| TW (1) | TW201249786A (enExample) |
| WO (1) | WO2012154204A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008154642A2 (en) | 2007-06-12 | 2008-12-18 | Achaogen, Inc. | Antibacterial agents |
| WO2013170030A1 (en) * | 2012-05-09 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| WO2013170165A1 (en) | 2012-05-10 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| AR097617A1 (es) | 2013-09-13 | 2016-04-06 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos del 2h-indazol |
| TR201807881T4 (tr) | 2013-12-19 | 2018-06-21 | Idorsia Pharmaceuticals Ltd | Antibakteriyel 1h-ındazol ve 1h-ındol türevleri. |
| AR099612A1 (es) | 2014-03-04 | 2016-08-03 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona |
| US9539305B1 (en) | 2014-03-14 | 2017-01-10 | Fleurir Abx Llc | Pristinamycin compositions, LpxC compositions, their improvements, and combinations thereof |
| JP2017515906A (ja) | 2014-05-16 | 2017-06-15 | アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ | 抗菌性キナゾロン−４（３ｈ）−オン誘導体 |
| KR20170086079A (ko) | 2014-11-19 | 2017-07-25 | 액테리온 파마슈티칼 리미티드 | 항균성 벤조티아졸 유도체 |
| EA032138B1 (ru) | 2014-12-16 | 2019-04-30 | Новартис Аг | СОЕДИНЕНИЯ ИЗОКСАЗОЛГИДРОКСАМИНОВОЙ КИСЛОТЫ В КАЧЕСТВЕ ИНГИБИТОРОВ LpxC |
| EP3448375B1 (en) | 2016-04-25 | 2023-09-27 | Duke University | Benzoylglycine derivatives and methods of making and using same |
| CA3026356A1 (en) | 2016-06-14 | 2017-12-21 | Novartis Ag | Crystalline form of (r)-4-(5-(cyclopropylethynyl)isoxazol-3-yl)-n-hydroxy-2-methyl-2-(methylsulfonyl)butanamide as an antibacterial agent |
| WO2017223349A1 (en) | 2016-06-23 | 2017-12-28 | Achaogen, Inc. | Antibacterial agents |
| CA3090833A1 (en) * | 2018-02-10 | 2019-08-15 | Kbp Biosciences Co., Ltd. | Compound acting as antibiotics |
| CN110563611B (zh) * | 2019-09-19 | 2021-02-02 | 中国医学科学院医药生物技术研究所 | 一种异羟肟酸类衍生物及其制备方法和应用 |
| CN113957098A (zh) * | 2021-09-13 | 2022-01-21 | 湖南工业大学 | 普罗威登斯属细菌菌株在制备二价锰氧化剂中的应用 |
| CN116730870B (zh) * | 2023-08-08 | 2023-10-13 | 中国医学科学院医药生物技术研究所 | 异羟肟酸类化合物或其可药用盐、及其用途和制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5925659A (en) | 1996-05-07 | 1999-07-20 | Merck & Co., Inc. | Antibacterial agents |
| US6541276B2 (en) | 1996-10-28 | 2003-04-01 | Versicor, Inc. | Methods for solid-phase synthesis of hydroxylamine compounds and derivatives and combinatorial libraries thereof |
| WO2000061134A1 (en) | 1999-04-09 | 2000-10-19 | British Biotech Pharmaceuticals Limited | Antimicrobial agents |
| SG2012000667A (en) * | 2003-01-08 | 2015-03-30 | Univ Washington | Antibacterial agents |
| DE102006032709A1 (de) | 2006-07-14 | 2008-01-17 | BSH Bosch und Siemens Hausgeräte GmbH | Luftschallgedämmte Lebensmittelmühle |
| CN101209974A (zh) * | 2006-12-31 | 2008-07-02 | 天津药物研究院 | 异羟肟酸类衍生物及其用途 |
| WO2008154642A2 (en) * | 2007-06-12 | 2008-12-18 | Achaogen, Inc. | Antibacterial agents |
| WO2011005355A1 (en) * | 2009-05-07 | 2011-01-13 | Achaogen, Inc. | Combinations comprising a lpxc inhibitor and an antibiotic for use in the treatment of infections caused by gram-negative bacteria |
| PH12012502087A1 (en) * | 2010-04-20 | 2015-04-15 | Taisho Pharmaceutical Co Ltd | Novel hydroxamic acid derivative |
-
2011
- 2011-11-04 MX MX2013005200A patent/MX2013005200A/es not_active Application Discontinuation
- 2011-11-04 AR ARP110104117A patent/AR083760A1/es not_active Application Discontinuation
- 2011-11-04 WO PCT/US2011/059280 patent/WO2012154204A1/en not_active Ceased
- 2011-11-04 AU AU2011367819A patent/AU2011367819A1/en not_active Abandoned
- 2011-11-04 CN CN2011800639128A patent/CN103298780A/zh active Pending
- 2011-11-04 BR BR112013011693A patent/BR112013011693A2/pt not_active IP Right Cessation
- 2011-11-04 EA EA201390626A patent/EA201390626A1/ru unknown
- 2011-11-04 SG SG2013036272A patent/SG190243A1/en unknown
- 2011-11-04 TW TW100140449A patent/TW201249786A/zh unknown
- 2011-11-04 EP EP11849908.6A patent/EP2638006A1/en not_active Withdrawn
- 2011-11-04 KR KR1020137012799A patent/KR20140023869A/ko not_active Withdrawn
- 2011-11-04 CA CA2817211A patent/CA2817211A1/en not_active Abandoned
- 2011-11-04 JP JP2013538794A patent/JP2014501716A/ja active Pending
-
2013
- 2013-05-09 IL IL226270A patent/IL226270A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012154204A1 (en) | 2012-11-15 |
| EA201390626A1 (ru) | 2013-12-30 |
| EP2638006A1 (en) | 2013-09-18 |
| AU2011367819A1 (en) | 2013-05-02 |
| AR083760A1 (es) | 2013-03-20 |
| JP2014501716A (ja) | 2014-01-23 |
| MX2013005200A (es) | 2013-06-28 |
| KR20140023869A (ko) | 2014-02-27 |
| CA2817211A1 (en) | 2012-11-15 |
| CN103298780A (zh) | 2013-09-11 |
| TW201249786A (en) | 2012-12-16 |
| SG190243A1 (en) | 2013-06-28 |
| BR112013011693A2 (pt) | 2016-08-09 |
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