MX2010007586A - Inhibidores terapeuticos de la funcion del inhibidor del activador de plasminogeno 1 y metodos de uso. - Google Patents
Inhibidores terapeuticos de la funcion del inhibidor del activador de plasminogeno 1 y metodos de uso.Info
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- MX2010007586A MX2010007586A MX2010007586A MX2010007586A MX2010007586A MX 2010007586 A MX2010007586 A MX 2010007586A MX 2010007586 A MX2010007586 A MX 2010007586A MX 2010007586 A MX2010007586 A MX 2010007586A MX 2010007586 A MX2010007586 A MX 2010007586A
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- C12N9/2405—Glucanases
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
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- C12Y304/21—Serine endopeptidases (3.4.21)
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| WO2009089059A2 (en) | 2008-01-09 | 2009-07-16 | Intrexon Corporation | Therapeutic inhibitors of pai-1 function methods of their use |
| WO2011143499A1 (en) * | 2010-05-12 | 2011-11-17 | Tengion, Inc. | Bioactive renal cells |
| WO2013164970A1 (ja) | 2012-05-01 | 2013-11-07 | 富士フイルム株式会社 | 多能性幹細胞の培養方法及びこれに用いるポリペプチド |
| CN103421781B (zh) * | 2012-07-04 | 2014-12-31 | 华中农业大学 | 猪肌肉组织特异性表达基因myf6启动子及应用 |
| WO2015086548A1 (en) * | 2013-12-10 | 2015-06-18 | F. Hoffmann-La Roche Ag | Use of the binding domain of a subunit of a multi-subunit structure for targeted delivery of pharmaceutically active entities to the multi-subunit structure |
| WO2018108161A1 (zh) | 2016-12-15 | 2018-06-21 | 深圳瑞健生命科学研究院有限公司 | 一种预防和治疗肥胖症的方法和药物 |
| US11389515B2 (en) | 2016-12-15 | 2022-07-19 | Talengen International Limited | Method for mitigating heart disease |
| TW201822809A (zh) | 2016-12-15 | 2018-07-01 | 深圳瑞健生命科學硏究院有限公司 | 一種預防和治療高脂血症的方法 |
| US11613744B2 (en) | 2018-12-28 | 2023-03-28 | Vertex Pharmaceuticals Incorporated | Modified urokinase-type plasminogen activator polypeptides and methods of use |
| EP3902913A1 (en) | 2018-12-28 | 2021-11-03 | Catalyst Biosciences, Inc. | Modified urokinase-type plasminogen activator polypeptides and methods of use |
| CN119656313A (zh) * | 2024-12-13 | 2025-03-21 | 四川大学华西医院 | Serpine1基因作为靶点在制备预防或治疗心肌纤维化药物中的用途 |
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| AU1191001A (en) * | 1999-10-07 | 2001-05-10 | Human Genome Sciences, Inc. | Plasminogen-like polynucleotides, polypeptides, and antibodies |
| DE10053251A1 (de) * | 2000-10-26 | 2002-05-08 | Boehringer Ingelheim Pharma | Epitope von PAI-1 |
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| US7241613B1 (en) * | 2002-06-05 | 2007-07-10 | Oscient Pharmaceuticals Corporation | Identification of Candida cell surface proteins and their uses |
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| CA2509222A1 (en) * | 2002-12-10 | 2004-06-24 | Wyeth | Substituted indole oxo-acetyl amino acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (pai-1) |
| AU2005248371B2 (en) | 2004-05-18 | 2011-12-15 | Intrexon Corporation | Methods for dynamic vector assembly of DNA cloning vector plasmids |
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| WO2009014564A2 (en) | 2007-04-27 | 2009-01-29 | The University Of Toledo | Modified plasminogen activator inhibitor type-1 molecule and methods based thereon |
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| US20110055940A1 (en) | 2011-03-03 |
| AU2009204464A1 (en) | 2009-07-16 |
| EP2242501A4 (en) | 2011-10-19 |
| EP2242501A2 (en) | 2010-10-27 |
| US20130267022A1 (en) | 2013-10-10 |
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| JP2012135307A (ja) | 2012-07-19 |
| CN102123721A (zh) | 2011-07-13 |
| US8828686B2 (en) | 2014-09-09 |
| AU2009204464B2 (en) | 2014-12-04 |
| WO2009089059A3 (en) | 2009-09-24 |
| US8431363B2 (en) | 2013-04-30 |
| KR101712208B1 (ko) | 2017-03-03 |
| BRPI0906867A2 (pt) | 2019-09-24 |
| CA2711878A1 (en) | 2009-07-16 |
| IL206891A0 (en) | 2010-12-30 |
| KR20100129271A (ko) | 2010-12-08 |
| RU2010133847A (ru) | 2012-05-20 |
| WO2009089059A2 (en) | 2009-07-16 |
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