MX2011012196A - Composiciones y metodos para el suministro de farmaco. - Google Patents

Composiciones y metodos para el suministro de farmaco.

Info

Publication number
MX2011012196A
MX2011012196A MX2011012196A MX2011012196A MX2011012196A MX 2011012196 A MX2011012196 A MX 2011012196A MX 2011012196 A MX2011012196 A MX 2011012196A MX 2011012196 A MX2011012196 A MX 2011012196A MX 2011012196 A MX2011012196 A MX 2011012196A
Authority
MX
Mexico
Prior art keywords
methods
compositions
drug delivery
particle core
particle
Prior art date
Application number
MX2011012196A
Other languages
English (en)
Inventor
Jane Werling
Shawn F Bairstow
Barrett Rabinow
Mahesh V Chaubal
Sarah Lee
Original Assignee
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int filed Critical Baxter Int
Publication of MX2011012196A publication Critical patent/MX2011012196A/es

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
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    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
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    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
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    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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Abstract

La presente invención está dirigida a partículas de superficie modificada y a métodos para hacer y utilizar las mismas. Las partículas de superficie modificada comprenden un núcleo de partícula y un revestimiento asociado con el núcleo de partícula, en donde el núcleo de partícula comprende un agente activo, el revestimiento comprende un agente tensoactivo que tienen la fórmula (I) o una sal del mismo, y la partícula de superficie modificada tiene un tamaño promedio de aproximadamente 1 nm a aproximadamente 2,000 nm.
MX2011012196A 2009-05-15 2010-05-13 Composiciones y metodos para el suministro de farmaco. MX2011012196A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/467,230 US10952965B2 (en) 2009-05-15 2009-05-15 Compositions and methods for drug delivery
PCT/US2010/034711 WO2010132664A1 (en) 2009-05-15 2010-05-13 Compositions and methods for drug delivery

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Publication Number Publication Date
MX2011012196A true MX2011012196A (es) 2013-05-30

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US (2) US10952965B2 (es)
EP (1) EP2429493B1 (es)
JP (1) JP5668055B2 (es)
KR (1) KR101722794B1 (es)
CN (1) CN102458369B (es)
AU (1) AU2010249008B2 (es)
BR (1) BRPI1010903A2 (es)
CA (1) CA2761801C (es)
ES (1) ES2509919T3 (es)
HK (1) HK1170679A1 (es)
IL (1) IL216374A (es)
MX (1) MX2011012196A (es)
SG (1) SG176055A1 (es)
WO (1) WO2010132664A1 (es)

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US8653131B2 (en) 2008-08-22 2014-02-18 Baxter Healthcare S.A. Polymeric benzyl carbonate-derivatives
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