MX2009004943A - Inhibidores del virus de la hepatitis c. - Google Patents
Inhibidores del virus de la hepatitis c.Info
- Publication number
- MX2009004943A MX2009004943A MX2009004943A MX2009004943A MX2009004943A MX 2009004943 A MX2009004943 A MX 2009004943A MX 2009004943 A MX2009004943 A MX 2009004943A MX 2009004943 A MX2009004943 A MX 2009004943A MX 2009004943 A MX2009004943 A MX 2009004943A
- Authority
- MX
- Mexico
- Prior art keywords
- hepatitis
- virus inhibitors
- compounds
- disclosed
- virus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
Abstract
Se describen inhibidores del virus de Hepatitis C que tienen la fórmula general (ver fórmula (I)) También se describen composiciones que comprenden los compuestos y métodos de uso de los compuestos para inhibir el VHC:.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86613006P | 2006-11-16 | 2006-11-16 | |
US11/939,780 US7888464B2 (en) | 2006-11-16 | 2007-11-14 | Hepatitis C virus inhibitors |
PCT/US2007/084799 WO2008064066A1 (en) | 2006-11-16 | 2007-11-15 | Hepatitis c virus inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009004943A true MX2009004943A (es) | 2009-05-19 |
Family
ID=39247306
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009004943A MX2009004943A (es) | 2006-11-16 | 2007-11-15 | Inhibidores del virus de la hepatitis c. |
Country Status (17)
Country | Link |
---|---|
US (1) | US7888464B2 (es) |
EP (1) | EP2086995B1 (es) |
JP (1) | JP5241729B2 (es) |
KR (1) | KR20090083462A (es) |
AT (1) | ATE546460T1 (es) |
AU (1) | AU2007323793A1 (es) |
BR (1) | BRPI0719008A2 (es) |
CA (1) | CA2669856A1 (es) |
CO (1) | CO6190510A2 (es) |
EA (1) | EA015827B1 (es) |
ES (1) | ES2381308T3 (es) |
HK (1) | HK1128131A1 (es) |
IL (1) | IL198741A0 (es) |
MX (1) | MX2009004943A (es) |
NO (1) | NO20091871L (es) |
NZ (1) | NZ576814A (es) |
WO (1) | WO2008064066A1 (es) |
Families Citing this family (37)
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EP2245015A4 (en) * | 2008-01-24 | 2012-05-30 | Enanta Pharm Inc | DIFLUORATED TRIPEPTIDES AS INHIBITORS OF HCV SERINE PROTEASE |
US8372802B2 (en) * | 2008-03-20 | 2013-02-12 | Enanta Pharmaceuticals, Inc. | Fluorinated macrocyclic compounds as hepatitis C virus inhibitors |
US8207341B2 (en) | 2008-09-04 | 2012-06-26 | Bristol-Myers Squibb Company | Process or synthesizing substituted isoquinolines |
UY32099A (es) | 2008-09-11 | 2010-04-30 | Enanta Pharm Inc | Inhibidores macrocíclicos de serina proteasas de hepatitis c |
US8044087B2 (en) * | 2008-09-29 | 2011-10-25 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US8563505B2 (en) * | 2008-09-29 | 2013-10-22 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US20100272674A1 (en) * | 2008-12-04 | 2010-10-28 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
US8283310B2 (en) * | 2008-12-15 | 2012-10-09 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
JP2012523419A (ja) | 2009-04-08 | 2012-10-04 | イデニク プハルマセウティカルス,インコーポレイテッド | 大環状セリンプロテアーゼ阻害剤 |
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JP2012532146A (ja) * | 2009-07-02 | 2012-12-13 | ドクター・レディーズ・ラボラトリーズ・リミテッド | アミノビニルシクロプロパンカルボン酸誘導体の分割のための酵素および方法 |
