MX2013001447A - Metodo de produccion y purificacion de una sialiltransferasa soluble activa. - Google Patents
Metodo de produccion y purificacion de una sialiltransferasa soluble activa.Info
- Publication number
- MX2013001447A MX2013001447A MX2013001447A MX2013001447A MX2013001447A MX 2013001447 A MX2013001447 A MX 2013001447A MX 2013001447 A MX2013001447 A MX 2013001447A MX 2013001447 A MX2013001447 A MX 2013001447A MX 2013001447 A MX2013001447 A MX 2013001447A
- Authority
- MX
- Mexico
- Prior art keywords
- sialyltransferase
- polypeptide
- purifying
- producing
- active soluble
- Prior art date
Links
- 102000003838 Sialyltransferases Human genes 0.000 title abstract 5
- 108090000141 Sialyltransferases Proteins 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 241000699802 Cricetulus griseus Species 0.000 abstract 1
- 102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 abstract 1
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 abstract 1
- OVRNDRQMDRJTHS-CBQIKETKSA-N N-Acetyl-D-Galactosamine Chemical compound CC(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@H](O)[C@@H]1O OVRNDRQMDRJTHS-CBQIKETKSA-N 0.000 abstract 1
- MBLBDJOUHNCFQT-UHFFFAOYSA-N N-acetyl-D-galactosamine Natural products CC(=O)NC(C=O)C(O)C(O)C(O)CO MBLBDJOUHNCFQT-UHFFFAOYSA-N 0.000 abstract 1
- 238000011210 chromatographic step Methods 0.000 abstract 1
- 230000013595 glycosylation Effects 0.000 abstract 1
- 238000006206 glycosylation reaction Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 210000001672 ovary Anatomy 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
- C12Y204/99003—Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (2.4.99.3)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20100171626 EP2415779B1 (en) | 2010-08-02 | 2010-08-02 | Method of producing and purifying an active soluble sialyltransferase |
| PCT/EP2011/063291 WO2012016984A1 (en) | 2010-08-02 | 2011-08-02 | Method of producing and purifying an active soluble sialyltransferase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2013001447A true MX2013001447A (es) | 2013-11-20 |
Family
ID=42736163
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013001447A MX2013001447A (es) | 2010-08-02 | 2011-08-02 | Metodo de produccion y purificacion de una sialiltransferasa soluble activa. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9222081B2 (https=) |
| EP (2) | EP2415779B1 (https=) |
| JP (1) | JP5984267B2 (https=) |
| CN (1) | CN103154017B (https=) |
| CA (1) | CA2807397C (https=) |
| ES (1) | ES2534936T3 (https=) |
| MX (1) | MX2013001447A (https=) |
| PT (1) | PT2415779E (https=) |
| WO (1) | WO2012016984A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013075740A1 (en) * | 2011-11-23 | 2013-05-30 | Sanofi | Antibody purification method |
| KR20150112978A (ko) * | 2013-02-06 | 2015-10-07 | 에이전시 포 사이언스, 테크놀로지 앤드 리서치 | 단백질 제제 내의 응집체 함량을 감소시키기 위한 혼합 다관능 금속 친화성 표면들 |
| EP3301115B1 (en) | 2013-05-06 | 2021-11-10 | Sanofi | Continuous multistep process for purifying antibodies |
| BR112017021016A2 (pt) * | 2015-03-31 | 2018-07-03 | Yeda Research And Development Co Ltd | preparação de proteína, composição farmacêutica, proteína de fusão, polinucleotídeo isolado, estrutura de ácido nucleico, método para tratamento de doença ou condição associada ao excesso de glutamato, e método de purificação de um polipeptídeo |
| KR101667677B1 (ko) * | 2015-05-29 | 2016-10-19 | 한국생명공학연구원 | 재조합 ST6Gal1 단백질을 활성형으로 제조하는 방법 |
| CN117887794A (zh) | 2016-12-21 | 2024-04-16 | 豪夫迈·罗氏有限公司 | 用于体外糖工程化抗体的方法 |
| JP6931058B2 (ja) * | 2016-12-21 | 2021-09-01 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 抗体のインビトロ糖鎖工学における酵素の再使用 |
