MX2010008899A - Procedimiento para la sintesis regioselectiva de derivados de acido 1-alquil-3-haloalquil-pirazol-4-carboxilico. - Google Patents

Procedimiento para la sintesis regioselectiva de derivados de acido 1-alquil-3-haloalquil-pirazol-4-carboxilico.

Info

Publication number
MX2010008899A
MX2010008899A MX2010008899A MX2010008899A MX2010008899A MX 2010008899 A MX2010008899 A MX 2010008899A MX 2010008899 A MX2010008899 A MX 2010008899A MX 2010008899 A MX2010008899 A MX 2010008899A MX 2010008899 A MX2010008899 A MX 2010008899A
Authority
MX
Mexico
Prior art keywords
acid derivatives
alkyl
carboxylic acid
haloalkylpy
razole
Prior art date
Application number
MX2010008899A
Other languages
English (en)
Inventor
Sergii Pazenok
Norbert Lui
Arnd Neeff
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of MX2010008899A publication Critical patent/MX2010008899A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Abstract

La presente invención se refiere a un procedimiento para la Síntesis regioselectiva de derivados de ácido 1-alquil-3-haloalquil-pirazol-4-carboxílico por ciclación de derivados de ácido acrílico 2,3-disustituidos con hidracinas en presencia de compuestos carbonílicos.
MX2010008899A 2008-03-10 2009-02-26 Procedimiento para la sintesis regioselectiva de derivados de acido 1-alquil-3-haloalquil-pirazol-4-carboxilico. MX2010008899A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08152532A EP2100883A1 (de) 2008-03-10 2008-03-10 Verfahren zur regioselektiven Synthese von 1-Alkyl-3-haloalkyl-pyrazol-4carbonsäure-Derivaten
PCT/EP2009/001354 WO2009112157A1 (de) 2008-03-10 2009-02-26 Verfahren zur regioselektiven synthese von l-alkvl-3-haloalkyl-pvrazol-4-carbonsäure-derivaten

Publications (1)

Publication Number Publication Date
MX2010008899A true MX2010008899A (es) 2010-10-25

Family

ID=39587595

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010008899A MX2010008899A (es) 2008-03-10 2009-02-26 Procedimiento para la sintesis regioselectiva de derivados de acido 1-alquil-3-haloalquil-pirazol-4-carboxilico.

Country Status (16)

Country Link
US (1) US8350053B2 (es)
EP (2) EP2100883A1 (es)
JP (1) JP5503562B2 (es)
KR (1) KR101652916B1 (es)
CN (1) CN101970412B (es)
BR (1) BRPI0909655B1 (es)
CA (1) CA2717805C (es)
DK (1) DK2257532T3 (es)
ES (1) ES2425972T3 (es)
IL (1) IL207487A (es)
MX (1) MX2010008899A (es)
MY (1) MY155478A (es)
PL (1) PL2257532T3 (es)
RU (1) RU2498978C2 (es)
TW (1) TWI440629B (es)
WO (1) WO2009112157A1 (es)

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EP2181087B1 (en) 2007-08-16 2015-10-14 Solvay Sa Process for the preparation of esters of 4-fluorosubstituted 3-oxo-alcanoic acids
EP2133341A1 (de) * 2008-02-25 2009-12-16 Bayer CropScience AG Verfahren zur regioselektiven Synthese von 1-Alkyl-3-haloalkyl-pyrazol-4-carbonsäure-Derivaten
WO2012025469A1 (en) * 2010-08-24 2012-03-01 Solvay Sa Improved process for the preparation of esters of 1-h-pyrazole-4-carboxylic acids
EP2623496A1 (de) 2012-02-01 2013-08-07 Bayer CropScience AG Verfahren zur Herstellung von 3,5-bis (fluoralkyl)-pyrazol-4-carbonsäure-Derivaten und 3,5-bis(fluoralkyl)-pyrazolen
EP2644593A1 (en) * 2012-03-30 2013-10-02 Solvay Sa Dialkoxymethyl oxobutyric acid esters, their manufacture and use
CN102702104B (zh) * 2012-06-08 2015-02-25 巨化集团公司 一种3-二氟甲基-1-甲基吡唑-4-甲酸乙酯的连续化合成方法
US8871947B2 (en) 2013-02-04 2014-10-28 KingChem LLC Preparation of alkyl 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid ester
BR112015028751B1 (pt) * 2013-05-22 2021-01-12 Bayer Cropscience Aktiengesellschaft Processo para a preparação de derivados de 3,5-bis (fluoralquil)pirazol a partir de alfa, alfa-dihaloaminas e uso destes para preparação de ingredientes fungicidas ativos
JP6518654B2 (ja) 2013-05-22 2019-05-22 バイエル・クロップサイエンス・アクチェンゲゼルシャフト ３，５−ビス（フルオロアルキル）ピラゾール誘導体の製造方法
CN103360313A (zh) * 2013-07-12 2013-10-23 雅本化学股份有限公司 3-氟代烷基-1-取代吡唑-4-羧酸及其制备方法
TWI647215B (zh) * 2013-11-11 2019-01-11 德商拜耳作物科學股份有限公司 自α,α－二鹵胺製備３,５－雙鹵烷基吡唑衍生物之方法
US9139507B2 (en) 2013-12-09 2015-09-22 KingChem LLC. Process for the preparation of alkyl 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylate and its analogs
ES2663614T3 (es) 2014-03-24 2018-04-16 Bayer Cropscience Aktiengesellschaft Procedimiento de preparación de derivados de 3,5-bis(haloalquil)pirazol a partir de alfa, alfa-dihaloaminas y cetiminas
EP3015458A1 (en) 2014-11-03 2016-05-04 Bayer CropScience AG Process for preparing 3,5-bis(haloalkyl)pyrazole derivatives from a,a-dihaloamines and ketimines
WO2015155713A1 (en) * 2014-04-09 2015-10-15 Isagro S.P.A. Process for the regioselective synthesis of 1,3, 4 -substituted pyrazoles
US9914704B2 (en) 2014-06-11 2018-03-13 Bayer Cropscience Aktiengesellschaft Process for preparing 3,5-bis(haloalkyl)pyrazoles via acylation of ketimines
KR102430611B1 (ko) 2014-06-11 2022-08-08 바이엘 크롭사이언스 악티엔게젤샤프트 히드라존의 아실화를 통한 3,5-비스(할로알킬)피라졸 유도체의 제조 방법
CN105541716B (zh) 2015-03-26 2024-02-23 Ａｇｃ株式会社 吡唑衍生物的制造方法
JP2018520142A (ja) 2015-06-26 2018-07-26 バイエル・クロップサイエンス・アクチェンゲゼルシャフト α，α−ジハロアルキルアミンとケチミンからハロアルコキシ基及びハロアルキルチオ基を含んでいる置換ピラゾール類を調製する方法
CN106467492B (zh) * 2015-08-14 2019-12-17 联化科技(盐城)有限公司 多氟甲基吡唑类化合物的制备方法、中间体及制备方法
WO2018054807A1 (en) 2016-09-21 2018-03-29 Bayer Cropscience Aktiengesellschaft Process for preparing 3-fluoroalkyl-5-pyrazolecarboxylates and 3-fluoroalkyl-5-pyrazolecarboxylic acids
KR20210011922A (ko) * 2018-05-21 2021-02-02 피아이 인더스트리스 엘티디. 치환된 헤테로사이클릭 화합물의 제조 방법

