MX2009012773A - Ribointerruptores y metodos y composiciones para usarse de y con ribointerruptores. - Google Patents

Ribointerruptores y metodos y composiciones para usarse de y con ribointerruptores.

Info

Publication number
MX2009012773A
MX2009012773A MX2009012773A MX2009012773A MX2009012773A MX 2009012773 A MX2009012773 A MX 2009012773A MX 2009012773 A MX2009012773 A MX 2009012773A MX 2009012773 A MX2009012773 A MX 2009012773A MX 2009012773 A MX2009012773 A MX 2009012773A
Authority
MX
Mexico
Prior art keywords
riboswitches
portions
methods
compositions
variety
Prior art date
Application number
MX2009012773A
Other languages
English (en)
Inventor
Ronald R Breaker
Narasimhan Sudarsan
Zasha Weinberg
Joy Xin Wang
Michelle M Meyer
Adam Roth
Elizabeth E Regulski
Original Assignee
Univ Yale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Yale filed Critical Univ Yale
Publication of MX2009012773A publication Critical patent/MX2009012773A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease

Abstract

Los ribointerruptores son blancos para antibióticos y otras terapias de moléculas pequeñas. Los ribointerruptores y porciones de los mismos pueden utilizarse para regular la expresión o función de las moléculas de ARN y otros elementos y moléculas. Los ribointerruptores y porciones de los mismos pueden usarse en una variedad de otros métodos para, por ejemplo, identificar o detectar compuestos. Los compuestos se pueden usar para estimular, activar, inhibir y/o inactivar el ribointerruptor. Los ribointerruptores y porciones de los mismos, solos y en combinación unos con otros ácidos nucléicos, pueden usarse en una variedad de construcciones y moléculas de ARN y pueden codificarse por ácidos nucléicos.
MX2009012773A 2007-05-29 2008-05-29 Ribointerruptores y metodos y composiciones para usarse de y con ribointerruptores. MX2009012773A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93211207P 2007-05-29 2007-05-29
PCT/US2008/065179 WO2008156987A2 (en) 2007-05-29 2008-05-29 Riboswitches and methods and compositions for use of and with riboswitches

Publications (1)

Publication Number Publication Date
MX2009012773A true MX2009012773A (es) 2009-12-16

Family

ID=40156887

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009012773A MX2009012773A (es) 2007-05-29 2008-05-29 Ribointerruptores y metodos y composiciones para usarse de y con ribointerruptores.

Country Status (10)

Country Link
US (1) US20100286082A1 (es)
EP (3) EP2426218A1 (es)
JP (1) JP2010528617A (es)
KR (1) KR20100017905A (es)
CN (1) CN101849020A (es)
AU (1) AU2008266684A1 (es)
CA (1) CA2688575A1 (es)
MX (1) MX2009012773A (es)
SG (2) SG174103A1 (es)
WO (1) WO2008156987A2 (es)

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CN110184326B (zh) * 2019-05-13 2022-07-01 华侨大学 一种tpp核糖开关序列引物和肠道菌群分类方法
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KR102563799B1 (ko) 2020-06-01 2023-08-03 에이-알파 바이오, 인크. 단백질-단백질 상호작용 특징화 및 조작 방법
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WO2008156987A3 (en) 2009-05-07
CN101849020A (zh) 2010-09-29
EP2164996A2 (en) 2010-03-24
KR20100017905A (ko) 2010-02-16
EP2426218A1 (en) 2012-03-07
CA2688575A1 (en) 2008-12-24
AU2008266684A2 (en) 2010-01-07
SG174104A1 (en) 2011-09-29
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AU2008266684A1 (en) 2008-12-24
EP2164996A4 (en) 2010-07-14

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