| IL272987B (en) | 2017-09-04 | 2022-08-01 | 89Bio Ltd | fgf-21 mutant peptide conjugates and uses thereof |
| WO2019063849A1 (en) * | 2017-12-20 | 2019-04-04 | Dsm Ip Assets B.V. | PURIFICATION OF A POLYPEPTIDE OF INTEREST |
| KR102362777B1 (ko) * | 2018-03-27 | 2022-02-15 | 주식회사 녹십자 | 친화성 크로마토그래피 공정을 포함하는 백일해균 유래 단백질 수득 방법 |
| EP3546475A1 (en) | 2018-03-27 | 2019-10-02 | Sanofi | Full flow-through process for purifying recombinant proteins |
| KR102140531B1 (ko) * | 2018-08-07 | 2020-08-04 | (주)휴온스 | Gly-Tβ4의 제조방법 |
| DK3613486T3 (da) * | 2018-08-24 | 2021-01-04 | Uga Biopharma Gmbh | Metode og anlæg til rengøring af epo og/eller et epo-derivat |
| CN113416243B (zh) * | 2021-08-23 | 2021-12-10 | 上海盛迪医药有限公司 | 一种纯化抗体的方法 |
| CN119912505A (zh) * | 2025-04-02 | 2025-05-02 | 浙江熙正霖生物科技有限公司 | 一种从发酵液中提纯唾液酸的方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5032519A (en) * | 1989-10-24 | 1991-07-16 | The Regents Of The Univ. Of California | Method for producing secretable glycosyltransferases and other Golgi processing enzymes |
| WO1995018217A1 (en) | 1993-12-24 | 1995-07-06 | The Institute Of Physical And Chemical Research | Novel sugar-chain synthetase and process for producing the same |
| US6280989B1 (en) * | 1999-06-17 | 2001-08-28 | Dmitri Kapitonov | Sialyltransferases |
| ES2411007T3 (es) | 2001-10-10 | 2013-07-04 | Novo Nordisk A/S | Remodelación y glicoconjugación de péptidos |
| CN1897812B (zh) * | 2003-12-03 | 2011-08-17 | 生物种属学股份公司 | 糖聚乙二醇化的粒细胞集落刺激因子 |
| EP1765993A4 (en) | 2004-06-03 | 2008-08-20 | Neose Technologies Inc | ST6GALNACL TRUNC POLYPEPTIDES AND NUCLEIC ACIDS |
| US20100143969A1 (en) | 2005-03-24 | 2010-06-10 | Neose Technologies, Inc. | Expression of soluble, active eukaryotic glycosyltransferases in prokaryotic organisms |
| JP2008538181A (ja) * | 2005-03-30 | 2008-10-16 | ネオス テクノロジーズ インコーポレイテッド | 昆虫細胞系において増殖させたペプチドを生産するための製造方法 |
| US20090047710A1 (en) | 2005-11-09 | 2009-02-19 | Neose Technologies, Inc. | ST3Gal-1/ST6GalNAc-1 Chimeras |
| EP2054521A4 (en) * | 2006-10-03 | 2012-12-19 | Novo Nordisk As | PROCESS FOR CLEANING POLYPEPTIDE CONJUGATES |
| US20080207487A1 (en) | 2006-11-02 | 2008-08-28 | Neose Technologies, Inc. | Manufacturing process for the production of polypeptides expressed in insect cell-lines |
-
2010
- 2010-08-02 EP EP20100171626 patent/EP2415779B1/en active Active
- 2010-08-02 ES ES10171626.4T patent/ES2534936T3/es active Active
- 2010-08-02 PT PT101716264T patent/PT2415779E/pt unknown
-
2011
- 2011-08-02 CA CA2807397A patent/CA2807397C/en active Active
- 2011-08-02 WO PCT/EP2011/063291 patent/WO2012016984A1/en not_active Ceased
- 2011-08-02 JP JP2013522234A patent/JP5984267B2/ja active Active
- 2011-08-02 US US13/813,804 patent/US9222081B2/en active Active
- 2011-08-02 MX MX2013001447A patent/MX2013001447A/es unknown
- 2011-08-02 EP EP11738247.3A patent/EP2601207B1/en active Active
- 2011-08-02 CN CN201180047627.7A patent/CN103154017B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US9222081B2 (en) | 2015-12-29 |
| JP2013535207A (ja) | 2013-09-12 |
| WO2012016984A1 (en) | 2012-02-09 |
| PT2415779E (pt) | 2015-05-13 |
| CN103154017B (zh) | 2016-02-03 |
| JP5984267B2 (ja) | 2016-09-06 |
| CA2807397C (en) | 2019-03-19 |
| US20140057316A1 (en) | 2014-02-27 |
| CA2807397A1 (en) | 2012-02-09 |
| EP2415779A1 (en) | 2012-02-08 |
| EP2601207A1 (en) | 2013-06-12 |
| CN103154017A (zh) | 2013-06-12 |
| EP2601207B1 (en) | 2016-12-28 |
| ES2534936T3 (es) | 2015-04-30 |
| EP2415779B1 (en) | 2015-01-21 |
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