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KR20020058089A (ko) * 1999-12-09 2002-07-12 릴리 엠 씨즐러 스피허, 아네뜨 워너 살진균제로서의 피라졸카복스아미드 및 피라졸티오아미드
JP4448327B2 (ja) * 2001-08-13 2010-04-07 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 新規置換１ｈ−ジヒドロピラゾール、それらの製造および使用
DE10215292A1 (de) * 2002-02-19 2003-08-28 Bayer Cropscience Ag Disubstitutierte Pyrazolylcarbocanilide
DE10349500A1 (de) 2003-10-23 2005-06-02 Bayer Cropscience Ag Verfahren zum Herstellen von 2-Dihalogenacyl-3-amino-acrylsäureestern und 3-Dihalogenmethyl-pyrazol-4-carbonsäureestern
WO2005123690A1 (de) * 2004-06-18 2005-12-29 Basf Aktiengesellschaft 1-methyl-3-difluormethyl-pyrazol-4-carbonsäure-(ortho-phenyl)-anilide und ihre verwendung als fungizid
WO2006090778A1 (ja) 2005-02-25 2006-08-31 Sagami Chemical Research Center １－置換－３－フルオロアルキルピラゾール－４－カルボン酸エステルの製造方法
DE102006039909A1 (de) * 2006-08-25 2008-03-13 Bayer Cropscience Ag Verfahren zum Herstellen von 3-Dihalomethyl-pyrazol-4-carbonsäurederivaten
ES2338281T3 (es) * 2006-11-03 2010-05-05 Basf Se Metodo para la elaboracion de carboxilatos de difluormetilpirazolilo.
EP2133341A1 (de) * 2008-02-25 2009-12-16 Bayer CropScience AG Verfahren zur regioselektiven Synthese von 1-Alkyl-3-haloalkyl-pyrazol-4-carbonsäure-Derivaten

Also Published As

Publication number Publication date
WO2009112157A1 (de) 2009-09-17
EP2257532B1 (de) 2013-05-29
CA2717805A1 (en) 2009-09-17
RU2498978C2 (ru) 2013-11-20
CA2717805C (en) 2016-02-23
DK2257532T3 (da) 2013-09-08
ES2425972T3 (es) 2013-10-18
CN101970412B (zh) 2013-06-26
TWI440629B (zh) 2014-06-11
BRPI0909655A2 (pt) 2015-08-04
EP2257532A1 (de) 2010-12-08
US20110028735A1 (en) 2011-02-03
MY155478A (en) 2015-10-30
IL207487A (en) 2014-06-30
JP2011513446A (ja) 2011-04-28
PL2257532T3 (pl) 2013-11-29
US8350053B2 (en) 2013-01-08
CN101970412A (zh) 2011-02-09
KR20100137443A (ko) 2010-12-30
KR101652916B1 (ko) 2016-08-31
JP5503562B2 (ja) 2014-05-28
EP2100883A1 (de) 2009-09-16
RU2010141358A (ru) 2012-04-20
TW200951113A (en) 2009-12-16
BRPI0909655B1 (pt) 2018-06-05
IL207487A0 (en) 2010-12-30

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