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JP5568137B2 (ja) * | 2010-09-22 | 2014-08-06 | 三井化学アグロ株式会社 | 含フッ素カルバマート基を有するアミノ酸アミド誘導体の製造方法、その製造中間体、及びエチレンジアミン誘導体の製造方法 |
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WO2013190509A2 (en) * | 2012-06-22 | 2013-12-27 | Dr.Reddys Laboratories Limited | Preparation of intermediates of boceprevir |
UA119315C2 (uk) | 2012-07-03 | 2019-06-10 | Гіліад Фармассет Елелсі | Інгібітори вірусу гепатиту с |
BR112015007879A2 (pt) | 2012-10-19 | 2017-07-04 | Bristol Myers Squibb Co | inibidores do vírus da hepatite c |
US9334279B2 (en) | 2012-11-02 | 2016-05-10 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
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JO2768B1 (en) | 2005-07-29 | 2014-03-15 | تيبوتيك فارماسيوتيكالز ليمتد | Large cyclic inhibitors of hepatitis C virus |
AR055361A1 (es) | 2005-07-29 | 2007-08-22 | Medivir Ab | Inhibidores macrociclicos del virus de la hepatitis c |
PL1919904T3 (pl) | 2005-07-29 | 2014-06-30 | Janssen R&D Ireland | Makrocykliczne inhibitory wirusa zapalenia wątroby typu C |
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-
2007
- 2007-11-14 US US11/939,780 patent/US7888464B2/en active Active
- 2007-11-15 CA CA002669856A patent/CA2669856A1/en not_active Abandoned
- 2007-11-15 MX MX2009004943A patent/MX2009004943A/es active IP Right Grant
- 2007-11-15 JP JP2009537359A patent/JP5241729B2/ja not_active Expired - Fee Related
- 2007-11-15 EA EA200900697A patent/EA015827B1/ru not_active IP Right Cessation
- 2007-11-15 BR BRPI0719008-5A2A patent/BRPI0719008A2/pt not_active IP Right Cessation
- 2007-11-15 AU AU2007323793A patent/AU2007323793A1/en not_active Abandoned
- 2007-11-15 KR KR1020097012336A patent/KR20090083462A/ko not_active Application Discontinuation
- 2007-11-15 EP EP07864446A patent/EP2086995B1/en active Active
- 2007-11-15 WO PCT/US2007/084799 patent/WO2008064066A1/en active Application Filing
- 2007-11-15 AT AT07864446T patent/ATE546460T1/de active
- 2007-11-15 ES ES07864446T patent/ES2381308T3/es active Active
- 2007-11-15 NZ NZ576814A patent/NZ576814A/en not_active IP Right Cessation
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2009
- 2009-05-13 NO NO20091871A patent/NO20091871L/no not_active Application Discontinuation
- 2009-05-14 IL IL198741A patent/IL198741A0/en unknown
- 2009-05-15 CO CO09049882A patent/CO6190510A2/es not_active Application Discontinuation
- 2009-08-31 HK HK09107945.2A patent/HK1128131A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ES2381308T3 (es) | 2012-05-25 |
WO2008064066A1 (en) | 2008-05-29 |
US7888464B2 (en) | 2011-02-15 |
JP2010510234A (ja) | 2010-04-02 |
KR20090083462A (ko) | 2009-08-03 |
EP2086995A1 (en) | 2009-08-12 |
CA2669856A1 (en) | 2008-05-29 |
IL198741A0 (en) | 2010-02-17 |
US20090274648A1 (en) | 2009-11-05 |
NO20091871L (no) | 2009-07-31 |
NZ576814A (en) | 2011-06-30 |
JP5241729B2 (ja) | 2013-07-17 |
EA200900697A1 (ru) | 2010-02-26 |
BRPI0719008A2 (pt) | 2013-12-03 |
CO6190510A2 (es) | 2010-08-19 |
AU2007323793A1 (en) | 2008-05-29 |
EA015827B1 (ru) | 2011-12-30 |
ATE546460T1 (de) | 2012-03-15 |
HK1128131A1 (en) | 2009-10-16 |
EP2086995B1 (en) | 2012-02-22 |
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